DE60124686T2 - Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen - Google Patents
Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen Download PDFInfo
- Publication number
- DE60124686T2 DE60124686T2 DE60124686T DE60124686T DE60124686T2 DE 60124686 T2 DE60124686 T2 DE 60124686T2 DE 60124686 T DE60124686 T DE 60124686T DE 60124686 T DE60124686 T DE 60124686T DE 60124686 T2 DE60124686 T2 DE 60124686T2
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- monomer
- polymerization
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- 239000002245 particle Substances 0.000 title claims abstract description 164
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- 239000000463 material Substances 0.000 claims description 55
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- 229920001519 homopolymer Polymers 0.000 description 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 description 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 150000002484 inorganic compounds Chemical class 0.000 description 2
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- 239000010954 inorganic particle Substances 0.000 description 2
- 239000002563 ionic surfactant Substances 0.000 description 2
- QWTDNUCVQCZILF-UHFFFAOYSA-N isopentane Chemical compound CCC(C)C QWTDNUCVQCZILF-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- ACXCWUMCBFSPDP-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;oxiran-2-ylmethyl 2-methylprop-2-enoate Chemical compound COC(=O)C(C)=C.CC(=C)C(=O)OCC1CO1 ACXCWUMCBFSPDP-UHFFFAOYSA-N 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 235000010981 methylcellulose Nutrition 0.000 description 2
- GDOPTJXRTPNYNR-UHFFFAOYSA-N methylcyclopentane Chemical compound CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000006911 nucleation Effects 0.000 description 2
- 239000007764 o/w emulsion Substances 0.000 description 2
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 2
- 150000002989 phenols Chemical class 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 229920005862 polyol Polymers 0.000 description 2
- 150000003077 polyols Chemical class 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 2
- 239000003361 porogen Substances 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 235000010344 sodium nitrate Nutrition 0.000 description 2
- 239000004317 sodium nitrate Substances 0.000 description 2
- 238000010532 solid phase synthesis reaction Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 229920006249 styrenic copolymer Polymers 0.000 description 2
- 150000003464 sulfur compounds Chemical class 0.000 description 2
- OPQYOFWUFGEMRZ-UHFFFAOYSA-N tert-butyl 2,2-dimethylpropaneperoxoate Chemical compound CC(C)(C)OOC(=O)C(C)(C)C OPQYOFWUFGEMRZ-UHFFFAOYSA-N 0.000 description 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- BRQMAAFGEXNUOL-UHFFFAOYSA-N 2-ethylhexyl (2-methylpropan-2-yl)oxy carbonate Chemical compound CCCCC(CC)COC(=O)OOC(C)(C)C BRQMAAFGEXNUOL-UHFFFAOYSA-N 0.000 description 1
- IFSSSYDVRQSDSG-UHFFFAOYSA-N 3-ethenylaniline Chemical compound NC1=CC=CC(C=C)=C1 IFSSSYDVRQSDSG-UHFFFAOYSA-N 0.000 description 1
- RXXCIBALSKQCAE-UHFFFAOYSA-N 3-methylbutoxymethylbenzene Chemical compound CC(C)CCOCC1=CC=CC=C1 RXXCIBALSKQCAE-UHFFFAOYSA-N 0.000 description 1
- PMPVIKIVABFJJI-UHFFFAOYSA-N Cyclobutane Chemical compound C1CCC1 PMPVIKIVABFJJI-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 239000004338 Dichlorodifluoromethane Substances 0.000 description 1
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 108010038807 Oligopeptides Proteins 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002902 bimodal effect Effects 0.000 description 1
- ZFMQKOWCDKKBIF-UHFFFAOYSA-N bis(3,5-difluorophenyl)phosphane Chemical compound FC1=CC(F)=CC(PC=2C=C(F)C=C(F)C=2)=C1 ZFMQKOWCDKKBIF-UHFFFAOYSA-N 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000002666 chemical blowing agent Substances 0.000 description 1
- 125000003636 chemical group Chemical group 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- NEHMKBQYUWJMIP-NJFSPNSNSA-N chloro(114C)methane Chemical compound [14CH3]Cl NEHMKBQYUWJMIP-NJFSPNSNSA-N 0.000 description 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 150000004292 cyclic ethers Chemical class 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 description 1
- 235000019404 dichlorodifluoromethane Nutrition 0.000 description 1
- 229940042935 dichlorodifluoromethane Drugs 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000007720 emulsion polymerization reaction Methods 0.000 description 1
- 229960003750 ethyl chloride Drugs 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 239000012508 resin bead Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
- C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F212/02—Monomers containing only one unsaturated aliphatic radical
- C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
- C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
- C08F212/26—Nitrogen
- C08F212/28—Amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
- C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F285/00—Macromolecular compounds obtained by polymerising monomers on to preformed graft polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Polymerisation Methods In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerization Catalysts (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0007005A GB0007005D0 (en) | 2000-03-22 | 2000-03-22 | Process |
| GB0007005 | 2000-03-22 | ||
| GB0023070A GB0023070D0 (en) | 2000-09-20 | 2000-09-20 | Process |
| GB0023070 | 2000-09-20 | ||
| GB0023673 | 2000-09-27 | ||
| GB0023673A GB0023673D0 (en) | 2000-09-27 | 2000-09-27 | Process |
| PCT/GB2001/001278 WO2001070825A1 (en) | 2000-03-22 | 2001-03-22 | Process for the preparation of functionalised polymer particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60124686D1 DE60124686D1 (de) | 2007-01-04 |
| DE60124686T2 true DE60124686T2 (de) | 2007-09-13 |
Family
ID=27255616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60124686T Expired - Lifetime DE60124686T2 (de) | 2000-03-22 | 2001-03-22 | Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6984702B2 (https=) |
| EP (1) | EP1268563B1 (https=) |
| JP (1) | JP2003528179A (https=) |
| AT (1) | ATE346098T1 (https=) |
| AU (1) | AU2001239422A1 (https=) |
| DE (1) | DE60124686T2 (https=) |
| NO (1) | NO20024517L (https=) |
| WO (1) | WO2001070825A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6984702B2 (en) | 2000-03-22 | 2006-01-10 | Dynal Biotech Asa | Process for the preparation of functionalized polymer particles |
| WO2004089999A2 (en) | 2003-04-14 | 2004-10-21 | Akzo Nobel N.V. | Dosing of peroxide to a suspension process wherein styrene is polymerized |
| CA2532711C (en) | 2003-07-17 | 2013-07-23 | Dynal Biotech Asa | Coating of porous, surface functionalized, superparamagnetic crystal-containing polymer particles with polyisocyanate/diol and/or epoxide monomers |
| NO20041205L (no) * | 2004-03-22 | 2005-09-23 | Polymers Holding As | Lagringsstabile polymer-oligomer partikler og anvendelse av disse i seed polymerisasjon |
| JP5443682B2 (ja) * | 2007-11-05 | 2014-03-19 | 日東電工株式会社 | ヒドロキシ基又は第１級アミノ基を有する多孔質樹脂粒子とその製造方法 |
| WO2009089390A2 (en) * | 2008-01-08 | 2009-07-16 | Bluesky Medical Group Inc. | Sustained variable negative pressure wound treatment and method of controlling same |
| WO2010066454A2 (en) | 2008-12-12 | 2010-06-17 | Jackon Gmbh | Process for the preparation of an expandable polymer composition in the form of beads |
| DK2356173T3 (en) | 2008-12-12 | 2018-08-27 | Jackon Gmbh | PROCEDURE FOR THE PREPARATION OF AN EXPANDABLE POLYMER COMPOSITION IN THE FORM OF BALLS |
| US8790916B2 (en) | 2009-05-14 | 2014-07-29 | Genestream, Inc. | Microfluidic method and system for isolating particles from biological fluid |
| EP2581392B1 (en) * | 2010-06-10 | 2018-05-30 | Mitsubishi Chemical Corporation | Process for production of acrylic polymer, acrylic polymer obtained by the process, and plastisol composition using same |
| US8747084B2 (en) | 2010-07-21 | 2014-06-10 | Aperia Technologies, Inc. | Peristaltic pump |
| WO2013037770A1 (en) * | 2011-09-15 | 2013-03-21 | Bayer Intellectual Property Gmbh | Method for the continuous production of water-dispersible vinyl polymers |
| US9222473B2 (en) | 2012-03-20 | 2015-12-29 | Aperia Technologies, Inc. | Passive pressure regulation mechanism |
| US9604157B2 (en) | 2013-03-12 | 2017-03-28 | Aperia Technologies, Inc. | Pump with water management |
| US10245908B2 (en) | 2016-09-06 | 2019-04-02 | Aperia Technologies, Inc. | System for tire inflation |
| US10144254B2 (en) | 2013-03-12 | 2018-12-04 | Aperia Technologies, Inc. | Tire inflation system |
| US11453258B2 (en) | 2013-03-12 | 2022-09-27 | Aperia Technologies, Inc. | System for tire inflation |
| US10406869B2 (en) | 2017-11-10 | 2019-09-10 | Aperia Technologies, Inc. | Inflation system |
| US11642920B2 (en) | 2018-11-27 | 2023-05-09 | Aperia Technologies, Inc. | Hub-integrated inflation system |
| US12442364B2 (en) | 2023-12-11 | 2025-10-14 | Aperia Technologies, Inc. | Two-stage pump and method of operation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU530410B2 (en) | 1978-02-21 | 1983-07-14 | Sintef | Preparing aqueous emulsions |
| NO149108C (no) * | 1981-10-21 | 1984-02-15 | Sintef | Fremgangsmaate for fremstilling av vandige dispersjoner av organisk materiale og eventuelt videre omdannelse til en polymerdispersjon naar det organiske materiale er en polymeriserbar monomer |
| JPS61215604A (ja) * | 1985-03-22 | 1986-09-25 | Japan Synthetic Rubber Co Ltd | ポリマ−粒子の製造方法 |
| JPS62181301A (ja) * | 1986-02-06 | 1987-08-08 | Fuji Xerox Co Ltd | 重合体粒子の製造方法 |
| JP2768475B2 (ja) * | 1988-11-21 | 1998-06-25 | 三井化学株式会社 | 変性ポリオレフィン粒子の製造法 |
| US5212251A (en) * | 1990-09-24 | 1993-05-18 | Rohm And Haas Company | Alkali-resistant core-shell polymers |
| JPH08134115A (ja) * | 1994-11-15 | 1996-05-28 | Sekisui Chem Co Ltd | 高単分散微粒子の製造方法 |
| GB9721603D0 (en) * | 1997-10-10 | 1997-12-10 | Dyno Ind Asa | Method |
| TW515816B (en) | 1997-10-10 | 2003-01-01 | Polymer Systems As | Method of production of particulate polymers |
| US6559217B1 (en) * | 1999-04-09 | 2003-05-06 | Polymer Systems As | Preparation of polymer particles |
| US6984702B2 (en) | 2000-03-22 | 2006-01-10 | Dynal Biotech Asa | Process for the preparation of functionalized polymer particles |
-
2001
- 2001-03-01 US US10/239,492 patent/US6984702B2/en not_active Expired - Lifetime
- 2001-03-22 JP JP2001569025A patent/JP2003528179A/ja active Pending
- 2001-03-22 WO PCT/GB2001/001278 patent/WO2001070825A1/en not_active Ceased
- 2001-03-22 AT AT01914034T patent/ATE346098T1/de not_active IP Right Cessation
- 2001-03-22 EP EP01914034A patent/EP1268563B1/en not_active Expired - Lifetime
- 2001-03-22 AU AU2001239422A patent/AU2001239422A1/en not_active Abandoned
- 2001-03-22 DE DE60124686T patent/DE60124686T2/de not_active Expired - Lifetime
-
2002
- 2002-09-20 NO NO20024517A patent/NO20024517L/no unknown
-
2005
- 2005-11-14 US US11/273,438 patent/US20060069217A1/en not_active Abandoned
-
2007
- 2007-08-21 US US11/842,836 patent/US7763689B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1268563B1 (en) | 2006-11-22 |
| DE60124686D1 (de) | 2007-01-04 |
| WO2001070825A1 (en) | 2001-09-27 |
| US7763689B2 (en) | 2010-07-27 |
| US6984702B2 (en) | 2006-01-10 |
| ATE346098T1 (de) | 2006-12-15 |
| NO20024517D0 (no) | 2002-09-20 |
| US20060069217A1 (en) | 2006-03-30 |
| NO20024517L (no) | 2002-11-22 |
| AU2001239422A1 (en) | 2001-10-03 |
| EP1268563A1 (en) | 2003-01-02 |
| JP2003528179A (ja) | 2003-09-24 |
| US20030109657A1 (en) | 2003-06-12 |
| US20080039578A1 (en) | 2008-02-14 |
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| 8364 | No opposition during term of opposition |