DE60124686T2 - Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen - Google Patents
Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen Download PDFInfo
- Publication number
- DE60124686T2 DE60124686T2 DE60124686T DE60124686T DE60124686T2 DE 60124686 T2 DE60124686 T2 DE 60124686T2 DE 60124686 T DE60124686 T DE 60124686T DE 60124686 T DE60124686 T DE 60124686T DE 60124686 T2 DE60124686 T2 DE 60124686T2
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- monomer
- polymerization
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- 239000002245 particle Substances 0.000 title claims abstract description 164
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- 239000000463 material Substances 0.000 claims description 55
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- 229920001519 homopolymer Polymers 0.000 description 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 description 2
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- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 150000002484 inorganic compounds Chemical class 0.000 description 2
- 239000011147 inorganic material Substances 0.000 description 2
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- 239000002563 ionic surfactant Substances 0.000 description 2
- QWTDNUCVQCZILF-UHFFFAOYSA-N isopentane Chemical compound CCC(C)C QWTDNUCVQCZILF-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- ACXCWUMCBFSPDP-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;oxiran-2-ylmethyl 2-methylprop-2-enoate Chemical compound COC(=O)C(C)=C.CC(=C)C(=O)OCC1CO1 ACXCWUMCBFSPDP-UHFFFAOYSA-N 0.000 description 2
- 229920000609 methyl cellulose Polymers 0.000 description 2
- 235000010981 methylcellulose Nutrition 0.000 description 2
- GDOPTJXRTPNYNR-UHFFFAOYSA-N methylcyclopentane Chemical compound CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000006911 nucleation Effects 0.000 description 2
- 239000007764 o/w emulsion Substances 0.000 description 2
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 2
- 150000002989 phenols Chemical class 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 229920005862 polyol Polymers 0.000 description 2
- 150000003077 polyols Chemical class 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 229920002451 polyvinyl alcohol Polymers 0.000 description 2
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 2
- 239000003361 porogen Substances 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 230000035484 reaction time Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 235000010344 sodium nitrate Nutrition 0.000 description 2
- 239000004317 sodium nitrate Substances 0.000 description 2
- 238000010532 solid phase synthesis reaction Methods 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 229920006249 styrenic copolymer Polymers 0.000 description 2
- 150000003464 sulfur compounds Chemical class 0.000 description 2
- OPQYOFWUFGEMRZ-UHFFFAOYSA-N tert-butyl 2,2-dimethylpropaneperoxoate Chemical compound CC(C)(C)OOC(=O)C(C)(C)C OPQYOFWUFGEMRZ-UHFFFAOYSA-N 0.000 description 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 2
- 239000001993 wax Substances 0.000 description 2
- BRQMAAFGEXNUOL-UHFFFAOYSA-N 2-ethylhexyl (2-methylpropan-2-yl)oxy carbonate Chemical compound CCCCC(CC)COC(=O)OOC(C)(C)C BRQMAAFGEXNUOL-UHFFFAOYSA-N 0.000 description 1
- IFSSSYDVRQSDSG-UHFFFAOYSA-N 3-ethenylaniline Chemical compound NC1=CC=CC(C=C)=C1 IFSSSYDVRQSDSG-UHFFFAOYSA-N 0.000 description 1
- RXXCIBALSKQCAE-UHFFFAOYSA-N 3-methylbutoxymethylbenzene Chemical compound CC(C)CCOCC1=CC=CC=C1 RXXCIBALSKQCAE-UHFFFAOYSA-N 0.000 description 1
- PMPVIKIVABFJJI-UHFFFAOYSA-N Cyclobutane Chemical compound C1CCC1 PMPVIKIVABFJJI-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 239000004338 Dichlorodifluoromethane Substances 0.000 description 1
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 108010038807 Oligopeptides Proteins 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002902 bimodal effect Effects 0.000 description 1
- ZFMQKOWCDKKBIF-UHFFFAOYSA-N bis(3,5-difluorophenyl)phosphane Chemical compound FC1=CC(F)=CC(PC=2C=C(F)C=C(F)C=2)=C1 ZFMQKOWCDKKBIF-UHFFFAOYSA-N 0.000 description 1
- 239000001273 butane Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000002666 chemical blowing agent Substances 0.000 description 1
- 125000003636 chemical group Chemical group 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- NEHMKBQYUWJMIP-NJFSPNSNSA-N chloro(114C)methane Chemical compound [14CH3]Cl NEHMKBQYUWJMIP-NJFSPNSNSA-N 0.000 description 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 150000004292 cyclic ethers Chemical class 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- PXBRQCKWGAHEHS-UHFFFAOYSA-N dichlorodifluoromethane Chemical compound FC(F)(Cl)Cl PXBRQCKWGAHEHS-UHFFFAOYSA-N 0.000 description 1
- 235000019404 dichlorodifluoromethane Nutrition 0.000 description 1
- 229940042935 dichlorodifluoromethane Drugs 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000007720 emulsion polymerization reaction Methods 0.000 description 1
- 229960003750 ethyl chloride Drugs 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 239000012508 resin bead Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
- C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
- C08F212/02—Monomers containing only one unsaturated aliphatic radical
- C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
- C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
- C08F212/26—Nitrogen
- C08F212/28—Amines
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F257/00—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00
- C08F257/02—Macromolecular compounds obtained by polymerising monomers on to polymers of aromatic monomers as defined in group C08F12/00 on to polymers of styrene or alkyl-substituted styrenes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F285/00—Macromolecular compounds obtained by polymerising monomers on to preformed graft polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Polymerisation Methods In General (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polymerization Catalysts (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0007005A GB0007005D0 (en) | 2000-03-22 | 2000-03-22 | Process |
| GB0007005 | 2000-03-22 | ||
| GB0023070 | 2000-09-20 | ||
| GB0023070A GB0023070D0 (en) | 2000-09-20 | 2000-09-20 | Process |
| GB0023673A GB0023673D0 (en) | 2000-09-27 | 2000-09-27 | Process |
| GB0023673 | 2000-09-27 | ||
| PCT/GB2001/001278 WO2001070825A1 (en) | 2000-03-22 | 2001-03-22 | Process for the preparation of functionalised polymer particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60124686D1 DE60124686D1 (de) | 2007-01-04 |
| DE60124686T2 true DE60124686T2 (de) | 2007-09-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60124686T Expired - Lifetime DE60124686T2 (de) | 2000-03-22 | 2001-03-22 | Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6984702B2 (enExample) |
| EP (1) | EP1268563B1 (enExample) |
| JP (1) | JP2003528179A (enExample) |
| AT (1) | ATE346098T1 (enExample) |
| AU (1) | AU2001239422A1 (enExample) |
| DE (1) | DE60124686T2 (enExample) |
| NO (1) | NO20024517L (enExample) |
| WO (1) | WO2001070825A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6984702B2 (en) | 2000-03-22 | 2006-01-10 | Dynal Biotech Asa | Process for the preparation of functionalized polymer particles |
| WO2004089999A2 (en) | 2003-04-14 | 2004-10-21 | Akzo Nobel N.V. | Dosing of peroxide to a suspension process wherein styrene is polymerized |
| CN102746529B (zh) | 2003-07-17 | 2015-11-18 | 生命科技公司 | 包覆的磁性颗粒的制备方法 |
| NO20041205L (no) * | 2004-03-22 | 2005-09-23 | Polymers Holding As | Lagringsstabile polymer-oligomer partikler og anvendelse av disse i seed polymerisasjon |
| JP5443682B2 (ja) * | 2007-11-05 | 2014-03-19 | 日東電工株式会社 | ヒドロキシ基又は第１級アミノ基を有する多孔質樹脂粒子とその製造方法 |
| WO2009089390A2 (en) * | 2008-01-08 | 2009-07-16 | Bluesky Medical Group Inc. | Sustained variable negative pressure wound treatment and method of controlling same |
| DK2364329T3 (da) | 2008-12-12 | 2019-01-02 | Jackon Gmbh | Fremgangsmåde til fremstillingen af en ekspanderbar polymersammensætning i form af perler |
| DK2356173T3 (en) | 2008-12-12 | 2018-08-27 | Jackon Gmbh | PROCEDURE FOR THE PREPARATION OF AN EXPANDABLE POLYMER COMPOSITION IN THE FORM OF BALLS |
| US8790916B2 (en) | 2009-05-14 | 2014-07-29 | Genestream, Inc. | Microfluidic method and system for isolating particles from biological fluid |
| WO2011155566A1 (ja) * | 2010-06-10 | 2011-12-15 | 三菱レイヨン株式会社 | アクリル系重合体の製造方法、この製造方法により得られるアクリル系重合体及びこれを用いたプラスチゾル組成物 |
| US8747084B2 (en) | 2010-07-21 | 2014-06-10 | Aperia Technologies, Inc. | Peristaltic pump |
| WO2013037770A1 (en) * | 2011-09-15 | 2013-03-21 | Bayer Intellectual Property Gmbh | Method for the continuous production of water-dispersible vinyl polymers |
| BR112014022974B1 (pt) | 2012-03-20 | 2021-08-17 | Aperia Technologies | Sistema de inflagem de pneu |
| US10144254B2 (en) | 2013-03-12 | 2018-12-04 | Aperia Technologies, Inc. | Tire inflation system |
| US11453258B2 (en) | 2013-03-12 | 2022-09-27 | Aperia Technologies, Inc. | System for tire inflation |
| US9604157B2 (en) | 2013-03-12 | 2017-03-28 | Aperia Technologies, Inc. | Pump with water management |
| MX2019002569A (es) | 2016-09-06 | 2019-10-07 | Aperia Tech Inc | Sistema para inflado de neumáticos. |
| US10406869B2 (en) | 2017-11-10 | 2019-09-10 | Aperia Technologies, Inc. | Inflation system |
| US11642920B2 (en) | 2018-11-27 | 2023-05-09 | Aperia Technologies, Inc. | Hub-integrated inflation system |
| US12442364B2 (en) | 2023-12-11 | 2025-10-14 | Aperia Technologies, Inc. | Two-stage pump and method of operation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU530410B2 (en) | 1978-02-21 | 1983-07-14 | Sintef | Preparing aqueous emulsions |
| NO149108C (no) * | 1981-10-21 | 1984-02-15 | Sintef | Fremgangsmaate for fremstilling av vandige dispersjoner av organisk materiale og eventuelt videre omdannelse til en polymerdispersjon naar det organiske materiale er en polymeriserbar monomer |
| JPS61215604A (ja) * | 1985-03-22 | 1986-09-25 | Japan Synthetic Rubber Co Ltd | ポリマ−粒子の製造方法 |
| JPS62181301A (ja) * | 1986-02-06 | 1987-08-08 | Fuji Xerox Co Ltd | 重合体粒子の製造方法 |
| JP2768475B2 (ja) * | 1988-11-21 | 1998-06-25 | 三井化学株式会社 | 変性ポリオレフィン粒子の製造法 |
| US5212251A (en) * | 1990-09-24 | 1993-05-18 | Rohm And Haas Company | Alkali-resistant core-shell polymers |
| JPH08134115A (ja) * | 1994-11-15 | 1996-05-28 | Sekisui Chem Co Ltd | 高単分散微粒子の製造方法 |
| TW515816B (en) | 1997-10-10 | 2003-01-01 | Polymer Systems As | Method of production of particulate polymers |
| GB9721603D0 (en) * | 1997-10-10 | 1997-12-10 | Dyno Ind Asa | Method |
| PL198386B1 (pl) * | 1999-04-09 | 2008-06-30 | Polymer Systems As | Sposób wytwarzania polimeru w postaci cząstek |
| US6984702B2 (en) | 2000-03-22 | 2006-01-10 | Dynal Biotech Asa | Process for the preparation of functionalized polymer particles |
-
2001
- 2001-03-01 US US10/239,492 patent/US6984702B2/en not_active Expired - Lifetime
- 2001-03-22 WO PCT/GB2001/001278 patent/WO2001070825A1/en not_active Ceased
- 2001-03-22 DE DE60124686T patent/DE60124686T2/de not_active Expired - Lifetime
- 2001-03-22 AU AU2001239422A patent/AU2001239422A1/en not_active Abandoned
- 2001-03-22 AT AT01914034T patent/ATE346098T1/de not_active IP Right Cessation
- 2001-03-22 JP JP2001569025A patent/JP2003528179A/ja active Pending
- 2001-03-22 EP EP01914034A patent/EP1268563B1/en not_active Expired - Lifetime
-
2002
- 2002-09-20 NO NO20024517A patent/NO20024517L/no unknown
-
2005
- 2005-11-14 US US11/273,438 patent/US20060069217A1/en not_active Abandoned
-
2007
- 2007-08-21 US US11/842,836 patent/US7763689B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003528179A (ja) | 2003-09-24 |
| NO20024517L (no) | 2002-11-22 |
| EP1268563B1 (en) | 2006-11-22 |
| EP1268563A1 (en) | 2003-01-02 |
| NO20024517D0 (no) | 2002-09-20 |
| US20060069217A1 (en) | 2006-03-30 |
| US20080039578A1 (en) | 2008-02-14 |
| AU2001239422A1 (en) | 2001-10-03 |
| US6984702B2 (en) | 2006-01-10 |
| US7763689B2 (en) | 2010-07-27 |
| ATE346098T1 (de) | 2006-12-15 |
| US20030109657A1 (en) | 2003-06-12 |
| WO2001070825A1 (en) | 2001-09-27 |
| DE60124686D1 (de) | 2007-01-04 |
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| 8364 | No opposition during term of opposition |