DE60110975D1 - Acylierungsverfahren - Google Patents
AcylierungsverfahrenInfo
- Publication number
- DE60110975D1 DE60110975D1 DE60110975T DE60110975T DE60110975D1 DE 60110975 D1 DE60110975 D1 DE 60110975D1 DE 60110975 T DE60110975 T DE 60110975T DE 60110975 T DE60110975 T DE 60110975T DE 60110975 D1 DE60110975 D1 DE 60110975D1
- Authority
- DE
- Germany
- Prior art keywords
- acylate
- tocol
- tocopherol
- reaction mixture
- acylation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000010933 acylation Effects 0.000 title 1
- 238000005917 acylation reaction Methods 0.000 title 1
- ODIGIKRIUKFKHP-UHFFFAOYSA-N (n-propan-2-yloxycarbonylanilino) acetate Chemical compound CC(C)OC(=O)N(OC(C)=O)C1=CC=CC=C1 ODIGIKRIUKFKHP-UHFFFAOYSA-N 0.000 abstract 6
- DFUSDJMZWQVQSF-XLGIIRLISA-N (2r)-2-methyl-2-[(4r,8r)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol Chemical compound OC1=CC=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 DFUSDJMZWQVQSF-XLGIIRLISA-N 0.000 abstract 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 4
- 229960001295 tocopherol Drugs 0.000 abstract 4
- 229930003799 tocopherol Natural products 0.000 abstract 4
- 235000010384 tocopherol Nutrition 0.000 abstract 4
- 239000011732 tocopherol Substances 0.000 abstract 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 4
- 239000011541 reaction mixture Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00114768 | 2000-07-10 | ||
| EP00114768 | 2000-07-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60110975D1 true DE60110975D1 (de) | 2005-06-30 |
| DE60110975T2 DE60110975T2 (de) | 2005-10-27 |
Family
ID=8169206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60110975T Expired - Lifetime DE60110975T2 (de) | 2000-07-10 | 2001-07-02 | Acylierungsverfahren |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6444098B2 (de) |
| JP (1) | JP2002047284A (de) |
| KR (1) | KR100798506B1 (de) |
| CN (1) | CN1200937C (de) |
| AT (1) | ATE296299T1 (de) |
| BR (1) | BR0102769A (de) |
| CA (1) | CA2352447A1 (de) |
| DE (1) | DE60110975T2 (de) |
| ES (1) | ES2241718T3 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1689733B1 (de) * | 2003-12-05 | 2008-10-15 | DSM IP Assets B.V. | Verfahren zur herstellung von alkenylierten hydroxylierten aromatischen verbindungen, von chromanverbindungen und deren acylierten derivaten |
| JP4909534B2 (ja) * | 2005-06-23 | 2012-04-04 | 住友化学株式会社 | ポリエステル及びその製造方法 |
| JP5077908B2 (ja) * | 2006-02-07 | 2012-11-21 | 独立行政法人産業技術総合研究所 | アシル化トコフェロールの製造法 |
| EP2882729B1 (de) * | 2012-08-10 | 2016-09-21 | DSM IP Assets B.V. | Geschütztes tocopherol mit reduziertem anteil an freien tocopherolen |
| CN104016856A (zh) * | 2014-02-21 | 2014-09-03 | 华东理工大学 | 芳香族化合物上的羟基乙酰化的方法 |
| CN105801551B (zh) * | 2014-12-29 | 2018-11-30 | 浙江新和成药业有限公司 | 一种维生素e醋酸酯的清洁生产方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2723278A (en) | 1954-01-25 | 1955-11-08 | Hoffmann La Roche | Preparation of alpha-tocopherol |
| FR2666581B1 (fr) | 1990-09-06 | 1993-05-28 | Rhone Poulenc Nutrition Animal | Procede de preparation d'acetate de tocopherol. |
| JPH06145200A (ja) * | 1992-09-11 | 1994-05-24 | Maruha Corp | アシル化ゼラチンの製造方法 |
| CN1211243A (zh) | 1996-01-29 | 1999-03-17 | Basf公司 | dl－α－生育酚或乙酸dl－α－生育酚酯的制备 |
| FR2760744B1 (fr) | 1997-03-12 | 1999-04-23 | Rhodia Chimie Sa | Procede d'acylation d'un compose aromatique |
| KR100408991B1 (ko) * | 2000-03-23 | 2003-12-11 | 에스케이 주식회사 | ＤＬ-α-토코페롤 아세테이트의 제조방법 |
-
2001
- 2001-07-02 AT AT01116014T patent/ATE296299T1/de not_active IP Right Cessation
- 2001-07-02 ES ES01116014T patent/ES2241718T3/es not_active Expired - Lifetime
- 2001-07-02 DE DE60110975T patent/DE60110975T2/de not_active Expired - Lifetime
- 2001-07-05 CA CA002352447A patent/CA2352447A1/en not_active Abandoned
- 2001-07-06 BR BR0102769-7A patent/BR0102769A/pt not_active Application Discontinuation
- 2001-07-09 JP JP2001207414A patent/JP2002047284A/ja not_active Withdrawn
- 2001-07-09 US US09/900,587 patent/US6444098B2/en not_active Expired - Fee Related
- 2001-07-10 KR KR1020010041096A patent/KR100798506B1/ko not_active IP Right Cessation
- 2001-07-10 CN CNB011228237A patent/CN1200937C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020005510A (ko) | 2002-01-17 |
| JP2002047284A (ja) | 2002-02-12 |
| CA2352447A1 (en) | 2002-01-10 |
| KR100798506B1 (ko) | 2008-01-28 |
| US20020017451A1 (en) | 2002-02-14 |
| BR0102769A (pt) | 2002-02-26 |
| CN1200937C (zh) | 2005-05-11 |
| CN1332164A (zh) | 2002-01-23 |
| ES2241718T3 (es) | 2005-11-01 |
| US6444098B2 (en) | 2002-09-03 |
| DE60110975T2 (de) | 2005-10-27 |
| ATE296299T1 (de) | 2005-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |