DE60109605D1 - Triterpen-derivate und ihre verwendung als antiproliferative wirkstoffe - Google Patents

Triterpen-derivate und ihre verwendung als antiproliferative wirkstoffe

Info

Publication number
DE60109605D1
DE60109605D1 DE60109605T DE60109605T DE60109605D1 DE 60109605 D1 DE60109605 D1 DE 60109605D1 DE 60109605 T DE60109605 T DE 60109605T DE 60109605 T DE60109605 T DE 60109605T DE 60109605 D1 DE60109605 D1 DE 60109605D1
Authority
DE
Germany
Prior art keywords
formula
triterpen
derivatives
active substances
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109605T
Other languages
English (en)
Other versions
DE60109605T2 (de
Inventor
Marian Hajduch
Jan Sarek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Karlova Univerzita v Praze
Univerzita Palackeho V Olomouci
Original Assignee
Karlova Univerzita v Praze
Univerzita Palackeho V Olomouci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0012532A external-priority patent/GB0012532D0/en
Priority claimed from GB0012825A external-priority patent/GB2362650A/en
Application filed by Karlova Univerzita v Praze, Univerzita Palackeho V Olomouci filed Critical Karlova Univerzita v Praze
Publication of DE60109605D1 publication Critical patent/DE60109605D1/de
Application granted granted Critical
Publication of DE60109605T2 publication Critical patent/DE60109605T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE60109605T 2000-05-23 2001-05-23 Triterpen-derivate und ihre verwendung als antiproliferative wirkstoffe Expired - Lifetime DE60109605T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0012532 2000-05-23
GB0012532A GB0012532D0 (en) 2000-05-23 2000-05-23 Triterpenoid derivatives
GB0012825 2000-05-25
GB0012825A GB2362650A (en) 2000-05-25 2000-05-25 Triterpenoid derivatives
PCT/GB2001/002341 WO2001090096A2 (en) 2000-05-23 2001-05-23 Triterpenoid derivatives and their use as antiproliferative agents

Publications (2)

Publication Number Publication Date
DE60109605D1 true DE60109605D1 (de) 2005-04-28
DE60109605T2 DE60109605T2 (de) 2006-02-02

Family

ID=26244333

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109605T Expired - Lifetime DE60109605T2 (de) 2000-05-23 2001-05-23 Triterpen-derivate und ihre verwendung als antiproliferative wirkstoffe

Country Status (5)

Country Link
EP (1) EP1289977B1 (de)
AT (1) ATE291573T1 (de)
AU (1) AU2001258631A1 (de)
DE (1) DE60109605T2 (de)
WO (1) WO2001090096A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2008723A3 (cs) 2008-11-13 2010-01-13 Univerzita Palackého v Olomouci 2-Deoxyglykosidy triterpenoidu, zpusob jejich prípravy a jejich použití jako lécivo
CN105534995B (zh) * 2016-02-24 2018-05-18 上海交通大学医学院附属仁济医院 化合物Hu-17单独或联合酪氨酸激酶抑制剂在制备治疗慢性粒细胞白血病药物中的应用
CN109180775B (zh) * 2018-09-05 2021-03-23 常州大学怀德学院 C-28亚胺取代白桦脂醇异构体衍生物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0902685A1 (de) * 1997-01-24 1999-03-24 Marigen S.A. Ultramikroemulsionen aus spontan dispergierbaren konzentraten enthaltend antitumoral, antiviral und antiparasitär wirksame ester von pentacyclischen triterpenen

Also Published As

Publication number Publication date
WO2001090096A2 (en) 2001-11-29
EP1289977B1 (de) 2005-03-23
WO2001090096A3 (en) 2002-03-07
AU2001258631A1 (en) 2001-12-03
ATE291573T1 (de) 2005-04-15
DE60109605T2 (de) 2006-02-02
EP1289977A2 (de) 2003-03-12

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