DE60103249D1 - Verteilungsvorrichtung für einen kapillarreaktor und verfahren - Google Patents
Verteilungsvorrichtung für einen kapillarreaktor und verfahrenInfo
- Publication number
- DE60103249D1 DE60103249D1 DE60103249T DE60103249T DE60103249D1 DE 60103249 D1 DE60103249 D1 DE 60103249D1 DE 60103249 T DE60103249 T DE 60103249T DE 60103249 T DE60103249 T DE 60103249T DE 60103249 D1 DE60103249 D1 DE 60103249D1
- Authority
- DE
- Germany
- Prior art keywords
- capillary
- slugs
- fluids
- distribution device
- pathways
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
- B01F25/23—Mixing by intersecting jets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
- B01F33/3022—Micromixers the materials to be mixed flowing in the form of droplets the components being formed by independent droplets which are alternated, the mixing of the components being achieved by diffusion between droplets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/836—Mixing plants; Combinations of mixers combining mixing with other treatments
- B01F33/8362—Mixing plants; Combinations of mixers combining mixing with other treatments with chemical reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/565—Seals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00801—Means to assemble
- B01J2219/0081—Plurality of modules
- B01J2219/00813—Fluidic connections
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00833—Plastic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00819—Materials of construction
- B01J2219/00835—Comprising catalytically active material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00905—Separation
- B01J2219/00909—Separation using filters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0396—Involving pressure control
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2082—Utilizing particular fluid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2224—Structure of body of device
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0004958A GB2359765B (en) | 2000-03-02 | 2000-03-02 | Capillary reactor distribution device and method |
GB0004958 | 2000-03-02 | ||
PCT/GB2001/000848 WO2001064332A1 (en) | 2000-03-02 | 2001-03-01 | Capillary reactor distribution device and method |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60103249D1 true DE60103249D1 (de) | 2004-06-17 |
DE60103249T2 DE60103249T2 (de) | 2005-05-25 |
Family
ID=9886757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60103249T Expired - Lifetime DE60103249T2 (de) | 2000-03-02 | 2001-03-01 | Verteilungsvorrichtung für einen kapillarreaktor und verfahren |
Country Status (8)
Country | Link |
---|---|
US (1) | US7032607B2 (de) |
EP (1) | EP1259316B1 (de) |
JP (1) | JP2003525116A (de) |
AT (1) | ATE266466T1 (de) |
AU (1) | AU2001235792A1 (de) |
DE (1) | DE60103249T2 (de) |
GB (1) | GB2359765B (de) |
WO (1) | WO2001064332A1 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60214604T2 (de) * | 2001-02-23 | 2006-12-28 | Japan Science And Technology Agency, Kawaguchi | Vorrichtung und Verfahren zum Herstellen von Mikrokapseln |
GB0123114D0 (en) * | 2001-09-26 | 2001-11-14 | Accentus Plc | Protein production |
US7718099B2 (en) | 2002-04-25 | 2010-05-18 | Tosoh Corporation | Fine channel device, fine particle producing method and solvent extraction method |
FR2839504B1 (fr) | 2002-05-07 | 2004-06-18 | Commissariat Energie Atomique | Dispositif et procede de distribution de produits liquides |
EP2283917B1 (de) * | 2002-05-09 | 2021-12-15 | The University of Chicago | Vorrichtung zum druckbetriebenen Transport durch Einstecken und Reaktion |
US7901939B2 (en) | 2002-05-09 | 2011-03-08 | University Of Chicago | Method for performing crystallization and reactions in pressure-driven fluid plugs |
WO2004040645A1 (en) * | 2002-10-31 | 2004-05-13 | Stichting Voor De Technische Wetenschappen | Microfluidic heat exchanger for locatized temperature control |
GB2395196B (en) * | 2002-11-14 | 2006-12-27 | Univ Cardiff | Microfluidic device and methods for construction and application |
US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
JP2004337649A (ja) * | 2003-05-13 | 2004-12-02 | Hitachi Ltd | 有機塩素化合物処理装置 |
EP1711263A2 (de) * | 2003-12-10 | 2006-10-18 | Northeastern University | Verfahren zum effizienten transport kleiner flüssigkeitsvolumina zu, weg von oder innerhalb von mikrofluidischen vorrichtungen |
US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
US7802923B2 (en) * | 2004-04-02 | 2010-09-28 | Ab Sciex Llc | Microfluidic connections |
US9477233B2 (en) | 2004-07-02 | 2016-10-25 | The University Of Chicago | Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets |
US7655470B2 (en) | 2004-10-29 | 2010-02-02 | University Of Chicago | Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems |
DE102004038555B3 (de) * | 2004-08-06 | 2005-08-04 | Plinke Gmbh | Modularer Mikroreaktor zur Nitrierung mit Mischsäure |
CN102513170B (zh) * | 2004-09-09 | 2015-03-25 | 居里研究所 | 用于在微容器特别是微通道中操纵小包的装置 |
US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
DE102004049730B4 (de) * | 2004-10-11 | 2007-05-03 | Technische Universität Darmstadt | Mikrokapillarreaktor und Verfahren zum kontrollierten Vermengen von nicht homogen mischbaren Fluiden unter Verwendung dieses Mikrokapillarreaktors |
EP1857173A4 (de) * | 2005-02-21 | 2010-05-05 | Univ Okayama Nat Univ Corp | Strömungseinstellungsvorrichtung, mikroreaktor und verwendung davon |
US7795359B2 (en) * | 2005-03-04 | 2010-09-14 | Novartis Ag | Continuous process for production of polymeric materials |
US8354069B2 (en) | 2005-03-08 | 2013-01-15 | Authentix, Inc. | Plug flow system for identification and authentication of markers |
CN1326605C (zh) * | 2005-07-08 | 2007-07-18 | 清华大学 | 一种多通道微结构反应器 |
WO2007021818A2 (en) * | 2005-08-11 | 2007-02-22 | Smithkline Beecham Corporation | Flow reactor method and apparatus |
WO2007024778A2 (en) * | 2005-08-22 | 2007-03-01 | Applera Corporation | Device, system and method for depositing processed immiscible-fluid-discrete-volumes |
DE102005055866A1 (de) * | 2005-11-23 | 2007-05-24 | Hte Ag The High Throughput Experimentation Company | Verfahren zur Herstellung von Aryl-Aryl gekoppelter Verbindungen |
US20100137163A1 (en) | 2006-01-11 | 2010-06-03 | Link Darren R | Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors |
JP2009523136A (ja) * | 2006-01-12 | 2009-06-18 | ロンザ ア−ゲ− | マイクロリアクターでの活性化された芳香族のニトロ化 |
WO2007133710A2 (en) | 2006-05-11 | 2007-11-22 | Raindance Technologies, Inc. | Microfluidic devices and methods of use thereof |
US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
US7666950B2 (en) * | 2006-06-01 | 2010-02-23 | Lanxess Deutschland Gmbh | Process for preparing hydrogenated nitrile rubbers |
WO2008021123A1 (en) | 2006-08-07 | 2008-02-21 | President And Fellows Of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
JP5232983B2 (ja) * | 2007-03-16 | 2013-07-10 | 国立大学法人 岡山大学 | マイクロミキサー |
JP5223065B2 (ja) * | 2007-03-16 | 2013-06-26 | 国立大学法人 岡山大学 | マイクロミキサー |
WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
GB0810990D0 (en) | 2008-06-16 | 2008-07-23 | Q Chip Ltd | Device and method of making solid beads |
EP2315629B1 (de) | 2008-07-18 | 2021-12-15 | Bio-Rad Laboratories, Inc. | Tröpfchenbibliotheken |
DE102009054532A1 (de) | 2008-12-22 | 2010-07-01 | Basf Se | Verfahren zur Herstellung von Partikeln umfassend wasserlösliche Polymere |
EP2411148B1 (de) | 2009-03-23 | 2018-02-21 | Raindance Technologies, Inc. | Manipulation von mikrofluidiktröpfchen |
KR101097357B1 (ko) * | 2009-07-09 | 2011-12-23 | 한국과학기술원 | 다기능 미세유체 유동 제어 장치 및 다기능 미세유체 유동 제어 방법 |
EP2486409A1 (de) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Markiertes nanomaterial auf siliziumbasis mit verbesserten eigenschaften und seine verwendung |
US10837883B2 (en) | 2009-12-23 | 2020-11-17 | Bio-Rad Laboratories, Inc. | Microfluidic systems and methods for reducing the exchange of molecules between droplets |
US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
US8535889B2 (en) | 2010-02-12 | 2013-09-17 | Raindance Technologies, Inc. | Digital analyte analysis |
US8197670B2 (en) * | 2010-02-23 | 2012-06-12 | Chevron U.S.A. Inc. | Process for upgrading hydrocarbons and device for use therein |
WO2011146425A1 (en) * | 2010-05-17 | 2011-11-24 | Ohio University | Microsecond time-resolved mass spectrometry |
EP3447155A1 (de) | 2010-09-30 | 2019-02-27 | Raindance Technologies, Inc. | Sandwichassays in tröpfchen |
EP3859011A1 (de) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Verfahren zur bildung gemischter tröpfchen |
WO2012112804A1 (en) | 2011-02-18 | 2012-08-23 | Raindance Technoligies, Inc. | Compositions and methods for molecular labeling |
US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
EP3216872B1 (de) | 2011-06-02 | 2020-04-01 | Bio-Rad Laboratories, Inc. | Enzymquantifizierung |
US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
EP3088006A1 (de) * | 2015-04-28 | 2016-11-02 | Bayer Technology Services GmbH | Verfahren zur kontinuierlichen virusinaktivierung in einem mikroreaktor |
EP3331643A1 (de) * | 2015-08-06 | 2018-06-13 | hte GmbH the high throughput experimentation company | Strömungselement mit integrierter kapillarleitung zur überführung von fluiden |
US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
US10215721B2 (en) * | 2016-03-04 | 2019-02-26 | David N. BREWER | Pressurizable dilatometer system and apparatus |
KR101886645B1 (ko) * | 2016-05-03 | 2018-08-08 | 인하대학교 산학협력단 | 미세 액적 제조장치 |
EP3978134A1 (de) * | 2017-07-05 | 2022-04-06 | miDiagnostics NV | Anordnung in einem kapillaren angetriebenen mikrofluidischen system zum auflösen eines reagens in einem fluid |
CN111135881B (zh) * | 2019-12-19 | 2021-03-19 | 清华大学 | 基于液-液层流界面分子扩散层内物质相互作用的化学笔 |
CN113522192B (zh) * | 2020-04-20 | 2022-10-21 | 中国石油化工股份有限公司 | 制备聚α-烯烃的装置和方法 |
CN113797986B (zh) * | 2021-10-11 | 2023-05-26 | 苏州美翎生物医学科技有限公司 | 一种可微调毛细管同轴排列的微流控芯片 |
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AU4910300A (en) | 1999-04-08 | 2000-11-14 | Bernd Penth | Method and device for carrying out chemical and physical processes |
US6453928B1 (en) * | 2001-01-08 | 2002-09-24 | Nanolab Ltd. | Apparatus, and method for propelling fluids |
-
2000
- 2000-03-02 GB GB0004958A patent/GB2359765B/en not_active Expired - Lifetime
-
2001
- 2001-03-01 AU AU2001235792A patent/AU2001235792A1/en not_active Abandoned
- 2001-03-01 US US10/220,785 patent/US7032607B2/en not_active Expired - Lifetime
- 2001-03-01 DE DE60103249T patent/DE60103249T2/de not_active Expired - Lifetime
- 2001-03-01 EP EP01907926A patent/EP1259316B1/de not_active Expired - Lifetime
- 2001-03-01 WO PCT/GB2001/000848 patent/WO2001064332A1/en active IP Right Grant
- 2001-03-01 JP JP2001563223A patent/JP2003525116A/ja active Pending
- 2001-03-01 AT AT01907926T patent/ATE266466T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2359765A (en) | 2001-09-05 |
DE60103249T2 (de) | 2005-05-25 |
WO2001064332A1 (en) | 2001-09-07 |
EP1259316A1 (de) | 2002-11-27 |
JP2003525116A (ja) | 2003-08-26 |
GB2359765B (en) | 2003-03-05 |
US20030145894A1 (en) | 2003-08-07 |
GB0004958D0 (en) | 2000-04-19 |
EP1259316B1 (de) | 2004-05-12 |
ATE266466T1 (de) | 2004-05-15 |
US7032607B2 (en) | 2006-04-25 |
AU2001235792A1 (en) | 2001-09-12 |
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