DE60101468D1 - Direktkomprimierte partikel für feste darreichungsformen - Google Patents
Direktkomprimierte partikel für feste darreichungsformenInfo
- Publication number
- DE60101468D1 DE60101468D1 DE60101468T DE60101468T DE60101468D1 DE 60101468 D1 DE60101468 D1 DE 60101468D1 DE 60101468 T DE60101468 T DE 60101468T DE 60101468 T DE60101468 T DE 60101468T DE 60101468 D1 DE60101468 D1 DE 60101468D1
- Authority
- DE
- Germany
- Prior art keywords
- directly compressed
- pharmaceutical forms
- compressed particles
- copolymer
- fixed pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US559687 | 2000-04-27 | ||
US09/559,687 US6623756B1 (en) | 2000-04-27 | 2000-04-27 | Directly compressed solid dosage articles |
PCT/US2001/012400 WO2001082894A2 (en) | 2000-04-27 | 2001-04-17 | Directly compressed solid dosage particles |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60101468D1 true DE60101468D1 (de) | 2004-01-22 |
DE60101468T2 DE60101468T2 (de) | 2004-10-28 |
Family
ID=24234605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60101468T Expired - Lifetime DE60101468T2 (de) | 2000-04-27 | 2001-04-17 | Direktkomprimierte partikel für feste darreichungsformen |
Country Status (13)
Country | Link |
---|---|
US (1) | US6623756B1 (de) |
EP (1) | EP1276466B1 (de) |
JP (1) | JP2003531848A (de) |
CN (1) | CN1195498C (de) |
AT (1) | ATE255886T1 (de) |
BR (1) | BR0110287A (de) |
CA (1) | CA2407140A1 (de) |
DE (1) | DE60101468T2 (de) |
ES (1) | ES2211796T3 (de) |
IL (2) | IL152461A0 (de) |
MX (1) | MXPA02010437A (de) |
WO (1) | WO2001082894A2 (de) |
ZA (1) | ZA200208571B (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7985420B2 (en) * | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US8012504B2 (en) * | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
US7838032B2 (en) * | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
US6955821B2 (en) | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
US6623754B2 (en) * | 2001-05-21 | 2003-09-23 | Noveon Ip Holdings Corp. | Dosage form of N-acetyl cysteine |
US20030012820A1 (en) * | 2001-06-12 | 2003-01-16 | Upadhyay Ajay Hasmukhlal | Compressible guaifenesin compositions, method for making same and method for making compressed guaifenesin dosage forms therefrom |
US6705028B2 (en) * | 2001-09-12 | 2004-03-16 | Honda Giken Kogyo Kabushiki Kaisha | Self-propelled snowplow vehicle |
US20040185016A1 (en) * | 2002-07-30 | 2004-09-23 | Popp Karl F | Compositions for treatment of hyperpigmentation and methods for making and using such compositions |
US20040219210A1 (en) * | 2003-05-01 | 2004-11-04 | Jian-Hwa Guo | Controlled release solid dosage nifedipine formulations |
US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
US7704522B2 (en) * | 2004-09-08 | 2010-04-27 | Clyde Morgan | Topical medicament |
US20070077297A1 (en) * | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
FI20080346A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi lisäaineita sisältävän tabletin valmistamiseksi |
FI20080355A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi metforminia käsittävien tablettien valmistamiseksi |
FI20080353A0 (fi) * | 2008-05-09 | 2008-05-09 | Atacama Labs Oy | Prosessi erittäin korkean lääkepitoisuuden tabletin valmistamiseksi |
US7749537B2 (en) * | 2006-12-04 | 2010-07-06 | Scolr Pharma, Inc. | Method of forming a tablet |
CN101467988B (zh) * | 2007-12-27 | 2014-07-09 | 北京德众万全医药科技有限公司 | 一种含有氨酚伪麻的药用组合物及其制备方法 |
EP2379993A1 (de) * | 2008-12-17 | 2011-10-26 | AstraZeneca AB | Verfahren zur ausgabe einer zieldosis, pulverausgabegerät und seine verwendung |
TW201117812A (en) | 2009-08-05 | 2011-06-01 | Idenix Pharmaceuticals Inc | Macrocyclic serine protease inhibitors |
WO2011056764A1 (en) | 2009-11-05 | 2011-05-12 | Ambit Biosciences Corp. | Isotopically enriched or fluorinated imidazo[2,1-b][1,3]benzothiazoles |
RU2554087C2 (ru) | 2009-12-18 | 2015-06-27 | Айденикс Фармасьютикалз, Инк. | 5,5-конденсированные ариленовые или гетероариленовые ингибиторы вируса гепатита с |
WO2011094890A1 (en) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators |
WO2011112689A2 (en) | 2010-03-11 | 2011-09-15 | Ambit Biosciences Corp. | Saltz of an indazolylpyrrolotriazine |
ES2581840T3 (es) | 2010-09-01 | 2016-09-07 | Ambit Biosciences Corporation | Pirazolilaminoquinazolina ópticamente activa y composiciones farmacéuticas y métodos de uso de la misma |
AU2011296046B2 (en) | 2010-09-01 | 2015-05-14 | Ambit Biosciences Corporation | Hydrobromide salts of a pyrazolylaminoquinazoline |
WO2012078649A1 (en) | 2010-12-06 | 2012-06-14 | Follica, Inc. | Methods for treating baldness and promoting hair growth |
WO2012080050A1 (en) | 2010-12-14 | 2012-06-21 | F. Hoffmann-La Roche Ag | Solid forms of a phenoxybenzenesulfonyl compound |
CA2825152A1 (en) | 2011-01-31 | 2012-08-09 | Celgene Corporation | Pharmaceutical compositions of cytidine analogs and methods of use thereof |
AR085352A1 (es) | 2011-02-10 | 2013-09-25 | Idenix Pharmaceuticals Inc | Inhibidores macrociclicos de serina proteasa, sus composiciones farmaceuticas y su uso para tratar infecciones por hcv |
US20120252721A1 (en) | 2011-03-31 | 2012-10-04 | Idenix Pharmaceuticals, Inc. | Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor |
EP2852586A1 (de) | 2012-03-16 | 2015-04-01 | Axikin Pharmaceuticals, Inc. | 3,5-diaminopyrazol-kinaseinhibitoren |
NZ631142A (en) | 2013-09-18 | 2016-03-31 | Axikin Pharmaceuticals Inc | Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors |
EP3046924A1 (de) | 2013-09-20 | 2016-07-27 | IDENIX Pharmaceuticals, Inc. | Inhibitoren des hepatitis-c-virus |
WO2015134560A1 (en) | 2014-03-05 | 2015-09-11 | Idenix Pharmaceuticals, Inc. | Solid forms of a flaviviridae virus inhibitor compound and salts thereof |
US10202398B2 (en) | 2014-03-20 | 2019-02-12 | Capella Therapeutics, Inc. | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer |
MX2016012097A (es) | 2014-03-20 | 2017-04-27 | Capella Therapeutics Inc | Derivados de bencimidazol como inhibidores de tirosina cinasa erbb para el tratamiento del cáncer. |
MY191736A (en) | 2014-12-23 | 2022-07-13 | Axikin Pharmaceuticals Inc | 3,5-diaminopyrazole kinase inhibitors |
US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
CN113329810A (zh) | 2019-01-24 | 2021-08-31 | 诺和诺德股份有限公司 | 辊压机和使用辊压机的干法制粒方法 |
EP4025353A1 (de) | 2019-09-06 | 2022-07-13 | Novo Nordisk A/S | Verfahren und vorrichtung zur fraktionierung von granulaten zur verwendung in pharmazeutischen zusammensetzungen |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2798053A (en) * | 1952-09-03 | 1957-07-02 | Goodrich Co B F | Carboxylic polymers |
US3915921A (en) * | 1974-07-02 | 1975-10-28 | Goodrich Co B F | Unsaturated carboxylic acid-long chain alkyl ester copolymers and tri-polymers water thickening agents and emulsifiers |
US4267103A (en) * | 1978-12-07 | 1981-05-12 | The B. F. Goodrich Company | Solvent polymerization of carboxyl containing monomers |
DE3888520T2 (de) * | 1988-03-30 | 1994-07-21 | Japan Synthetic Rubber Co Ltd | Hoch vernetzte Polymerteilchen und Verfahren zur Herstellung derselben. |
EP0643737B1 (de) * | 1992-05-09 | 2001-11-21 | Surfachem Group Limited | Umwandlung von pulverförmigen polymeren |
US5288814A (en) * | 1992-08-26 | 1994-02-22 | The B. F. Goodrich Company | Easy to disperse polycarboxylic acid thickeners |
US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
-
2000
- 2000-04-27 US US09/559,687 patent/US6623756B1/en not_active Expired - Fee Related
-
2001
- 2001-04-17 AT AT01925043T patent/ATE255886T1/de not_active IP Right Cessation
- 2001-04-17 CA CA002407140A patent/CA2407140A1/en not_active Abandoned
- 2001-04-17 CN CNB018086330A patent/CN1195498C/zh not_active Expired - Fee Related
- 2001-04-17 WO PCT/US2001/012400 patent/WO2001082894A2/en active IP Right Grant
- 2001-04-17 IL IL15246101A patent/IL152461A0/xx active IP Right Grant
- 2001-04-17 JP JP2001579769A patent/JP2003531848A/ja not_active Withdrawn
- 2001-04-17 MX MXPA02010437A patent/MXPA02010437A/es active IP Right Grant
- 2001-04-17 EP EP01925043A patent/EP1276466B1/de not_active Expired - Lifetime
- 2001-04-17 DE DE60101468T patent/DE60101468T2/de not_active Expired - Lifetime
- 2001-04-17 ES ES01925043T patent/ES2211796T3/es not_active Expired - Lifetime
- 2001-04-17 BR BR0110287-7A patent/BR0110287A/pt not_active Application Discontinuation
-
2002
- 2002-10-23 ZA ZA200208571A patent/ZA200208571B/en unknown
- 2002-10-24 IL IL152461A patent/IL152461A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1276466A2 (de) | 2003-01-22 |
ATE255886T1 (de) | 2003-12-15 |
CN1195498C (zh) | 2005-04-06 |
BR0110287A (pt) | 2003-02-18 |
ES2211796T3 (es) | 2004-07-16 |
CN1426297A (zh) | 2003-06-25 |
US6623756B1 (en) | 2003-09-23 |
DE60101468T2 (de) | 2004-10-28 |
JP2003531848A (ja) | 2003-10-28 |
WO2001082894A2 (en) | 2001-11-08 |
EP1276466B1 (de) | 2003-12-10 |
ZA200208571B (en) | 2003-08-19 |
IL152461A0 (en) | 2003-05-29 |
IL152461A (en) | 2007-08-19 |
WO2001082894A3 (en) | 2002-02-21 |
MXPA02010437A (es) | 2003-04-25 |
CA2407140A1 (en) | 2001-11-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee | ||
8370 | Indication related to discontinuation of the patent is to be deleted | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: LUBRIZOL ADVANCED MATERIALS, INC., CLEVELAND, , US |