DE60044005D1 - 85 kDa Antigen von Neisseria - Google Patents

85 kDa Antigen von Neisseria

Info

Publication number
DE60044005D1
DE60044005D1 DE60044005T DE60044005T DE60044005D1 DE 60044005 D1 DE60044005 D1 DE 60044005D1 DE 60044005 T DE60044005 T DE 60044005T DE 60044005 T DE60044005 T DE 60044005T DE 60044005 D1 DE60044005 D1 DE 60044005D1
Authority
DE
Germany
Prior art keywords
neisseria
gonorrhoeae
meningitidis
antigen
kda antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044005T
Other languages
English (en)
Inventor
Marzia Monica Giuliani
Mariagrazia Pizza
Rino Rappuoli
Johan Holst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines SRL
Statens Institutt for Folkehelse
Original Assignee
Novartis Vaccines and Diagnostics SRL
Statens Institutt for Folkehelse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9928197.4A external-priority patent/GB9928197D0/en
Priority claimed from GB0005698A external-priority patent/GB0005698D0/en
Application filed by Novartis Vaccines and Diagnostics SRL, Statens Institutt for Folkehelse filed Critical Novartis Vaccines and Diagnostics SRL
Application granted granted Critical
Publication of DE60044005D1 publication Critical patent/DE60044005D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE60044005T 1999-11-29 2000-11-28 85 kDa Antigen von Neisseria Expired - Lifetime DE60044005D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9928197.4A GB9928197D0 (en) 1999-11-29 1999-11-29 85kDA antigen
GB0005698A GB0005698D0 (en) 2000-03-09 2000-03-09 85kDa Antigen

Publications (1)

Publication Number Publication Date
DE60044005D1 true DE60044005D1 (de) 2010-04-22

Family

ID=26243826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044005T Expired - Lifetime DE60044005D1 (de) 1999-11-29 2000-11-28 85 kDa Antigen von Neisseria

Country Status (13)

Country Link
US (1) US7700119B2 (de)
EP (2) EP1741784B1 (de)
JP (2) JP4840956B2 (de)
CN (1) CN1433471A (de)
AT (1) ATE460484T1 (de)
AU (1) AU1875301A (de)
BR (1) BR0015961A (de)
CA (1) CA2390344C (de)
CY (1) CY1110540T1 (de)
DE (1) DE60044005D1 (de)
DK (1) DK1741784T3 (de)
RU (1) RU2002117308A (de)
WO (1) WO2001038350A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2266656A1 (en) 1996-09-17 1998-03-26 Chiron Corporation Compositions and methods for treating intracellular diseases
DE60126249T2 (de) * 2000-02-28 2008-05-29 Novartis Vaccines And Diagnostics S.R.L. Heterologe expression von neisseria-proteinen
EP1412381B1 (de) 2001-07-27 2010-06-02 Novartis Vaccines and Diagnostics S.r.l. Antikörper gegen das meningokokken adhäsin app
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
EP1524993B1 (de) 2002-08-02 2013-03-06 GlaxoSmithKline Biologicals s.a. Neisseria impfstoffzusammensetzungen die eine kombination von antigenen enthalten
AU2003274511B2 (en) * 2002-10-11 2009-06-04 Glaxosmithkline Biologicals S.A. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
CA2506318C (en) 2002-11-15 2011-07-12 Chiron Srl Unexpected surface proteins in neisseria meningitidis
GB0408977D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
US9148335B2 (en) * 2008-09-30 2015-09-29 Qualcomm Incorporated Third party validation of internet protocol addresses
BRPI0923006A2 (pt) 2008-12-17 2016-03-08 Novartis Ag vacinas meningococicas incluindo receptor de hemoglobina
PL2411048T3 (pl) 2009-03-24 2020-11-16 Glaxosmithkline Biologicals Sa Adjuwantowe meningokokowe białko wiążące czynnik h
EP2411045A1 (de) 2009-03-24 2012-02-01 Novartis AG Kombinationen aus meningokokken-faktor-h-bindungsprotein und pneumokokken-saccharid-konjugaten
CN102596240B (zh) 2009-08-27 2015-02-04 诺华股份有限公司 包括脑膜炎球菌fHBP序列的杂交多肽
CN102740882A (zh) 2009-08-27 2012-10-17 诺华有限公司 含有铝、寡核苷酸和聚阳离子的佐剂
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
BR112012010531A2 (pt) 2009-10-27 2019-09-24 Novartis Ag "polipeptídeos de modificação meningocócica fhbp"
US20130071422A1 (en) 2010-03-18 2013-03-21 Michele Pallaoro Adjuvanted vaccines for serogroup b meningococcus
AU2011268507B2 (en) 2010-06-25 2014-08-14 Novartis Ag Combinations of meningococcal factor H binding proteins
PT3246044T (pt) 2010-08-23 2021-02-15 Wyeth Llc Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis
BR112013005626B1 (pt) 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
MX362802B (es) 2010-09-10 2019-02-13 Wyeth Llc Star Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis.
EP2707009A1 (de) 2011-05-12 2014-03-19 Novartis AG Antipyretika zur verbesserung der verträglichkeit von impfstoffen auf vesikelbasis
US10596246B2 (en) 2011-12-29 2020-03-24 Glaxosmithkline Biological Sa Adjuvanted combinations of meningococcal factor H binding proteins
MX2014008988A (es) 2012-02-02 2014-08-27 Novartis Ag Promotores para aumento de expresion de proteinas en meningococo.
US10598666B2 (en) 2012-03-08 2020-03-24 Glaxosmithkline Biologicals Sa In vitro potency assay for protein-based meningococcal vaccines
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
JP6446377B2 (ja) 2013-03-08 2018-12-26 ファイザー・インク 免疫原性融合ポリペプチド
MX369534B (es) 2013-09-08 2019-11-11 Pfizer Composiciones de neisseria meningitidis y sus metodos.
LT3110442T (lt) 2014-02-28 2020-12-28 Glaxosmithkline Biologicals Sa Modifikuoti meningokokinio fhbp polipeptidai
RU2723045C2 (ru) 2015-02-19 2020-06-08 Пфайзер Инк. Композиции neisseria meningitidis и способы их получения
US10183070B2 (en) 2017-01-31 2019-01-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
GB202115077D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Assay

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3436756B2 (ja) * 1988-12-19 2003-08-18 アメリカン・サイアナミド・カンパニー 髄膜炎菌のクラスｉの外膜タンパク質のワクチン
GB9313045D0 (en) 1993-06-24 1993-08-11 Source Vision Technology The L Printing and laminating
US5439808A (en) 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
IL117483A (en) 1995-03-17 2008-03-20 Bernard Brodeur MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
IL125420A0 (en) * 1996-02-01 1999-03-12 North American Vaccine Inc Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines containing said protein
EP1900818A3 (de) 1997-11-06 2008-06-11 Novartis Vaccines and Diagnostics S.r.l. Neissersche Antigene
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
JP4399112B2 (ja) 1998-01-14 2010-01-13 カイロン ソチエタ ア レスポンサビリタ リミタータ ＮｅｉｓｓｅｒｉａＭｅｎｉｎｇｉｔｉｄｉｓ抗原
US7576176B1 (en) 1998-05-01 2009-08-18 Novartis Vaccines And Diagnostics, Inc. Neisseria meningitidis antigens and compositions
EP1144998A3 (de) * 1998-10-09 2002-08-07 Chiron Corporation Genomische sequenzen von neisseria und verfahren zu ihrer verwendung
EP1123403A1 (de) * 1998-10-22 2001-08-16 The University Of Montana Omp85 proteine von neisseria gonorrhoeae uand neisseria meningitidis, zusammensetzungen die sie enthalten und verfahren zur anwendung davon
US6610306B2 (en) * 1998-10-22 2003-08-26 The University Of Montana OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof
US8221761B1 (en) * 1999-02-26 2012-07-17 Novartis Ag Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing CG motifs

Also Published As

Publication number Publication date
ATE460484T1 (de) 2010-03-15
EP1234039A2 (de) 2002-08-28
JP4840956B2 (ja) 2011-12-21
CA2390344C (en) 2014-08-26
EP1741784A1 (de) 2007-01-10
JP2011055838A (ja) 2011-03-24
RU2002117308A (ru) 2004-03-10
BR0015961A (pt) 2003-06-10
CA2390344A1 (en) 2001-05-31
US7700119B2 (en) 2010-04-20
CY1110540T1 (el) 2015-04-29
DK1741784T3 (da) 2010-05-25
JP2003514575A (ja) 2003-04-22
EP1741784B1 (de) 2010-03-10
WO2001038350A2 (en) 2001-05-31
CN1433471A (zh) 2003-07-30
US20060233827A1 (en) 2006-10-19
AU1875301A (en) 2001-06-04
WO2001038350A3 (en) 2001-11-15

Similar Documents

Publication Publication Date Title
DE60044005D1 (de) 85 kDa Antigen von Neisseria
WO2000066741A3 (en) Conserved neisserial antigens
CY1110880T1 (el) Αντιγονα neisserial
NZ515935A (en) Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis
BR9906927A (pt) Proteìnas de neisseria meningitidis
BR9910089A (pt) Composições e antìgenos de neisseria meningitidis
WO1998056901A3 (en) Live attenuated vaccines
GEP20032977B (en) Proteinase K-Resistant Surface Protein of Neisseria Meningitidis
PT1235589E (pt) Composições compreendendo antigénios da neisseria meningitidis dos serogrupos b e c, e outro antigénio
BR0108711A (pt) Expressão heteróloga de proteìnas de neisseria
CY1106875T1 (el) Αντιγονικα πεπτιδια απο neisseria
ATE505478T1 (de) Molekular-mimetika von meningokokkalen b epitopen
MX339524B (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
PT1154790E (pt) Reforco da actividade bactericida de antigenios contra a neisseria com oligonucleotidos contendo motivos cg
WO2001004316A3 (en) Antigenic meningococcal peptides
DE60038099D1 (de) Neisseria impfstoffzusammensetzungen und methoden
ATE401341T1 (de) Vakzine enthaltend omp85 proteine von neisseria gonorrhoeae und neisseria meningitidis
WO2004093903A3 (en) Methods and compositions for immunomodulation using cd1 antigens
RU94022337A (ru) Штамм бактерий proteus mirabilis - продуцент термолабильного энтеротоксина

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R082 Change of representative

Ref document number: 1741784

Country of ref document: EP

Representative=s name: UEXKUELL & STOLBERG, 22607 HAMBURG, DE