DE60041540D1 - Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren - Google Patents

Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren

Info

Publication number
DE60041540D1
DE60041540D1 DE60041540T DE60041540T DE60041540D1 DE 60041540 D1 DE60041540 D1 DE 60041540D1 DE 60041540 T DE60041540 T DE 60041540T DE 60041540 T DE60041540 T DE 60041540T DE 60041540 D1 DE60041540 D1 DE 60041540D1
Authority
DE
Germany
Prior art keywords
organisms
cultivation
micro
manufacture
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60041540T
Other languages
English (en)
Inventor
Colin Ratledge
Alistair James Anderson
Kanagasooriyam Kanagachandran
David John Grantham
Janet Christine Stephenson
Swaaf Martin E De
Lolke Sijtsma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hull
Ato BV
Original Assignee
University of Hull
Ato BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hull, Ato BV filed Critical University of Hull
Application granted granted Critical
Publication of DE60041540D1 publication Critical patent/DE60041540D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE60041540T 1999-07-14 2000-07-13 Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren Expired - Fee Related DE60041540D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9916537.5A GB9916537D0 (en) 1999-07-14 1999-07-14 Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
PCT/GB2000/002695 WO2001004338A1 (en) 1999-07-14 2000-07-13 Culture of crypthecodinium cohnii for the synthesis of a polyunsaturated fatty acid

Publications (1)

Publication Number Publication Date
DE60041540D1 true DE60041540D1 (de) 2009-03-26

Family

ID=10857245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60041540T Expired - Fee Related DE60041540D1 (de) 1999-07-14 2000-07-13 Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren

Country Status (7)

Country Link
US (2) US6977166B1 (de)
EP (1) EP1194583B1 (de)
AT (1) ATE422551T1 (de)
DE (1) DE60041540D1 (de)
GB (2) GB9916537D0 (de)
NO (1) NO326280B1 (de)
WO (1) WO2001004338A1 (de)

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GB9916537D0 (en) 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
GB2377455A (en) * 2001-02-09 2003-01-15 Univ Hull Method of culturing crypthecodinium cohnii
EP1359224A1 (de) * 2002-05-01 2003-11-05 Ato B.V. Verfahren zur Herstellung von mehrfach ungesättigten Fettsäuren durch marine Mikroorganismen
JP4733043B2 (ja) 2003-10-02 2011-07-27 マーテック バイオサイエンシーズ コーポレーション 改変された量の塩化物およびカリウムを使用した微細藻類における高レベルのｄｈａの産生法
CA2715018C (en) 2008-03-20 2012-11-13 Virun, Inc. Vitamin e derivatives and their uses
DK2268160T3 (da) 2008-03-20 2013-01-07 Virun Inc Emulsioner omfattende et PEG-derivat af tokoferol
CN102131407B (zh) * 2008-06-23 2015-01-07 维尔恩公司 含有非极性化合物的组合物
CN103037708B (zh) 2010-03-23 2015-05-20 维尔恩公司 含有蔗糖脂肪酸酯的纳米乳液
WO2011162802A1 (en) 2010-06-21 2011-12-29 Virun, Inc. Compositions containing non-polar compounds
CN101979623B (zh) * 2010-10-09 2012-07-04 南京工业大学 外源添加因子促进微生物合成二十二碳六烯酸的方法
US10874122B2 (en) 2012-02-10 2020-12-29 Virun, Inc. Beverage compositions containing non-polar compounds
JP6349322B2 (ja) * 2012-11-09 2018-06-27 ヘリアエ デベロップメント、 エルエルシー 非純粋培養混合栄養条件下で微生物を培養する方法
WO2014074770A2 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Balanced mixotrophy methods
WO2014074772A1 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Mixotrophic, phototrophic, and heterotrophic combination methods and systems
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
JP6134049B2 (ja) 2013-03-15 2017-05-24 バイラン・インコーポレイテッドＶｉｒｕｎ，Ｉｎｃ． ビタミンｅの水溶性誘導体の製品およびそれを含む組成物
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
CN104017846B (zh) * 2014-06-04 2016-09-28 中国科学院等离子体物理研究所 一种利用寇式隐甲藻atcc30772发酵废弃菌渣制备高产量纳他霉素的方法
MX2017002003A (es) 2014-08-14 2017-11-22 Change Nutrition Inc Bebida carbonatada que comprende omega, vitaminas y minerales.
FR3025215A1 (fr) 2014-08-27 2016-03-04 Fermentalg Nouveau procede de culture de microalgues
WO2016044805A1 (en) 2014-09-18 2016-03-24 Virun, Inc. Soft gel compositions and pre-gel concentrates
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
CN105670771A (zh) * 2016-02-26 2016-06-15 深圳市荣格保健品有限公司 一种藻油dha提取制备方法
CN106010970B (zh) * 2016-07-13 2019-07-26 中国科学院青岛生物能源与过程研究所 一种寇氏隐甲藻及其应用

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Publication number Priority date Publication date Assignee Title
US3444647A (en) 1961-08-08 1969-05-20 Masahito Takahashi Process of cultivating algae
KR890701751A (ko) 1987-07-20 1989-12-21 원본 미기재 오메가-3(n-3) 지질의 미생물 생성물
JPS6440433A (en) * 1987-08-05 1989-02-10 Green Cross Corp Aqueous liquid composition of thrombin
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5244921A (en) 1990-03-21 1993-09-14 Martek Corporation Eicosapentaenoic acids and methods for their production
ZA92452B (en) 1991-01-24 1992-10-28 Martek Corp Microbial oil mixtures and uses thereof
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
AU3091392A (en) 1991-12-11 1993-07-19 Sasol Chemicals Europe Limited Method to produce single cell oil containing gamma-linolenic acid
JPH078215A (ja) * 1993-04-30 1995-01-13 Kawasaki Steel Corp ドコサヘキサエン酸含有海洋性微細藻類食品素材およびその製造方法
JPH0787988A (ja) 1993-09-21 1995-04-04 Kawasaki Steel Corp 海洋性微細藻類の培養方法
EP1886679A3 (de) 1995-06-07 2008-05-28 Martek Biosciences Corporation Verfahren zur Regulierung des Gehalts an mehrfach ungesättigten Fettsäuren in verschiedenen Geweben
JP4545235B2 (ja) * 1996-03-28 2010-09-15 ディーエスエム アイピー アセッツ ビー．ブイ． 顆粒状微生物バイオマスの製造法とそのバイオマスからの貴重化合物の単離法
WO1999006585A1 (en) 1997-08-01 1999-02-11 Martek Biosciences Corporation Dha-containing nutritional compositions and methods for their production
WO2000054575A2 (en) 1999-03-16 2000-09-21 Martek Biosciences Corporation Infant formulas and other food products containing phospholipids
GB9916537D0 (en) 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
AU2634101A (en) 2000-01-06 2001-07-16 Martek Biosciences Corporation Therapeutic preparations of highly unsaturated fatty acids
GB2377455A (en) * 2001-02-09 2003-01-15 Univ Hull Method of culturing crypthecodinium cohnii

Also Published As

Publication number Publication date
GB2372752A (en) 2002-09-04
GB2372752B (en) 2004-06-23
US6977166B1 (en) 2005-12-20
NO20020149L (no) 2002-03-12
ATE422551T1 (de) 2009-02-15
EP1194583B1 (de) 2009-02-11
US20050250190A1 (en) 2005-11-10
NO20020149D0 (no) 2002-01-11
NO326280B1 (no) 2008-11-03
GB9916537D0 (en) 1999-09-15
EP1194583A1 (de) 2002-04-10
GB0201283D0 (en) 2002-03-06
WO2001004338A1 (en) 2001-01-18

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