DE60041540D1 - Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren - Google Patents

Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren

Info

Publication number
DE60041540D1
DE60041540D1 DE60041540T DE60041540T DE60041540D1 DE 60041540 D1 DE60041540 D1 DE 60041540D1 DE 60041540 T DE60041540 T DE 60041540T DE 60041540 T DE60041540 T DE 60041540T DE 60041540 D1 DE60041540 D1 DE 60041540D1
Authority
DE
Germany
Prior art keywords
organisms
cultivation
micro
manufacture
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60041540T
Other languages
English (en)
Inventor
Colin Ratledge
Alistair James Anderson
Kanagasooriyam Kanagachandran
David John Grantham
Janet Christine Stephenson
Swaaf Martin E De
Lolke Sijtsma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hull
Ato BV
Original Assignee
University of Hull
Ato BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hull, Ato BV filed Critical University of Hull
Application granted granted Critical
Publication of DE60041540D1 publication Critical patent/DE60041540D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C12N1/125—Unicellular algae isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/89—Algae ; Processes using algae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60041540T 1999-07-14 2000-07-13 Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren Expired - Fee Related DE60041540D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9916537.5A GB9916537D0 (en) 1999-07-14 1999-07-14 Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
PCT/GB2000/002695 WO2001004338A1 (en) 1999-07-14 2000-07-13 Culture of crypthecodinium cohnii for the synthesis of a polyunsaturated fatty acid

Publications (1)

Publication Number Publication Date
DE60041540D1 true DE60041540D1 (de) 2009-03-26

Family

ID=10857245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60041540T Expired - Fee Related DE60041540D1 (de) 1999-07-14 2000-07-13 Kultivierung von mikroorganismen zur herstellung von mehrfach-ungesättigten fettsäuren

Country Status (7)

Country Link
US (2) US6977166B1 (de)
EP (1) EP1194583B1 (de)
AT (1) ATE422551T1 (de)
DE (1) DE60041540D1 (de)
GB (2) GB9916537D0 (de)
NO (1) NO326280B1 (de)
WO (1) WO2001004338A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9916537D0 (en) 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
GB2377455A (en) * 2001-02-09 2003-01-15 Univ Hull Method of culturing crypthecodinium cohnii
EP1359224A1 (de) * 2002-05-01 2003-11-05 Ato B.V. Verfahren zur Herstellung von mehrfach ungesättigten Fettsäuren durch marine Mikroorganismen
EP1702073B1 (de) * 2003-10-02 2014-01-01 DSM IP Assets B.V. Produktion hoher dha-niveaus in mikroalgen unter verwendung modifizierter mengen an chlorid und kalium
EP2268274B1 (de) 2008-03-20 2012-05-16 Virun, Inc. Vitamin-e-derivate und ihre verwendungen
MX2010010050A (es) 2008-03-20 2011-03-15 Virun Inc Star Emulsiones que incluyen un derivado de polietilen glicol de tocoferol.
US8337931B2 (en) * 2008-06-23 2012-12-25 Virun, Inc. Compositions containing non-polar compounds
EP2563164B1 (de) 2010-03-23 2016-06-29 Virun, Inc. Nanoemulsionen enthaltend saccharosefettsäureester
US8741373B2 (en) 2010-06-21 2014-06-03 Virun, Inc. Compositions containing non-polar compounds
CN101979623B (zh) * 2010-10-09 2012-07-04 南京工业大学 外源添加因子促进微生物合成二十二碳六烯酸的方法
SG11201404640YA (en) 2012-02-10 2014-09-26 Virun Inc Beverage compositions containing non-polar compounds
WO2014074770A2 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Balanced mixotrophy methods
CA2888493C (en) * 2012-11-09 2022-06-07 Heliae Development, Llc Methods of culturing microorganisms in non-axenic mixotrophic conditions
WO2014074772A1 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Mixotrophic, phototrophic, and heterotrophic combination methods and systems
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
WO2014151109A1 (en) 2013-03-15 2014-09-25 Virun, Inc. Formulations of water-soluble derivatives of vitamin e and compositions containing same
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
CN104017846B (zh) * 2014-06-04 2016-09-28 中国科学院等离子体物理研究所 一种利用寇式隐甲藻atcc30772发酵废弃菌渣制备高产量纳他霉素的方法
AU2015301478A1 (en) 2014-08-14 2017-03-09 Change Cola, Inc. Carbonated drink comprising omega, vitamins and minerals
FR3025215A1 (fr) 2014-08-27 2016-03-04 Fermentalg Nouveau procede de culture de microalgues
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
WO2016044805A1 (en) 2014-09-18 2016-03-24 Virun, Inc. Soft gel compositions and pre-gel concentrates
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
CN105670771A (zh) * 2016-02-26 2016-06-15 深圳市荣格保健品有限公司 一种藻油dha提取制备方法
CN106010970B (zh) * 2016-07-13 2019-07-26 中国科学院青岛生物能源与过程研究所 一种寇氏隐甲藻及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444647A (en) 1961-08-08 1969-05-20 Masahito Takahashi Process of cultivating algae
WO1989000606A1 (en) 1987-07-20 1989-01-26 Maricultura, Incorporated Microorganism production of omega-3 (n-3) lipids
JPS6440433A (en) * 1987-08-05 1989-02-10 Green Cross Corp Aqueous liquid composition of thrombin
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US5244921A (en) 1990-03-21 1993-09-14 Martek Corporation Eicosapentaenoic acids and methods for their production
ZA92452B (en) 1991-01-24 1992-10-28 Martek Corp Microbial oil mixtures and uses thereof
US5658767A (en) 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
DE69226374T2 (de) 1991-12-11 1999-04-15 Sastech Pty Ltd Verfahren zur herstellung eines gamma-linolensäure enthaltenden einzell-öls
JPH078215A (ja) * 1993-04-30 1995-01-13 Kawasaki Steel Corp ドコサヘキサエン酸含有海洋性微細藻類食品素材およびその製造方法
JPH0787988A (ja) 1993-09-21 1995-04-04 Kawasaki Steel Corp 海洋性微細藻類の培養方法
EP0831805A1 (de) 1995-06-07 1998-04-01 Martek Biosciences Corporation Verfahren zur kontrolle des hochungesättigten-fettsäuren gehalts in verschiedenen geweben
CN1226923B (zh) * 1996-03-28 2011-06-15 Dsmip资产有限公司 粒状微生物生物量的制备及其有价值的化合物的分离方法
DE69831674T2 (de) 1997-08-01 2006-06-22 Martek Biosciences Corp. Dha-enthaltende naehrzusammensetzungen und verfahren zu deren herstellung
AU3884500A (en) 1999-03-16 2000-10-04 Martek Biosciences Corporation Infant formulas and other food products containing phospholipids
GB9916537D0 (en) 1999-07-14 1999-09-15 Univ Hull Culture of microorganisms for the synthesis of a polyunsaturated fatty acid
AU2634101A (en) 2000-01-06 2001-07-16 Martek Biosciences Corporation Therapeutic preparations of highly unsaturated fatty acids
GB2377455A (en) * 2001-02-09 2003-01-15 Univ Hull Method of culturing crypthecodinium cohnii

Also Published As

Publication number Publication date
NO20020149D0 (no) 2002-01-11
US6977166B1 (en) 2005-12-20
EP1194583A1 (de) 2002-04-10
NO20020149L (no) 2002-03-12
GB2372752A (en) 2002-09-04
ATE422551T1 (de) 2009-02-15
US20050250190A1 (en) 2005-11-10
GB0201283D0 (en) 2002-03-06
EP1194583B1 (de) 2009-02-11
GB9916537D0 (en) 1999-09-15
GB2372752B (en) 2004-06-23
WO2001004338A1 (en) 2001-01-18
NO326280B1 (no) 2008-11-03

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8339 Ceased/non-payment of the annual fee