DE60040156D1 - Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten - Google Patents
Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamentenInfo
- Publication number
- DE60040156D1 DE60040156D1 DE60040156T DE60040156T DE60040156D1 DE 60040156 D1 DE60040156 D1 DE 60040156D1 DE 60040156 T DE60040156 T DE 60040156T DE 60040156 T DE60040156 T DE 60040156T DE 60040156 D1 DE60040156 D1 DE 60040156D1
- Authority
- DE
- Germany
- Prior art keywords
- electroporation
- gene
- protein
- array
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12981799P | 1999-04-16 | 1999-04-16 | |
PCT/US2000/010337 WO2000062855A1 (en) | 1999-04-16 | 2000-04-17 | Apparatus for electroporation of gene, protein, or drug therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60040156D1 true DE60040156D1 (de) | 2008-10-16 |
Family
ID=22441736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60040156T Expired - Fee Related DE60040156D1 (de) | 1999-04-16 | 2000-04-17 | Vorrichtung zur elektroporation von genen, proteinen oder zur verabreichung von medikamenten |
Country Status (6)
Country | Link |
---|---|
US (1) | US6593130B1 (de) |
EP (1) | EP1210144B1 (de) |
AT (1) | ATE406936T1 (de) |
AU (1) | AU4465600A (de) |
DE (1) | DE60040156D1 (de) |
WO (1) | WO2000062855A1 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8177743B2 (en) | 1998-05-18 | 2012-05-15 | Boston Scientific Scimed, Inc. | Localized delivery of drug agents |
US7729756B2 (en) * | 2000-01-18 | 2010-06-01 | Siemens Aktiengesellschaft | Measurement system for examining a section of tissue on a patient and the use of a measurement system of this type |
JP4310108B2 (ja) * | 2001-04-06 | 2009-08-05 | 中外製薬株式会社 | 脈管系又は尿管を介して遺伝子を導入する方法 |
AU2002220061A1 (en) * | 2001-11-29 | 2003-06-17 | Microlin Llc | Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices |
US7104985B2 (en) * | 2003-03-06 | 2006-09-12 | Martinelli Michael A | Apparatus and method for causing selective necrosis of abnormal cells |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US8802643B1 (en) | 2003-05-30 | 2014-08-12 | University Of South Florida | Method for the treatment of malignancies |
EA200501937A1 (ru) | 2003-05-30 | 2006-08-25 | Университет Южной Флориды | Способ лечения злокачественных опухолей |
US7297786B2 (en) | 2004-07-09 | 2007-11-20 | University Of Iowa Research Foundation | RNA interference in respiratory epitheial cells |
US7729761B2 (en) * | 2004-07-14 | 2010-06-01 | Cardiac Pacemakers, Inc. | Method and apparatus for controlled gene or protein delivery |
US7776373B2 (en) * | 2004-11-19 | 2010-08-17 | Eteka Llc | Apparatus and method for the enhancement of food properties and food prepared therefrom |
US7923251B2 (en) * | 2005-02-23 | 2011-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for avalanche-mediated transfer of agents into cells |
US8101169B2 (en) * | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
JP2008532560A (ja) * | 2005-03-19 | 2008-08-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 微弱電界ネットワークを仲介して行う、生体外で細胞内に遺伝子、タンパク質および薬剤を送達する方法および装置 |
EP1759714A1 (de) * | 2005-09-02 | 2007-03-07 | Bioalliance Pharma | Elektrotransfer von Nukleinsäuren in Gewebezellen |
WO2007117651A2 (en) * | 2006-04-07 | 2007-10-18 | University Of South Florida | Passive electric field focus system for in vivo and in vitro applications |
US20100121253A1 (en) * | 2007-03-14 | 2010-05-13 | The Regents Of The University Of California | Method and Apparatus of Low Strength Electric Field Network-Mediated Delivery of Drug, Gene, SI-RNA, SH-RNA Protein, Peptide, Antibody or Other Biomedical and Therapeutic Molecules and Reagents in Solid Organs |
US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
CA2716985A1 (en) * | 2008-03-06 | 2009-09-11 | Boston Scientific Scimed, Inc. | Balloon catheter devices with sheath covering |
CN101274120B (zh) | 2008-04-29 | 2013-03-13 | 圣太科医疗科技(上海)有限公司 | 生物与医用多路低电压微电场发生仪 |
AU2009244058B2 (en) | 2008-05-09 | 2015-07-02 | Nuvaira, Inc | Systems, assemblies, and methods for treating a bronchial tree |
WO2009140161A1 (en) * | 2008-05-13 | 2009-11-19 | Bio-Rad Laboratories, Inc. | Electroporation of adherent cells with an array of closely spaced electrodes |
WO2010006483A1 (zh) * | 2008-07-18 | 2010-01-21 | 圣太科医疗科技(上海)有限公司 | 微电场网引导的肝脏靶向性细胞内药物传递装置 |
US20110117635A1 (en) * | 2008-07-18 | 2011-05-19 | Luyi Sen | Multipurpose Micro Electric Field Network Cell Processing Device |
US8207138B2 (en) | 2009-05-19 | 2012-06-26 | Medtronic, Inc. | Methods and devices for improved efficiency of RNA delivery to cells |
US20100298697A1 (en) * | 2009-05-19 | 2010-11-25 | Medtronic, Inc. | Method and devices for improved efficiency of rna delivery to cells |
US8932055B2 (en) * | 2009-06-11 | 2015-01-13 | Roberto Armanino | Method employing electric fields to selectively kill microbes in a root canal preparation |
US20120130150A1 (en) | 2009-06-24 | 2012-05-24 | International Scientific Pty Ltd. | apparatus and method of treatment utilizing a varying electromagnetic energization profile |
EP2470232B1 (de) * | 2009-08-27 | 2016-03-30 | Boston Scientific Scimed, Inc. | Ballonkathetervorrichtungen mit wirkstoffbeschichteter schleuse |
WO2011056684A2 (en) | 2009-10-27 | 2011-05-12 | Innovative Pulmonary Solutions, Inc. | Delivery devices with coolable energy emitting assemblies |
WO2011057137A1 (en) | 2009-11-05 | 2011-05-12 | Neuronexus Technologies | Waveguide neural interface device |
US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
AU2010319477A1 (en) | 2009-11-11 | 2012-05-24 | Holaira, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
US20120070829A1 (en) | 2010-09-10 | 2012-03-22 | Bio-Rad Laboratories, Inc. | Size selection of dna for chromatin analysis |
WO2012112606A1 (en) | 2011-02-15 | 2012-08-23 | Bio-Rad Laboratories, Inc. | Detecting methylati0n in a subpopulation of genomic dna |
CN107400711A (zh) | 2011-08-03 | 2017-11-28 | 伯乐实验室公司 | 使用透化处理的细胞过滤小核酸 |
US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
US20210393894A1 (en) * | 2018-01-23 | 2021-12-23 | The Regents Of The University Of California | Downstream delivery of agents in solid organ transplantation |
US10918861B2 (en) * | 2018-07-24 | 2021-02-16 | Wisconsin Alumni Research Foundation | In vivo gene therapy delivery procedure and device |
US20200131500A1 (en) * | 2018-10-26 | 2020-04-30 | Kytopen Corporation | Devices, systems, and kits for electroporation and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236413B1 (en) | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5304120A (en) | 1992-07-01 | 1994-04-19 | Btx Inc. | Electroporation method and apparatus for insertion of drugs and genes into endothelial cells |
US5507724A (en) | 1992-07-01 | 1996-04-16 | Genetronics, Inc. | Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells |
US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
US5634899A (en) * | 1993-08-20 | 1997-06-03 | Cortrak Medical, Inc. | Simultaneous cardiac pacing and local drug delivery method |
US5807306A (en) | 1992-11-09 | 1998-09-15 | Cortrak Medical, Inc. | Polymer matrix drug delivery apparatus |
US5795755A (en) * | 1994-07-05 | 1998-08-18 | Lemelson; Jerome H. | Method of implanting living cells by laser poration at selected sites |
US6041252A (en) * | 1995-06-07 | 2000-03-21 | Ichor Medical Systems Inc. | Drug delivery system and method |
US6090617A (en) * | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
EA002087B1 (ru) | 1997-04-03 | 2001-12-24 | Электрофект Ас | Способ введения фармацевтических препаратов и нуклеиновых кислот в скелетную мышцу |
US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
-
2000
- 2000-04-14 US US09/549,904 patent/US6593130B1/en not_active Expired - Lifetime
- 2000-04-17 WO PCT/US2000/010337 patent/WO2000062855A1/en active Application Filing
- 2000-04-17 EP EP00926064A patent/EP1210144B1/de not_active Expired - Lifetime
- 2000-04-17 AU AU44656/00A patent/AU4465600A/en not_active Abandoned
- 2000-04-17 AT AT00926064T patent/ATE406936T1/de not_active IP Right Cessation
- 2000-04-17 DE DE60040156T patent/DE60040156D1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1210144B1 (de) | 2008-09-03 |
EP1210144A1 (de) | 2002-06-05 |
US6593130B1 (en) | 2003-07-15 |
AU4465600A (en) | 2000-11-02 |
ATE406936T1 (de) | 2008-09-15 |
WO2000062855A1 (en) | 2000-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |