WO2000015120A8 - Iontophoretic drug delivery electrodes - Google Patents

Iontophoretic drug delivery electrodes

Info

Publication number
WO2000015120A8
WO2000015120A8 PCT/US1999/011440 US9911440W WO0015120A8 WO 2000015120 A8 WO2000015120 A8 WO 2000015120A8 US 9911440 W US9911440 W US 9911440W WO 0015120 A8 WO0015120 A8 WO 0015120A8
Authority
WO
WIPO (PCT)
Prior art keywords
medicament
electrode
treatment
dispensing
electrodes
Prior art date
Application number
PCT/US1999/011440
Other languages
French (fr)
Other versions
WO2000015120A1 (en
Inventor
Julian L Henley
Original Assignee
Biophoretic Therapeutic System
Julian L Henley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/153,640 external-priority patent/US6148231A/en
Priority claimed from US09/205,751 external-priority patent/US6385487B1/en
Application filed by Biophoretic Therapeutic System, Julian L Henley filed Critical Biophoretic Therapeutic System
Priority to JP2000569706A priority Critical patent/JP4297401B2/en
Priority to EP99924478A priority patent/EP1121059A4/en
Priority to CA002343893A priority patent/CA2343893C/en
Priority to AU40966/99A priority patent/AU763197B2/en
Publication of WO2000015120A1 publication Critical patent/WO2000015120A1/en
Publication of WO2000015120A8 publication Critical patent/WO2000015120A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

Non-reusable, medicament-dispensing applicator electrodes (10) adapted for use with an iontophoresis device or an ionosonic device for facilitating delivery of medication across the cutaneous membrane into adjacent underlying tissues, and blood vessels. The embodiments of the iontophoresis electrode include an open mesh (12) having cells (12a) in the medicament dispensing portions (11) of the electrode which retain a medicament in the form of liquid, gel or ointment. The cells are adapted to contain, to iontophoretically dispense, and deliver medicament. The medicament-dispensing electrodes (70) are composite or unitary in construction and may be useful in the treatment of acne, and also genital herpes simplex infection. The delivery electrode (71), when used in accordance with the medicated electrode, and method described herein, demonstrated ⊃90 % treatment efficacy in clinical trials for the treatment of genital herpes. The applicator electrode may also be used with an ionosonic handpiece (40).
PCT/US1999/011440 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes WO2000015120A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000569706A JP4297401B2 (en) 1998-09-15 1999-05-24 Drug delivery electrode by ion osmosis therapy
EP99924478A EP1121059A4 (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes
CA002343893A CA2343893C (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes
AU40966/99A AU763197B2 (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/153,640 US6148231A (en) 1998-09-15 1998-09-15 Iontophoretic drug delivery electrodes and method
US09/205,751 US6385487B1 (en) 1996-05-08 1998-12-04 Methods for electrokinetic delivery of medicaments
US09/153,640 1998-12-04
US09/205,751 1998-12-04

Publications (2)

Publication Number Publication Date
WO2000015120A1 WO2000015120A1 (en) 2000-03-23
WO2000015120A8 true WO2000015120A8 (en) 2001-10-04

Family

ID=26850728

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011440 WO2000015120A1 (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes

Country Status (5)

Country Link
EP (1) EP1121059A4 (en)
JP (1) JP4297401B2 (en)
AU (1) AU763197B2 (en)
CA (1) CA2343893C (en)
WO (1) WO2000015120A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US20040236269A1 (en) * 2002-09-25 2004-11-25 Marchitto Kevin S. Microsurgical tissue treatment system
CA2567688C (en) * 2004-05-28 2016-08-02 Jan De Geest Communication unit for a person's skin
AU2007295877B2 (en) 2006-09-15 2013-04-18 Cancure Limited Pro-oxidant anti-cancer compounds
WO2017106815A1 (en) * 2015-12-17 2017-06-22 Hg Medical Technologies Llc Electro kinetic transdermal and trans mucosal delivery accelerator device

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US279524A (en) * 1883-06-19 Thimble
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
US4838273A (en) * 1979-04-30 1989-06-13 Baxter International Inc. Medical electrode
US4856188A (en) * 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
US4765343A (en) * 1985-01-29 1988-08-23 Biosonics, Inc. Apparatus for transferring electrical energy to and from living tissue
JPH0647026B2 (en) * 1986-07-11 1994-06-22 美智士 谷 Electromagnetic therapy device
JPS63135179A (en) * 1986-11-26 1988-06-07 立花　俊郎 Subcataneous drug administration set
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
JP2788307B2 (en) * 1989-11-30 1998-08-20 住友ベークライト株式会社 Drug dosing device
US5318510A (en) * 1991-06-11 1994-06-07 Deknatel Technology Corporation, Inc. Collection device
US5589563A (en) 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
JPH0591693U (en) * 1992-05-22 1993-12-14 恒 福村 Electrotherapy equipment
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5458569A (en) * 1993-06-08 1995-10-17 Becton Dickinson And Company Wearable iontophoresis system
JP2818999B2 (en) * 1993-11-22 1998-10-30 ドラッグ デリバリー システムズ インコーポレイテッド Transdermal drug applicator
JPH07194711A (en) * 1993-12-28 1995-08-01 Tokyo Iken Kk Gloves for electric treating instrument
JPH09103496A (en) * 1995-10-12 1997-04-22 Etsuko Nozoe Iontophoresis device
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use

Also Published As

Publication number Publication date
CA2343893C (en) 2008-12-30
AU4096699A (en) 2000-04-03
JP4297401B2 (en) 2009-07-15
WO2000015120A1 (en) 2000-03-23
EP1121059A1 (en) 2001-08-08
EP1121059A4 (en) 2006-04-05
CA2343893A1 (en) 2000-03-23
AU763197B2 (en) 2003-07-17
JP2002524184A (en) 2002-08-06

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