WO2000015120A8 - Iontophoretic drug delivery electrodes - Google Patents

Iontophoretic drug delivery electrodes

Info

Publication number
WO2000015120A8
WO2000015120A8 PCT/US1999/011440 US9911440W WO2000015120A8 WO 2000015120 A8 WO2000015120 A8 WO 2000015120A8 US 9911440 W US9911440 W US 9911440W WO 2000015120 A8 WO2000015120 A8 WO 2000015120A8
Authority
WO
Grant status
Application
Patent type
Prior art keywords
electrode
medicament
dispensing
treatment
delivery
Prior art date
Application number
PCT/US1999/011440
Other languages
French (fr)
Other versions
WO2000015120A1 (en )
Inventor
Julian L Henley
Original Assignee
Biophoretic Therapeutic System
Julian L Henley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Abstract

Non-reusable, medicament-dispensing applicator electrodes (10) adapted for use with an iontophoresis device or an ionosonic device for facilitating delivery of medication across the cutaneous membrane into adjacent underlying tissues, and blood vessels. The embodiments of the iontophoresis electrode include an open mesh (12) having cells (12a) in the medicament dispensing portions (11) of the electrode which retain a medicament in the form of liquid, gel or ointment. The cells are adapted to contain, to iontophoretically dispense, and deliver medicament. The medicament-dispensing electrodes (70) are composite or unitary in construction and may be useful in the treatment of acne, and also genital herpes simplex infection. The delivery electrode (71), when used in accordance with the medicated electrode, and method described herein, demonstrated ⊃90 % treatment efficacy in clinical trials for the treatment of genital herpes. The applicator electrode may also be used with an ionosonic handpiece (40).
PCT/US1999/011440 1996-05-08 1999-05-24 Iontophoretic drug delivery electrodes WO2000015120A8 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US09/153,640 1998-09-15
US09153640 US6148231A (en) 1998-09-15 1998-09-15 Iontophoretic drug delivery electrodes and method
US09205751 US6385487B1 (en) 1996-05-08 1998-12-04 Methods for electrokinetic delivery of medicaments
US09/205,751 1998-12-04

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA 2343893 CA2343893C (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes
EP19990924478 EP1121059A4 (en) 1998-09-15 1999-05-24 Iontophoretic drug delivery electrodes
JP2000569706A JP4297401B2 (en) 1998-09-15 1999-05-24 Drug supply electrode by iontophoresis

Publications (2)

Publication Number Publication Date
WO2000015120A1 true WO2000015120A1 (en) 2000-03-23
WO2000015120A8 true true WO2000015120A8 (en) 2001-10-04

Family

ID=26850728

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011440 WO2000015120A8 (en) 1996-05-08 1999-05-24 Iontophoretic drug delivery electrodes

Country Status (4)

Country Link
EP (1) EP1121059A4 (en)
JP (1) JP4297401B2 (en)
CA (1) CA2343893C (en)
WO (1) WO2000015120A8 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US20040236269A1 (en) * 2002-09-25 2004-11-25 Marchitto Kevin S. Microsurgical tissue treatment system
CA2567688C (en) 2004-05-28 2016-08-02 Geest Jan De Communication unit for a person's skin
KR101482803B1 (en) 2006-09-15 2015-01-15 스티븐 존 랄프 Pro-oxidant anti-cancer compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US279524A (en) * 1883-06-19 Thimble
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
US4838273A (en) * 1979-04-30 1989-06-13 Baxter International Inc. Medical electrode
US4856188A (en) * 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
JPH0363913B2 (en) * 1986-11-26 1991-10-03 Toshiro Tachibana
US5589563A (en) 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5458569A (en) * 1993-06-08 1995-10-17 Becton Dickinson And Company Wearable iontophoresis system
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use

Also Published As

Publication number Publication date Type
JP2002524184A (en) 2002-08-06 application
WO2000015120A1 (en) 2000-03-23 application
CA2343893C (en) 2008-12-30 grant
EP1121059A1 (en) 2001-08-08 application
EP1121059A4 (en) 2006-04-05 application
CA2343893A1 (en) 2000-03-23 application
JP4297401B2 (en) 2009-07-15 grant

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