DE60036277D1 - Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen - Google Patents

Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen

Info

Publication number
DE60036277D1
DE60036277D1 DE60036277T DE60036277T DE60036277D1 DE 60036277 D1 DE60036277 D1 DE 60036277D1 DE 60036277 T DE60036277 T DE 60036277T DE 60036277 T DE60036277 T DE 60036277T DE 60036277 D1 DE60036277 D1 DE 60036277D1
Authority
DE
Germany
Prior art keywords
nucleic acid
acid amplification
test device
carrying
amplification reactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036277T
Other languages
English (en)
Other versions
DE60036277T2 (de
Inventor
Brian Kluttz
Lawrence Burg
Garry Tegeler
Louis Graziano
Christopher Cotter
Michel Guy
James Greer
Geoff A Mckinley
Luigi Catanzariti
Robert Glassford
James Clement Bishop
Bruno Colin
Cecile Paris
Thomas Wang
Michael Morin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux Inc
Original Assignee
Biomerieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Inc filed Critical Biomerieux Inc
Publication of DE60036277D1 publication Critical patent/DE60036277D1/de
Application granted granted Critical
Publication of DE60036277T2 publication Critical patent/DE60036277T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00366—Several different temperatures used

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
DE60036277T 1999-10-18 2000-09-29 Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen Expired - Lifetime DE60036277T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/420,139 US6410275B1 (en) 1997-05-02 1999-10-18 Disposable test devices for performing nucleic acid amplification reactions
US420139 1999-10-18
PCT/US2000/026736 WO2001028683A1 (en) 1999-10-18 2000-09-29 Disposable test devices for performing nucleic acid amplification reactions

Publications (2)

Publication Number Publication Date
DE60036277D1 true DE60036277D1 (de) 2007-10-18
DE60036277T2 DE60036277T2 (de) 2008-06-05

Family

ID=23665241

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60036277T Expired - Lifetime DE60036277T2 (de) 1999-10-18 2000-09-29 Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen

Country Status (13)

Country Link
US (1) US6410275B1 (de)
EP (1) EP1146961B1 (de)
JP (1) JP2003512032A (de)
KR (1) KR20010093850A (de)
AT (1) ATE372166T1 (de)
AU (1) AU753903B2 (de)
BR (1) BR0007223A (de)
CA (1) CA2348691A1 (de)
DE (1) DE60036277T2 (de)
ES (1) ES2292473T3 (de)
IL (1) IL141985A0 (de)
MX (1) MXPA01003181A (de)
WO (1) WO2001028683A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6429007B1 (en) * 1997-05-02 2002-08-06 BIOMéRIEUX, INC. Nucleic acid amplification reaction station for disposable test devices
DE10306018A1 (de) * 2003-02-13 2004-09-09 Siemens Ag Analyse- und Diagnostikinstrument
US7090803B1 (en) * 2003-10-28 2006-08-15 American Bio Medica Corporation Lateral flow immunoassay device
US7939030B2 (en) 2003-10-29 2011-05-10 Mec Dynamics Corp. Micro mechanical methods and systems for performing assays
WO2006123660A1 (ja) * 2005-05-17 2006-11-23 Wako Pure Chemical Industries, Ltd. 連結試薬容器
EP1963853B1 (de) * 2005-12-21 2016-03-09 Meso Scale Technologies, LLC Testmodule mit testreagenzien sowie verfahren zur herstellung und verwendung davon
MX338460B (es) 2005-12-21 2016-04-15 Meso Scale Technologies Llc Aparatos, metodos y reactivos de ensayo.
US20090098025A1 (en) * 2006-05-11 2009-04-16 Nobuhiro Hanafusa Reaction container kit
EP3450019A1 (de) * 2006-07-28 2019-03-06 Diagnostics for the Real World, Ltd Vorrichtung und system zur verarbeitung einer probe
JP4933301B2 (ja) * 2007-02-22 2012-05-16 キヤノン株式会社 検体処理装置
CA3135182C (en) 2007-04-04 2024-01-23 Ande Corporation Plastic microfluidic separation and detection platforms
EP2465609B1 (de) 2007-06-21 2016-12-28 Gen-Probe Incorporated Verfahren zum Mischen der Inhalte einer Nachweiskammer
GB2456079B (en) 2007-08-17 2010-07-14 Diagnostics For The Real World Device, system and method for processing a sample
DE102008007352B4 (de) * 2008-01-28 2010-04-22 Prionics Ag Vorrichtung zur Gewinnung, Konservierung und Lagerung von Probenmaterial mit einem Probenbehälter
JP2012529908A (ja) 2009-06-15 2012-11-29 ネットバイオ・インコーポレーテッド 法医学的ｄｎａの定量化のための改善された方法
WO2014087149A2 (en) * 2012-12-03 2014-06-12 The Secretary Of State For Environment, Food And Rural Affairs Device and apparatus
KR101955330B1 (ko) * 2012-12-21 2019-03-07 삼성전자주식회사 핵산 분석용 반응 시약 공급 장치
US9481903B2 (en) 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
US10393738B2 (en) 2013-11-12 2019-08-27 Boditech Med Inc. Multi-well cuvette provided with integrated reaction and detection means
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
JP6858540B2 (ja) 2016-12-08 2021-04-14 株式会社ミズホメディー 核酸増幅反応用デバイス
US11077444B2 (en) * 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
JP2020529427A (ja) 2017-08-04 2020-10-08 バイスクルテクス・リミテッド Ｃｄ１３７に対して特異的な二環式ペプチドリガンド
CN107523487B (zh) * 2017-09-18 2024-03-19 星源智（珠海）生物科技有限公司 一种集成化管状反应装置
US10935149B2 (en) 2018-03-15 2021-03-02 University Of Washington Temperature-actuated valve, fluidic device, and related methods of use
AU2021297973A1 (en) * 2020-06-24 2023-01-19 President And Fellows Of Harvard College Automatic multi-step reaction device

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579303A (en) 1968-03-06 1971-05-18 Donald E Pickering System for handling specimens and other substances in medicine and physical sciences
US3833406A (en) 1972-08-07 1974-09-03 Owens Illinois Inc Closed container with desiccant coating on inside surface thereof
US3994594A (en) 1975-08-27 1976-11-30 Technicon Instruments Corporation Cuvette and method of use
US4207394A (en) 1976-01-28 1980-06-10 Mcdonnell Douglas Corporation Process and apparatus for analyzing specimens for the presence of microorganisms therein
US4043678A (en) 1976-03-01 1977-08-23 Technicon Instruments Corporation Cuvette
US4119407A (en) 1976-03-08 1978-10-10 Bio-Dynamics, Inc. Cuvette with reagent release means
US4116775A (en) 1976-05-03 1978-09-26 Mcdonnell Douglas Corporation Machine and process for reading cards containing medical specimens
US4038151A (en) 1976-07-29 1977-07-26 Mcdonnell Douglas Corporation Card for use in an automated microbial detection system
US4106675A (en) 1976-12-22 1978-08-15 The Kendall Company Liquid sampling device
US4195060A (en) 1978-02-08 1980-03-25 Abbott Laboratories Liquid reagent cartridge cuvette
US4330627A (en) 1979-02-09 1982-05-18 Ryder International Corporation Testing tray
US4267833A (en) 1979-04-24 1981-05-19 American Hospital Supply Corporation Method of flushing a medical fluid
US4332769A (en) 1980-09-10 1982-06-01 Chemetrics, Inc. Disposable titration device
US4605536A (en) 1984-05-29 1986-08-12 Veb Metaplast Quedlinburg Cuvette for projection display of chemical experiments
FR2612297B1 (fr) 1987-03-10 1990-10-05 Pasteur Diagnostics Dispositif de laboratoire pour analyse necessitant la mise en contact transitoire d'une phase solide et d'une phase liquide
US4956148A (en) 1987-04-22 1990-09-11 Abbott Laboratories Locking rack and disposable sample cartridge
US4943522A (en) 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
CA1340843C (en) 1987-07-31 1999-12-07 J. Lawrence Burg Selective amplification of target polynucleotide sequences
IL88073A0 (en) 1987-12-17 1989-06-30 Miles Inc Analytical reagent mixing apparatus and method for performing sequential analytical reactions
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
DE4021628A1 (de) 1990-07-06 1992-01-16 Kiha Textilien Gmbh Faserstruktur und daraus erhaltenes formteil sowie verfahren zu dessen herstellung
US5270183A (en) 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US5324481A (en) 1991-06-03 1994-06-28 Abbott Laboratories Carousel for assay specimen carrier
FR2679255B1 (fr) 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
US5605665A (en) 1992-03-27 1997-02-25 Abbott Laboratories Reaction vessel
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
WO1993022461A1 (en) 1992-05-06 1993-11-11 Gen-Probe Incorporated Nucleic acid sequence amplification method, composition and kit
US5364591A (en) 1992-06-01 1994-11-15 Eastman Kodak Company Device for moving a target-bearing solid through a liquid for detection while being contained
EP0636413B1 (de) 1993-07-28 2001-11-14 PE Corporation (NY) Vorrichtung und Verfahren zur Nukleinsäurevervielfältigung
US5645801A (en) 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
EP1245286B1 (de) 1993-10-22 2009-11-25 Abbott Laboratories Teströrchen und Verfahren zur Minimisierung der Kontamination
EP0662345B1 (de) 1994-01-06 2000-05-31 Johnson & Johnson Clinical Diagnostics, Inc. Vorrichtung zum Erwärmen einer Flüssigkeitsführenden Kammer von einer Reaktionscuvette
CA2143365A1 (en) 1994-03-14 1995-09-15 Hugh V. Cottingham Nucleic acid amplification method and apparatus
US5725831A (en) 1994-03-14 1998-03-10 Becton Dickinson And Company Nucleic acid amplification apparatus
CA2192324C (en) 1994-06-10 2006-10-10 Venkatachala Natarajan Recombinant virus and related method of quantitating same
US5888826A (en) 1994-06-30 1999-03-30 Dade Behring Inc. Combination reagent holding and test device
US5602037A (en) 1994-06-30 1997-02-11 Dade International, Inc. Combination reagent holding and test device
US5639428A (en) * 1994-07-19 1997-06-17 Becton Dickinson And Company Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
WO1997003348A1 (en) 1995-07-13 1997-01-30 Immunological Associates Of Denver Self-contained device integrating nucleic acid extraction, amplification and detection
JPH09262084A (ja) 1996-03-27 1997-10-07 Technol Res Assoc Of Medical & Welfare Apparatus Ｄｎａ増幅装置
US5989499A (en) * 1997-05-02 1999-11-23 Biomerieux, Inc. Dual chamber disposable reaction vessel for amplification reactions
US5786182A (en) 1997-05-02 1998-07-28 Biomerieux Vitek, Inc. Dual chamber disposable reaction vessel for amplification reactions, reaction processing station therefor, and methods of use
AU772769B2 (en) 1998-08-10 2004-05-06 Digilab, Inc. A thermal/fluidic cycling device for the purpose of nucleic acid hybridization

Also Published As

Publication number Publication date
IL141985A0 (en) 2002-03-10
ATE372166T1 (de) 2007-09-15
ES2292473T3 (es) 2008-03-16
KR20010093850A (ko) 2001-10-29
BR0007223A (pt) 2001-12-04
AU753903B2 (en) 2002-10-31
JP2003512032A (ja) 2003-04-02
DE60036277T2 (de) 2008-06-05
EP1146961A1 (de) 2001-10-24
WO2001028683A1 (en) 2001-04-26
US6410275B1 (en) 2002-06-25
AU7731200A (en) 2001-04-30
WO2001028683A8 (en) 2001-09-07
CA2348691A1 (en) 2001-04-26
MXPA01003181A (es) 2003-05-15
EP1146961B1 (de) 2007-09-05

Similar Documents

Publication Publication Date Title
DE60036277D1 (de) Testgerät zur durchführung von nukleinsäure-amplifikationsreaktionen
ATE454625T1 (de) System zum erkennen von substanzen
ATE260988T1 (de) Vorrichtung und verfahren zur durchführung und überwachung von polymerase kettenreaktionen
DE60212614D1 (de) Vorrichtung zur dosierung von reagenzien
DE69033796D1 (de) Verfahren und gerät zum nachweis und zur quantifizierung von glukose in körperflüssigkeiten
DE68913962D1 (de) Bioreaktor und vorrichtung zur kultivierung von tierischen zellen.
ATE430621T1 (de) Biologische vorrichtung
ATE412049T1 (de) Multiarraysystem zur integration von bioarrays
ATE346156T1 (de) Umkehrtransfektionsverfahren
DE50312579D1 (de) Vorrichtung zur Detektion von Targetmolekülen
ATE84616T1 (de) Vorrichtung fuer biologische analysen mittels einer chemischen serum-reaktion.
EP2107482A3 (de) Verfahren und System zur Analyse von Reaktionen mittels eines Informationssystems
DE60035719D1 (de) Vorrichtung zur ermittlung von herzrate und anormaler beatmung
MXPA02007101A (es) Suministro de muestra auxiliar para un analizador clinico.
DE58900416D1 (de) Vorrichtung zur durchfuehrung chemischer reaktionsfolgen.
IS7640A (is) Samsömun á fákirnum til hremmingar, greiningar ogmagngreiningar á lifrarbólgu A veirukjarnsýru
DE60027045D1 (de) Oligonukleotide und diese enthaltende komplexe zur detektion der anwesenheit oder abwesenheit einer zielnukleinsäure in einer probe
ATE393913T1 (de) Biochip zur archivierung und labormedizinischen analyse von biologischem probenmaterial
ES8801731A1 (es) Un aparato para realizar un analisis
DE59203610D1 (de) Reaktor zur Durchführung biologischer Reaktionen mittels Biokatalysatoren.
DE69800720D1 (de) Reagenz zur Färbung von Blutzellen
NO870794D0 (no) Fremgangsmaate til kvantitativ bestemmelse av nukleinsyremolekyler og reagenspakke til bruk ved utfoerelse av fremgangsmaaten.
DE68909997D1 (de) Vorrichtung zur Kultur von tierischen Zellen, Kulturmethode und Mittel zum Nachweis der Kultur.
DE59806570D1 (de) Vorrichtung zur Dosierung von medizinischen Flüssigkeiten
DE59906395D1 (de) Vorrichtung zur durchführung von chemischen reaktionen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition