DE60034672D1 - Reporterverbindungen und verfahren zur bestimmung des lipidisierungsstatus einer zelle - Google Patents

Reporterverbindungen und verfahren zur bestimmung des lipidisierungsstatus einer zelle

Info

Publication number
DE60034672D1
DE60034672D1 DE60034672T DE60034672T DE60034672D1 DE 60034672 D1 DE60034672 D1 DE 60034672D1 DE 60034672 T DE60034672 T DE 60034672T DE 60034672 T DE60034672 T DE 60034672T DE 60034672 D1 DE60034672 D1 DE 60034672D1
Authority
DE
Germany
Prior art keywords
cell
determining
lipidization
status
entity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60034672T
Other languages
English (en)
Inventor
Acker Koenraad Lodewijk Van
Inge Dierinck
Rudi Wilfried Pauwels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Infectious Diseases Diagnostics BVBA
Original Assignee
Tibotec BVBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec BVBA filed Critical Tibotec BVBA
Application granted granted Critical
Publication of DE60034672D1 publication Critical patent/DE60034672D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes
DE60034672T 1999-05-26 2000-05-26 Reporterverbindungen und verfahren zur bestimmung des lipidisierungsstatus einer zelle Expired - Lifetime DE60034672D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99201659A EP1055929A1 (de) 1999-05-26 1999-05-26 Mittel und Verfahren für Medizinentdeckung und phenotypische Charakterisierung von Zellen
PCT/EP2000/004919 WO2000073497A1 (en) 1999-05-26 2000-05-26 Reporter molecules and methods for assaying the lipidation status of a cell

Publications (1)

Publication Number Publication Date
DE60034672D1 true DE60034672D1 (de) 2007-06-14

Family

ID=8240238

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60022879T Expired - Fee Related DE60022879T2 (de) 1999-05-26 2000-05-26 Reporterverbindungen und verfahren zur auffindung von hochspezifische proteaseaktivität
DE60034672T Expired - Lifetime DE60034672D1 (de) 1999-05-26 2000-05-26 Reporterverbindungen und verfahren zur bestimmung des lipidisierungsstatus einer zelle

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60022879T Expired - Fee Related DE60022879T2 (de) 1999-05-26 2000-05-26 Reporterverbindungen und verfahren zur auffindung von hochspezifische proteaseaktivität

Country Status (9)

Country Link
US (1) US7129036B1 (de)
EP (3) EP1055929A1 (de)
AT (2) ATE361374T1 (de)
AU (2) AU778272B2 (de)
CA (2) CA2374038A1 (de)
DE (2) DE60022879T2 (de)
DK (1) DK1185873T3 (de)
ES (1) ES2249273T3 (de)
WO (2) WO2000073802A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756207B1 (en) 1997-02-27 2004-06-29 Cellomics, Inc. System for cell-based screening
EP2135943A1 (de) * 2001-07-30 2009-12-23 Meso Scale Technologies, LLC. Prüfelektrode mit festen Lipid- bzw. Proteinschichten, Herstellungsverfahren dafür und Verfahren zu deren Verwendung bei Lumineszenzprüfmessungen
CN101684161A (zh) 2001-08-10 2010-03-31 阿赫姆生物系统公司 蛋白酶检测系统
WO2009015071A1 (en) * 2007-07-23 2009-01-29 Dharmacon, Inc. Screening of micro-rna cluster inhibitor pools
WO2009100760A1 (en) * 2008-02-13 2009-08-20 Novartis Ag Cellular screening assay for modulators of mevalonate pathway
US20150026834A1 (en) 2012-03-07 2015-01-22 The Johns Kopkins University Anastasis biosensor
EP3542162B1 (de) * 2016-11-16 2021-09-01 The Johns Hopkins University Anastasebiosensor
WO2019099769A1 (en) 2017-11-16 2019-05-23 The Johns Hopkins University Anastasis biosensor caspase tracker

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226065D0 (en) * 1992-12-14 1993-02-10 Ici Plc Peptides
DK0815257T3 (da) * 1995-01-31 2002-04-22 Bioimage As Fremgangsmåde til karakterisering af biologisk aktive stoffer
JP2000504220A (ja) 1996-01-23 2000-04-11 ライガル ファーマシューティカルズ インコーポレイテッド トランス支配性細胞内作用因子ペプチドおよびｒｎａ分子のスクリーニング方法
DK0986753T4 (da) * 1997-04-07 2005-12-19 Bioimage As Fremgangsmåde til uddragning af kvantitativ information, hvad angår en påvirkning af et cellulært respons
CN1281346A (zh) * 1997-10-10 2001-01-24 西托维亚公司 新型荧光报道分子及其应用,包括对胱天肽酶的测定

Also Published As

Publication number Publication date
ES2249273T3 (es) 2006-04-01
EP1185689B1 (de) 2007-05-02
DK1185873T3 (da) 2006-01-30
AU5217700A (en) 2000-12-18
DE60022879T2 (de) 2006-07-20
WO2000073497A1 (en) 2000-12-07
EP1185873A1 (de) 2002-03-13
ATE305612T1 (de) 2005-10-15
ATE361374T1 (de) 2007-05-15
EP1055929A1 (de) 2000-11-29
AU777118B2 (en) 2004-09-30
EP1185689A1 (de) 2002-03-13
EP1185873B8 (de) 2005-11-23
CA2374038A1 (en) 2000-12-07
DE60022879D1 (de) 2006-02-09
US7129036B1 (en) 2006-10-31
AU5676700A (en) 2000-12-18
AU778272B2 (en) 2004-11-25
EP1185873B1 (de) 2005-09-28
CA2374047A1 (en) 2000-12-07
WO2000073802A1 (en) 2000-12-07

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Legal Events

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8332 No legal effect for de