DE60029961D1 - Verankerte strangverdrängungsverstärkung auf einem elektronisch adressierbaren microchip - Google Patents
Verankerte strangverdrängungsverstärkung auf einem elektronisch adressierbaren microchipInfo
- Publication number
- DE60029961D1 DE60029961D1 DE60029961T DE60029961T DE60029961D1 DE 60029961 D1 DE60029961 D1 DE 60029961D1 DE 60029961 T DE60029961 T DE 60029961T DE 60029961 T DE60029961 T DE 60029961T DE 60029961 D1 DE60029961 D1 DE 60029961D1
- Authority
- DE
- Germany
- Prior art keywords
- electronically addressable
- anchored
- primer pair
- strand extension
- extension reinforcement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Graft Or Block Polymers (AREA)
- Reinforcement Elements For Buildings (AREA)
- Pinball Game Machines (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/290,000 US6531302B1 (en) | 1999-04-12 | 1999-04-12 | Anchored strand displacement amplification on an electronically addressable microchip |
US290000 | 1999-04-12 | ||
PCT/US2000/009838 WO2000060919A2 (en) | 1999-04-12 | 2000-04-11 | Anchored strand displacement amplification on an electronically addressable microchip |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60029961D1 true DE60029961D1 (de) | 2006-09-21 |
DE60029961T2 DE60029961T2 (de) | 2007-03-01 |
Family
ID=23114102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60029961T Expired - Fee Related DE60029961T2 (de) | 1999-04-12 | 2000-04-11 | Verankerte strangverdrängungs-amplifizierung auf einem elektronisch adressierbaren mikrochip |
Country Status (7)
Country | Link |
---|---|
US (2) | US6531302B1 (de) |
EP (1) | EP1192720B1 (de) |
JP (1) | JP2003510012A (de) |
AT (1) | ATE335848T1 (de) |
CA (1) | CA2369148A1 (de) |
DE (1) | DE60029961T2 (de) |
WO (1) | WO2000060919A2 (de) |
Families Citing this family (31)
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US6379897B1 (en) | 2000-11-09 | 2002-04-30 | Nanogen, Inc. | Methods for gene expression monitoring on electronic microarrays |
US6238868B1 (en) * | 1999-04-12 | 2001-05-29 | Nanogen/Becton Dickinson Partnership | Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology |
JP2002541475A (ja) * | 1999-04-12 | 2002-12-03 | ナノゲン/ベクトン・ディッキンソン・パートナーシップ | 鎖置換増幅およびバイオエレクトロニック・マイクロチップ技術を用いる核酸配列の増幅および分離 |
US6531302B1 (en) * | 1999-04-12 | 2003-03-11 | Nanogen/Becton Dickinson Partnership | Anchored strand displacement amplification on an electronically addressable microchip |
AU2002241168B2 (en) | 2001-04-02 | 2007-10-25 | Point-2-Point Genomics Ltd. | Polynucleotide analysis using combinatorial PCR |
DE60226856D1 (de) | 2001-04-20 | 2008-07-10 | Penn State Res Found | Verfahren zur manipulation von nukleinsäuren |
US6884586B2 (en) | 2001-07-15 | 2005-04-26 | Keck Graduate Institute | Methylation analysis using nicking agents |
WO2003008624A2 (en) | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
US20030175709A1 (en) * | 2001-12-20 | 2003-09-18 | Murphy George L. | Method and system for depleting rRNA populations |
DE10201138B4 (de) * | 2002-01-08 | 2005-03-10 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern durch exponentielle Ligation hybridisierter Sondenoligonukleotide (MLA) |
US7005265B1 (en) * | 2002-06-20 | 2006-02-28 | Wenhong Fan | Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays |
JP2004097173A (ja) * | 2002-07-17 | 2004-04-02 | Toyo Kohan Co Ltd | 静電層を有する固体支持体及びその用途 |
DE10253966B4 (de) * | 2002-11-19 | 2005-03-24 | Clondiag Chip Technologies Gmbh | Microarray-basiertes Verfahren zur Amplifikation und Detektion von Nukleinsäuren in einem kontinuierlichen Prozess |
DE10259819B4 (de) | 2002-12-19 | 2006-07-13 | Siemens Ag | Verfahren zur PCR-Amplifikation und Detektion von Nucleotidsequenzen |
DE602004026077D1 (de) * | 2003-09-10 | 2010-04-29 | Althea Technologies Inc | Erstellung von expressionsprofilen unter verwendung von mikroarrays |
DE10353419B3 (de) * | 2003-11-09 | 2005-06-30 | Epigenomics Ag | Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA-Sequenzen mittels hemimethylierungssensitiver Restriktionsenzyme |
US7314714B2 (en) * | 2003-12-19 | 2008-01-01 | Affymetrix, Inc. | Method of oligonucleotide synthesis |
WO2010096202A2 (en) | 2009-02-23 | 2010-08-26 | Georgetown University | Sequence-specific detection of nucleotide sequences |
JP2009500020A (ja) * | 2005-07-01 | 2009-01-08 | バイオヴェリス コーポレイション | 核酸を検出、増幅および/また単離するための組成物および方法 |
US20090137415A1 (en) * | 2005-08-05 | 2009-05-28 | Euclid Diagnostics Llc | SUBTRACTIVE SEPARATION AND AMPLIFICATION OF NON-RIBOSOMAL TRANSCRIBED RNA (nrRNA) |
TWI313122B (en) * | 2006-09-14 | 2009-08-01 | Transmission parameter recognition apparatus and method thereof | |
US20090215050A1 (en) | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
US9309566B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid amplification |
US9309557B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
FR2949120A1 (fr) * | 2009-08-13 | 2011-02-18 | Centre Nat Rech Scient | Procede de detection d'un adn circularise et utilisation de ce procede pour la detection de mutations |
EP3564392B1 (de) * | 2010-12-17 | 2021-11-24 | Life Technologies Corporation | Verfahren für nukleinsäureamplifikation |
CN116622812A (zh) | 2013-03-14 | 2023-08-22 | 生命技术公司 | 基质阵列和其制备方法 |
WO2016065182A1 (en) * | 2014-10-22 | 2016-04-28 | Ibis Biosciences, Inc. | Systems and methods for nucleic acid capture |
CA2980624C (en) * | 2015-03-25 | 2023-08-29 | Axela Inc. | Solid phase nucleic acid target capture and replication using strand displacing polymerases |
GB201812149D0 (en) * | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
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EP0168530B1 (de) * | 1984-07-05 | 1990-04-04 | Docdata N.V. | Verfahren und Vorrichtung zum Reproduzieren von Reliefstrukturen auf einem Substrat |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
US4787963A (en) * | 1987-05-04 | 1988-11-29 | Syntro Corporation | Method and means for annealing complementary nucleic acid molecules at an accelerated rate |
CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
US6054270A (en) * | 1988-05-03 | 2000-04-25 | Oxford Gene Technology Limited | Analying polynucleotide sequences |
US5130238A (en) * | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
US5171392A (en) * | 1988-11-08 | 1992-12-15 | Pioneer Electronic Corporation | Method of producing an optical information record carrier |
US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
EP0478630B1 (de) * | 1989-06-12 | 1993-09-01 | Cis Bio International | Verfahren zum nachweis von spezifischen sequenzen von nukleinsäuren und ihre verwendungen |
US5573907A (en) | 1990-01-26 | 1996-11-12 | Abbott Laboratories | Detecting and amplifying target nucleic acids using exonucleolytic activity |
US5516663A (en) | 1990-01-26 | 1996-05-14 | Abbott Laboratories | Ligase chain reaction with endonuclease IV correction and contamination control |
US5494810A (en) * | 1990-05-03 | 1996-02-27 | Cornell Research Foundation, Inc. | Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease |
US5527670A (en) * | 1990-09-12 | 1996-06-18 | Scientific Generics Limited | Electrochemical denaturation of double-stranded nucleic acid |
WO1992008808A1 (en) | 1990-11-14 | 1992-05-29 | Siska Diagnostics, Inc. | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
US5380489A (en) | 1992-02-18 | 1995-01-10 | Eastman Kodak Company | Element and method for nucleic acid amplification and detection using adhered probes |
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JPH0580530A (ja) * | 1991-09-24 | 1993-04-02 | Hitachi Ltd | 薄膜パターン製造方法 |
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US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
DE69405451T2 (de) * | 1993-03-16 | 1998-03-12 | Koninkl Philips Electronics Nv | Verfahren und Vorrichtung zur Herstellung eines strukturierten Reliefbildes aus vernetztem Photoresist auf einer flachen Substratoberfläche |
US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
US5470723A (en) * | 1993-05-05 | 1995-11-28 | Becton, Dickinson And Company | Detection of mycobacteria by multiplex nucleic acid amplification |
US5840485A (en) * | 1993-05-27 | 1998-11-24 | Selectide Corporation | Topologically segregated, encoded solid phase libraries |
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US6531302B1 (en) * | 1999-04-12 | 2003-03-11 | Nanogen/Becton Dickinson Partnership | Anchored strand displacement amplification on an electronically addressable microchip |
US6238868B1 (en) * | 1999-04-12 | 2001-05-29 | Nanogen/Becton Dickinson Partnership | Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology |
US6309833B1 (en) * | 1999-04-12 | 2001-10-30 | Nanogen/Becton Dickinson Partnership | Multiplex amplification and separation of nucleic acid sequences on a bioelectronic microchip using asymmetric structures |
US6066461A (en) * | 1999-04-12 | 2000-05-23 | Becton Dickinson And Company | Amplification and detection of Campylobacter jejuni and Campylobacter coli |
US6274320B1 (en) * | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
-
1999
- 1999-04-12 US US09/290,000 patent/US6531302B1/en not_active Expired - Lifetime
-
2000
- 2000-04-11 DE DE60029961T patent/DE60029961T2/de not_active Expired - Fee Related
- 2000-04-11 AT AT00923282T patent/ATE335848T1/de not_active IP Right Cessation
- 2000-04-11 JP JP2000610270A patent/JP2003510012A/ja active Pending
- 2000-04-11 EP EP00923282A patent/EP1192720B1/de not_active Expired - Lifetime
- 2000-04-11 WO PCT/US2000/009838 patent/WO2000060919A2/en active Search and Examination
- 2000-04-11 CA CA002369148A patent/CA2369148A1/en not_active Abandoned
-
2003
- 2003-03-11 US US10/387,304 patent/US20030219804A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2369148A1 (en) | 2000-10-19 |
ATE335848T1 (de) | 2006-09-15 |
US20030219804A1 (en) | 2003-11-27 |
EP1192720A4 (de) | 2004-12-22 |
WO2000060919A2 (en) | 2000-10-19 |
EP1192720A2 (de) | 2002-04-03 |
US6531302B1 (en) | 2003-03-11 |
JP2003510012A (ja) | 2003-03-18 |
WO2000060919A3 (en) | 2002-01-03 |
DE60029961T2 (de) | 2007-03-01 |
WO2000060919B1 (en) | 2002-01-31 |
EP1192720B1 (de) | 2006-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |