DE60029129T2 - Schnelle gewebeaufbereitungsvorrichtung - Google Patents
Schnelle gewebeaufbereitungsvorrichtung Download PDFInfo
- Publication number
- DE60029129T2 DE60029129T2 DE60029129T DE60029129T DE60029129T2 DE 60029129 T2 DE60029129 T2 DE 60029129T2 DE 60029129 T DE60029129 T DE 60029129T DE 60029129 T DE60029129 T DE 60029129T DE 60029129 T2 DE60029129 T2 DE 60029129T2
- Authority
- DE
- Germany
- Prior art keywords
- reaction chamber
- use according
- tissue sample
- microwave
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000006243 chemical reaction Methods 0.000 claims abstract description 139
- 238000012545 processing Methods 0.000 claims abstract description 57
- 239000000126 substance Substances 0.000 claims abstract description 53
- 239000000203 mixture Substances 0.000 claims description 42
- 239000000243 solution Substances 0.000 claims description 33
- 230000005855 radiation Effects 0.000 claims description 27
- 238000005470 impregnation Methods 0.000 claims description 18
- 238000012546 transfer Methods 0.000 claims description 13
- 239000012530 fluid Substances 0.000 claims description 10
- 238000003860 storage Methods 0.000 claims description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 238000004891 communication Methods 0.000 claims description 8
- 238000009826 distribution Methods 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 238000009413 insulation Methods 0.000 claims description 5
- 239000012024 dehydrating agents Substances 0.000 claims description 3
- 239000002480 mineral oil Substances 0.000 claims description 2
- 235000010446 mineral oil Nutrition 0.000 claims description 2
- 150000002576 ketones Chemical class 0.000 claims 5
- 239000012457 nonaqueous media Substances 0.000 claims 2
- 239000000834 fixative Substances 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 abstract description 19
- 230000008901 benefit Effects 0.000 abstract description 4
- 239000000523 sample Substances 0.000 description 46
- 238000000034 method Methods 0.000 description 41
- 230000008569 process Effects 0.000 description 27
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 12
- 239000007788 liquid Substances 0.000 description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 8
- 239000000463 material Substances 0.000 description 7
- 230000008859 change Effects 0.000 description 6
- 230000018044 dehydration Effects 0.000 description 6
- 238000006297 dehydration reaction Methods 0.000 description 6
- 238000003745 diagnosis Methods 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 238000007796 conventional method Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000004744 fabric Substances 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 239000012188 paraffin wax Substances 0.000 description 5
- 230000001575 pathological effect Effects 0.000 description 4
- 230000007170 pathology Effects 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 238000010411 cooking Methods 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000011049 filling Methods 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
- 238000003754 machining Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000010186 staining Methods 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 238000005238 degreasing Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000012252 genetic analysis Methods 0.000 description 2
- 238000012735 histological processing Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 230000004043 responsiveness Effects 0.000 description 2
- 238000007363 ring formation reaction Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 238000003777 tissue processing method Methods 0.000 description 2
- 239000008096 xylene Substances 0.000 description 2
- 230000009946 DNA mutation Effects 0.000 description 1
- 229920004943 Delrin® Polymers 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000004939 coking Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 230000006240 deamidation Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000001744 histochemical effect Effects 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000003778 tissue fixation method Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000010618 wire wrap Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/64—Heating using microwaves
- H05B6/80—Apparatus for specific applications
- H05B6/806—Apparatus for specific applications for laboratory use
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B6/00—Heating by electric, magnetic or electromagnetic fields
- H05B6/64—Heating using microwaves
- H05B6/70—Feed lines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00524—Mixing by agitating sample carrier
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Constitution Of High-Frequency Heating (AREA)
- Surgical Instruments (AREA)
- Processing Of Meat And Fish (AREA)
- Disintegrating Or Milling (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Electrotherapy Devices (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17054599P | 1999-12-14 | 1999-12-14 | |
| US170545P | 1999-12-14 | ||
| PCT/US2000/033760 WO2001044783A1 (en) | 1999-12-14 | 2000-12-14 | Rapid tissue processor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60029129D1 DE60029129D1 (de) | 2006-08-10 |
| DE60029129T2 true DE60029129T2 (de) | 2006-11-09 |
Family
ID=22620292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60029129T Expired - Lifetime DE60029129T2 (de) | 1999-12-14 | 2000-12-14 | Schnelle gewebeaufbereitungsvorrichtung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20010043884A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1238256B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2003517601A (cg-RX-API-DMAC7.html) |
| KR (1) | KR100743727B1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE331946T1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2094001A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2394194C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60029129T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1238256T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2263509T3 (cg-RX-API-DMAC7.html) |
| WO (2) | WO2001044783A1 (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011055120A1 (de) * | 2011-04-20 | 2012-10-25 | Leica Biosystems Nussloch Gmbh | Verfahren zur Ausführung bei der Verarbeitung zumindest einer histologischen Probe |
| DE102021105932A1 (de) | 2021-03-11 | 2022-09-15 | Leica Biosystems Nussloch Gmbh | Verfahren zur Gewebeprozessierung und Gewebeprozessor |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1292818B1 (en) | 2000-06-09 | 2016-01-13 | The University Of Miami | Pathology grossing board |
| US7297311B2 (en) * | 2001-06-29 | 2007-11-20 | Sysmex Corporation | Automatic smear preparing apparatus and automatic sample analysis system having the same |
| GB0117919D0 (en) * | 2001-07-23 | 2001-09-12 | Thermo Shandon Ltd | Processor device with fume extraction |
| CN100473990C (zh) | 2001-10-01 | 2009-04-01 | 徠卡生物体系墨尔本控股有限公司 | 组织处理器 |
| DE10149345B4 (de) | 2001-10-06 | 2007-11-15 | Leica Mikrosysteme Gmbh | Vorrichtung zur schnellen Gewebepräparation für histologische Untersuchungen |
| US7468161B2 (en) * | 2002-04-15 | 2008-12-23 | Ventana Medical Systems, Inc. | Automated high volume slide processing system |
| US7138226B2 (en) | 2002-05-10 | 2006-11-21 | The University Of Miami | Preservation of RNA and morphology in cells and tissues |
| AU2003900924A0 (en) * | 2003-02-28 | 2003-03-13 | Medsaic Pty Ltd | Imaging device |
| EP1644715B1 (en) * | 2003-06-30 | 2007-01-03 | Academisch Ziekenhuis Groningen | Method for histoprocessing |
| US8554372B2 (en) | 2003-09-29 | 2013-10-08 | Leica Biosystems Melbourne Pty Ltd | System and method for histological tissue specimen processing |
| DE602004023104D1 (de) * | 2003-10-24 | 2009-10-22 | Univ Miami | Vereinfachte gewebeverarbeitung |
| US8236255B2 (en) | 2004-12-02 | 2012-08-07 | Lab Vision Corporation | Slide treatment apparatus and methods for use |
| JP4559889B2 (ja) * | 2005-03-24 | 2010-10-13 | 株式会社常光 | 脱灰・脱脂用容器蓋 |
| JP4549912B2 (ja) * | 2005-03-28 | 2010-09-22 | 株式会社常光 | 生体組織処理装置 |
| WO2007016935A1 (en) * | 2005-07-29 | 2007-02-15 | Histogenex Nv | Methods, reagents and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies |
| EP1929270B1 (en) | 2005-09-06 | 2021-03-03 | Leica Biosystems Melbourne Pty Ltd | Method and apparatus for handling tissue samples |
| JP2007093255A (ja) * | 2005-09-27 | 2007-04-12 | Jokoh Co Ltd | 脱灰・脱脂用容器蓋 |
| JP2007093254A (ja) * | 2005-09-27 | 2007-04-12 | Jokoh Co Ltd | 迅速脱灰・脱脂・固定装置 |
| US20070202607A1 (en) * | 2006-02-24 | 2007-08-30 | Revesz Robert N | Filtration apparatus and associated method for microwave-assisted chemistry |
| WO2007141888A1 (ja) * | 2006-06-05 | 2007-12-13 | Jokoh Co., Ltd | 生物組織固定装置 |
| US20080026366A1 (en) * | 2006-06-07 | 2008-01-31 | Newcomer Supply, Inc. | Biological fixative and method of using the biological fixative |
| AT504371B8 (de) | 2006-10-03 | 2008-09-15 | Leica Mikrosysteme Gmbh | Vorrichtung zur mikrowellen-gestützten präparation von proben |
| US9733166B2 (en) | 2006-12-18 | 2017-08-15 | Leica Biosystems Melbourne Pty Ltd | Device and method for tissue handling and embedding |
| EP2278295A1 (en) * | 2009-07-24 | 2011-01-26 | Milestone S.r.l. | Single cavity tissue histology tissue-processor |
| US20110045565A1 (en) * | 2009-08-18 | 2011-02-24 | Leica Biosystems Nussloch Gmbh | Apparatus and method for accelerated tissue infiltration by means of microwave excitation |
| US8067241B2 (en) | 2009-08-26 | 2011-11-29 | General Electric Company | Method and apparatus for antigen retrieval process |
| JP5858435B2 (ja) * | 2010-03-12 | 2016-02-10 | 国立研究開発法人理化学研究所 | 生物材料用透明化試薬、及びその利用 |
| EP2518468B1 (en) * | 2011-04-26 | 2019-07-24 | Milestone S.r.l. | Method, processor and carrier for processing frozen slices of tissue of biospecimens |
| EP2711682B1 (en) | 2011-05-20 | 2019-07-10 | Riken | Clarifying reagent for biological materials and use thereof |
| CN103975229B (zh) * | 2011-09-29 | 2017-09-22 | 迈阿密大学 | 作为冰冻切片的替代物的超快诊断组织制剂 |
| JP2014209090A (ja) * | 2013-03-29 | 2014-11-06 | シスメックス株式会社 | 細胞分析方法及び装置 |
| EP3035026A4 (en) | 2013-08-14 | 2017-04-26 | Riken | Composition for preparing biomaterial with excellent light-transmitting property, and use thereof |
| CN106644652B (zh) * | 2017-01-23 | 2020-01-03 | 山东省农业科学院蔬菜花卉研究所 | 一种生物组织自动脱水透明系统 |
| CN106979878B (zh) * | 2017-05-09 | 2023-12-15 | 贵阳德漫多医疗科技有限公司 | 一种组织病理标本处理系统 |
| EP3732461A1 (en) | 2017-12-29 | 2020-11-04 | F. Hoffmann-La Roche AG | Tissue sample preparation system |
| DE102019109807A1 (de) * | 2019-04-12 | 2020-10-15 | K Line Europe Gmbh | Verfahren zum wiederholten Aktivieren einer kieferorthopädischen Korrekturvorrichtung |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5782897A (en) * | 1987-06-26 | 1998-07-21 | Microwave Medical Systems, Inc. | Microwave heating apparatus for rapid tissue fixation |
| US5230865A (en) * | 1989-09-08 | 1993-07-27 | Cem Corporation | Ventable rupture diaphragm-protected container for heating contained materials by microwave radiation |
| US5355439A (en) * | 1991-08-05 | 1994-10-11 | Bio Tek Instruments | Method and apparatus for automated tissue assay |
| US5696887A (en) * | 1991-08-05 | 1997-12-09 | Biotek Solutions, Incorporated | Automated tissue assay using standardized chemicals and packages |
| JPH06196257A (ja) * | 1992-12-24 | 1994-07-15 | Hitachi Ltd | 電子レンジ |
| US5532462A (en) * | 1994-04-29 | 1996-07-02 | Communications & Power Industries | Method of and apparatus for heating a reaction vessel with microwave energy |
| ES2119535T3 (es) * | 1996-08-02 | 1998-10-01 | Milestone Srl | Procedimiento para procesar muestras organicas. |
| JPH10172751A (ja) * | 1996-12-04 | 1998-06-26 | Matsushita Electric Ind Co Ltd | 電子レンジ |
| DE19652339A1 (de) * | 1996-12-17 | 1998-06-18 | Microm Laborgeraete Gmbh | Vorrichtung zur Behandlung von Objekten |
| US6207408B1 (en) * | 1997-08-20 | 2001-03-27 | University Of Miami | High quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation method |
| JPH11221160A (ja) * | 1998-02-10 | 1999-08-17 | Takata Kk | 保温器 |
-
2000
- 2000-12-14 EP EP00990212A patent/EP1238256B1/en not_active Expired - Lifetime
- 2000-12-14 AU AU20940/01A patent/AU2094001A/en not_active Abandoned
- 2000-12-14 US US09/735,914 patent/US20010043884A1/en not_active Abandoned
- 2000-12-14 AU AU27271/01A patent/AU773429B2/en not_active Expired
- 2000-12-14 AT AT00990212T patent/ATE331946T1/de not_active IP Right Cessation
- 2000-12-14 WO PCT/US2000/033760 patent/WO2001044783A1/en not_active Ceased
- 2000-12-14 JP JP2001545824A patent/JP2003517601A/ja active Pending
- 2000-12-14 DK DK00990212T patent/DK1238256T3/da active
- 2000-12-14 WO PCT/US2000/033761 patent/WO2001044784A1/en not_active Ceased
- 2000-12-14 DE DE60029129T patent/DE60029129T2/de not_active Expired - Lifetime
- 2000-12-14 CA CA002394194A patent/CA2394194C/en not_active Expired - Lifetime
- 2000-12-14 KR KR1020027007636A patent/KR100743727B1/ko not_active Expired - Fee Related
- 2000-12-14 ES ES00990212T patent/ES2263509T3/es not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011055120A1 (de) * | 2011-04-20 | 2012-10-25 | Leica Biosystems Nussloch Gmbh | Verfahren zur Ausführung bei der Verarbeitung zumindest einer histologischen Probe |
| US8709749B2 (en) | 2011-04-20 | 2014-04-29 | Leica Biosystems Nussloch Gmbh | Method for execution upon processing of at least one histological sample |
| US9121796B2 (en) | 2011-04-20 | 2015-09-01 | Leica Biosystems Nussloch Gmbh | Method for execution upon processing of at least one histological sample |
| DE102011055120B4 (de) * | 2011-04-20 | 2016-04-14 | Leica Biosystems Nussloch Gmbh | Verfahren zur Verarbeitung zumindest einer histologischen Probe und Vorrichtung zum Behandeln einer histologischen Probe. |
| DE102021105932A1 (de) | 2021-03-11 | 2022-09-15 | Leica Biosystems Nussloch Gmbh | Verfahren zur Gewebeprozessierung und Gewebeprozessor |
| DE102021105932B4 (de) | 2021-03-11 | 2023-02-16 | Leica Biosystems Nussloch Gmbh | Verfahren zur Gewebeprozessierung und Gewebeprozessor |
Also Published As
| Publication number | Publication date |
|---|---|
| KR100743727B1 (ko) | 2007-07-30 |
| WO2001044784A1 (en) | 2001-06-21 |
| WO2001044783A1 (en) | 2001-06-21 |
| CA2394194C (en) | 2009-08-25 |
| EP1238256A1 (en) | 2002-09-11 |
| CA2394194A1 (en) | 2001-06-21 |
| JP2003517601A (ja) | 2003-05-27 |
| EP1238256B1 (en) | 2006-06-28 |
| KR20020082836A (ko) | 2002-10-31 |
| DE60029129D1 (de) | 2006-08-10 |
| ES2263509T3 (es) | 2006-12-16 |
| US20010043884A1 (en) | 2001-11-22 |
| AU2094001A (en) | 2001-06-25 |
| AU2727101A (en) | 2001-06-25 |
| AU773429B2 (en) | 2004-05-27 |
| DK1238256T3 (da) | 2006-10-30 |
| ATE331946T1 (de) | 2006-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60029129T2 (de) | Schnelle gewebeaufbereitungsvorrichtung | |
| US6793890B2 (en) | Rapid tissue processor | |
| JP4527122B2 (ja) | 組織処理の簡素化 | |
| US6797928B2 (en) | Method and apparatus for the rapid decalcification and fixation of mineralized tissues | |
| JP6189306B2 (ja) | 凍結切片の代用としての超迅速診断用組織調製法 | |
| EP0584484A1 (de) | Verfahren und Einrichtung zum Desinfizieren von Knochentransplantaten, insbesondere von humanen Spongiosa-Transplantaten | |
| EP0318924B1 (de) | Auftau- und Temperiervorrichtung für medizinische Produkte | |
| DE3325195A1 (de) | Verfahren zur temperierung einer fluessigkeit | |
| DE60306225T2 (de) | Verfahren zum modellieren des Sterilisationsgrades in Nahrungsmitteleinrichtungen | |
| DE102007046217B4 (de) | Vorrichtung zur Mikrowellen-gestützten Präparation von Proben | |
| DE202020106563U1 (de) | Auftauvorrichtung zum Auftauen eines Substrats | |
| JP7688706B2 (ja) | 可変電力冷マイクロ波組織処理装置 | |
| EP2927664A1 (de) | Vorrichtung zur gleichzeitigen Präparation einer Mehrzahl von Frischgewebeschnitten sowie ein Durchführungsverfahren | |
| DE102014224714B4 (de) | Verfahren und Einrichtung zum Aufbereiten von chirurgischen Instrumenten | |
| EP3339831A1 (de) | Vorrichtung für das kühlen von biologischen und/oder medizinischen proben | |
| EP0923946A2 (de) | Verfahren zum Erzeugen einer desinfizierenden heissen Atmosphäre sowie Vorrichtung | |
| DE102004013834A1 (de) | Verfahren und Vorrichtung zur Behandlung von Milch, insbesondere von Muttermilch | |
| AU2015227390A1 (en) | Ultra-rapid diagnostic tissue preparation as an alternative to frozen section | |
| US20040037751A1 (en) | Electromagnetic control of pathogens in poultry production facilities | |
| Decalcification | Useful Methods for Research and Clinical | |
| Nasiri | Experience With an Automated Microwave-Assisted Rapid Tissue Processing Method | |
| DE2261125A1 (de) | Apparat zur vorbehandlung von gewebeproben fuer elektromikroskopische untersuchung | |
| CH677311A5 (en) | Monitoring cooking process in prepn. of fried foods, esp. potato chips - where cooking oil is prepd. in number of prepn. tanks and is pumped into cooking vessel | |
| DE2843784A1 (de) | Verfahren und vorrichtung zur temperaturbehandlung eines gegenstandes | |
| DE19725968A1 (de) | Gefrierschnitte von physikalisch stabilisierten Probeexzisionen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: THE UNIVERSITY OF MIAMI, MIAMI, FLA., US |