DE60027578D1 - Verfahren zum Nachweis von Bioanalyten mittels metallische Nanohüllen - Google Patents

Verfahren zum Nachweis von Bioanalyten mittels metallische Nanohüllen

Info

Publication number
DE60027578D1
DE60027578D1 DE60027578T DE60027578T DE60027578D1 DE 60027578 D1 DE60027578 D1 DE 60027578D1 DE 60027578 T DE60027578 T DE 60027578T DE 60027578 T DE60027578 T DE 60027578T DE 60027578 D1 DE60027578 D1 DE 60027578D1
Authority
DE
Germany
Prior art keywords
core
nanoshells
particles
shell
metal shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027578T
Other languages
English (en)
Other versions
DE60027578T2 (de
Inventor
L West
L Halas
J Oldenburg
D Averitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William Marsh Rice University
Original Assignee
William Marsh Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William Marsh Rice University filed Critical William Marsh Rice University
Application granted granted Critical
Publication of DE60027578D1 publication Critical patent/DE60027578D1/de
Publication of DE60027578T2 publication Critical patent/DE60027578T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/82—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/84—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by UV- or VIS- data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/10—Particle morphology extending in one dimension, e.g. needle-like
    • C01P2004/12—Particle morphology extending in one dimension, e.g. needle-like with a cylindrical shape
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/30—Particle morphology extending in three dimensions
    • C01P2004/32—Spheres
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/30—Particle morphology extending in three dimensions
    • C01P2004/38—Particle morphology extending in three dimensions cube-like
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/54—Particles characterised by their aspect ratio, i.e. the ratio of sizes in the longest to the shortest dimension
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/62—Submicrometer sized, i.e. from 0.1-1 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60027578T 1999-07-16 2000-07-14 Verfahren zum Nachweis von Bioanalyten unter Verwendung metallischer Nanohüllen Expired - Lifetime DE60027578T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14413699P 1999-07-16 1999-07-16
US144136P 1999-07-16
PCT/US2000/019375 WO2001006257A1 (en) 1999-07-16 2000-07-14 Metal nanoshells for biosensing applications

Publications (2)

Publication Number Publication Date
DE60027578D1 true DE60027578D1 (de) 2006-06-01
DE60027578T2 DE60027578T2 (de) 2007-01-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027578T Expired - Lifetime DE60027578T2 (de) 1999-07-16 2000-07-14 Verfahren zum Nachweis von Bioanalyten unter Verwendung metallischer Nanohüllen

Country Status (6)

Country Link
EP (1) EP1210600B1 (de)
JP (2) JP2003504642A (de)
AT (1) ATE324587T1 (de)
CA (1) CA2377722A1 (de)
DE (1) DE60027578T2 (de)
WO (1) WO2001006257A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5074652B2 (ja) 2000-02-08 2012-11-14 ライスユニバーシティ 治療法および診断法において使用される光学活性なナノ粒子
US6707548B2 (en) 2001-02-08 2004-03-16 Array Bioscience Corporation Systems and methods for filter based spectrographic analysis
JP4772273B2 (ja) * 2001-03-09 2011-09-14 福岡 隆夫 物質の分析方法
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
WO2002096262A2 (en) * 2001-05-25 2002-12-05 Northwestern University Non-alloying core shell nanoparticles
DE10131173C2 (de) * 2001-06-29 2003-12-04 Itn Nanovation Gmbh Verfahren zur Herstellung von Kern-Hülle-Teilchen und deren Verwendung
WO2004003508A2 (en) * 2002-06-28 2004-01-08 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
DK1593091T3 (da) 2003-01-25 2013-10-28 Seno Medical Instr Inc Optoakustisk afbildning med høj kontrast ved anvendelse af ikke-sfæriske nanopartikler
CN1780729A (zh) * 2003-02-25 2006-05-31 曼弗雷德·R·库赫奈利 吸收电磁能量的包覆纳米颗粒
CA2557847A1 (en) * 2003-02-25 2005-03-17 Xmx Corporation Encapsulated nanoparticles for the absorption of electromagnetic energy in ultraviolet range
CN1514243A (zh) * 2003-04-30 2004-07-21 成都夸常科技有限公司 对目标物进行定性和/或定量分析的方法、装置和标记物及检测试剂盒
EP1624306A4 (de) * 2003-04-30 2008-12-24 Chengdu Kuachang Medical Ind L Zur trennung oder analyse verwendete nanostrukturen enthaltende vorrichtung sowie herstellung und anwendung davon
IL156626A (en) * 2003-06-24 2009-12-24 Yeda Res & Dev System for selective cell destruction
JP2005195441A (ja) * 2004-01-07 2005-07-21 Fuji Photo Film Co Ltd ラマン分光方法および装置並びにラマン分光用デバイス
JP5502279B2 (ja) * 2004-10-28 2014-05-28 エコー セラピューティクス， インコーポレイテッド ヒドロゲルを使用した検体のサンプリングおよび分析のためのシステムおよび方法
US7599066B2 (en) 2005-06-01 2009-10-06 Canon Kabushiki Kaisha Localized plasmon resonance sensor
EP1940295A4 (de) * 2005-10-24 2010-01-13 Bradley W Wait Resonante nanostrukturen und verwendungsverfahren dafür
JP2009524834A (ja) * 2006-01-27 2009-07-02 オクソニカ・インコーポレーテッド 被包検出様式を用いた側方流動イムノアッセイ
EP2013608A4 (de) * 2006-05-01 2011-07-06 Fujirebio Kk Mit metallischem überzug verkapselte nichtmetallische leuchtstoffpartikel
KR20100061603A (ko) * 2008-11-29 2010-06-08 한국전자통신연구원 바이오 물질 감지용 나노 입자 및 이를 이용한 바이오 센서
WO2011038335A1 (en) * 2009-09-25 2011-03-31 Immunolight, Llc Up and down conversion systems for improved solar cell performance or other energy conversion
ES2359411B1 (es) * 2009-10-19 2012-04-03 Universidad De Zaragoza Método de autenticación de objetos.
KR101247610B1 (ko) * 2009-12-11 2013-03-26 서울대학교산학협력단 라만 활성분자가 나노입자 이합체의 접합부에 위치한 이합체 코어쉘 나노 입자, 이의 용도 및 이의 제조방법
US20130196915A1 (en) * 2010-01-23 2013-08-01 Yong Wang Affinity hydrogels for controlled protein release
ES2618869T3 (es) * 2010-03-22 2017-06-22 Sicpa Holding Sa Una nanoetiqueta de SERS de longitud de onda selectiva
EP2608762B2 (de) 2010-08-27 2020-05-13 Sienna Biopharmaceuticals, Inc. Zusammensetzungen und verfahren für gezielte wärmemodulation
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
US10994992B2 (en) 2011-01-20 2021-05-04 Technion Research & Development Foundation Limited Method and system for manipulating a cell
WO2012149026A2 (en) * 2011-04-25 2012-11-01 The Research Foundation Of State University Of New York Spectral modification
US9150413B2 (en) * 2011-05-13 2015-10-06 Imec Waveguide-integrated plasmonic resonator for integrated SERS measurements
JP5762225B2 (ja) * 2011-09-08 2015-08-12 新留　康郎 銀シェル金ナノロッドを用いる分析方法
JP6325552B2 (ja) 2012-10-11 2018-05-16 ナノコンポジックス，インコーポレイテッド 銀ナノプレート組成物および方法
CN103808706A (zh) * 2012-11-06 2014-05-21 厦门大学 一种含针孔的壳层纳米粒子拉曼光谱检测增强剂及应用该增强剂进行拉曼光谱检测的方法
DE102013008104A1 (de) * 2013-05-14 2014-11-20 Laser-Laboratorium Göttingen e.V. SERS-Substrat
DE102013106432A1 (de) * 2013-06-20 2014-12-24 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Optische Indikator-Einheit und Vorrichtung und Verfahren zur Bestimmung einer physikalisch-chemischen Eigenschaft eines Prozessmediums in einer prozesstechnischen Anlage
US10359366B2 (en) 2013-08-23 2019-07-23 Ukon Craft Science Ltd. Substrate for surface enhanced Raman scattering spectroscopy and devices using same
WO2016051666A1 (ja) * 2014-09-30 2016-04-07 富士フイルム株式会社 炭酸ガスセンシング用の光電場増強デバイス
US11111396B2 (en) * 2014-10-17 2021-09-07 C3 Nano, Inc. Transparent films with control of light hue using nanoscale colorants
KR102127146B1 (ko) * 2017-08-08 2020-06-26 사회복지법인 삼성생명공익재단 플라즈모닉 효과를 이용한 질병의 진단에 필요한 정보 제공 방법 및 질병 진단용 슬라이드
CN110554018A (zh) * 2018-05-31 2019-12-10 上海市刑事科学技术研究院 检测水溶液中4-溴甲卡西酮的表面增强拉曼材料及其制备方法
JP7079923B2 (ja) * 2018-07-18 2022-06-03 公立大学法人名古屋市立大学 Ｓｅｒｓ測定用材料及びその製造方法
CN111375759B (zh) * 2018-12-28 2021-10-01 同方威视技术股份有限公司 一种拉曼纳米增强材料及其制备方法和应用
CN110849863B (zh) * 2019-10-15 2020-11-24 中国人民解放军第二军医大学 一种检测适配体与配体小分子结合过程中构象改变的方法
CN114942240B (zh) * 2022-05-30 2022-12-13 武汉太赫光学科技有限公司 上转换拉曼传感器及应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5023139A (en) * 1989-04-04 1991-06-11 Research Corporation Technologies, Inc. Nonlinear optical materials
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
IL100866A (en) * 1991-02-06 1995-10-31 Igen Inc Luminescence test method and device based on magnetic tiny particles, containing many magnets
USH1447H (en) * 1992-11-20 1995-06-06 E. I. Du Pont De Nemours And Company Coated silica shells
JPH07146295A (ja) * 1993-11-19 1995-06-06 Kyoto Daiichi Kagaku:Kk ラマン分光測定による免疫分析方法及び装置
JP2965502B2 (ja) * 1996-02-20 1999-10-18 株式会社京都第一科学 表面増強ラマン散乱測定による分析方法
DE69737598T2 (de) * 1996-07-29 2007-12-27 Nanosphere Inc., Skokie Nanopartikel mit daran angehefteten oligonukleotiden sowie deren verwendungen
US5898004A (en) * 1996-11-06 1999-04-27 University Of Pittsburgh Of The Commonwealth System Of Higher Education Polymerized crystalline colloidal array sensors
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
US6344272B1 (en) * 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
DE60044135D1 (de) * 1999-07-16 2010-05-20 Univ Wm Marsh Rice Temperaturabhängiges polymer/nanohüllen-komposite für photothermische modulierte arzneimittelabgabe

Also Published As

Publication number Publication date
DE60027578T2 (de) 2007-01-25
EP1210600A4 (de) 2003-05-21
WO2001006257A8 (en) 2001-11-29
ATE324587T1 (de) 2006-05-15
EP1210600A1 (de) 2002-06-05
JP2010230679A (ja) 2010-10-14
EP1210600B1 (de) 2006-04-26
JP2003504642A (ja) 2003-02-04
WO2001006257A1 (en) 2001-01-25
CA2377722A1 (en) 2001-01-25

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