DE60018052D1 - Vergleichende fluoreszenz-hybridisierung auf oligonukleotid mikroarrays - Google Patents
Vergleichende fluoreszenz-hybridisierung auf oligonukleotid mikroarraysInfo
- Publication number
- DE60018052D1 DE60018052D1 DE60018052T DE60018052T DE60018052D1 DE 60018052 D1 DE60018052 D1 DE 60018052D1 DE 60018052 T DE60018052 T DE 60018052T DE 60018052 T DE60018052 T DE 60018052T DE 60018052 D1 DE60018052 D1 DE 60018052D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- acid sequences
- oligonucleotide microarrays
- fluorescence hybridization
- solid surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000009396 hybridization Methods 0.000 title abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- 230000000052 comparative effect Effects 0.000 title 1
- 238000002493 microarray Methods 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 206010008805 Chromosomal abnormalities Diseases 0.000 abstract 1
- 208000031404 Chromosome Aberrations Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000013507 mapping Methods 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/302,056 US6465182B1 (en) | 1999-04-29 | 1999-04-29 | Comparative fluorescence hybridization to oligonucleotide microarrays |
US302056 | 1999-04-29 | ||
PCT/US2000/011433 WO2000066779A1 (en) | 1999-04-29 | 2000-04-28 | Comparative fluorescence hybridization to oligonucleotide microarrays |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60018052D1 true DE60018052D1 (de) | 2005-03-17 |
DE60018052T2 DE60018052T2 (de) | 2006-05-18 |
Family
ID=23166074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60018052T Expired - Lifetime DE60018052T2 (de) | 1999-04-29 | 2000-04-28 | Vergleichende fluoreszenz-hybridisierung auf oligonukleotid mikroarrays |
Country Status (7)
Country | Link |
---|---|
US (1) | US6465182B1 (de) |
EP (1) | EP1173621B1 (de) |
AT (1) | ATE288963T1 (de) |
CA (1) | CA2369878C (de) |
DE (1) | DE60018052T2 (de) |
ES (1) | ES2235882T3 (de) |
WO (1) | WO2000066779A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU753505B2 (en) * | 1997-10-30 | 2002-10-17 | Cold Spring Harbor Laboratory | Probe arrays and methods of using probe arrays for distinguishing DNA |
US20030087231A1 (en) * | 2000-05-19 | 2003-05-08 | Albertson Donna G. | Methods and compositions for preparation of a polynucleotide array |
KR100509217B1 (ko) * | 2000-11-13 | 2005-08-18 | 도요 고한 가부시키가이샤 | 하이브리드 형성용 담체 및 하이브리드의 고정화 방법 |
DK1436404T3 (da) * | 2001-09-19 | 2010-03-08 | Alexion Pharma Inc | Manipulerede templates og deres anvendelse i single-primer amplifikation |
US7414111B2 (en) | 2001-09-19 | 2008-08-19 | Alexion Pharmaceuticals, Inc. | Engineered templates and their use in single primer amplification |
US20030186220A1 (en) * | 2002-03-28 | 2003-10-02 | Jizhong Zhou | Detecting microorganisms using whole genomic DNA or RNA microarray |
US9388459B2 (en) * | 2002-06-17 | 2016-07-12 | Affymetrix, Inc. | Methods for genotyping |
US7822555B2 (en) | 2002-11-11 | 2010-10-26 | Affymetrix, Inc. | Methods for identifying DNA copy number changes |
US8232055B2 (en) * | 2002-12-23 | 2012-07-31 | Agilent Technologies, Inc. | Comparative genomic hybridization assays using immobilized oligonucleotide features and compositions for practicing the same |
US20040166518A1 (en) * | 2003-01-02 | 2004-08-26 | The Regents Of The University Of California | Multilabeling mouse FISH assay for detecting structural and numerical chromosomal abnormalities |
CA2526810A1 (en) * | 2003-05-23 | 2005-04-21 | Cold Spring Harbor Laboratory | Virtual representations of nucleotide sequences |
US7211384B2 (en) | 2003-05-28 | 2007-05-01 | Agilent Technologies, Inc. | Comparative genomic hybridization assays using immobilized oligonucleotide targets with initially small sample sizes and compositions for practicing the same |
US7108979B2 (en) * | 2003-09-03 | 2006-09-19 | Agilent Technologies, Inc. | Methods to detect cross-contamination between samples contacted with a multi-array substrate |
US20050147975A1 (en) * | 2003-12-24 | 2005-07-07 | Schembri Carol T. | Methods and compositions for amplification of genomic DNA |
WO2005079474A2 (en) * | 2004-02-17 | 2005-09-01 | The Regents Of The University Of California | Detection of nucleic acid sequence differences by comparative genomic hybridization |
US20070031883A1 (en) * | 2004-03-04 | 2007-02-08 | Kincaid Robert H | Analyzing CGH data to identify aberrations |
US8321138B2 (en) * | 2005-07-29 | 2012-11-27 | Agilent Technologies, Inc. | Method of characterizing quality of hybridized CGH arrays |
US20050233339A1 (en) * | 2004-04-20 | 2005-10-20 | Barrett Michael T | Methods and compositions for determining the relationship between hybridization signal of aCGH probes and target genomic DNA copy number |
WO2005113834A2 (en) * | 2004-05-20 | 2005-12-01 | Quest Diagnostics Investments Incorporated | Single label comparative hybridization |
CA2568413A1 (en) * | 2004-05-28 | 2005-12-15 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
US20060035258A1 (en) * | 2004-08-06 | 2006-02-16 | Affymetrix, Inc. | Methods for identifying DNA copy number changes |
US20070099227A1 (en) * | 2004-10-12 | 2007-05-03 | Curry Bo U | Significance analysis using data smoothing with shaped response functions |
US20060078899A1 (en) * | 2004-10-12 | 2006-04-13 | Scheffer Alicia F | Methods and compositions for reducing label variation in array-based comparative genome hybridization assays |
US20060080043A1 (en) * | 2004-10-12 | 2006-04-13 | Sampas Nicholas M | Comparative genomic hybridization significance analysis using data smoothing with shaped response functions |
US20060110744A1 (en) | 2004-11-23 | 2006-05-25 | Sampas Nicolas M | Probe design methods and microarrays for comparative genomic hybridization and location analysis |
US20070020654A1 (en) * | 2005-05-19 | 2007-01-25 | Affymetrix, Inc. | Methods and kits for preparing nucleic acid samples |
ATE524564T1 (de) | 2005-06-03 | 2011-09-15 | Beacon Biotechnology Llc | Chemilumineszenz-nukleinsäuretest |
WO2007020786A1 (ja) | 2005-08-12 | 2007-02-22 | Fuso Pharmaceutical Industries, Ltd. | 栄養外胚葉細胞特異的遺伝子導入法 |
US20070048743A1 (en) * | 2005-08-26 | 2007-03-01 | Sampas Nicholas M | Methods and compositions for assessing candidate aCGH probe nucleic acids |
US20070087355A1 (en) * | 2005-10-14 | 2007-04-19 | Barrett Michael T | Comparative genomic hybridization assays and compositions for practicing the same |
US11306351B2 (en) | 2005-12-21 | 2022-04-19 | Affymetrix, Inc. | Methods for genotyping |
US20080090236A1 (en) * | 2006-10-13 | 2008-04-17 | Yakhini Zohar H | Methods and systems for identifying tumor progression in comparative genomic hybridization data |
US20080102453A1 (en) * | 2006-10-31 | 2008-05-01 | Jayati Ghosh | Methods and systems and analysis of CGH data |
US20080207960A1 (en) * | 2007-02-28 | 2008-08-28 | Eric Lin | Methods, compositions, and kits for post-hybridization processing of arrays |
US8200440B2 (en) | 2007-05-18 | 2012-06-12 | Affymetrix, Inc. | System, method, and computer software product for genotype determination using probe array data |
WO2011011426A2 (en) | 2009-07-20 | 2011-01-27 | Bar Harbor Biotechnology, Inc. | Methods for assessing disease risk |
US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
CN107111692B (zh) | 2014-10-10 | 2021-10-29 | 生命科技股份有限公司 | 用于计算经校正扩增子覆盖度的方法、系统及计算机可读媒体 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE205542T1 (de) | 1992-03-04 | 2001-09-15 | Univ California | Vergleichende genomhybridisierung |
US5830645A (en) * | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
-
1999
- 1999-04-29 US US09/302,056 patent/US6465182B1/en not_active Expired - Lifetime
-
2000
- 2000-04-28 WO PCT/US2000/011433 patent/WO2000066779A1/en active IP Right Grant
- 2000-04-28 DE DE60018052T patent/DE60018052T2/de not_active Expired - Lifetime
- 2000-04-28 AT AT00930197T patent/ATE288963T1/de not_active IP Right Cessation
- 2000-04-28 EP EP00930197A patent/EP1173621B1/de not_active Expired - Lifetime
- 2000-04-28 CA CA002369878A patent/CA2369878C/en not_active Expired - Lifetime
- 2000-04-28 ES ES00930197T patent/ES2235882T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2000066779A1 (en) | 2000-11-09 |
DE60018052T2 (de) | 2006-05-18 |
ES2235882T3 (es) | 2005-07-16 |
EP1173621A4 (de) | 2002-10-09 |
CA2369878A1 (en) | 2000-11-09 |
CA2369878C (en) | 2009-12-08 |
US6465182B1 (en) | 2002-10-15 |
ATE288963T1 (de) | 2005-02-15 |
EP1173621B1 (de) | 2005-02-09 |
EP1173621A1 (de) | 2002-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |