DE60015371D1 - Verfahren zur herstellung von n-[(aliphatisch oder aromatisch)carbonyl]-2-aminoacetamid-verbindungen und deren cyclisierung - Google Patents

Verfahren zur herstellung von n-[(aliphatisch oder aromatisch)carbonyl]-2-aminoacetamid-verbindungen und deren cyclisierung

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Publication number
DE60015371D1
DE60015371D1 DE60015371T DE60015371T DE60015371D1 DE 60015371 D1 DE60015371 D1 DE 60015371D1 DE 60015371 T DE60015371 T DE 60015371T DE 60015371 T DE60015371 T DE 60015371T DE 60015371 D1 DE60015371 D1 DE 60015371D1
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carbonyl
aliphatic
aromatic
cyclization
producing
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DE60015371T
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DE60015371T2 (de
Inventor
Christopher Hulme
George C Morton
Joseph M Salvino
Richard F Labaudiniere
Helen J Mason
Matthew M Morrissette
Liang Ma
Marie-P Cherrier
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Aventis Pharmaceuticals Inc
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Aventis Pharmaceuticals Inc
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

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  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
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DE60015371T 1999-08-04 2000-08-03 Verfahren zur herstellung von n-[(aliphatisch oder aromatisch)carbonyl]-2-aminoacetamid-verbindungen und deren cyclisierung Expired - Lifetime DE60015371T2 (de)

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US09/368,213 US6492553B1 (en) 1998-01-29 1999-08-04 Methods for preparing N-[(aliphatic or aromatic)carbonyl)]-2-aminoaetamide compounds and for cyclizing such compounds
US368213 1999-08-04
PCT/US2000/021257 WO2001010799A1 (en) 1999-08-04 2000-08-03 Methods for preparing n-[(aliphatic or aromatic)carbonyl)]-2-aminoacetamide compounds and for cyclizing such compounds

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ATE280744T1 (de) 2004-11-15
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HK1046897A1 (en) 2003-01-30
AU6757400A (en) 2001-03-05
WO2001010799A1 (en) 2001-02-15
ES2230143T3 (es) 2005-05-01
HK1046897B (zh) 2005-04-15
US6492553B1 (en) 2002-12-10
DE60015371T2 (de) 2005-12-29

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