DE60014919T2 - Peptidantagonisten des faktors viia - Google Patents

Peptidantagonisten des faktors viia Download PDF

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Publication number
DE60014919T2
DE60014919T2 DE60014919T DE60014919T DE60014919T2 DE 60014919 T2 DE60014919 T2 DE 60014919T2 DE 60014919 T DE60014919 T DE 60014919T DE 60014919 T DE60014919 T DE 60014919T DE 60014919 T2 DE60014919 T2 DE 60014919T2
Authority
DE
Germany
Prior art keywords
xaa
amino acid
fviia
peptide
trp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60014919T
Other languages
German (de)
English (en)
Other versions
DE60014919D1 (de
Inventor
S. Mark DENNIS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE60014919D1 publication Critical patent/DE60014919D1/de
Publication of DE60014919T2 publication Critical patent/DE60014919T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60014919T 1999-08-06 2000-08-04 Peptidantagonisten des faktors viia Expired - Fee Related DE60014919T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14762799P 1999-08-06 1999-08-06
US147627P 1999-08-06
US15031599P 1999-08-23 1999-08-23
US150315P 1999-08-23
PCT/US2000/021296 WO2001010892A2 (fr) 1999-08-06 2000-08-04 ANTAGONISTE DU FVIIa

Publications (2)

Publication Number Publication Date
DE60014919D1 DE60014919D1 (de) 2004-11-18
DE60014919T2 true DE60014919T2 (de) 2005-10-13

Family

ID=26845071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60014919T Expired - Fee Related DE60014919T2 (de) 1999-08-06 2000-08-04 Peptidantagonisten des faktors viia

Country Status (8)

Country Link
US (1) US20040077547A1 (fr)
EP (1) EP1203014B1 (fr)
JP (1) JP2003512303A (fr)
AT (1) ATE279437T1 (fr)
AU (1) AU783087B2 (fr)
CA (1) CA2380633A1 (fr)
DE (1) DE60014919T2 (fr)
WO (1) WO2001010892A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158615A0 (en) * 2001-05-02 2004-05-12 Novo Nordisk As Modified factor vii in treatment of acute lung injury or acute respiratory distress syndrome
US7164002B2 (en) 2002-02-06 2007-01-16 Genentech, Inc. FVIIa antagonists
EP2393828B1 (fr) 2009-02-03 2016-10-12 Amunix Operating Inc. Polypeptides recombinants étendus et compositions les comprenant
WO2011028229A1 (fr) 2009-08-24 2011-03-10 Amunix Operating Inc. Compositions de facteur ix de coagulation et leurs procédés de fabrication et d'utilisation
RS63870B1 (sr) 2012-02-15 2023-01-31 Bioverativ Therapeutics Inc Sastavi faktora viii i postupci za pravljenje i upotrebu istih
HUE043537T2 (hu) 2012-02-15 2019-08-28 Bioverativ Therapeutics Inc Rekombináns VIII faktor fehérjék
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
EP3331608A4 (fr) 2015-08-03 2019-05-01 Bioverativ Therapeutics Inc. Protéines de fusion du facteur xi et leurs méthodes de production et d'utilisation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5726506B2 (fr) * 1974-03-08 1982-06-04
US4105603A (en) * 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US5336603A (en) * 1987-10-02 1994-08-09 Genentech, Inc. CD4 adheson variants
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
GB9225845D0 (en) * 1992-12-10 1993-02-03 Nickerson Biocem Ltd Modified plants
GB9309509D0 (en) * 1993-05-07 1993-06-23 Merck Patent Gmbh Thrombin inhibitors
US5795954A (en) * 1994-03-04 1998-08-18 Genentech, Inc. Factor VIIa inhibitors from Kunitz domain proteins
ATE346928T1 (de) * 1994-10-18 2006-12-15 Dendreon Corp Aus nematoden extrahierte serinprotease- inhibitoren und die koagulation hemmende proteine
US5759954A (en) * 1994-10-20 1998-06-02 Matsushita Electric Industrial Co., Ltd. Transfer member and thermal transfer printing method
AU1023497A (en) * 1995-12-01 1997-06-27 Genentech Inc. Tissue factor - kunitz domain fusion proteins as factor viia inhibitors
WO2000004148A1 (fr) * 1998-07-15 2000-01-27 Genentech, Inc. Variantes de proteines de facteurs tissulaires presentant une affinite accrue pour le facteur de coagulation fvii/fviia
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants

Also Published As

Publication number Publication date
EP1203014B1 (fr) 2004-10-13
ATE279437T1 (de) 2004-10-15
AU783087B2 (en) 2005-09-22
US20040077547A1 (en) 2004-04-22
JP2003512303A (ja) 2003-04-02
WO2001010892A2 (fr) 2001-02-15
AU6518300A (en) 2001-03-05
CA2380633A1 (fr) 2001-02-15
EP1203014A2 (fr) 2002-05-08
DE60014919D1 (de) 2004-11-18
WO2001010892A3 (fr) 2001-08-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee