ATE279437T1 - Peptidantagonisten des faktors viia - Google Patents
Peptidantagonisten des faktors viiaInfo
- Publication number
- ATE279437T1 ATE279437T1 AT00952495T AT00952495T ATE279437T1 AT E279437 T1 ATE279437 T1 AT E279437T1 AT 00952495 T AT00952495 T AT 00952495T AT 00952495 T AT00952495 T AT 00952495T AT E279437 T1 ATE279437 T1 AT E279437T1
- Authority
- AT
- Austria
- Prior art keywords
- fviia
- fvii
- factor viia
- peptide antagonists
- block
- Prior art date
Links
- 229940012414 factor viia Drugs 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title 1
- 108010054265 Factor VIIa Proteins 0.000 abstract 5
- 108010023321 Factor VII Proteins 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 102100023804 Coagulation factor VII Human genes 0.000 abstract 3
- 229940012413 factor vii Drugs 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14762799P | 1999-08-06 | 1999-08-06 | |
| US15031599P | 1999-08-23 | 1999-08-23 | |
| PCT/US2000/021296 WO2001010892A2 (en) | 1999-08-06 | 2000-08-04 | Peptide antagonists of factor viia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE279437T1 true ATE279437T1 (de) | 2004-10-15 |
Family
ID=26845071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00952495T ATE279437T1 (de) | 1999-08-06 | 2000-08-04 | Peptidantagonisten des faktors viia |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040077547A1 (de) |
| EP (1) | EP1203014B1 (de) |
| JP (1) | JP2003512303A (de) |
| AT (1) | ATE279437T1 (de) |
| AU (1) | AU783087B2 (de) |
| CA (1) | CA2380633A1 (de) |
| DE (1) | DE60014919T2 (de) |
| WO (1) | WO2001010892A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2003134701A (ru) * | 2001-05-02 | 2005-03-27 | Ново Нордиск А/С (DK) | Модифицированный fvii при лечении ards |
| US7164002B2 (en) | 2002-02-06 | 2007-01-16 | Genentech, Inc. | FVIIa antagonists |
| SI2393828T1 (sl) | 2009-02-03 | 2017-01-31 | Amunix Operating Inc. | Podaljšani rekombinantni polipetidi in sestavki, ki jih obsegajo |
| US20110046060A1 (en) | 2009-08-24 | 2011-02-24 | Amunix Operating, Inc., | Coagulation factor IX compositions and methods of making and using same |
| CN111548418A (zh) | 2012-02-15 | 2020-08-18 | 比奥贝拉蒂治疗公司 | 因子viii组合物及其制备和使用方法 |
| NZ628014A (en) | 2012-02-15 | 2016-09-30 | Biogen Ma Inc | Recombinant factor viii proteins |
| US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
| AU2016301303B2 (en) | 2015-08-03 | 2021-10-07 | Bioverativ Therapeutics Inc. | Factor IX fusion proteins and methods of making and using same |
| WO2018102743A1 (en) | 2016-12-02 | 2018-06-07 | Bioverativ Therapeutics Inc. | Methods of treating hemophilic arthropathy using chimeric clotting factors |
| JP7763589B2 (ja) | 2018-05-18 | 2025-11-04 | バイオベラティブ セラピューティクス インコーポレイテッド | 血友病ａを処置する方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5726506B2 (de) * | 1974-03-08 | 1982-06-04 | ||
| US4105603A (en) * | 1977-03-28 | 1978-08-08 | The Salk Institute For Biological Studies | Peptides which effect release of hormones |
| US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5336603A (en) * | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
| US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US5122614A (en) * | 1989-04-19 | 1992-06-16 | Enzon, Inc. | Active carbonates of polyalkylene oxides for modification of polypeptides |
| US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
| GB9225845D0 (en) * | 1992-12-10 | 1993-02-03 | Nickerson Biocem Ltd | Modified plants |
| GB9309509D0 (en) * | 1993-05-07 | 1993-06-23 | Merck Patent Gmbh | Thrombin inhibitors |
| US5795954A (en) * | 1994-03-04 | 1998-08-18 | Genentech, Inc. | Factor VIIa inhibitors from Kunitz domain proteins |
| ES2276396T3 (es) * | 1994-10-18 | 2007-06-16 | Dendreon Corporation | Proteinas anticoagulantes e inhibidores de la serina proteasa extraidos de nematodos. |
| US5759954A (en) * | 1994-10-20 | 1998-06-02 | Matsushita Electric Industrial Co., Ltd. | Transfer member and thermal transfer printing method |
| WO1997020939A1 (en) * | 1995-12-01 | 1997-06-12 | Genentech, Inc. | TISSUE FACTOR - KUNITZ DOMAIN FUSION PROTEINS AS FACTOR VIIa INHIBITORS |
| EP1105475A1 (de) * | 1998-07-15 | 2001-06-13 | Genentech, Inc. | Proteinvarianten von gewebsfaktoren mit erhöhter affinität für koagulationsfaktor fvii/fviia |
| US20090087878A9 (en) * | 1999-05-06 | 2009-04-02 | La Rosa Thomas J | Nucleic acid molecules associated with plants |
-
2000
- 2000-08-04 AT AT00952495T patent/ATE279437T1/de not_active IP Right Cessation
- 2000-08-04 CA CA002380633A patent/CA2380633A1/en not_active Abandoned
- 2000-08-04 DE DE60014919T patent/DE60014919T2/de not_active Expired - Fee Related
- 2000-08-04 JP JP2001515700A patent/JP2003512303A/ja active Pending
- 2000-08-04 AU AU65183/00A patent/AU783087B2/en not_active Ceased
- 2000-08-04 WO PCT/US2000/021296 patent/WO2001010892A2/en not_active Ceased
- 2000-08-04 EP EP00952495A patent/EP1203014B1/de not_active Expired - Lifetime
-
2003
- 2003-08-11 US US10/639,076 patent/US20040077547A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040077547A1 (en) | 2004-04-22 |
| WO2001010892A3 (en) | 2001-08-23 |
| AU6518300A (en) | 2001-03-05 |
| WO2001010892A2 (en) | 2001-02-15 |
| DE60014919T2 (de) | 2005-10-13 |
| AU783087B2 (en) | 2005-09-22 |
| JP2003512303A (ja) | 2003-04-02 |
| DE60014919D1 (de) | 2004-11-18 |
| EP1203014A2 (de) | 2002-05-08 |
| EP1203014B1 (de) | 2004-10-13 |
| CA2380633A1 (en) | 2001-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |