DE60007990D1 - Verfahren zum nachweis von fehlpaarungen oder mutationen in nukleinsäuren - Google Patents

Verfahren zum nachweis von fehlpaarungen oder mutationen in nukleinsäuren

Info

Publication number
DE60007990D1
DE60007990D1 DE60007990T DE60007990T DE60007990D1 DE 60007990 D1 DE60007990 D1 DE 60007990D1 DE 60007990 T DE60007990 T DE 60007990T DE 60007990 T DE60007990 T DE 60007990T DE 60007990 D1 DE60007990 D1 DE 60007990D1
Authority
DE
Germany
Prior art keywords
nucleic acid
mismatches
mutations
nucleic acids
double
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60007990T
Other languages
English (en)
Other versions
DE60007990T2 (de
Inventor
Masanori Gotoh
Robert F Whittier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Bio Sciences KK
Original Assignee
Amersham Biosciences KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences KK filed Critical Amersham Biosciences KK
Publication of DE60007990D1 publication Critical patent/DE60007990D1/de
Application granted granted Critical
Publication of DE60007990T2 publication Critical patent/DE60007990T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
DE60007990T 1999-04-19 2000-04-19 Verfahren zum nachweis von fehlpaarungen oder mutationen in nukleinsäuren Expired - Fee Related DE60007990T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11110914A JP2000300265A (ja) 1999-04-19 1999-04-19 ２本鎖核酸中のミスマッチ検出方法および変異を有する核酸の検出方法、並びにミスマッチを有する２本鎖核酸の分離方法
JP11091499 1999-04-19
PCT/IB2000/000489 WO2000063691A2 (en) 1999-04-19 2000-04-19 Method for detecting mismatches or mutations in nucleic acid

Publications (2)

Publication Number Publication Date
DE60007990D1 true DE60007990D1 (de) 2004-03-04
DE60007990T2 DE60007990T2 (de) 2004-11-11

Family

ID=14547844

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60007990T Expired - Fee Related DE60007990T2 (de) 1999-04-19 2000-04-19 Verfahren zum nachweis von fehlpaarungen oder mutationen in nukleinsäuren

Country Status (7)

Country Link
EP (1) EP1192273B1 (de)
JP (2) JP2000300265A (de)
AT (1) ATE258606T1 (de)
AU (1) AU773590B2 (de)
CA (1) CA2369470A1 (de)
DE (1) DE60007990T2 (de)
WO (1) WO2000063691A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259125A1 (en) * 2003-02-26 2004-12-23 Omni Genetics, Inc. Methods, systems and apparatus for identifying genetic differences in disease and drug response
WO2005063977A1 (ja) 2003-12-25 2005-07-14 Riken 核酸の増幅法およびこれを利用した変異核酸の検出法
JP2008151771A (ja) 2006-11-22 2008-07-03 Fujifilm Corp マイクロ流体チップ
CA2622649C (en) 2007-03-09 2018-04-24 Riken Nucleic acid amplification method using primer exhibiting exciton effect
WO2009054510A1 (ja) 2007-10-25 2009-04-30 Riken 等温増幅方法およびそれに用いるｄｎａポリメラーゼ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459039A (en) * 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
US5556750A (en) * 1989-05-12 1996-09-17 Duke University Methods and kits for fractionating a population of DNA molecules based on the presence or absence of a base-pair mismatch utilizing mismatch repair systems
WO1993022457A1 (en) * 1992-04-24 1993-11-11 Massachusetts Institute Of Technology Screening for genetic variation
US6027877A (en) * 1993-11-04 2000-02-22 Gene Check, Inc. Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
CA2220951A1 (en) * 1995-02-01 1996-08-08 Research Development Foundation Detecting dna damage, measuring dna repair rates, and monitoring dna repair enzyme activity
WO1997033903A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. HUMAN MutY
CA2267642A1 (en) * 1997-07-31 1999-02-11 Yoshihide Hayashizaki Methods for detecting mutation in base sequence
US6048696A (en) * 1998-05-13 2000-04-11 Epicentre Technologies Corporation Method of identifying nucleic acid molecules

Also Published As

Publication number Publication date
WO2000063691A2 (en) 2000-10-26
JP2003517285A (ja) 2003-05-27
EP1192273B1 (de) 2004-01-28
EP1192273A2 (de) 2002-04-03
AU3982900A (en) 2000-11-02
CA2369470A1 (en) 2000-10-26
WO2000063691A3 (en) 2002-02-07
ATE258606T1 (de) 2004-02-15
AU773590B2 (en) 2004-05-27
JP2000300265A (ja) 2000-10-31
DE60007990T2 (de) 2004-11-11

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee