DE60007168D1 - Benzopyranyl-guanidin-derivate, verfahren zu deren herstellung sowie diese enthaltenden pharmazeutische zusammensetzungen - Google Patents
Benzopyranyl-guanidin-derivate, verfahren zu deren herstellung sowie diese enthaltenden pharmazeutische zusammensetzungenInfo
- Publication number
- DE60007168D1 DE60007168D1 DE60007168T DE60007168T DE60007168D1 DE 60007168 D1 DE60007168 D1 DE 60007168D1 DE 60007168 T DE60007168 T DE 60007168T DE 60007168 T DE60007168 T DE 60007168T DE 60007168 D1 DE60007168 D1 DE 60007168D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- pharmaceutical compositions
- compositions containing
- guanidine derivatives
- benzopyranyl guanidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19990045871 | 1999-10-21 | ||
KR9945871 | 1999-10-21 | ||
KR2000060467 | 2000-10-13 | ||
KR10-2000-0060467A KR100429609B1 (ko) | 1999-10-21 | 2000-10-13 | 벤조피라닐 구아니딘 유도체, 그의 제조방법 및 그를포함하는 약학적 조성물 |
PCT/KR2000/001189 WO2001029023A1 (en) | 1999-10-21 | 2000-10-20 | Benzopyranyl guanidine derivatives, process for preparation thereof, and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60007168D1 true DE60007168D1 (de) | 2004-01-22 |
DE60007168T2 DE60007168T2 (de) | 2004-12-30 |
Family
ID=36763698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60007168T Expired - Lifetime DE60007168T2 (de) | 1999-10-21 | 2000-10-20 | Benzopyranyl-guanidin-derivate, verfahren zu deren herstellung sowie diese enthaltenden pharmazeutische zusammensetzungen |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1228058B1 (de) |
JP (1) | JP3999515B2 (de) |
CN (1) | CN1229371C (de) |
AU (1) | AU1175001A (de) |
BR (1) | BR0015227B1 (de) |
CA (1) | CA2387727C (de) |
DE (1) | DE60007168T2 (de) |
ES (1) | ES2210009T3 (de) |
HK (1) | HK1051538A1 (de) |
MX (1) | MXPA02003898A (de) |
WO (1) | WO2001029023A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100492252B1 (ko) * | 2002-08-09 | 2005-05-30 | 한국화학연구원 | 이미다졸을 포함하는 이차아민으로 치환된 벤조피란유도체 및 그의 제조방법 |
KR100512486B1 (ko) * | 2003-05-28 | 2005-09-06 | 동부한농화학 주식회사 | 싸이옥소벤즈옥사졸 유도체로 치환된 벤조피란 유도체또는 약학적으로 허용되는 염, 이의 제조방법 및 이를포함하는 약학적 조성물 |
KR100545780B1 (ko) * | 2003-05-28 | 2006-01-24 | 동부한농화학 주식회사 | 벤즈이미다졸 유도체로 치환된 벤조피란 유도체 또는약학적으로 허용되는 그의 염, 이의 제조 방법 및 이를포함하는 약학적 조성물 |
EP2487171A1 (de) * | 2011-02-08 | 2012-08-15 | Université de Liège | Dihydrobenzopyran-, Thiochroman-, Tetrahydrochinolin- und Tetrahydronaphthalinderivate und ihre Verwendung in der Krebstherapie |
CA2877326A1 (en) * | 2012-06-28 | 2014-01-03 | Abbvie Inc. | Cyanoguanidines and their use as antiviral agents |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02172984A (ja) * | 1988-12-23 | 1990-07-04 | Yamanouchi Pharmaceut Co Ltd | クロマン誘導体 |
US5140031A (en) * | 1989-05-31 | 1992-08-18 | E. R. Squibb & Sons, Inc. | Pyranyl cyanoguanidine derivatives |
CA2015296C (en) * | 1989-05-31 | 2001-08-07 | Karnail Atwal | Pyranyl cyanoguanidine derivatives |
JPH05186458A (ja) * | 1991-04-26 | 1993-07-27 | Japan Tobacco Inc | 新規なベンゾピラン誘導体 |
-
2000
- 2000-10-20 BR BRPI0015227-7A patent/BR0015227B1/pt not_active IP Right Cessation
- 2000-10-20 CA CA002387727A patent/CA2387727C/en not_active Expired - Fee Related
- 2000-10-20 EP EP00973213A patent/EP1228058B1/de not_active Expired - Lifetime
- 2000-10-20 DE DE60007168T patent/DE60007168T2/de not_active Expired - Lifetime
- 2000-10-20 ES ES00973213T patent/ES2210009T3/es not_active Expired - Lifetime
- 2000-10-20 CN CNB008146551A patent/CN1229371C/zh not_active Expired - Fee Related
- 2000-10-20 AU AU11750/01A patent/AU1175001A/en not_active Abandoned
- 2000-10-20 JP JP2001531823A patent/JP3999515B2/ja not_active Expired - Fee Related
- 2000-10-20 MX MXPA02003898A patent/MXPA02003898A/es active IP Right Grant
- 2000-10-20 WO PCT/KR2000/001189 patent/WO2001029023A1/en active IP Right Grant
-
2003
- 2003-05-27 HK HK03103787A patent/HK1051538A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE60007168T2 (de) | 2004-12-30 |
CA2387727C (en) | 2008-10-14 |
CN1382134A (zh) | 2002-11-27 |
EP1228058A1 (de) | 2002-08-07 |
EP1228058B1 (de) | 2003-12-10 |
CN1229371C (zh) | 2005-11-30 |
JP3999515B2 (ja) | 2007-10-31 |
ES2210009T3 (es) | 2004-07-01 |
MXPA02003898A (es) | 2003-07-14 |
BR0015227B1 (pt) | 2011-12-27 |
WO2001029023A1 (en) | 2001-04-26 |
HK1051538A1 (en) | 2003-08-08 |
EP1228058A4 (de) | 2003-02-12 |
AU1175001A (en) | 2001-04-30 |
JP2003512367A (ja) | 2003-04-02 |
CA2387727A1 (en) | 2001-04-26 |
BR0015227A (pt) | 2002-07-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DONGBU HITEK CO., LTD., SEOUL, KR |