DE60006825D1 - Serotonerge benzofurane - Google Patents

Serotonerge benzofurane

Info

Publication number
DE60006825D1
DE60006825D1 DE60006825T DE60006825T DE60006825D1 DE 60006825 D1 DE60006825 D1 DE 60006825D1 DE 60006825 T DE60006825 T DE 60006825T DE 60006825 T DE60006825 T DE 60006825T DE 60006825 D1 DE60006825 D1 DE 60006825D1
Authority
DE
Germany
Prior art keywords
serotonerge
benzofurane
benzofurans
serotonergic
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60006825T
Other languages
English (en)
Other versions
DE60006825T2 (de
Inventor
Karin Briner
Paul Burkhart
Paul Burkholder
Eugene Cunningham
Joseph Fisher
Harlan Gritton
Darshini Jesudason
Christopher Miller
Thomas Mullaney
Robert Reinhard
Ryan Rothhaar
Craig Stevens
Larry Winneroski
Yanping Xu
Yao-Chang Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE60006825D1 publication Critical patent/DE60006825D1/de
Publication of DE60006825T2 publication Critical patent/DE60006825T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyethers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Dental Preparations (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Furan Compounds (AREA)
DE60006825T 1999-07-29 2000-07-21 Serotonerge benzofurane Expired - Fee Related DE60006825T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14618199P 1999-07-29 1999-07-29
US146181P 1999-07-29
US17260199P 1999-12-20 1999-12-20
US172601P 1999-12-20
PCT/US2000/019544 WO2001009122A2 (en) 1999-07-29 2000-07-21 Serotonergic benzofurans

Publications (2)

Publication Number Publication Date
DE60006825D1 true DE60006825D1 (de) 2004-01-08
DE60006825T2 DE60006825T2 (de) 2004-08-12

Family

ID=26843646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006825T Expired - Fee Related DE60006825T2 (de) 1999-07-29 2000-07-21 Serotonerge benzofurane

Country Status (13)

Country Link
EP (1) EP1204659B1 (de)
JP (1) JP2003506369A (de)
CN (1) CN1407982A (de)
AT (1) ATE255105T1 (de)
AU (1) AU768339B2 (de)
BR (1) BR0012751A (de)
CA (1) CA2380608A1 (de)
DE (1) DE60006825T2 (de)
DK (1) DK1204659T3 (de)
ES (1) ES2209951T3 (de)
MX (1) MXPA02000914A (de)
PT (1) PT1204659E (de)
WO (1) WO2001009122A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2428905A1 (en) 2000-11-20 2002-05-23 Biovitrum Ab PIPERAZINYLPYRAZINE COMPOUNDS FOR USE AS ANTAGONISTS OF THE SEROTONIN 5-HT2 RECEPTOR
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
WO2004000830A1 (en) 2002-06-19 2003-12-31 Biovitrum Ab Novel compounds, their use and preparation
EP2248524A3 (de) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Mittel zur prävention/behandlung von stressbedingter harninkontinenz und vorsorgeuntersuchungsverfahren dafür
EP2742936A1 (de) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Kondensierte heterocyclische Verbindung und ihre Verwendung
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
EP2510949A4 (de) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutikum für fibromyalgie
CN103601669B (zh) * 2013-05-20 2016-08-03 甘肃科瑞生物科技有限公司 一种1-叔丁氧羰基-2-甲基-4-哌啶酮的合成方法
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
KR102037494B1 (ko) 2017-12-11 2019-10-28 씨제이헬스케어 주식회사 광학활성을 갖는 피페리딘 유도체의 중간체 및 이의 제조방법
EP3733204A4 (de) 2017-12-27 2021-09-15 Takeda Pharmaceutical Company Limited Therapeutikum für belastungsinkontinenz und stuhlinkontinenz
CN110317129A (zh) * 2019-05-30 2019-10-11 杭州迈世腾药物科技有限公司 2-溴-5-甲氧基苯酚的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (de) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Neue Tetrahydropyridin- und Piperidinderivate und deren Säureadditionssalze, Verfahren zu deren Herstellung und solche enthaltende pharmazeutische Zusammensetzungen
ATE81975T1 (de) * 1984-12-21 1992-11-15 Duphar Int Res Arzneimittel mit psychotroper wirkung.
EP0398413A1 (de) * 1989-05-16 1990-11-22 Duphar International Research B.V 3,4-Dehydropiperidin-Derivate mit psychotroper Wirkung
JP2883995B2 (ja) * 1990-03-14 1999-04-19 第一製薬株式会社 ピペリジン誘導体及びその製造中間体
AU4850199A (en) * 1998-06-30 2000-01-17 Eli Lilly And Company Pyrrolidine and pyrroline derivatives having effects on serotonin related systems
EP0982304B1 (de) * 1998-06-30 2002-10-02 Eli Lilly And Company Auf serotonin-verwandte Systeme wirkende Piperidin-Derivate
WO2000000203A1 (en) * 1998-06-30 2000-01-06 Eli Lilly And Company Azepine derivatives having effects on serotonin related systems

Also Published As

Publication number Publication date
BR0012751A (pt) 2002-06-04
AU768339B2 (en) 2003-12-11
JP2003506369A (ja) 2003-02-18
EP1204659B1 (de) 2003-11-26
WO2001009122A3 (en) 2001-06-28
ATE255105T1 (de) 2003-12-15
DE60006825T2 (de) 2004-08-12
PT1204659E (pt) 2004-04-30
AU6747400A (en) 2001-02-19
WO2001009122A2 (en) 2001-02-08
CN1407982A (zh) 2003-04-02
CA2380608A1 (en) 2001-02-08
ES2209951T3 (es) 2004-07-01
DK1204659T3 (da) 2004-04-05
EP1204659A2 (de) 2002-05-15
MXPA02000914A (es) 2002-07-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee