DE60006675D1 - Verfahren zur verbesserung der fertilisierenden aktivität von spermatozoa - Google Patents

Verfahren zur verbesserung der fertilisierenden aktivität von spermatozoa

Info

Publication number
DE60006675D1
DE60006675D1 DE60006675T DE60006675T DE60006675D1 DE 60006675 D1 DE60006675 D1 DE 60006675D1 DE 60006675 T DE60006675 T DE 60006675T DE 60006675 T DE60006675 T DE 60006675T DE 60006675 D1 DE60006675 D1 DE 60006675D1
Authority
DE
Germany
Prior art keywords
spermatozoa
improving
fertilizing activity
fertilizing
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60006675T
Other languages
English (en)
Other versions
DE60006675T2 (de
Inventor
Michaela Luconi
Elisabetta Baldi
Gianni Forti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Serono SA
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of DE60006675D1 publication Critical patent/DE60006675D1/de
Publication of DE60006675T2 publication Critical patent/DE60006675T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fertilizers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60006675T 1999-07-26 2000-07-25 Verfahren zur verbesserung der fertilisierenden aktivität von spermatozoa Expired - Fee Related DE60006675T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITFI990171 1999-07-26
IT1999FI000171A IT1307787B1 (it) 1999-07-26 1999-07-26 Processo per incrementare la motilita' degli spermatozoi e spermatozoia motilita' superiore cosi' ottenuti.
PCT/EP2000/007108 WO2001007021A2 (en) 1999-07-26 2000-07-25 Process for the improvement of spermatozoa fertilization activity

Publications (2)

Publication Number Publication Date
DE60006675D1 true DE60006675D1 (de) 2003-12-24
DE60006675T2 DE60006675T2 (de) 2004-09-30

Family

ID=11353050

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006675T Expired - Fee Related DE60006675T2 (de) 1999-07-26 2000-07-25 Verfahren zur verbesserung der fertilisierenden aktivität von spermatozoa

Country Status (12)

Country Link
EP (2) EP1196153B1 (de)
JP (1) JP2003505412A (de)
AT (1) ATE254452T1 (de)
AU (1) AU777618B2 (de)
CA (1) CA2378650A1 (de)
DE (1) DE60006675T2 (de)
DK (1) DK1196153T3 (de)
ES (1) ES2206276T3 (de)
IL (1) IL147676A0 (de)
IT (1) IT1307787B1 (de)
PT (1) PT1196153E (de)
WO (1) WO2001007021A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU752985B2 (en) 1997-01-31 2002-10-03 Xy, Llc. Optical apparatus
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
WO2002043574A2 (en) 2000-11-29 2002-06-06 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
EP1531813A1 (de) * 2002-07-10 2005-05-25 Applied Research Systems ARS Holding N.V. VERWENDUNG VON vEBINDUNGEN ZUR ERHÖHUNG DER BEWEGLICHKEIT VON SPERMATOZOEN
CA2532376C (en) 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
MXPA05001654A (es) 2002-08-15 2005-10-18 Xy Inc Citometro de flujo de alta resolucion.
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
CA3074799C (en) 2003-03-28 2022-12-06 Inguran, Llc Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm
US20060263829A1 (en) 2003-05-15 2006-11-23 Evans Kenneth M Efficient haploid cell sorting flow cytometer systems
US7892725B2 (en) 2004-03-29 2011-02-22 Inguran, Llc Process for storing a sperm dispersion
CA2574499C (en) 2004-07-22 2016-11-29 Monsanto Technology Llc Process for enriching a population of sperm cells
EP1726297B1 (de) * 2005-05-23 2010-08-18 Reckitt Benckiser (UK) Limited Zusammensetzung enthalend Wortmannin und ihre topische Verwendung zur Haarwuchshemmung
CN108889345B (zh) * 2011-05-20 2020-10-09 布里格姆及妇女医院股份有限公司 游动细胞的分析和分选
CN104302761A (zh) * 2012-03-16 2015-01-21 生育创新有限公司 精细胞的处理
PT110231B (pt) 2017-08-02 2021-02-22 Universidade Do Porto Potenciadores de mtor e suas utilizações para melhorar a qualidade e função do esperma durante o armazenamento
US10470798B1 (en) 2018-11-30 2019-11-12 Ohana Biosciences, Inc. Methods for promoting fertilization

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774088A (en) * 1986-01-08 1988-09-27 The United States Of America As Represented By The Deptment Of Health And Human Services Method and additives for improving the quality and shelf life of stored blood
KR920002285B1 (ko) * 1989-10-19 1992-03-21 태평양화학 주식회사 세포 보호제
KR100292234B1 (ko) * 1992-03-09 2001-06-01 시몬스메어 래리 엠. 식물 수정능력의 조절방법
US6632789B1 (en) * 1994-04-29 2003-10-14 The United States Of America As Represented By The Secretary Of The Navy Methods for modulating T cell responses by manipulating intracellular signal transduction
JP2991620B2 (ja) * 1994-08-30 1999-12-20 科学技術振興事業団 細胞活動の制御方法
JP2000345724A (ja) * 1999-06-03 2000-12-12 Masafumi Miyamoto アミューズメント施設、アミューズメント施設用コンテナ及びアミューズメント設備の設置方法

Also Published As

Publication number Publication date
CA2378650A1 (en) 2001-02-01
ES2206276T3 (es) 2004-05-16
WO2001007021A2 (en) 2001-02-01
EP1380304A3 (de) 2004-07-07
IL147676A0 (en) 2002-08-14
AU777618B2 (en) 2004-10-21
ITFI990171A1 (it) 2001-01-26
EP1196153B1 (de) 2003-11-19
PT1196153E (pt) 2004-02-27
JP2003505412A (ja) 2003-02-12
EP1380304A2 (de) 2004-01-14
ATE254452T1 (de) 2003-12-15
DK1196153T3 (da) 2004-01-05
AU6159700A (en) 2001-02-13
WO2001007021A3 (en) 2001-12-06
IT1307787B1 (it) 2001-11-19
DE60006675T2 (de) 2004-09-30
EP1196153A2 (de) 2002-04-17
ITFI990171A0 (it) 1999-07-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LABORATOIRES SERONO S.A., COINSINS, VAUD, CH

8339 Ceased/non-payment of the annual fee