DE60000073D1 - Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten - Google Patents

Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten

Info

Publication number
DE60000073D1
DE60000073D1 DE60000073T DE60000073T DE60000073D1 DE 60000073 D1 DE60000073 D1 DE 60000073D1 DE 60000073 T DE60000073 T DE 60000073T DE 60000073 T DE60000073 T DE 60000073T DE 60000073 D1 DE60000073 D1 DE 60000073D1
Authority
DE
Germany
Prior art keywords
derivative
resulting
quinoline
tetracyclic
radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60000073T
Other languages
English (en)
Other versions
DE60000073T2 (de
Inventor
Khalid Mekouar
Yves Genisson
Stefanie Leue
E Greene
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE60000073D1 publication Critical patent/DE60000073D1/de
Publication of DE60000073T2 publication Critical patent/DE60000073T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60000073T 1999-05-28 2000-05-25 Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten Expired - Fee Related DE60000073T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9906757A FR2794123B1 (fr) 1999-05-28 1999-05-28 Preparation de derives de la camptothecine et de la nothapodytine
PCT/FR2000/001425 WO2000073305A1 (fr) 1999-05-28 2000-05-25 Preparation de derives de la camptothecine et de la nothapodytine

Publications (2)

Publication Number Publication Date
DE60000073D1 true DE60000073D1 (de) 2002-03-21
DE60000073T2 DE60000073T2 (de) 2002-08-01

Family

ID=9546112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60000073T Expired - Fee Related DE60000073T2 (de) 1999-05-28 2000-05-25 Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten

Country Status (13)

Country Link
US (1) US6500953B1 (de)
EP (1) EP1100799B1 (de)
JP (1) JP2003501355A (de)
CN (1) CN1313859A (de)
AT (1) ATE213243T1 (de)
AU (1) AU4931700A (de)
CA (1) CA2340012A1 (de)
DE (1) DE60000073T2 (de)
DK (1) DK1100799T3 (de)
ES (1) ES2172500T3 (de)
FR (1) FR2794123B1 (de)
PT (1) PT1100799E (de)
WO (1) WO2000073305A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247089A (en) * 1990-12-20 1993-09-21 North Carolina State University Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs
US6211371B1 (en) * 1993-06-30 2001-04-03 University Of Pittsburgh Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
US5475108A (en) * 1993-08-31 1995-12-12 North Carolina State University Camptothecin intermediates and method of making camptothecin and comptothecin analogs
IL117684A (en) 1995-04-07 2002-02-10 Pharmacia & Upjohn Inc Intermediates and Process for Production of History of Kempotocin (CPT-11) and Related Compounds
US6214836B1 (en) * 1995-06-06 2001-04-10 Dr. Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
DE69901379T2 (de) * 1999-03-09 2002-11-07 Sigma Tau Ind Farmaceuti Camptothecin-Derivate mit Antitumor-Wirkung

Also Published As

Publication number Publication date
PT1100799E (pt) 2002-07-31
DE60000073T2 (de) 2002-08-01
AU4931700A (en) 2000-12-18
ATE213243T1 (de) 2002-02-15
WO2000073305A1 (fr) 2000-12-07
US6500953B1 (en) 2002-12-31
CN1313859A (zh) 2001-09-19
FR2794123A1 (fr) 2000-12-01
ES2172500T3 (es) 2002-10-01
JP2003501355A (ja) 2003-01-14
FR2794123B1 (fr) 2001-07-27
CA2340012A1 (fr) 2000-12-07
EP1100799B1 (de) 2002-02-13
EP1100799A1 (de) 2001-05-23
DK1100799T3 (da) 2002-04-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee