ATE213243T1 - Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten - Google Patents

Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten

Info

Publication number
ATE213243T1
ATE213243T1 AT00931353T AT00931353T ATE213243T1 AT E213243 T1 ATE213243 T1 AT E213243T1 AT 00931353 T AT00931353 T AT 00931353T AT 00931353 T AT00931353 T AT 00931353T AT E213243 T1 ATE213243 T1 AT E213243T1
Authority
AT
Austria
Prior art keywords
derivative
resulting
quinoline
tetracyclic
radicals
Prior art date
Application number
AT00931353T
Other languages
English (en)
Inventor
Khalid Mekouar
Yves Genisson
Stefanie Leue
Andrew E Greene
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE213243T1 publication Critical patent/ATE213243T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00931353T 1999-05-28 2000-05-25 Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten ATE213243T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9906757A FR2794123B1 (fr) 1999-05-28 1999-05-28 Preparation de derives de la camptothecine et de la nothapodytine
PCT/FR2000/001425 WO2000073305A1 (fr) 1999-05-28 2000-05-25 Preparation de derives de la camptothecine et de la nothapodytine

Publications (1)

Publication Number Publication Date
ATE213243T1 true ATE213243T1 (de) 2002-02-15

Family

ID=9546112

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00931353T ATE213243T1 (de) 1999-05-28 2000-05-25 Verfahren zur herstellung von camptothecin- und nothapodyntinderivaten

Country Status (13)

Country Link
US (1) US6500953B1 (de)
EP (1) EP1100799B1 (de)
JP (1) JP2003501355A (de)
CN (1) CN1313859A (de)
AT (1) ATE213243T1 (de)
AU (1) AU4931700A (de)
CA (1) CA2340012A1 (de)
DE (1) DE60000073T2 (de)
DK (1) DK1100799T3 (de)
ES (1) ES2172500T3 (de)
FR (1) FR2794123B1 (de)
PT (1) PT1100799E (de)
WO (1) WO2000073305A1 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247089A (en) * 1990-12-20 1993-09-21 North Carolina State University Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs
US6211371B1 (en) * 1993-06-30 2001-04-03 University Of Pittsburgh Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
US5475108A (en) * 1993-08-31 1995-12-12 North Carolina State University Camptothecin intermediates and method of making camptothecin and comptothecin analogs
TW438775B (en) 1995-04-07 2001-06-07 Pharmacia & Upjohn Co Llc Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds
US6214836B1 (en) * 1995-06-06 2001-04-10 Dr. Reddy's Research Foundation Water soluble analogues of 20(S)-camptothecin
ES2175919T3 (es) * 1999-03-09 2002-11-16 Sigma Tau Ind Farmaceuti Derivados del camptothecin con actividad antitumoral.

Also Published As

Publication number Publication date
EP1100799B1 (de) 2002-02-13
PT1100799E (pt) 2002-07-31
FR2794123B1 (fr) 2001-07-27
ES2172500T3 (es) 2002-10-01
CA2340012A1 (fr) 2000-12-07
CN1313859A (zh) 2001-09-19
WO2000073305A1 (fr) 2000-12-07
JP2003501355A (ja) 2003-01-14
EP1100799A1 (de) 2001-05-23
DK1100799T3 (da) 2002-04-22
US6500953B1 (en) 2002-12-31
DE60000073D1 (de) 2002-03-21
FR2794123A1 (fr) 2000-12-01
DE60000073T2 (de) 2002-08-01
AU4931700A (en) 2000-12-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee