DE59609005D1 - Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen - Google Patents

Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen

Info

Publication number
DE59609005D1
DE59609005D1 DE59609005T DE59609005T DE59609005D1 DE 59609005 D1 DE59609005 D1 DE 59609005D1 DE 59609005 T DE59609005 T DE 59609005T DE 59609005 T DE59609005 T DE 59609005T DE 59609005 D1 DE59609005 D1 DE 59609005D1
Authority
DE
Germany
Prior art keywords
phosphinoxazoline
bidentate
chiral
ligand
transfer hydrogenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE59609005T
Other languages
English (en)
Inventor
Guenther Helmchen
Thomas Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of DE59609005D1 publication Critical patent/DE59609005D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/189—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms containing both nitrogen and phosphorus as complexing atoms, including e.g. phosphino moieties, in one at least bidentate or bridging ligand
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60—Reduction reactions, e.g. hydrogenation
    • B01J2231/64—Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/643—Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82—Metals of the platinum group
    • B01J2531/821—Ruthenium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE59609005T 1995-12-22 1996-12-19 Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen Expired - Fee Related DE59609005D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19548399A DE19548399A1 (de) 1995-12-22 1995-12-22 Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen

Publications (1)

Publication Number Publication Date
DE59609005D1 true DE59609005D1 (de) 2002-05-08

Family

ID=7781187

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19548399A Withdrawn DE19548399A1 (de) 1995-12-22 1995-12-22 Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen
DE59609005T Expired - Fee Related DE59609005D1 (de) 1995-12-22 1996-12-19 Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19548399A Withdrawn DE19548399A1 (de) 1995-12-22 1995-12-22 Rutheniumkomplexe mit einem chiralen, zweizähnigen Phosphinoxazolin-Liganden zur enantioselektiven Transferhydrierung von prochiralen Ketonen

Country Status (5)

Country Link
US (1) US5693820A (de)
EP (1) EP0780157B1 (de)
JP (1) JP3878703B2 (de)
CA (1) CA2192226C (de)
DE (2) DE19548399A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706321D0 (en) * 1997-03-26 1997-05-14 Zeneca Ltd Catalytic hydrogenation
US6255493B1 (en) 1997-11-12 2001-07-03 The Penn State Research Foundation Transition metal-catalyzed reactions based on chiral amine oxazolinyl ligands
US6472533B1 (en) * 1999-04-08 2002-10-29 The Texas A & M University System Ligands for chiral catalysis
ATE395314T1 (de) 2000-09-13 2008-05-15 Firmenich & Cie Katalytisches hydrierungsverfahren
ITMI20011758A1 (it) * 2001-08-09 2003-02-10 Ciba Sc Holding Ag Ligandi
EP2189460B1 (de) * 2007-05-04 2014-04-23 Mallinckrodt LLC Verbessertes verfahren zur herstellung von 6-alpha-hydroxy-n-alkylierten opiaten
AU2008276385B2 (en) 2007-07-17 2013-07-18 SpecGx LLC Preparation of N-alkylated opiates by reductive amination
CN102227434B (zh) * 2008-09-30 2015-02-18 马林克罗特有限公司 选择性胺化酮吗啡喃的方法
US8946419B2 (en) 2009-02-23 2015-02-03 Mallinckrodt Llc (+)-6-hydroxy-morphinan or (+)-6-amino-morphinan derivatives
EP2440561B1 (de) * 2009-06-11 2014-04-30 Mallinckrodt LLC Reduktive aminierung von 6-keto-normorphinanen durch katalytischen wasserstofftransfer
CA2764915C (en) * 2009-06-11 2017-07-11 Mallinckrodt Llc Preparation of 6-alpha-amino n-substituted morphinans by catalytic hydrogen transfer
US8431705B2 (en) 2009-09-24 2013-04-30 Mallinckrodt Llc One-pot preparation of hexahydroisoquinolines from amides
US8415474B2 (en) * 2009-09-24 2013-04-09 Mallinckrodt Llc One-pot preparation of hexahydroisoquinolines from dihydroisoquinolines
PL2718294T3 (pl) 2011-06-09 2019-04-30 SpecGx LLC Redukcyjne aminowanie 6-keto morfinanów przez katalityczne przeniesienie wodoru
KR20140063763A (ko) 2011-09-08 2014-05-27 말린크로트 엘엘씨 중간체를 단리하지 않는 알칼로이드의 제조 방법
WO2016072104A1 (ja) * 2014-11-05 2016-05-12 国立大学法人東北大学 ホスホニウム化合物およびその製造方法
WO2023153494A1 (ja) * 2022-02-14 2023-08-17 国立大学法人 東京大学 触媒、ホルムアミド類及び／又はアミン類の製造方法、ホルムアミド類及び／又はアルコール類の製造方法並びに錯体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63145291A (ja) * 1986-12-09 1988-06-17 Takasago Corp ルテニウム−ホスフイン錯体
JPH0757758B2 (ja) * 1988-10-24 1995-06-21 高砂香料工業株式会社 ルテニウム―ホスフィン錯体
KR0144567B1 (ko) * 1989-03-03 1998-07-15 오노 알버어스 카르보닐화촉매시스템
JP2796884B2 (ja) * 1990-08-30 1998-09-10 高砂香料工業株式会社 光学活性γ―ブチロラクトン誘導体の製造方法
FR2693190B1 (fr) * 1992-07-02 1994-09-23 Elf Aquitaine Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO.
DE4243030A1 (de) * 1992-12-18 1994-06-23 Basf Ag Iminverbindungen

Also Published As

Publication number Publication date
JPH09249677A (ja) 1997-09-22
EP0780157B1 (de) 2002-04-03
CA2192226C (en) 2005-04-19
JP3878703B2 (ja) 2007-02-07
US5693820A (en) 1997-12-02
DE19548399A1 (de) 1997-06-26
CA2192226A1 (en) 1997-06-23
EP0780157A1 (de) 1997-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BASF SE, 67063 LUDWIGSHAFEN, DE

8339 Ceased/non-payment of the annual fee