DE4136010A1 - Verfahren zur bestimmung einer immunologisch bindefaehigen substanz - Google Patents

Verfahren zur bestimmung einer immunologisch bindefaehigen substanz

Info

Publication number
DE4136010A1
DE4136010A1 DE4136010A DE4136010A DE4136010A1 DE 4136010 A1 DE4136010 A1 DE 4136010A1 DE 4136010 A DE4136010 A DE 4136010A DE 4136010 A DE4136010 A DE 4136010A DE 4136010 A1 DE4136010 A1 DE 4136010A1
Authority
DE
Germany
Prior art keywords
analyte
binding
conjugate
partner
macromolecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE4136010A
Other languages
German (de)
English (en)
Inventor
Arno Dr Deger
Wolfgang Dr Uhl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE4136010A priority Critical patent/DE4136010A1/de
Priority to US07/968,139 priority patent/US5278081A/en
Priority to EP92118637A priority patent/EP0540037B1/de
Priority to ES92118637T priority patent/ES2097851T3/es
Priority to DE59207717T priority patent/DE59207717D1/de
Priority to AT92118637T priority patent/ATE146595T1/de
Priority to JP4292563A priority patent/JPH0799370B2/ja
Publication of DE4136010A1 publication Critical patent/DE4136010A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/969—Multiple layering of reactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE4136010A 1991-10-31 1991-10-31 Verfahren zur bestimmung einer immunologisch bindefaehigen substanz Withdrawn DE4136010A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE4136010A DE4136010A1 (de) 1991-10-31 1991-10-31 Verfahren zur bestimmung einer immunologisch bindefaehigen substanz
US07/968,139 US5278081A (en) 1991-10-31 1992-10-29 Method for the determination of an immunologically bindable substance
EP92118637A EP0540037B1 (de) 1991-10-31 1992-10-30 Verfahren zur Bestimmung einer immunologisch bindefähigen Substanz
ES92118637T ES2097851T3 (es) 1991-10-31 1992-10-30 Procedimiento para la determinacion de una sustancia capaz de fijarse inmunologicamente.
DE59207717T DE59207717D1 (de) 1991-10-31 1992-10-30 Verfahren zur Bestimmung einer immunologisch bindefähigen Substanz
AT92118637T ATE146595T1 (de) 1991-10-31 1992-10-30 Verfahren zur bestimmung einer immunologisch bindefähigen substanz
JP4292563A JPH0799370B2 (ja) 1991-10-31 1992-10-30 免疫学的に結合可能な物質の定量方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4136010A DE4136010A1 (de) 1991-10-31 1991-10-31 Verfahren zur bestimmung einer immunologisch bindefaehigen substanz

Publications (1)

Publication Number Publication Date
DE4136010A1 true DE4136010A1 (de) 1993-08-12

Family

ID=6443887

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4136010A Withdrawn DE4136010A1 (de) 1991-10-31 1991-10-31 Verfahren zur bestimmung einer immunologisch bindefaehigen substanz
DE59207717T Expired - Fee Related DE59207717D1 (de) 1991-10-31 1992-10-30 Verfahren zur Bestimmung einer immunologisch bindefähigen Substanz

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59207717T Expired - Fee Related DE59207717D1 (de) 1991-10-31 1992-10-30 Verfahren zur Bestimmung einer immunologisch bindefähigen Substanz

Country Status (6)

Country Link
US (1) US5278081A (enExample)
EP (1) EP0540037B1 (enExample)
JP (1) JPH0799370B2 (enExample)
AT (1) ATE146595T1 (enExample)
DE (2) DE4136010A1 (enExample)
ES (1) ES2097851T3 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705353A (en) * 1995-06-07 1998-01-06 Beckman Instruments, Inc. Method of reducing interferences in assays
US20050112586A1 (en) * 2003-11-24 2005-05-26 Roland Janzen Method and composition for stabilizing liquid reagents
EP2425247A4 (en) * 2009-04-28 2013-01-23 Innovative Lab Technologies Inc IMMUNOCHROMATOGRAPHIC LATERAL FLOW TEST DEVICES
CN102621302A (zh) * 2012-03-22 2012-08-01 四川省新成生物科技有限责任公司 线性免疫法检测膜条及其制作工艺
BR112021009419A2 (pt) 2018-11-16 2021-08-17 F. Hoffmann-La Roche Ag fase sólida, método de preparação de uma fase sólida, uso, kit para determinar um analito em uma amostra, complexo e métodos para formar um complexo e para determinar um analito em uma amostra
CN112129955B (zh) * 2019-06-25 2023-04-07 迈克生物股份有限公司 睾酮检测试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134787A1 (de) * 1981-09-02 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim Creatinin-antikoerper
NZ211888A (en) * 1984-05-10 1987-08-31 Abbott Lab Biotin-antibiotin immunoassay for detecting ligands
US4870007A (en) * 1987-12-18 1989-09-26 Eastman Kodak Company Immobilized biotinylated receptor in test device, kit and method for determining a ligand
US5164299A (en) * 1990-03-20 1992-11-17 E. I. Du Pont De Nemours And Company Use of a mixture of conjugated and unconjugated solid phase binding reagent to enhance the performance of assays

Also Published As

Publication number Publication date
JPH05223817A (ja) 1993-09-03
EP0540037A3 (enExample) 1994-04-20
ATE146595T1 (de) 1997-01-15
JPH0799370B2 (ja) 1995-10-25
EP0540037B1 (de) 1996-12-18
ES2097851T3 (es) 1997-04-16
EP0540037A2 (de) 1993-05-05
US5278081A (en) 1994-01-11
DE59207717D1 (de) 1997-01-30

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination