DE3927112C1 - - Google Patents

Info

Publication number
DE3927112C1
DE3927112C1 DE3927112A DE3927112A DE3927112C1 DE 3927112 C1 DE3927112 C1 DE 3927112C1 DE 3927112 A DE3927112 A DE 3927112A DE 3927112 A DE3927112 A DE 3927112A DE 3927112 C1 DE3927112 C1 DE 3927112C1
Authority
DE
Germany
Prior art keywords
igg
solution
immunoglobulin
treated
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3927112A
Other languages
German (de)
English (en)
Inventor
Ronald Dipl.-Chem. Dr. Kotitschke
Wolfgang Dipl.-Chem. Dr. 6072 Dreieich De Stephan
Wolfgang Dipl.-Chem. Dr. 6370 Oberursel De Moeller
Detlef Dipl.-Chem. Dr. 6115 Muenster De Piechaczek
Dieter Dipl.-Chem. Dr. 6072 Dreieich De Rudnick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotest Pharma 6072 Dreieich De GmbH
Original Assignee
Biotest Pharma 6072 Dreieich De GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest Pharma 6072 Dreieich De GmbH filed Critical Biotest Pharma 6072 Dreieich De GmbH
Priority to DE3927112A priority Critical patent/DE3927112C1/de
Priority to JP1299902A priority patent/JPH0768144B2/ja
Priority to AT90114575T priority patent/ATE120963T1/de
Priority to ES90114575T priority patent/ES2070960T3/es
Priority to DE59008883T priority patent/DE59008883D1/de
Priority to EP90114575A priority patent/EP0413187B1/de
Priority to US07/561,033 priority patent/US5075425A/en
Application granted granted Critical
Publication of DE3927112C1 publication Critical patent/DE3927112C1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE3927112A 1989-08-17 1989-08-17 Expired - Fee Related DE3927112C1 (enExample)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE3927112A DE3927112C1 (enExample) 1989-08-17 1989-08-17
JP1299902A JPH0768144B2 (ja) 1989-08-17 1989-11-20 静脈内投与可能なＩｇＧ、ＩｇＡ及びＩｇＭ含有薬物の製造方法
AT90114575T ATE120963T1 (de) 1989-08-17 1990-07-30 Verfahren zur herstellung nicht modifizierter intravenös verabreichbarer igm- und/oder iga- haltige immunglobulinpräparate.
ES90114575T ES2070960T3 (es) 1989-08-17 1990-07-30 Procedimiento para la fabricacion de un medicamento conteniendo igg, iga e igm, de administracion intravenosa.
DE59008883T DE59008883D1 (de) 1989-08-17 1990-07-30 Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oder IgA-haltige Immunglobulinpräparate.
EP90114575A EP0413187B1 (de) 1989-08-17 1990-07-30 Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oder IgA-haltige Immunglobulinpräparate
US07/561,033 US5075425A (en) 1989-08-17 1990-08-01 Process for the preparation of a pharmaceutical which contains igg, iga and igm and can be administered intravenously

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927112A DE3927112C1 (enExample) 1989-08-17 1989-08-17

Publications (1)

Publication Number Publication Date
DE3927112C1 true DE3927112C1 (enExample) 1990-10-25

Family

ID=6387264

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3927112A Expired - Fee Related DE3927112C1 (enExample) 1989-08-17 1989-08-17
DE59008883T Expired - Lifetime DE59008883D1 (de) 1989-08-17 1990-07-30 Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oder IgA-haltige Immunglobulinpräparate.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE59008883T Expired - Lifetime DE59008883D1 (de) 1989-08-17 1990-07-30 Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oder IgA-haltige Immunglobulinpräparate.

Country Status (6)

Country Link
US (1) US5075425A (enExample)
EP (1) EP0413187B1 (enExample)
JP (1) JPH0768144B2 (enExample)
AT (1) ATE120963T1 (enExample)
DE (2) DE3927112C1 (enExample)
ES (1) ES2070960T3 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0893450A1 (en) * 1997-06-20 1999-01-27 Bayer Corporation Chromatographic method for high yield purification and viral inactivation of antibodies
WO2007106617A3 (en) * 2006-01-30 2008-03-20 Talecris Biotherapeutics Inc Method of treatment and prophylaxis of diseases related to amyloid deposition using igm
CN102584934A (zh) * 2012-03-19 2012-07-18 江西博雅生物制药股份有限公司 一种静注人免疫球蛋白的制备工艺

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0835880A1 (de) * 1996-10-14 1998-04-15 Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk Verfahren zur Herstellung eines IgM Präparates für die intravenöse Applikation
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
US8119138B2 (en) * 2000-05-10 2012-02-21 Signe Biopharma Inc. Anti-estrogen and immune modulator combinations for treating breast cancer
US7863011B2 (en) * 2000-05-10 2011-01-04 Signe Biopharma, Inc. Screening method for predicting susceptibility to breast cancer
US7947275B2 (en) 2000-05-10 2011-05-24 Signe Biopharma, Inc. Compositions and methods for demonstrating secretory immune system regulation of steroid hormone responsive cancer cell growth
US20030072812A1 (en) * 2001-05-10 2003-04-17 Sirbasku David A Breast cancer eradication program
FR2824568B1 (fr) * 2001-05-11 2004-04-09 Lab Francais Du Fractionnement Procede de preparation de concentres d'immunoglobulines humaines a usage therapeutique
WO2005073252A1 (en) * 2004-01-30 2005-08-11 Suomen Punainen Risti Veripalvelu Process for the manufacture of virus safe immunoglobulin
GB201006753D0 (en) 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
CN101948535B (zh) * 2010-09-27 2012-11-07 浙江大学 一种从鸡血中分离免疫球蛋白IgY的方法
FR2977893B1 (fr) * 2011-07-11 2015-02-20 Lab Francais Du Fractionnement Procede de preparation d'un concentre d'immunoglobulines polyvalentes
US9096648B2 (en) * 2011-08-19 2015-08-04 Emd Millipore Corporation Methods of reducing level of one or more impurities in a sample during protein purification
EP3275897A1 (en) 2016-07-27 2018-01-31 Biotest AG Process for preparing immunoglobulin compositions
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013901A1 (de) * 1979-01-18 1980-08-06 Biotest-Serum-Institut GmbH Verfahren zur Herstellung einer für die intravenöse Applikation geeigneten Immunglobulinlösung, die IgM in ankonzentrierter Form enthält

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3808189A (en) * 1973-03-15 1974-04-30 American Cyanamid Co Isolation of gamma globulin preparations enriched in iga and igm using polyethylene glycol
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013901A1 (de) * 1979-01-18 1980-08-06 Biotest-Serum-Institut GmbH Verfahren zur Herstellung einer für die intravenöse Applikation geeigneten Immunglobulinlösung, die IgM in ankonzentrierter Form enthält

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0893450A1 (en) * 1997-06-20 1999-01-27 Bayer Corporation Chromatographic method for high yield purification and viral inactivation of antibodies
USRE43655E1 (en) 1997-06-20 2012-09-11 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
USRE44558E1 (en) 1997-06-20 2013-10-22 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
WO2007106617A3 (en) * 2006-01-30 2008-03-20 Talecris Biotherapeutics Inc Method of treatment and prophylaxis of diseases related to amyloid deposition using igm
CN102584934A (zh) * 2012-03-19 2012-07-18 江西博雅生物制药股份有限公司 一种静注人免疫球蛋白的制备工艺

Also Published As

Publication number Publication date
JPH0383932A (ja) 1991-04-09
EP0413187A1 (de) 1991-02-20
ES2070960T3 (es) 1995-06-16
JPH0768144B2 (ja) 1995-07-26
DE59008883D1 (de) 1995-05-18
ATE120963T1 (de) 1995-04-15
US5075425A (en) 1991-12-24
EP0413187B1 (de) 1995-04-12

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Legal Events

Date Code Title Description
8100 Publication of patent without earlier publication of application
D1 Grant (no unexamined application published) patent law 81
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee