DE3888536D1 - Polyanhydride mit verbesserten hydrolytischen degradierungseigenschaften. - Google Patents

Polyanhydride mit verbesserten hydrolytischen degradierungseigenschaften.

Info

Publication number
DE3888536D1
DE3888536D1 DE88906761T DE3888536T DE3888536D1 DE 3888536 D1 DE3888536 D1 DE 3888536D1 DE 88906761 T DE88906761 T DE 88906761T DE 3888536 T DE3888536 T DE 3888536T DE 3888536 D1 DE3888536 D1 DE 3888536D1
Authority
DE
Germany
Prior art keywords
polyanhydrides
improved hydrolytic
degrading properties
degrading
properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88906761T
Other languages
English (en)
Other versions
DE3888536T2 (de
Inventor
Abraham Domb
Robert Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of DE3888536D1 publication Critical patent/DE3888536D1/de
Application granted granted Critical
Publication of DE3888536T2 publication Critical patent/DE3888536T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G67/00Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
    • C08G67/04Polyanhydrides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE3888536T 1987-07-31 1988-07-28 Polyanhydride mit verbesserten hydrolytischen degradierungseigenschaften. Expired - Lifetime DE3888536T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/080,631 US4857311A (en) 1987-07-31 1987-07-31 Polyanhydrides with improved hydrolytic degradation properties
PCT/US1988/002569 WO1989000855A1 (en) 1987-07-31 1988-07-28 Polyanhydrides with improved hydrolytic degradation properties

Publications (2)

Publication Number Publication Date
DE3888536D1 true DE3888536D1 (de) 1994-04-21
DE3888536T2 DE3888536T2 (de) 1994-07-21

Family

ID=22158602

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3888536T Expired - Lifetime DE3888536T2 (de) 1987-07-31 1988-07-28 Polyanhydride mit verbesserten hydrolytischen degradierungseigenschaften.

Country Status (8)

Country Link
US (1) US4857311A (de)
EP (1) EP0368912B1 (de)
JP (1) JPH0757797B2 (de)
AU (1) AU2258088A (de)
CA (1) CA1335858C (de)
DE (1) DE3888536T2 (de)
NZ (1) NZ225323A (de)
WO (1) WO1989000855A1 (de)

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US5270419A (en) * 1990-01-19 1993-12-14 Nova Pharmaceutical Corporation Polyanhydrides of oligomerized unsaturated aliphatic acids
US5240963A (en) * 1990-01-19 1993-08-31 Nova Pharmaceutical Corporation Branched polyanhydrides
US5175235A (en) * 1990-06-04 1992-12-29 Nova Pharmaceutical Corporation Branched polyanhydrides
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Also Published As

Publication number Publication date
WO1989000855A1 (en) 1989-02-09
EP0368912A4 (en) 1990-12-19
NZ225323A (en) 1990-05-28
AU2258088A (en) 1989-03-01
CA1335858C (en) 1995-06-06
JPH02504158A (ja) 1990-11-29
JPH0757797B2 (ja) 1995-06-21
DE3888536T2 (de) 1994-07-21
EP0368912B1 (de) 1994-03-16
EP0368912A1 (de) 1990-05-23
US4857311A (en) 1989-08-15

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