DE3869258D1 - Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number
DE3869258D1
DE3869258D1 DE8888401890T DE3869258T DE3869258D1 DE 3869258 D1 DE3869258 D1 DE 3869258D1 DE 8888401890 T DE8888401890 T DE 8888401890T DE 3869258 T DE3869258 T DE 3869258T DE 3869258 D1 DE3869258 D1 DE 3869258D1
Authority
DE
Germany
Prior art keywords
amino
hydrogen
radical
production
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888401890T
Other languages
English (en)
Inventor
Jean-Claude Hardy
Christian Renault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of DE3869258D1 publication Critical patent/DE3869258D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Epoxy Resins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE8888401890T 1987-07-23 1988-07-21 Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. Expired - Fee Related DE3869258D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8710453A FR2618437B1 (fr) 1987-07-23 1987-07-23 Nouveaux derives du benzopyranne, leur preparation et les medicaments qui les contiennent

Publications (1)

Publication Number Publication Date
DE3869258D1 true DE3869258D1 (de) 1992-04-23

Family

ID=9353484

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888401890T Expired - Fee Related DE3869258D1 (de) 1987-07-23 1988-07-21 Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (16)

Country Link
US (1) US4977166A (de)
EP (1) EP0300908B1 (de)
JP (1) JPS6440476A (de)
KR (1) KR890002121A (de)
AT (1) ATE73791T1 (de)
AU (1) AU606184B2 (de)
DE (1) DE3869258D1 (de)
DK (1) DK411388A (de)
FI (1) FI883486A (de)
FR (1) FR2618437B1 (de)
GR (1) GR3004090T3 (de)
HU (1) HUT54145A (de)
NO (1) NO883279L (de)
NZ (1) NZ225520A (de)
PT (1) PT88083B (de)
ZA (1) ZA885374B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
AU626881B2 (en) * 1988-07-14 1992-08-13 F. Hoffmann-La Roche Ag Benzofused heterocyclics used as pharmaceuticals
FR2642069B1 (fr) * 1989-01-20 1991-04-12 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent
US5006523A (en) * 1989-10-26 1991-04-09 E. R. Squibb & Sons, Inc. Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
FR2658823B1 (fr) * 1990-02-27 1992-04-30 Adir Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent .
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
DE4321366A1 (de) * 1993-06-26 1995-01-05 Merck Patent Gmbh Piperidine und Piperazine
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
DK0737189T3 (da) * 1993-12-28 2000-03-06 Upjohn Co Heterocycliske forbindelser til behandling af CNS-forstyrrelser og cardiovaskulære forstyrrelser
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
FR2717479B1 (fr) * 1994-03-18 1996-06-07 Pf Medicament Nouvelles 3-(omega-benzoylpipéridino) alcoyl)-4H-Benzopyran-4-ones, leur préparation et leur application en thérapeutique.
FR2724656B1 (fr) * 1994-09-15 1996-12-13 Adir Nouveaux derives du benzopyranne, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2763335B1 (fr) * 1997-05-16 2000-11-24 Adir Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB9912410D0 (en) * 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
BRPI0613771B1 (pt) * 2005-07-22 2021-11-23 Mochida Pharmaceutical Co., Ltd Composto derivado de heterociclideno acetamida, composição farmacêutica e antagonista de receptor de tipo i vaniloide com potencial de receptor transitório (trpv1)
EP2299814A4 (de) * 2008-05-27 2011-06-15 Reviva Pharmaceuticals Inc Zusammensetzungen, synthese und verfahren zur verwendung von antipsychotika auf piperazinbasis
CA2753599C (en) 2009-02-26 2017-03-14 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of utilizing arylpiperazine derivatives
RU2477130C1 (ru) * 2011-07-12 2013-03-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" Средство, обладающее антиаритмическим, антифибрилляторным, противоишемическим действием, и фармацевтическая композиция на его основе

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1583811A (en) * 1977-05-09 1981-02-04 Laroche Navarron Sa Chromene derivatives
DE3300004A1 (de) * 1983-01-03 1984-07-12 Bayer Ag, 5090 Leverkusen Substituierte 4-aminomethylenchromane bzw. -chromene, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE3411993A1 (de) * 1984-03-31 1985-10-10 Bayer Ag, 5090 Leverkusen Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimittel
US4803203A (en) * 1986-11-05 1989-02-07 Warner-Lambert Company Phenyl and heterocyclic piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents

Also Published As

Publication number Publication date
PT88083B (pt) 1995-03-01
NO883279D0 (no) 1988-07-22
PT88083A (pt) 1989-06-30
ATE73791T1 (de) 1992-04-15
KR890002121A (ko) 1989-04-08
NZ225520A (en) 1991-03-26
US4977166A (en) 1990-12-11
FR2618437B1 (fr) 1989-11-17
DK411388A (da) 1989-01-24
EP0300908B1 (de) 1992-03-18
GR3004090T3 (de) 1993-03-31
AU1971388A (en) 1989-01-27
FI883486A (fi) 1989-01-24
AU606184B2 (en) 1991-01-31
DK411388D0 (da) 1988-07-22
ZA885374B (en) 1989-03-29
FI883486A0 (fi) 1988-07-22
EP0300908A1 (de) 1989-01-25
NO883279L (no) 1989-01-24
JPS6440476A (en) 1989-02-10
HUT54145A (en) 1991-01-28
FR2618437A1 (fr) 1989-01-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee