DE3869258D1 - Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents
Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.Info
- Publication number
- DE3869258D1 DE3869258D1 DE8888401890T DE3869258T DE3869258D1 DE 3869258 D1 DE3869258 D1 DE 3869258D1 DE 8888401890 T DE8888401890 T DE 8888401890T DE 3869258 T DE3869258 T DE 3869258T DE 3869258 D1 DE3869258 D1 DE 3869258D1
- Authority
- DE
- Germany
- Prior art keywords
- amino
- hydrogen
- radical
- production
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Epoxy Resins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8710453A FR2618437B1 (fr) | 1987-07-23 | 1987-07-23 | Nouveaux derives du benzopyranne, leur preparation et les medicaments qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3869258D1 true DE3869258D1 (de) | 1992-04-23 |
Family
ID=9353484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888401890T Expired - Fee Related DE3869258D1 (de) | 1987-07-23 | 1988-07-21 | Benzopyran-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4977166A (de) |
EP (1) | EP0300908B1 (de) |
JP (1) | JPS6440476A (de) |
KR (1) | KR890002121A (de) |
AT (1) | ATE73791T1 (de) |
AU (1) | AU606184B2 (de) |
DE (1) | DE3869258D1 (de) |
DK (1) | DK411388A (de) |
FI (1) | FI883486A (de) |
FR (1) | FR2618437B1 (de) |
GR (1) | GR3004090T3 (de) |
HU (1) | HUT54145A (de) |
NO (1) | NO883279L (de) |
NZ (1) | NZ225520A (de) |
PT (1) | PT88083B (de) |
ZA (1) | ZA885374B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4957928A (en) * | 1986-06-26 | 1990-09-18 | Ciba-Geigy Corporation | Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds |
AU626881B2 (en) * | 1988-07-14 | 1992-08-13 | F. Hoffmann-La Roche Ag | Benzofused heterocyclics used as pharmaceuticals |
FR2642069B1 (fr) * | 1989-01-20 | 1991-04-12 | Rhone Poulenc Sante | Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5006523A (en) * | 1989-10-26 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Antiarrhythmic agents: aryl cyanoguanidine potassium channel blockers |
US5032598A (en) * | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents |
US5112824A (en) * | 1989-12-08 | 1992-05-12 | Merck & Co., Inc. | Benzofuran compounds as class III antiarrhythmic agents |
US5215989A (en) * | 1989-12-08 | 1993-06-01 | Merck & Co., Inc. | Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents |
US5032604A (en) * | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Class III antiarrhythmic agents |
FR2658823B1 (fr) * | 1990-02-27 | 1992-04-30 | Adir | Nouveaux derives d'aminomethylpiperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent . |
DE4319038A1 (de) * | 1993-06-08 | 1994-12-15 | Bayer Ag | Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung |
DE4321366A1 (de) * | 1993-06-26 | 1995-01-05 | Merck Patent Gmbh | Piperidine und Piperazine |
US5382587A (en) * | 1993-06-30 | 1995-01-17 | Merck & Co., Inc. | Spirocycles |
US5403846A (en) * | 1993-11-22 | 1995-04-04 | Merck & Co., Inc. | Spirocycles |
DK0737189T3 (da) * | 1993-12-28 | 2000-03-06 | Upjohn Co | Heterocycliske forbindelser til behandling af CNS-forstyrrelser og cardiovaskulære forstyrrelser |
US5439914A (en) * | 1994-02-18 | 1995-08-08 | Merck & Co., Inc. | Spirocycles |
FR2717479B1 (fr) * | 1994-03-18 | 1996-06-07 | Pf Medicament | Nouvelles 3-(omega-benzoylpipéridino) alcoyl)-4H-Benzopyran-4-ones, leur préparation et leur application en thérapeutique. |
FR2724656B1 (fr) * | 1994-09-15 | 1996-12-13 | Adir | Nouveaux derives du benzopyranne, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
GB9912410D0 (en) * | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
BRPI0613771B1 (pt) * | 2005-07-22 | 2021-11-23 | Mochida Pharmaceutical Co., Ltd | Composto derivado de heterociclideno acetamida, composição farmacêutica e antagonista de receptor de tipo i vaniloide com potencial de receptor transitório (trpv1) |
EP2299814A4 (de) * | 2008-05-27 | 2011-06-15 | Reviva Pharmaceuticals Inc | Zusammensetzungen, synthese und verfahren zur verwendung von antipsychotika auf piperazinbasis |
CA2753599C (en) | 2009-02-26 | 2017-03-14 | Reviva Pharmaceuticals, Inc. | Compositions, synthesis, and methods of utilizing arylpiperazine derivatives |
RU2477130C1 (ru) * | 2011-07-12 | 2013-03-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" | Средство, обладающее антиаритмическим, антифибрилляторным, противоишемическим действием, и фармацевтическая композиция на его основе |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1583811A (en) * | 1977-05-09 | 1981-02-04 | Laroche Navarron Sa | Chromene derivatives |
DE3300004A1 (de) * | 1983-01-03 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Substituierte 4-aminomethylenchromane bzw. -chromene, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
DE3411993A1 (de) * | 1984-03-31 | 1985-10-10 | Bayer Ag, 5090 Leverkusen | Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimittel |
US4803203A (en) * | 1986-11-05 | 1989-02-07 | Warner-Lambert Company | Phenyl and heterocyclic piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents |
-
1987
- 1987-07-23 FR FR8710453A patent/FR2618437B1/fr not_active Expired
-
1988
- 1988-07-21 DE DE8888401890T patent/DE3869258D1/de not_active Expired - Fee Related
- 1988-07-21 AT AT88401890T patent/ATE73791T1/de active
- 1988-07-21 JP JP63182768A patent/JPS6440476A/ja active Pending
- 1988-07-21 KR KR1019880009213A patent/KR890002121A/ko not_active Application Discontinuation
- 1988-07-21 EP EP88401890A patent/EP0300908B1/de not_active Expired - Lifetime
- 1988-07-22 ZA ZA885374A patent/ZA885374B/xx unknown
- 1988-07-22 NO NO88883279A patent/NO883279L/no unknown
- 1988-07-22 NZ NZ225520A patent/NZ225520A/en unknown
- 1988-07-22 AU AU19713/88A patent/AU606184B2/en not_active Ceased
- 1988-07-22 HU HU883880A patent/HUT54145A/hu unknown
- 1988-07-22 PT PT88083A patent/PT88083B/pt not_active IP Right Cessation
- 1988-07-22 FI FI883486A patent/FI883486A/fi not_active Application Discontinuation
- 1988-07-22 DK DK411388A patent/DK411388A/da not_active Application Discontinuation
-
1989
- 1989-03-22 US US07/327,093 patent/US4977166A/en not_active Expired - Fee Related
-
1992
- 1992-03-19 GR GR910401355T patent/GR3004090T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT88083B (pt) | 1995-03-01 |
NO883279D0 (no) | 1988-07-22 |
PT88083A (pt) | 1989-06-30 |
ATE73791T1 (de) | 1992-04-15 |
KR890002121A (ko) | 1989-04-08 |
NZ225520A (en) | 1991-03-26 |
US4977166A (en) | 1990-12-11 |
FR2618437B1 (fr) | 1989-11-17 |
DK411388A (da) | 1989-01-24 |
EP0300908B1 (de) | 1992-03-18 |
GR3004090T3 (de) | 1993-03-31 |
AU1971388A (en) | 1989-01-27 |
FI883486A (fi) | 1989-01-24 |
AU606184B2 (en) | 1991-01-31 |
DK411388D0 (da) | 1988-07-22 |
ZA885374B (en) | 1989-03-29 |
FI883486A0 (fi) | 1988-07-22 |
EP0300908A1 (de) | 1989-01-25 |
NO883279L (no) | 1989-01-24 |
JPS6440476A (en) | 1989-02-10 |
HUT54145A (en) | 1991-01-28 |
FR2618437A1 (fr) | 1989-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |