DE3854288T2 - Cephalosporinderivate und Verfahren zur Herstellung von Cephem-Verbindungen. - Google Patents

Cephalosporinderivate und Verfahren zur Herstellung von Cephem-Verbindungen.

Info

Publication number
DE3854288T2
DE3854288T2 DE3854288T DE3854288T DE3854288T2 DE 3854288 T2 DE3854288 T2 DE 3854288T2 DE 3854288 T DE3854288 T DE 3854288T DE 3854288 T DE3854288 T DE 3854288T DE 3854288 T2 DE3854288 T2 DE 3854288T2
Authority
DE
Germany
Prior art keywords
preparation
cephalosporin derivatives
cephem compounds
compounds
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3854288T
Other languages
English (en)
Other versions
DE3854288D1 (de
Inventor
Hendrik Adrianus Witkamp
Jan Verweij
Koning Jan Jacobus De
Herman Hendrik Grootveld
Everardus Johannes A Leenderts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Application granted granted Critical
Publication of DE3854288D1 publication Critical patent/DE3854288D1/de
Publication of DE3854288T2 publication Critical patent/DE3854288T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Control Of Transmission Device (AREA)
  • Rigid Containers With Two Or More Constituent Elements (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
DE3854288T 1987-07-10 1988-07-08 Cephalosporinderivate und Verfahren zur Herstellung von Cephem-Verbindungen. Expired - Fee Related DE3854288T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87201316 1987-07-10

Publications (2)

Publication Number Publication Date
DE3854288D1 DE3854288D1 (de) 1995-09-14
DE3854288T2 true DE3854288T2 (de) 1996-01-11

Family

ID=8197637

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3854288T Expired - Fee Related DE3854288T2 (de) 1987-07-10 1988-07-08 Cephalosporinderivate und Verfahren zur Herstellung von Cephem-Verbindungen.

Country Status (14)

Country Link
US (3) US4921954A (de)
JP (1) JPH0193591A (de)
KR (1) KR890002175A (de)
CN (1) CN1030760A (de)
AT (1) ATE126230T1 (de)
AU (1) AU615920B2 (de)
DE (1) DE3854288T2 (de)
DK (1) DK381488A (de)
FI (1) FI883267A (de)
HU (1) HU208541B (de)
IL (1) IL86941A (de)
NO (1) NO883080L (de)
NZ (1) NZ225286A (de)
PT (1) PT87945B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86941A (en) * 1987-07-10 1993-07-08 Gist Brocades Nv Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US6383773B2 (en) 1998-04-23 2002-05-07 Massachusetts Institute Of Technology Penicillin conversion
CA2472690A1 (en) * 2002-01-07 2003-07-17 Abbott Gmbh & Co. Kg Crystallization of amino acids using ultrasonic agitation
EP1554288A1 (de) * 2002-10-08 2005-07-20 Ranbaxy Laboratories, Ltd. Verfahren zur herstellung von (z)-isomer angereichertem 7-amino-3-propen-1-yl-3-cephem-4-carbonsäure
CN101759709B (zh) * 2008-12-26 2012-07-04 上海新先锋药业有限公司 7-ACP·HCl的精制工艺
WO2016028670A1 (en) * 2014-08-18 2016-02-25 Merck Sharp & Dohme Corp. Salt forms of ceftolozane
AU2015308350B2 (en) 2014-08-29 2020-03-05 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
WO2016109259A2 (en) 2014-12-30 2016-07-07 Merck Sharp & Dohme Corp. Synthesis of cephalosporin compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032521A (en) * 1972-12-29 1977-06-28 Merck & Co., Inc. Cephalosporin phosphonic acid, sulfonic acid and sulfonamide compounds
JPS5826355B2 (ja) * 1974-07-24 1983-06-02 ザイダンホウジン サンギヨウカガクケンキユウキヨウカイ ７− アミノセフアロスポランサンユウドウタイノ セイゾウホウホウ
DE2927462A1 (de) * 1979-07-06 1981-01-29 Bayer Ag Cephalosporin-1,1-dioxide, ihre herstellung und ihre verwendung
AU566944B2 (en) * 1983-10-07 1987-11-05 Gist-Brocades N.V. Preparation of 3-cephem derivatives
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
JPS62212391A (ja) * 1986-03-11 1987-09-18 Shionogi & Co Ltd セフエムアルコキシ基の脱離法
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
IL86941A (en) * 1987-07-10 1993-07-08 Gist Brocades Nv Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process

Also Published As

Publication number Publication date
NZ225286A (en) 1990-08-28
HUT47941A (en) 1989-04-28
AU1866388A (en) 1989-01-12
DK381488A (da) 1989-01-11
PT87945B (pt) 1995-03-01
FI883267A (fi) 1989-01-11
FI883267A0 (fi) 1988-07-08
DE3854288D1 (de) 1995-09-14
AU615920B2 (en) 1991-10-17
DK381488D0 (da) 1988-07-08
NO883080D0 (no) 1988-07-08
IL86941A0 (en) 1988-12-30
US5164494A (en) 1992-11-17
US5359058A (en) 1994-10-25
US4921954A (en) 1990-05-01
ATE126230T1 (de) 1995-08-15
CN1030760A (zh) 1989-02-01
KR890002175A (ko) 1989-04-08
PT87945A (pt) 1989-06-30
IL86941A (en) 1993-07-08
JPH0193591A (ja) 1989-04-12
HU208541B (en) 1993-11-29
NO883080L (no) 1989-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee