ATE126230T1 - Cephalosporinderivate und verfahren zur herstellung von cephem-verbindungen. - Google Patents

Cephalosporinderivate und verfahren zur herstellung von cephem-verbindungen.

Info

Publication number
ATE126230T1
ATE126230T1 AT88201437T AT88201437T ATE126230T1 AT E126230 T1 ATE126230 T1 AT E126230T1 AT 88201437 T AT88201437 T AT 88201437T AT 88201437 T AT88201437 T AT 88201437T AT E126230 T1 ATE126230 T1 AT E126230T1
Authority
AT
Austria
Prior art keywords
cephem compounds
cephalosporine derivatives
producing
producing cephem
compounds
Prior art date
Application number
AT88201437T
Other languages
English (en)
Inventor
Hendrik Adrianus Witkamp
Jan Verweij
Koning Jan Jacobus De
Herman Hendrik Grootveld
Everardus Johannes A Leenderts
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Application granted granted Critical
Publication of ATE126230T1 publication Critical patent/ATE126230T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Control Of Transmission Device (AREA)
  • Rigid Containers With Two Or More Constituent Elements (AREA)
AT88201437T 1987-07-10 1988-07-08 Cephalosporinderivate und verfahren zur herstellung von cephem-verbindungen. ATE126230T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87201316 1987-07-10

Publications (1)

Publication Number Publication Date
ATE126230T1 true ATE126230T1 (de) 1995-08-15

Family

ID=8197637

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88201437T ATE126230T1 (de) 1987-07-10 1988-07-08 Cephalosporinderivate und verfahren zur herstellung von cephem-verbindungen.

Country Status (14)

Country Link
US (3) US4921954A (de)
JP (1) JPH0193591A (de)
KR (1) KR890002175A (de)
CN (1) CN1030760A (de)
AT (1) ATE126230T1 (de)
AU (1) AU615920B2 (de)
DE (1) DE3854288T2 (de)
DK (1) DK381488A (de)
FI (1) FI883267A (de)
HU (1) HU208541B (de)
IL (1) IL86941A (de)
NO (1) NO883080L (de)
NZ (1) NZ225286A (de)
PT (1) PT87945B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86941A (en) * 1987-07-10 1993-07-08 Gist Brocades Nv Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US6383773B2 (en) 1998-04-23 2002-05-07 Massachusetts Institute Of Technology Penicillin conversion
MXPA04006631A (es) * 2002-01-07 2004-11-10 Abbott Gmbh & Co Kg Cristalizacion de aminoacidos utilizando agitacion ultrasonica.
US20060173176A1 (en) * 2002-10-08 2006-08-03 Yatendra Kumar Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4-carboxylic acid
CN101759709B (zh) * 2008-12-26 2012-07-04 上海新先锋药业有限公司 7-ACP·HCl的精制工艺
WO2016028670A1 (en) * 2014-08-18 2016-02-25 Merck Sharp & Dohme Corp. Salt forms of ceftolozane
AU2015308350B2 (en) 2014-08-29 2020-03-05 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
US10214543B2 (en) 2014-12-30 2019-02-26 Merck Sharp & Dohme Corp. Synthesis of cephalosporin compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032521A (en) * 1972-12-29 1977-06-28 Merck & Co., Inc. Cephalosporin phosphonic acid, sulfonic acid and sulfonamide compounds
JPS5826355B2 (ja) * 1974-07-24 1983-06-02 ザイダンホウジン サンギヨウカガクケンキユウキヨウカイ ７− アミノセフアロスポランサンユウドウタイノ セイゾウホウホウ
DE2927462A1 (de) * 1979-07-06 1981-01-29 Bayer Ag Cephalosporin-1,1-dioxide, ihre herstellung und ihre verwendung
AU566944B2 (en) * 1983-10-07 1987-11-05 Gist-Brocades N.V. Preparation of 3-cephem derivatives
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
JPS62212391A (ja) * 1986-03-11 1987-09-18 Shionogi & Co Ltd セフエムアルコキシ基の脱離法
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
IL86941A (en) * 1987-07-10 1993-07-08 Gist Brocades Nv Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process

Also Published As

Publication number Publication date
US5359058A (en) 1994-10-25
AU1866388A (en) 1989-01-12
KR890002175A (ko) 1989-04-08
NO883080L (no) 1989-01-11
AU615920B2 (en) 1991-10-17
DK381488A (da) 1989-01-11
JPH0193591A (ja) 1989-04-12
CN1030760A (zh) 1989-02-01
NO883080D0 (no) 1988-07-08
DE3854288T2 (de) 1996-01-11
US4921954A (en) 1990-05-01
PT87945B (pt) 1995-03-01
US5164494A (en) 1992-11-17
HUT47941A (en) 1989-04-28
DK381488D0 (da) 1988-07-08
FI883267A (fi) 1989-01-11
FI883267A0 (fi) 1988-07-08
PT87945A (pt) 1989-06-30
HU208541B (en) 1993-11-29
IL86941A (en) 1993-07-08
DE3854288D1 (de) 1995-09-14
IL86941A0 (en) 1988-12-30
NZ225286A (en) 1990-08-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee