DE3850818T2 - Fluor enthaltende Renin-Inhibitoren. - Google Patents

Fluor enthaltende Renin-Inhibitoren.

Info

Publication number
DE3850818T2
DE3850818T2 DE3850818T DE3850818T DE3850818T2 DE 3850818 T2 DE3850818 T2 DE 3850818T2 DE 3850818 T DE3850818 T DE 3850818T DE 3850818 T DE3850818 T DE 3850818T DE 3850818 T2 DE3850818 T2 DE 3850818T2
Authority
DE
Germany
Prior art keywords
renin inhibitors
fluorine
chem
containing renin
cf2conhch3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3850818T
Other languages
English (en)
Other versions
DE3850818D1 (de
Inventor
Dennis Jay Hoover
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3850818D1 publication Critical patent/DE3850818D1/de
Publication of DE3850818T2 publication Critical patent/DE3850818T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE3850818T 1987-07-01 1988-06-24 Fluor enthaltende Renin-Inhibitoren. Expired - Fee Related DE3850818T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6898987A 1987-07-01 1987-07-01

Publications (2)

Publication Number Publication Date
DE3850818D1 DE3850818D1 (de) 1994-09-01
DE3850818T2 true DE3850818T2 (de) 1994-11-17

Family

ID=22085994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3850818T Expired - Fee Related DE3850818T2 (de) 1987-07-01 1988-06-24 Fluor enthaltende Renin-Inhibitoren.

Country Status (9)

Country Link
EP (1) EP0297815B1 (de)
JP (1) JPH0757759B2 (de)
AT (1) ATE109157T1 (de)
CA (1) CA1322075C (de)
DE (1) DE3850818T2 (de)
DK (1) DK362688A (de)
ES (1) ES2056930T3 (de)
FI (1) FI883134A (de)
PT (1) PT87867B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8619182D0 (en) * 1986-08-06 1986-09-17 Sandoz Ltd Peptides & derivatives
EP0369391A3 (de) * 1988-11-15 1991-09-25 Boehringer Ingelheim Pharmaceuticals Inc. N-substituierte Amide
DE4126485A1 (de) * 1991-08-10 1993-02-11 Bayer Ag Trifluormethyl-haltige pseudopeptide
JP2005259307A (ja) * 2004-03-15 2005-09-22 Sony Corp 光ピックアップ及びディスクドライブ装置
JP5623693B2 (ja) * 2005-11-24 2014-11-12 旭化成ケミカルズ株式会社 メタクリル樹脂及びその製造方法
CN102482360A (zh) 2009-10-22 2012-05-30 旭化成化学株式会社 甲基丙烯酸类树脂、其成形体及甲基丙烯酸类树脂的制造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006379A1 (en) * 1985-04-19 1986-11-06 The Upjohn Company Dihalo-statine substituted renin inhibitors
DE3538749A1 (de) * 1985-10-31 1987-05-07 Merck Patent Gmbh Peptide

Also Published As

Publication number Publication date
ATE109157T1 (de) 1994-08-15
PT87867B (pt) 1995-05-04
JPH0757759B2 (ja) 1995-06-21
FI883134A0 (fi) 1988-06-30
DK362688D0 (da) 1988-06-30
EP0297815B1 (de) 1994-07-27
ES2056930T3 (es) 1994-10-16
CA1322075C (en) 1993-09-07
EP0297815A2 (de) 1989-01-04
JPS6422865A (en) 1989-01-25
PT87867A (pt) 1989-06-30
FI883134A (fi) 1989-01-02
EP0297815A3 (en) 1990-06-06
DK362688A (da) 1989-02-14
DE3850818D1 (de) 1994-09-01

Similar Documents

Publication Publication Date Title
NO2006018I1 (no) Entekavir:(2-amino-1,9-dihydro-9Ä(1S,3R,4S)-4hydroksy-3-(hydroksymetyl)-2-metylencyklopentylÜ-6H-purin-6-on og hydrater derav, saerlig monohydrat
HU9401020D0 (en) Cyclic ureas and analogues
ES2101960T3 (es) Lactamas benzo-condensadas.
FI904327A0 (fi) N-substituerad-4-pyrimidinaminer och -pyrimidindiaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
DE69010375T2 (de) Protease-Hemmer.
NO175256C (no) Analogifremgangsmåte til fremstilling av terapeutisk aktive 4-oksokinolin-3-karboksylsyrederivater
NO933376D0 (no) Morfinan-derivater og medisinsk anvendelse derav
ATE88891T1 (de) Verfahren zur verbesserung des gedaechnisses oder zur beseitigung des gedaechnis-mangels mit arylamido-(und arylthioamido)-azabicycloalkanen.
NO174549C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser
NO173867C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzamider
NO902555D0 (no) N-heteroaryl-purin-6-aminer og fremgangsmaate for fremstilling derav.
DE3850818D1 (de) Fluor enthaltende Renin-Inhibitoren.
ES2034324T3 (es) Procedimiento de sintesis industrial de alfa amino diacidos n alquilados o de esteres de ellos.
EP0882721A4 (de) 4-substituierte 2,7-dideoxy-7-fluoro-2,3-didehydro-sialsäuren
DK361587D0 (da) Thiazolyleddikesyrederivater og fremgangsmaader til fremstilling deraf
SE7709913L (sv) Sett att framstella penta peptider
ATE204880T1 (de) N-acyldipeptide, und pharmazeutische präparate davon
EA200001107A1 (ru) ПРОИЗВОДНЫЕ ОКТАГИДРО-6,10-ДИОКСО-6H-ПИРИДАЗИНО [1,2-a] [1,2] ДИАЗЕПИН-1-КАРБОНОВОЙ КИСЛОТЫ, СПОСОБ ПОЛУЧЕНИЯ И ИХ ПРИМЕНЕНИЕ ДЛЯ ПОЛУЧЕНИЯ ТЕРАПЕВТИЧЕСКИ АКТИВНЫХ СОЕДИНЕНИЙ
NO903927L (no) N-azabicyklo(3.3.0)oktan-amider av aromatiske syrer.
GB2006196A (en) Phenylacetamides with analgesic activity
DE69405999T2 (de) Pharmazeutisch wirksame enantiomere
GB2013689A (en) Enkephalin analogues
SE7809127L (sv) Allenaminer
KR900000363A (ko) 1-카바(데티아)세팔로스포린용 중간생성물
ATE36536T1 (de) Phosphoroimidate.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee