DE3789781T2 - Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper. - Google Patents

Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper.

Info

Publication number
DE3789781T2
DE3789781T2 DE3789781T DE3789781T DE3789781T2 DE 3789781 T2 DE3789781 T2 DE 3789781T2 DE 3789781 T DE3789781 T DE 3789781T DE 3789781 T DE3789781 T DE 3789781T DE 3789781 T2 DE3789781 T2 DE 3789781T2
Authority
DE
Germany
Prior art keywords
antibodies
methods
antigens
production
cell lines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3789781T
Other languages
English (en)
Other versions
DE3789781D1 (de
Inventor
Garth L Nicolson
Susan M North
Peter A Steck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of DE3789781D1 publication Critical patent/DE3789781D1/de
Application granted granted Critical
Publication of DE3789781T2 publication Critical patent/DE3789781T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y10S436/813—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Stereophonic System (AREA)
  • Communication Control (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Prostheses (AREA)
  • Air Conditioning Control Device (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE3789781T 1986-04-01 1987-04-01 Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper. Expired - Fee Related DE3789781T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/846,938 US5030559A (en) 1986-04-01 1986-04-01 Methods and compositions for the identification of metastatic human tumors

Publications (2)

Publication Number Publication Date
DE3789781D1 DE3789781D1 (de) 1994-06-16
DE3789781T2 true DE3789781T2 (de) 1994-11-10

Family

ID=25299361

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789781T Expired - Fee Related DE3789781T2 (de) 1986-04-01 1987-04-01 Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper.

Country Status (11)

Country Link
US (1) US5030559A (de)
EP (1) EP0240341B1 (de)
JP (1) JPH0742320B2 (de)
AT (1) ATE105569T1 (de)
AU (1) AU599364B2 (de)
CA (1) CA1307478C (de)
DE (1) DE3789781T2 (de)
DK (1) DK162387A (de)
ES (1) ES2051737T3 (de)
FI (1) FI89806C (de)
NO (1) NO175642C (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE403802B (sv) * 1972-10-10 1978-09-04 Buchegger Masch Reinigung Anordning for rengoring och avfettning av maskindelar och liknande
US5646004A (en) * 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
US5663051A (en) * 1994-08-31 1997-09-02 Activated Cell Therapy, Inc. Separation apparatus and method
US5840502A (en) * 1994-08-31 1998-11-24 Activated Cell Therapy, Inc. Methods for enriching specific cell-types by density gradient centrifugation
US5648223A (en) * 1994-08-31 1997-07-15 Activated Cell Therapy, Inc. Methods for enriching breast tumor cells
DE19530272C1 (de) * 1995-08-17 1996-11-21 Univ Eberhard Karls Antikörper 103 B2
DE19530273C1 (de) * 1995-08-17 1996-12-12 Univ Eberhard Karls Antikörper 105A5
US6821731B2 (en) * 2000-11-28 2004-11-23 Wyeth Expression analysis of FKBP nucleic acids and polypeptides useful in the diagnosis of prostate cancer
MXPA03004579A (es) * 2000-11-28 2003-09-04 Wyeth Corp Analisis de expresion de acidos nucleicos del regulador de cromatina dependiente de actina y polipeptidos utiles en diagnostico y tratamiento del cancer de prostata.
EP1343912A2 (de) * 2000-11-28 2003-09-17 Wyeth Expressionsanalyse von kiaa nukleinsäuren und polypeptiden, geeignet zur diagnose und zur behandlung von prostatakrebs
US7169722B2 (en) * 2002-01-28 2007-01-30 Guardian Industries Corp. Clear glass composition with high visible transmittance
US7482116B2 (en) 2002-06-07 2009-01-27 Dna Genotek Inc. Compositions and methods for obtaining nucleic acids from sputum
WO2008031020A2 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
US20090324596A1 (en) 2008-06-30 2009-12-31 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
US10745701B2 (en) 2007-06-28 2020-08-18 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
RU2014101490A (ru) * 2011-06-19 2015-07-27 Эйбоджен, Инк. Устройства, растворы и способы для сбора образцов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697638A (en) * 1970-06-01 1972-10-10 Hoffmann La Roche Antigens
US4145336A (en) * 1976-04-30 1979-03-20 Scripps Clinic And Research Foundation Carcinoembryonic antigen isomer
US4140753A (en) * 1976-04-30 1979-02-20 Scripps Clinic & Research Foundation Diagnostic method and reagent
IN150740B (de) * 1978-11-24 1982-12-04 Hoffmann La Roche
US4444744A (en) * 1980-03-03 1984-04-24 Goldenberg Milton David Tumor localization and therapy with labeled antibodies to cell surface antigens
EP0160446B1 (de) * 1984-05-01 1992-06-17 Ciba Corning Diagnostics Corp. Brusttumorassoziiertes Antigen und monoklonale Antikörper dazu

Also Published As

Publication number Publication date
ATE105569T1 (de) 1994-05-15
US5030559A (en) 1991-07-09
DE3789781D1 (de) 1994-06-16
DK162387D0 (da) 1987-03-31
NO175642B (de) 1994-08-01
FI871411A (fi) 1987-10-02
DK162387A (da) 1987-10-02
CA1307478C (en) 1992-09-15
FI89806C (fi) 1993-11-25
ES2051737T3 (es) 1994-07-01
JPH0742320B2 (ja) 1995-05-10
NO871352L (no) 1987-10-02
JPS62253395A (ja) 1987-11-05
FI871411A0 (fi) 1987-03-31
AU7075387A (en) 1987-10-08
EP0240341B1 (de) 1994-05-11
NO871352D0 (no) 1987-03-31
EP0240341A2 (de) 1987-10-07
FI89806B (fi) 1993-08-13
EP0240341A3 (en) 1989-07-19
NO175642C (no) 1994-11-09
AU599364B2 (en) 1990-07-19

Similar Documents

Publication Publication Date Title
DE3789781T2 (de) Antigene, Antikörper und Verfahren zur Identifizierung humaner metastatischer Tumoren und Zellinien zur Herstellung dieser Antikörper.
FI92258B (fi) Onkostatiini-A:n käyttö diagnostisessa menetelmässä
EP0288082A3 (de) Tumor-spezifische Bestimmung von CA125-Ovarial-Krebsantigen
ATA328286A (de) Zell-linien und verfahren zur herstellung von humanen monoklonalen antikörpern sowie kit und verfahren zur bestimmung der anwesenheit von p.aeruginosa
DK21985A (da) Monoklonale antistoffer mod ikke-smaacellet lungecancer
JPS5386016A (en) Identification * diagnostic and immunological method for surface protein of cancer cell
GB2182949A (en) Monoclonal antibodies and antigens for human non-small cell lung carcinomas
IE802533L (en) Cancer cell antigens
DK0454782T3 (da) Cancer-beslægtet haptaglobin (Hpr.)
CA2294514A1 (en) Method for identification of cellular protein antigens and presence of antibodies to specific cellular protein antigens in serum
ES8707863A1 (es) Un procedimiento para producir un anticuerpo monoclonal para carcinoma de pulmon humano de celulas no pequenas.
DE3582191D1 (de) Verwendung eines spezifischen karzinomassoziierenden antigens (hapten), fucosylsialosylgangliotetrose (fuc-gm1) in diagnostischen und therapeutischen verfahren betreffend den menschlichen lungenkrebs (carcinomas von kleinen zellen).
NZ333075A (en) isolated protein markers for use in diagnosing esophageal cancer
AU538833B2 (en) Method of diagnosing arterosclerosis
EP0242154A3 (en) A novel tumor-associated antigen
IL67944A0 (en) Antibodies and antigens useful in the diagnosis and treatment of cancer,methods for the production thereof and methods for testing for the presence of cancer cells using the same
NO914094L (no) Nytt monoklonalt antistoff mot nytt antigen forbundet medhumantumorer

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee