DE3788463D1 - 3-Beta-(3,4-disubstituiertes succinimido)azetidinone. - Google Patents

3-Beta-(3,4-disubstituiertes succinimido)azetidinone.

Info

Publication number
DE3788463D1
DE3788463D1 DE87306089T DE3788463T DE3788463D1 DE 3788463 D1 DE3788463 D1 DE 3788463D1 DE 87306089 T DE87306089 T DE 87306089T DE 3788463 T DE3788463 T DE 3788463T DE 3788463 D1 DE3788463 D1 DE 3788463D1
Authority
DE
Germany
Prior art keywords
disubstituted
beta
succinimido
azetidinone
azetidinones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87306089T
Other languages
English (en)
Other versions
DE3788463T2 (de
Inventor
Robin David Grey Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE3788463D1 publication Critical patent/DE3788463D1/de
Application granted granted Critical
Publication of DE3788463T2 publication Critical patent/DE3788463T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
DE87306089T 1986-07-10 1987-07-09 3-Beta-(3,4-disubstituiertes succinimido)azetidinone. Expired - Fee Related DE3788463T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/884,124 US4734498A (en) 1986-07-10 1986-07-10 3β-succinimidoazetidinones as chiral intermediates

Publications (2)

Publication Number Publication Date
DE3788463D1 true DE3788463D1 (de) 1994-01-27
DE3788463T2 DE3788463T2 (de) 1994-04-28

Family

ID=25384007

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87306089T Expired - Fee Related DE3788463T2 (de) 1986-07-10 1987-07-09 3-Beta-(3,4-disubstituiertes succinimido)azetidinone.

Country Status (11)

Country Link
US (1) US4734498A (de)
EP (1) EP0252744B1 (de)
JP (1) JP2510600B2 (de)
KR (1) KR950013767B1 (de)
AT (1) ATE98644T1 (de)
CA (1) CA1320209C (de)
DE (1) DE3788463T2 (de)
ES (1) ES2061503T3 (de)
HU (1) HU197896B (de)
IE (1) IE61494B1 (de)
IL (1) IL83121A (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0715235Y2 (ja) * 1989-01-31 1995-04-10 鐘淵化学工業株式会社 画像読み取り装置に於けるセンサ素子の位置決め装置
US5225553A (en) * 1990-09-13 1993-07-06 Eli Lilly And Company Intermediates to 1-carbacephalosporins and process for preparation thereof
DE69131826T2 (de) * 1990-09-13 2000-05-25 Eli Lilly And Co., Indianapolis Zwischenprodukte für 1-Carbacephalosporin und Verfahren zur Herstellung dieser
US5159073A (en) * 1990-09-13 1992-10-27 Eli Lilly And Company Intermediates to 1-carbacephalosporins and process for preparation thereof
US5175256A (en) * 1990-09-28 1992-12-29 Neorx Corporation Protein labeling reagents
US5599336A (en) * 1992-07-02 1997-02-04 The Procter & Gamble Company Absorbent hydrogel fines in absorbent structures
EP0939632B1 (de) 1996-02-23 2005-10-05 Eli Lilly And Company Non-peptidische vasopressin via antagonisten
JP2000247934A (ja) * 1999-02-23 2000-09-12 Toray Ind Inc 高光学純度アミノ酸ベンジルエステルの製造法
US6706916B1 (en) 1999-02-23 2004-03-16 Toray Fine Chemicals Co., Ltd. Optically active amino acid derivatives and processes for the preparation of the same
JP4524841B2 (ja) * 1999-03-02 2010-08-18 東レ・ファインケミカル株式会社 光学活性アミノ酸エステル酒石酸アミドおよびその製造法
ES2666188T3 (es) * 2001-10-12 2018-05-03 Azevan Pharmaceuticals, Inc. Antagonistas del v1a de vasopresina beta-lactámicos
EP1868434A4 (de) 2005-03-22 2011-10-26 Azevan Pharmaceuticals Inc Beta-lactamylalkansäuren zur behandlung von prämenstruellen störungen
KR101523776B1 (ko) 2005-07-19 2015-05-28 아제반 파마슈티칼스, 인코퍼레이티드 베타-락타민 페닐알라닌, 시스테인 그리고 세린 바소프레신길항물질
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
KR100932221B1 (ko) * 2007-11-07 2009-12-16 강원대학교산학협력단 베타락탐 올리고머 및 이의 제조방법
PL2587919T3 (pl) 2010-07-01 2018-05-30 Azevan Pharmaceuticals, Inc. Sposoby leczenia zespołu stresu pourazowego
NZ724718A (en) 2014-03-28 2023-04-28 Azevan Pharmaceuticals Inc Compositions and methods for treating neurodegenerative diseases
CA3075759A1 (en) 2017-09-15 2019-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics

Also Published As

Publication number Publication date
HUT44536A (en) 1988-03-28
IL83121A (en) 1992-09-06
HU197896B (en) 1989-06-28
IE871841L (en) 1988-01-10
KR950013767B1 (ko) 1995-11-15
ATE98644T1 (de) 1994-01-15
CA1320209C (en) 1993-07-13
JP2510600B2 (ja) 1996-06-26
EP0252744B1 (de) 1993-12-15
ES2061503T3 (es) 1994-12-16
EP0252744A2 (de) 1988-01-13
US4734498A (en) 1988-03-29
EP0252744A3 (en) 1989-12-13
JPS6323858A (ja) 1988-02-01
IE61494B1 (en) 1994-11-02
KR880001638A (ko) 1988-04-25
DE3788463T2 (de) 1994-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee