DE3787333T2 - Zwischenprodukte für Antibiotika. - Google Patents

Zwischenprodukte für Antibiotika.

Info

Publication number
DE3787333T2
DE3787333T2 DE87306539T DE3787333T DE3787333T2 DE 3787333 T2 DE3787333 T2 DE 3787333T2 DE 87306539 T DE87306539 T DE 87306539T DE 3787333 T DE3787333 T DE 3787333T DE 3787333 T2 DE3787333 T2 DE 3787333T2
Authority
DE
Germany
Prior art keywords
antibiotics
azetidinones
intermediates
chlorides
aldimines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87306539T
Other languages
English (en)
Other versions
DE3787333D1 (de
Inventor
Robin David Grey Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3787333D1 publication Critical patent/DE3787333D1/de
Publication of DE3787333T2 publication Critical patent/DE3787333T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE87306539T 1986-07-24 1987-07-23 Zwischenprodukte für Antibiotika. Expired - Fee Related DE3787333T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/888,895 US4772694A (en) 1986-07-24 1986-07-24 Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates

Publications (2)

Publication Number Publication Date
DE3787333D1 DE3787333D1 (de) 1993-10-14
DE3787333T2 true DE3787333T2 (de) 1994-02-03

Family

ID=25394125

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87306539T Expired - Fee Related DE3787333T2 (de) 1986-07-24 1987-07-23 Zwischenprodukte für Antibiotika.

Country Status (10)

Country Link
US (1) US4772694A (de)
EP (1) EP0254578B1 (de)
JP (1) JPH0757752B2 (de)
KR (1) KR960000048B1 (de)
AT (1) ATE94165T1 (de)
CA (1) CA1308725C (de)
DE (1) DE3787333T2 (de)
ES (1) ES2059384T3 (de)
HU (1) HU197741B (de)
IL (1) IL83269A (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870169A (en) * 1985-07-17 1989-09-26 President And Fellows Of Harvard College Intermediates for beta-lactam antibiotics
JPH0733254B2 (ja) * 1990-02-27 1995-04-12 ソブエクレー株式会社 活性水酸化マグネシウムの製造方法
ATE305781T1 (de) 1996-02-23 2005-10-15 Lilly Co Eli Non-peptidische vasopressin via antagonisten
US5957712A (en) * 1997-07-30 1999-09-28 Thomas & Betts International, Inc. Loadbreak connector assembly which prevents switching flashover
CA2462903C (en) * 2001-10-12 2011-09-20 Serenix Pharmaceuticals, Llc Beta-lactamyl vasopressin v1a antagonists
WO2006102283A2 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
CN101268068B (zh) * 2005-07-19 2015-12-02 阿泽范药品公司 β-内酰胺基苯丙氨酸、半胱氨酸和丝氨酸血管加压素拮抗剂
WO2008012974A1 (fr) * 2006-07-28 2008-01-31 Kaneka Corporation Nouveau dérivé d'imidazolidinone, procédé de production de ce dérivé et procédé de production d'un acide aminé optiquement actif
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
PL2587919T3 (pl) 2010-07-01 2018-05-30 Azevan Pharmaceuticals, Inc. Sposoby leczenia zespołu stresu pourazowego
PL3122743T3 (pl) 2014-03-28 2023-05-02 Azevan Pharmaceuticals, Inc. Kompozycje i sposoby leczenia chorób neurodegeneracyjnych
TW201919625A (zh) 2017-09-15 2019-06-01 美商愛治凡製藥公司 用於治療腦損傷之組合物及方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487071A (en) * 1968-12-23 1969-12-30 Bristol Myers Co 3-blocked amino-delta**1,4-2-azetidinones
US3920696A (en) * 1973-04-02 1975-11-18 Lilly Co Eli 2s-carboxyalkylthio-3r-imidoazetidin-4-ones and compounds useful in their preparation
US4166816A (en) * 1975-05-05 1979-09-04 Smithkline Corporation Methods and intermediates for preparing cis-4-oxoazetidine intermediates
US4200572A (en) * 1975-09-03 1980-04-29 Smithkline Corporation Substituted azetidinones
US4565654A (en) * 1983-03-28 1986-01-21 University Of Notre Dame Du Lac N-Acyloxy monocyclic β-lactams
US4751299A (en) * 1983-11-18 1988-06-14 Takeda Chemical Industries, Ltd. Optically active β-lactams and method of their production

Also Published As

Publication number Publication date
JPS6335571A (ja) 1988-02-16
KR960000048B1 (ko) 1996-01-03
JPH0757752B2 (ja) 1995-06-21
ES2059384T3 (es) 1994-11-16
HUT45048A (en) 1988-05-30
EP0254578B1 (de) 1993-09-08
KR880001648A (ko) 1988-04-25
ATE94165T1 (de) 1993-09-15
EP0254578A1 (de) 1988-01-27
DE3787333D1 (de) 1993-10-14
IL83269A (en) 1991-12-15
HU197741B (en) 1989-05-29
US4772694A (en) 1988-09-20
CA1308725C (en) 1992-10-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee