ES2059384T3 - Intermedios de antibioticos. - Google Patents

Intermedios de antibioticos.

Info

Publication number
ES2059384T3
ES2059384T3 ES87306539T ES87306539T ES2059384T3 ES 2059384 T3 ES2059384 T3 ES 2059384T3 ES 87306539 T ES87306539 T ES 87306539T ES 87306539 T ES87306539 T ES 87306539T ES 2059384 T3 ES2059384 T3 ES 2059384T3
Authority
ES
Spain
Prior art keywords
antibiotics
azetidinones
intermediates
chlorides
aldimines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87306539T
Other languages
English (en)
Inventor
Robin David Grey Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2059384T3 publication Critical patent/ES2059384T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

CLORUROS DE OXAZOLIDIN-4-ONA-3-ILACETIL-2,5DISUSTITUIDOS Y CLORUROS DE IMIDAZOLIDIN-4-ONA-3-IL-ACETILO 1,2,5-SUSTITUIDOS COMO MITADES AUXILIARES QUIRALES EN LA CICLOADICION ASIMETRICA CON ALDIMINAS PARA PROPORCIONAR CISACETIDINONAS. LAS ACETIDINONAS RESULTAN PRODUCTOS INTERMEDIOS UTILES PARA LA PREPARACION DE ANTIBIOTICOS.
ES87306539T 1986-07-24 1987-07-23 Intermedios de antibioticos. Expired - Lifetime ES2059384T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/888,895 US4772694A (en) 1986-07-24 1986-07-24 Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates

Publications (1)

Publication Number Publication Date
ES2059384T3 true ES2059384T3 (es) 1994-11-16

Family

ID=25394125

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87306539T Expired - Lifetime ES2059384T3 (es) 1986-07-24 1987-07-23 Intermedios de antibioticos.

Country Status (10)

Country Link
US (1) US4772694A (es)
EP (1) EP0254578B1 (es)
JP (1) JPH0757752B2 (es)
KR (1) KR960000048B1 (es)
AT (1) ATE94165T1 (es)
CA (1) CA1308725C (es)
DE (1) DE3787333T2 (es)
ES (1) ES2059384T3 (es)
HU (1) HU197741B (es)
IL (1) IL83269A (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870169A (en) * 1985-07-17 1989-09-26 President And Fellows Of Harvard College Intermediates for beta-lactam antibiotics
JPH0733254B2 (ja) * 1990-02-27 1995-04-12 ソブエクレー株式会社 活性水酸化マグネシウムの製造方法
JP4212112B2 (ja) 1996-02-23 2009-01-21 イーライ・リリー・アンド・カンパニー 非ペプチジルバソプレッシンＶ１ａアンタゴニスト
US5957712A (en) * 1997-07-30 1999-09-28 Thomas & Betts International, Inc. Loadbreak connector assembly which prevents switching flashover
CN101921267A (zh) * 2001-10-12 2010-12-22 阿泽范药品公司 β-内酰胺后叶加压素V1a拮抗剂
WO2006102308A2 (en) 2005-03-22 2006-09-28 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin v1b antagonists
AU2006270039B2 (en) 2005-07-19 2013-07-04 Azevan Pharmaceuticals, Inc. Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists
US7947722B2 (en) 2006-07-28 2011-05-24 Kaneka Corporation Imidazolidinone derivative, method of producing the same and method of producing optically active amino acid
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
PL2587919T3 (pl) 2010-07-01 2018-05-30 Azevan Pharmaceuticals, Inc. Sposoby leczenia zespołu stresu pourazowego
BR112016022575A2 (pt) 2014-03-28 2017-08-15 Azevan Pharmaceuticals Inc Composições e métodos para o tratamento de doenças neurodegenerativas
BR112020005107A2 (pt) 2017-09-15 2020-11-03 Azevan Pharmaceuticals, Inc. composições e métodos para o tratamento de lesão cerebral

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487071A (en) * 1968-12-23 1969-12-30 Bristol Myers Co 3-blocked amino-delta**1,4-2-azetidinones
US3920696A (en) * 1973-04-02 1975-11-18 Lilly Co Eli 2s-carboxyalkylthio-3r-imidoazetidin-4-ones and compounds useful in their preparation
US4166816A (en) * 1975-05-05 1979-09-04 Smithkline Corporation Methods and intermediates for preparing cis-4-oxoazetidine intermediates
US4200572A (en) * 1975-09-03 1980-04-29 Smithkline Corporation Substituted azetidinones
US4565654A (en) * 1983-03-28 1986-01-21 University Of Notre Dame Du Lac N-Acyloxy monocyclic β-lactams
US4751299A (en) * 1983-11-18 1988-06-14 Takeda Chemical Industries, Ltd. Optically active β-lactams and method of their production

Also Published As

Publication number Publication date
IL83269A (en) 1991-12-15
JPS6335571A (ja) 1988-02-16
HU197741B (en) 1989-05-29
KR880001648A (ko) 1988-04-25
KR960000048B1 (ko) 1996-01-03
DE3787333T2 (de) 1994-02-03
HUT45048A (en) 1988-05-30
US4772694A (en) 1988-09-20
DE3787333D1 (de) 1993-10-14
EP0254578B1 (en) 1993-09-08
ATE94165T1 (de) 1993-09-15
EP0254578A1 (en) 1988-01-27
CA1308725C (en) 1992-10-13
JPH0757752B2 (ja) 1995-06-21

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