DE3750451D1 - Rekombinanter menschlicher endothelzellenwachstumsfaktor. - Google Patents

Rekombinanter menschlicher endothelzellenwachstumsfaktor.

Info

Publication number
DE3750451D1
DE3750451D1 DE3750451T DE3750451T DE3750451D1 DE 3750451 D1 DE3750451 D1 DE 3750451D1 DE 3750451 T DE3750451 T DE 3750451T DE 3750451 T DE3750451 T DE 3750451T DE 3750451 D1 DE3750451 D1 DE 3750451D1
Authority
DE
Germany
Prior art keywords
growth factor
cell growth
recombinant human
endothelial cell
endothel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3750451T
Other languages
English (en)
Other versions
DE3750451T2 (de
Inventor
Michael Jaye
Wilson Burgess
Thomas Maciag
William Drohan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CENTELION, VITRY SUR SEINE, FR
Original Assignee
Rhone Poulenc Rorer Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharmaceuticals Inc filed Critical Rhone Poulenc Rorer Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3750451D1 publication Critical patent/DE3750451D1/de
Publication of DE3750451T2 publication Critical patent/DE3750451T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE3750451T 1986-03-03 1987-03-02 Rekombinanter menschlicher endothelzellenwachstumsfaktor. Expired - Lifetime DE3750451T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/835,594 US4868113A (en) 1986-03-03 1986-03-03 Recombinant DNA vector encoding human endothelial cell growth factor
PCT/US1987/000425 WO1987005332A1 (en) 1986-03-03 1987-03-02 Recombinant human endothelial cell growth factor

Publications (2)

Publication Number Publication Date
DE3750451D1 true DE3750451D1 (de) 1994-10-06
DE3750451T2 DE3750451T2 (de) 1994-12-22

Family

ID=25269917

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3750451T Expired - Lifetime DE3750451T2 (de) 1986-03-03 1987-03-02 Rekombinanter menschlicher endothelzellenwachstumsfaktor.

Country Status (16)

Country Link
US (1) US4868113A (de)
EP (1) EP0259475B1 (de)
JP (4) JPS63502725A (de)
KR (1) KR960002874B1 (de)
AT (1) ATE110782T1 (de)
AU (1) AU617086B2 (de)
DE (1) DE3750451T2 (de)
DK (1) DK175807B1 (de)
FI (1) FI874819A (de)
HK (1) HK1002123A1 (de)
IE (1) IE66307B1 (de)
NZ (1) NZ219485A (de)
PH (1) PH24857A (de)
RU (1) RU1804480C (de)
UA (1) UA13321A (de)
WO (1) WO1987005332A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
WO1989000198A1 (en) * 1987-07-07 1989-01-12 Biotechnology Research Associates, J.V. Recombinant fibroblast growth factors
ATE105868T1 (de) * 1985-09-12 1994-06-15 Scios Nova Inc Rekombinanter fibroblast-wachstumsfaktor.
US5552528A (en) 1986-03-03 1996-09-03 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bovine b-endothelial cell growth factor
US5827826A (en) 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
NZ220917A (en) * 1986-07-11 1991-05-28 Merck & Co Inc Human and bovine acidic fibroblast growth factor vectors, hosts and compositions
NZ226543A (en) * 1987-10-22 1992-02-25 Merck & Co Inc Recombinant mutant acidic fibroblast growth factor
US5312911A (en) * 1987-10-22 1994-05-17 Merck & Co., Inc. Cysteine-modified acidic fibroblast growth factor
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
GB2223497B (en) * 1988-08-08 1992-04-01 British Bio Technology Synthetic gene encoding human beta endothelial cell growth factor
GB2223496B (en) * 1988-08-08 1992-05-27 British Bio Technology Synthetic gene encoding mature human acid fibroblast growth factor
US5656458A (en) * 1988-11-04 1997-08-12 Chiron Corporation Expression and processing of amino terminus acetylated FGF's in yeast
EP0441886B1 (de) * 1988-11-04 1996-08-21 Chiron Corporation EXPRESSION UND PROZESSIERUNG VON ACETYLIERTEN FGFs IN HEFEN
US5756686A (en) * 1988-12-20 1998-05-26 Ludwig Institute For Cancer Research Peptides derived from endothelial cell growth factor
US5227302A (en) * 1988-12-20 1993-07-13 Ludwig Institute For Cancer Research DNA encoding platelet derived endothelial cell growth factor (PD-ECGF)
ATE197800T1 (de) 1989-01-31 2000-12-15 Jeffrey S Rubin Dns kodierend für einen für epithelzellen spezifischen wachstumsfaktor
US7026291B1 (en) 1989-01-31 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
US5595887A (en) * 1990-07-16 1997-01-21 Bionebraska, Inc. Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
US5244460A (en) * 1991-11-27 1993-09-14 The United States Of America As Represented By The Department Of Health And Human Services Method to foster myocardial blood vessel growth and improve blood flow to the heart
US5348941A (en) * 1992-04-01 1994-09-20 Merck & Co., Inc. Stabilizers for fibroblast growth factors
US20050019824A1 (en) * 1994-03-08 2005-01-27 Human Genome Sciences, Inc. Fibroblast Growth Factor-10
US5656598A (en) * 1994-03-08 1997-08-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Use of fibroblast growth factors to stimulate bone growth
WO1995024211A1 (en) * 1994-03-08 1995-09-14 Osteosa, Inc. Use of fibroblast growth factors to stimulate bone growth
US5817485A (en) * 1994-03-08 1998-10-06 Human Genome Sciences, Inc. Nucleic acids and cells for recombinant production of fibroblast growth factor-10
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6110893A (en) * 1995-06-05 2000-08-29 Human Genome Sciences, Inc. Fibroblast growth factor 11
US6605441B1 (en) 1995-06-05 2003-08-12 Human Genome Sciences, Inc. Antibodies against fibroblast growth factor 11
US5763214A (en) * 1995-06-05 1998-06-09 Human Genome Sciences, Inc. Fibroblast growth factor 11
JPH11507697A (ja) * 1995-06-09 1999-07-06 エヌ． ドロハン，ウィリアム キチンヒドロゲル、それらの製造方法及び利用
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
US6645947B1 (en) * 1999-05-20 2003-11-11 Chitogenics, Inc. Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins
US6719805B1 (en) * 1999-06-09 2004-04-13 C. R. Bard, Inc. Devices and methods for treating tissue
DE60142351D1 (de) 2000-10-20 2010-07-22 Amylin Pharmaceuticals Inc Behandlung von hypoaktivem myokard und diabetischer herzmyopathie mit einem glp-1 peptid
US6982170B1 (en) 2001-12-17 2006-01-03 Maine Medical Center Research Institute Compositions, methods and kits relating to thrombin degradation resistant fibroblast growth factor-1
US7265097B2 (en) * 2002-08-20 2007-09-04 Chitogenics, Inc. Methods of drug delivery using sulphated chitinous polymers
ATE513823T1 (de) * 2004-08-17 2011-07-15 Simpson Biotech Co Ltd Mischung und verbindungen von mycelien von antrodia camphorata und deren verwendung
US8256429B2 (en) * 2005-05-18 2012-09-04 Cooltouch Incorporated Treatment of cellulite and adipose tissue with mid-infrared radiation
US8357146B2 (en) * 2005-05-18 2013-01-22 Cooltouch Incorporated Treatment of cellulite and adipose tissue with mid-infrared radiation
US8276590B2 (en) 2005-05-18 2012-10-02 Cooltouch Incorporated Thermally mediated tissue molding
US20070134204A1 (en) * 2005-12-09 2007-06-14 Henrich Cheng Method for treating nerve injury and vector construct for the same
JP2011121882A (ja) * 2009-12-09 2011-06-23 Eu Sol Biotech Co Ltd ヒト酸性繊維芽細胞増殖因子の改変ペプチド

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE105868T1 (de) * 1985-09-12 1994-06-15 Scios Nova Inc Rekombinanter fibroblast-wachstumsfaktor.

Also Published As

Publication number Publication date
KR960002874B1 (ko) 1996-02-27
US4868113A (en) 1989-09-19
ATE110782T1 (de) 1994-09-15
DE3750451T2 (de) 1994-12-22
EP0259475B1 (de) 1994-08-31
JP3273354B2 (ja) 2002-04-08
WO1987005332A1 (en) 1987-09-11
JPH10175999A (ja) 1998-06-30
JPH09135690A (ja) 1997-05-27
DK572487A (da) 1987-11-02
RU1804480C (ru) 1993-03-23
UA13321A (uk) 1997-02-28
EP0259475A4 (de) 1989-10-12
IE870535L (en) 1987-09-03
HK1002123A1 (en) 1998-07-31
AU617086B2 (en) 1991-11-21
EP0259475A1 (de) 1988-03-16
JPH09294590A (ja) 1997-11-18
JPS63502725A (ja) 1988-10-13
IE66307B1 (en) 1995-12-27
JP3372464B2 (ja) 2003-02-04
DK175807B1 (da) 2005-03-07
KR880700858A (ko) 1988-04-12
FI874819A0 (fi) 1987-11-02
AU7201287A (en) 1987-09-28
FI874819A (fi) 1987-11-02
PH24857A (en) 1990-12-26
DK572487D0 (da) 1987-11-02
NZ219485A (en) 1990-02-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMACEUTICALS PRODUCTS INC.(N.D.GES.D. S

8327 Change in the person/name/address of the patent owner

Owner name: GENCELL S.A., VITRY-SUR-SEINE, FR

8327 Change in the person/name/address of the patent owner

Owner name: CENTELION, VITRY SUR SEINE, FR