ATE110782T1 - Rekombinanter menschlicher endothelzellenwachstumsfaktor. - Google Patents

Rekombinanter menschlicher endothelzellenwachstumsfaktor.

Info

Publication number
ATE110782T1
ATE110782T1 AT87902208T AT87902208T ATE110782T1 AT E110782 T1 ATE110782 T1 AT E110782T1 AT 87902208 T AT87902208 T AT 87902208T AT 87902208 T AT87902208 T AT 87902208T AT E110782 T1 ATE110782 T1 AT E110782T1
Authority
AT
Austria
Prior art keywords
endothelial cell
growth factor
cell growth
recombinant human
human endothelial
Prior art date
Application number
AT87902208T
Other languages
English (en)
Inventor
Michael Jaye
Wilson Burgess
Thomas Maciag
William Drohan
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Application granted granted Critical
Publication of ATE110782T1 publication Critical patent/ATE110782T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT87902208T 1986-03-03 1987-03-02 Rekombinanter menschlicher endothelzellenwachstumsfaktor. ATE110782T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/835,594 US4868113A (en) 1986-03-03 1986-03-03 Recombinant DNA vector encoding human endothelial cell growth factor

Publications (1)

Publication Number Publication Date
ATE110782T1 true ATE110782T1 (de) 1994-09-15

Family

ID=25269917

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87902208T ATE110782T1 (de) 1986-03-03 1987-03-02 Rekombinanter menschlicher endothelzellenwachstumsfaktor.

Country Status (16)

Country Link
US (1) US4868113A (de)
EP (1) EP0259475B1 (de)
JP (4) JPS63502725A (de)
KR (1) KR960002874B1 (de)
AT (1) ATE110782T1 (de)
AU (1) AU617086B2 (de)
DE (1) DE3750451T2 (de)
DK (1) DK175807B1 (de)
FI (1) FI874819A0 (de)
HK (1) HK1002123A1 (de)
IE (1) IE66307B1 (de)
NZ (1) NZ219485A (de)
PH (1) PH24857A (de)
RU (1) RU1804480C (de)
UA (1) UA13321A (de)
WO (1) WO1987005332A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
WO1987001728A1 (en) * 1985-09-12 1987-03-26 Biotechnology Research Partners, Ltd. Recombinant fibroblast growth factors
US5552528A (en) * 1986-03-03 1996-09-03 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bovine b-endothelial cell growth factor
US5827826A (en) 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
NZ220917A (en) * 1986-07-11 1991-05-28 Merck & Co Inc Human and bovine acidic fibroblast growth factor vectors, hosts and compositions
JP2879148B2 (ja) * 1987-07-07 1999-04-05 サイオス インコーポレイテッド 組換え繊維芽細胞成長因子
US5312911A (en) * 1987-10-22 1994-05-17 Merck & Co., Inc. Cysteine-modified acidic fibroblast growth factor
NZ226543A (en) * 1987-10-22 1992-02-25 Merck & Co Inc Recombinant mutant acidic fibroblast growth factor
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
GB2223496B (en) * 1988-08-08 1992-05-27 British Bio Technology Synthetic gene encoding mature human acid fibroblast growth factor
GB2223497B (en) * 1988-08-08 1992-04-01 British Bio Technology Synthetic gene encoding human beta endothelial cell growth factor
US5656458A (en) * 1988-11-04 1997-08-12 Chiron Corporation Expression and processing of amino terminus acetylated FGF's in yeast
DE68927009T2 (de) * 1988-11-04 1997-04-03 Chiron Corp EXPRESSION UND PROZESSIERUNG VON ACETYLIERTEN FGFs IN HEFEN
US5227302A (en) * 1988-12-20 1993-07-13 Ludwig Institute For Cancer Research DNA encoding platelet derived endothelial cell growth factor (PD-ECGF)
US5756686A (en) * 1988-12-20 1998-05-26 Ludwig Institute For Cancer Research Peptides derived from endothelial cell growth factor
US7026291B1 (en) 1989-01-31 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
WO1990008771A1 (en) 1989-01-31 1990-08-09 Rubin Jeffrey S Dna encoding a growth factor specific for epithelial cells
US5595887A (en) * 1990-07-16 1997-01-21 Bionebraska, Inc. Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
US5244460A (en) * 1991-11-27 1993-09-14 The United States Of America As Represented By The Department Of Health And Human Services Method to foster myocardial blood vessel growth and improve blood flow to the heart
US5348941A (en) * 1992-04-01 1994-09-20 Merck & Co., Inc. Stabilizers for fibroblast growth factors
JPH09510209A (ja) * 1994-03-08 1997-10-14 オステオサ インコーポレイテッド 骨の成長を刺激するための繊維芽細胞成長因子の用途
US5817485A (en) * 1994-03-08 1998-10-06 Human Genome Sciences, Inc. Nucleic acids and cells for recombinant production of fibroblast growth factor-10
US5656598A (en) * 1994-03-08 1997-08-12 Rhone-Poulenc Rorer Pharmaceuticals Inc. Use of fibroblast growth factors to stimulate bone growth
US20050019824A1 (en) * 1994-03-08 2005-01-27 Human Genome Sciences, Inc. Fibroblast Growth Factor-10
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
JPH11506917A (ja) * 1995-06-05 1999-06-22 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 線維芽細胞増殖因子１１
US6110893A (en) * 1995-06-05 2000-08-29 Human Genome Sciences, Inc. Fibroblast growth factor 11
US6605441B1 (en) 1995-06-05 2003-08-12 Human Genome Sciences, Inc. Antibodies against fibroblast growth factor 11
CA2224253A1 (en) * 1995-06-09 1996-12-27 Martin J. Macphee Chitin hydrogels, methods of their production and use
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
US6645947B1 (en) * 1999-05-20 2003-11-11 Chitogenics, Inc. Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins
US6719805B1 (en) * 1999-06-09 2004-04-13 C. R. Bard, Inc. Devices and methods for treating tissue
WO2002034285A2 (en) 2000-10-20 2002-05-02 Coolidge Thomas R Treatment of hibernating myocardium and diabetic cardiomyopathy with a glp-1 peptide
US6982170B1 (en) 2001-12-17 2006-01-03 Maine Medical Center Research Institute Compositions, methods and kits relating to thrombin degradation resistant fibroblast growth factor-1
US7265097B2 (en) * 2002-08-20 2007-09-04 Chitogenics, Inc. Methods of drug delivery using sulphated chitinous polymers
ATE513823T1 (de) * 2004-08-17 2011-07-15 Simpson Biotech Co Ltd Mischung und verbindungen von mycelien von antrodia camphorata und deren verwendung
US8357146B2 (en) * 2005-05-18 2013-01-22 Cooltouch Incorporated Treatment of cellulite and adipose tissue with mid-infrared radiation
US8276590B2 (en) 2005-05-18 2012-10-02 Cooltouch Incorporated Thermally mediated tissue molding
US8256429B2 (en) 2005-05-18 2012-09-04 Cooltouch Incorporated Treatment of cellulite and adipose tissue with mid-infrared radiation
US20070134204A1 (en) * 2005-12-09 2007-06-14 Henrich Cheng Method for treating nerve injury and vector construct for the same
JP2011121882A (ja) * 2009-12-09 2011-06-23 Eu Sol Biotech Co Ltd ヒト酸性繊維芽細胞増殖因子の改変ペプチド

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001728A1 (en) * 1985-09-12 1987-03-26 Biotechnology Research Partners, Ltd. Recombinant fibroblast growth factors

Also Published As

Publication number Publication date
AU7201287A (en) 1987-09-28
EP0259475B1 (de) 1994-08-31
KR960002874B1 (ko) 1996-02-27
IE870535L (en) 1987-09-03
JPH10175999A (ja) 1998-06-30
DE3750451D1 (de) 1994-10-06
IE66307B1 (en) 1995-12-27
HK1002123A1 (en) 1998-07-31
UA13321A (uk) 1997-02-28
DK572487D0 (da) 1987-11-02
JPS63502725A (ja) 1988-10-13
DE3750451T2 (de) 1994-12-22
JPH09135690A (ja) 1997-05-27
PH24857A (en) 1990-12-26
EP0259475A1 (de) 1988-03-16
EP0259475A4 (de) 1989-10-12
DK175807B1 (da) 2005-03-07
RU1804480C (ru) 1993-03-23
DK572487A (da) 1987-11-02
JP3273354B2 (ja) 2002-04-08
NZ219485A (en) 1990-02-26
FI874819A (fi) 1987-11-02
FI874819A0 (fi) 1987-11-02
WO1987005332A1 (en) 1987-09-11
US4868113A (en) 1989-09-19
JP3372464B2 (ja) 2003-02-04
AU617086B2 (en) 1991-11-21
KR880700858A (ko) 1988-04-12
JPH09294590A (ja) 1997-11-18

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Legal Events

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EELA Cancelled due to lapse of time