DE3732688A1 - Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch - Google Patents

Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch

Info

Publication number
DE3732688A1
DE3732688A1 DE19873732688 DE3732688A DE3732688A1 DE 3732688 A1 DE3732688 A1 DE 3732688A1 DE 19873732688 DE19873732688 DE 19873732688 DE 3732688 A DE3732688 A DE 3732688A DE 3732688 A1 DE3732688 A1 DE 3732688A1
Authority
DE
Germany
Prior art keywords
reagent
turbidity
detergents
blood
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19873732688
Other languages
German (de)
English (en)
Inventor
Bernd Dr Med Vogt
Liselotte Schellong
Joachim Dr Rer Nat Siedel
Joachim Dr Rer Nat Ziegenhorn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE19873732688 priority Critical patent/DE3732688A1/de
Priority to EP88115456A priority patent/EP0309882A3/de
Priority to US07/249,381 priority patent/US5149633A/en
Priority to JP63239896A priority patent/JPH01108997A/ja
Publication of DE3732688A1 publication Critical patent/DE3732688A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/90—Developer
    • C12Q2326/92—Nitro blue tetrazolium chloride, i.e. NBT
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/904—Oxidation - reduction indicators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/173845—Amine and quaternary ammonium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Diabetes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE19873732688 1987-09-29 1987-09-29 Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch Withdrawn DE3732688A1 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE19873732688 DE3732688A1 (de) 1987-09-29 1987-09-29 Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch
EP88115456A EP0309882A3 (de) 1987-09-29 1988-09-21 Verfahren zur spezifischen Bestimmung des Serumfructosamingehalts sowie hierfür geeignetes Reagenzgemisch
US07/249,381 US5149633A (en) 1987-09-29 1988-09-26 Process and reagent for the specific determination of fructosamine content in blood and samples obtained from blood
JP63239896A JPH01108997A (ja) 1987-09-29 1988-09-27 血液又は血液から導出した試料中の血清のフルクトスアミン含量を特異的に測定する方法及び試薬、及び非特異的還元作用を有するか、又は／及び溷濁を惹起する試料成分を除去する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873732688 DE3732688A1 (de) 1987-09-29 1987-09-29 Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch

Publications (1)

Publication Number Publication Date
DE3732688A1 true DE3732688A1 (de) 1989-04-13

Family

ID=6337076

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873732688 Withdrawn DE3732688A1 (de) 1987-09-29 1987-09-29 Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch

Country Status (4)

Country Link
US (1) US5149633A (enExample)
EP (1) EP0309882A3 (enExample)
JP (1) JPH01108997A (enExample)
DE (1) DE3732688A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3920364A1 (de) * 1989-06-22 1991-01-10 Technicon Gmbh Verfahren und reagenz zur verhinderung von truebungen

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3822749A1 (de) * 1988-07-05 1990-01-11 Boehringer Mannheim Gmbh Fructosamin-calibrator
US5484735A (en) * 1989-08-23 1996-01-16 Northwestern University Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids
JP2796150B2 (ja) * 1989-12-20 1998-09-10 株式会社ヤトロン フルクトサミンの測定方法
GB9116315D0 (en) * 1991-07-29 1991-09-11 Genzyme Ltd Assay
CA2098956C (en) 1992-07-15 1999-12-07 Thomas Charles Arter Sulfhydryl-complexing agents in clinical test elements
CA2127679A1 (en) * 1993-07-27 1995-01-28 Ewald Vorberg Set of reagents for determining the fructosamine content
DE4401754A1 (de) * 1994-01-21 1995-07-27 Boehringer Mannheim Gmbh Verfahren und Reagenz zur Bestimmung von Eisen
US20120077278A1 (en) * 2009-06-08 2012-03-29 Protea Biopharma N.V. Methods and kits for detecting, diagnosing and monitoring diseases
CN114112595B (zh) * 2021-12-03 2024-08-20 威海威高生物科技有限公司 一种果糖胺测定试剂盒液体校准品的制备方法
CN115372605A (zh) * 2022-07-08 2022-11-22 北京常有生物科技有限公司 一种尿液巯基化合物检测试剂及检测试剂、检测试纸、检测试剂盒的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816229C2 (de) * 1978-04-14 1983-11-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Beseitigung von Trübungen
DE2907628C2 (de) * 1979-02-27 1981-02-05 C.A. Greiner Und Soehne Gmbh & Co Kg, 7440 Nuertingen Proberöhrchen für die Untersuchung von Proben im klinischen Bereich, insbesondere von Urinproben
DE2910737C2 (de) * 1979-03-19 1984-01-19 Ewald 6701 Dannstadt-Schauernheim Blees Verfahren zur Ausschaltung störender Begleitreaktionen bei enzymatischen Analysenverfahren
DE2914487A1 (de) * 1979-04-10 1980-10-30 Boehringer Mannheim Gmbh Verfahren und mittel zur entfernung von ascorbinsaeure aus waessrigen fluessigkeiten
US4271024A (en) * 1979-05-23 1981-06-02 Meyer Dairy Products, Co. Liquid filter
US4460684A (en) * 1982-08-02 1984-07-17 Miles Laboratories, Inc. Ascorbate-resistant broad range glucose test composition, test device and method
JPH0229318B2 (ja) * 1982-10-22 1990-06-28 Amano Pharma Co Ltd Seitaitaiekiseibunnosokuteiho
JPS59198971A (ja) * 1983-04-28 1984-11-10 Kyowa Hakko Kogyo Co Ltd ビリルビンオキシダ−ゼの製造法
US4626511A (en) * 1985-05-13 1986-12-02 Wayne State University Composition for reducing turbidity in samples of biological fluids
US5002893A (en) * 1985-09-19 1991-03-26 Isolab, Inc. Single color reading method for determining fructosamine
DE3620817A1 (de) * 1986-06-21 1987-12-23 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch
DE3743405A1 (de) * 1987-05-14 1988-11-24 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fructosamin
US4956301A (en) * 1989-11-02 1990-09-11 Miles Inc. Test device and method of assaying for fructosamines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3920364A1 (de) * 1989-06-22 1991-01-10 Technicon Gmbh Verfahren und reagenz zur verhinderung von truebungen

Also Published As

Publication number Publication date
EP0309882A3 (de) 1989-10-25
US5149633A (en) 1992-09-22
JPH01108997A (ja) 1989-04-26
EP0309882A2 (de) 1989-04-05
JPH0365760B2 (enExample) 1991-10-14

Similar Documents

Publication Publication Date Title
EP0250991B1 (de) Verfahren zur spezifischen Bestimmung des Serumfructosamingehalts sowie hierfür geeignetes Reagenzgemisch
DE3021259C2 (de) Mit Amidopyrin verbessertes Trinder-Reagens und Verfahren zur quantitativen Bestimmung von Wasserstoffperoxid bei der enzymatischen Oxidation von Stoffwechselprodukten mit diesem Reagens
EP0037056B1 (de) Verfahren und diagnostische Mittel zum Nachweis von Redox-Reaktionen
DE3788239T2 (de) Kontrollierte Farbton-Vorrichtung.
DE69021389T2 (de) Verfahren und reagenz zur bestimmung eines analyten auf enzymatischem wege mittels eines eisen-iii-zyan /eisen -iii-verbindungssystems.
DE69603472T2 (de) Bestimmung von glykierten proteinen
DE69229629T2 (de) Stabilisierung eines enzym enthaltenden reagenz zur bestimmung eines analyten
EP0012184A1 (de) Hämolysierlösung, Verwendung einer solchen für die Bestimmung von Glucose im Blut, und Hämolyseverfahren
DE2653537C3 (de) Verfahren und Mittel zur Bestimmung von Hydroperoxiden
EP0077515B1 (de) Verfahren und Reagenz zur Bestimmung von glykosiliertem Hämoglobin
EP0291060B1 (de) Verfahren zur Bestimmung von Fructosamin
EP0309882A2 (de) Verfahren zur spezifischen Bestimmung des Serumfructosamingehalts sowie hierfür geeignetes Reagenzgemisch
DE69228554T2 (de) Reagenzien und untersuchungsverfahren einschliesslich eines phenazin enthaltenden indikators
DE69026611T2 (de) Verfahren zur Bestimmung von Fruktosaminen
DE3408062A1 (de) Verfahren zur bestimmung von ss-hydroxibuttersaeure und eine zusammensetzung zur bestimmung von ss-hydroxibuttersaeure
DE3125667C2 (de) Verfahren und Mittel zum Nachweis von Wasserstoffperoxid
DE2459087C3 (de) Verfahren und Reagenz zur Bestimmung von Serumtriglyceriden
DE69433003T2 (de) Assayverfahren für biologische Komponenten
DE69430410T2 (de) Methode zum Nachweis von Fructosamin
EP0105443B1 (de) Verfahren zur selektiven Herstellung reduzierter Sauerstoffspezies und hierfür geeignete Reagentien
DE3329952A1 (de) Verfahren zur verringerung einer truebung in kontrollseren
CH646792A5 (de) Testvorrichtung fuer die bestimmung von harnsaeure.
EP0351790B1 (de) Verfahren zur Bestimmung von Fructosamin
EP0294714B1 (de) Verwendung von Polyvinylpyrrolidon (PVP) zur Trübungsminderung von Seren, Seren enthaltend PVP und Verfahren zu deren Herstellung
DE69620874T2 (de) Verfahren zur bestimmung von mit schwefelsäure konjugierter gallensäure und testsatz dafür

Legal Events

Date Code Title Description
8141 Disposal/no request for examination