DE3727894C2 - - Google Patents

Info

Publication number
DE3727894C2
DE3727894C2 DE3727894A DE3727894A DE3727894C2 DE 3727894 C2 DE3727894 C2 DE 3727894C2 DE 3727894 A DE3727894 A DE 3727894A DE 3727894 A DE3727894 A DE 3727894A DE 3727894 C2 DE3727894 C2 DE 3727894C2
Authority
DE
Germany
Prior art keywords
capsule
ingredients
phase
features
constituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3727894A
Other languages
German (de)
English (en)
Other versions
DE3727894A1 (de
Inventor
Dieter Dr. Stephan
Guenter 7000 Stuttgart De Stephan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19873727894 priority Critical patent/DE3727894A1/de
Priority to EP88112688A priority patent/EP0308637A1/de
Priority to FI883785A priority patent/FI883785L/fi
Priority to DK457288A priority patent/DK457288A/da
Priority to NO88883667A priority patent/NO883667L/no
Publication of DE3727894A1 publication Critical patent/DE3727894A1/de
Application granted granted Critical
Publication of DE3727894C2 publication Critical patent/DE3727894C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Package Specialized In Special Use (AREA)
DE19873727894 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge Granted DE3727894A1 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
EP88112688A EP0308637A1 (de) 1987-08-21 1988-08-04 Kapsel für pharmazeutisch wirksame Inhaltsstoffe einer Droge
FI883785A FI883785L (fi) 1987-08-21 1988-08-16 Kapsel foer farmaceutiskt verksamt inhaleringsaemne i ett laekemedel.
DK457288A DK457288A (da) 1987-08-21 1988-08-16 Kapsel til farmaceutisk virksomme stoffer
NO88883667A NO883667L (no) 1987-08-21 1988-08-17 Kapsel for farmasoeytisk virksomme innholdsstoffer av en droge.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Publications (2)

Publication Number Publication Date
DE3727894A1 DE3727894A1 (de) 1989-03-02
DE3727894C2 true DE3727894C2 (enExample) 1990-07-05

Family

ID=6334182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873727894 Granted DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Country Status (5)

Country Link
EP (1) EP0308637A1 (enExample)
DE (1) DE3727894A1 (enExample)
DK (1) DK457288A (enExample)
FI (1) FI883785L (enExample)
NO (1) NO883667L (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) * 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
GB2338896B (en) 1998-07-02 2003-05-21 Reckitt & Colmann Prod Ltd Chewable Capsules
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
DK1649886T3 (da) * 1999-07-23 2008-05-05 Mannkind Corp Enhedsdosiskapsler til törpulverinhalatorer
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
MY142179A (en) 2002-07-25 2010-10-15 Glaxo Group Ltd Multicomponent pharmaceutical dosage form
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
EP1682063A1 (en) 2003-10-21 2006-07-26 Ambo Innovation LLC Digestible and volume adjustable multi medication delivery device
GB0402285D0 (en) * 2004-02-03 2004-03-10 Hasirci Billy S Product for administering medication
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
EP1836665B1 (en) 2004-11-19 2013-01-16 GlaxoSmithKline LLC Method for customized dispensing of variable dose drug combination products for individualizing of therapies
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
CA2625776A1 (en) * 2005-10-14 2007-04-26 Microdose Technologies, Inc. Pharmaceutical packaging of an oral dosage combination
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
WO2008113368A1 (en) * 2007-03-21 2008-09-25 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
EP2219583B1 (en) 2007-10-15 2012-11-21 Capsugel Belgium NV Method and apparatus for manufacturing filled linkers
CN101827571A (zh) 2007-10-15 2010-09-08 葛兰素集团有限公司 用于释放一种或多种药物成分的多部分剂型的连接件及所得剂型
EP2209455A1 (en) 2007-10-15 2010-07-28 Glaxo Group Limited Paneled capsule shells for release of pharmaceutical compositions
EP2219624A2 (en) 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN105381524A (zh) 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX363959B (es) 2011-10-06 2019-04-09 Combocap Inc Un metodo y aparato para fabricar una capsula.
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7610038A (en) * 1976-09-09 1978-03-13 Tapanahony N V Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively
WO1986004501A1 (fr) * 1985-01-31 1986-08-14 Fujisawa Pharmaceutical Co., Ltd. Capsule souple a cavites multiples; son procede et appareil de fabrication
DE3543154A1 (de) * 1985-12-06 1987-06-11 Boehringer Ingelheim Kg Teilbare kapsel

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations

Also Published As

Publication number Publication date
NO883667L (no) 1989-02-22
DK457288D0 (da) 1988-08-16
FI883785A7 (fi) 1989-02-22
DE3727894A1 (de) 1989-03-02
DK457288A (da) 1989-02-22
EP0308637A1 (de) 1989-03-29
NO883667D0 (no) 1988-08-17
FI883785A0 (fi) 1988-08-16
FI883785L (fi) 1989-02-22

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee