DE3727894C2 - - Google Patents

Info

Publication number
DE3727894C2
DE3727894C2 DE3727894A DE3727894A DE3727894C2 DE 3727894 C2 DE3727894 C2 DE 3727894C2 DE 3727894 A DE3727894 A DE 3727894A DE 3727894 A DE3727894 A DE 3727894A DE 3727894 C2 DE3727894 C2 DE 3727894C2
Authority
DE
Germany
Prior art keywords
capsule
ingredients
phase
features
constituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3727894A
Other languages
German (de)
English (en)
Other versions
DE3727894A1 (de
Inventor
Dieter Dr. Stephan
Guenter 7000 Stuttgart De Stephan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19873727894 priority Critical patent/DE3727894A1/de
Priority to EP88112688A priority patent/EP0308637A1/de
Priority to DK457288A priority patent/DK457288A/da
Priority to FI883785A priority patent/FI883785L/fi
Priority to NO88883667A priority patent/NO883667L/no
Publication of DE3727894A1 publication Critical patent/DE3727894A1/de
Application granted granted Critical
Publication of DE3727894C2 publication Critical patent/DE3727894C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Package Specialized In Special Use (AREA)
DE19873727894 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge Granted DE3727894A1 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
EP88112688A EP0308637A1 (de) 1987-08-21 1988-08-04 Kapsel für pharmazeutisch wirksame Inhaltsstoffe einer Droge
DK457288A DK457288A (da) 1987-08-21 1988-08-16 Kapsel til farmaceutisk virksomme stoffer
FI883785A FI883785L (fi) 1987-08-21 1988-08-16 Kapsel foer farmaceutiskt verksamt inhaleringsaemne i ett laekemedel.
NO88883667A NO883667L (no) 1987-08-21 1988-08-17 Kapsel for farmasoeytisk virksomme innholdsstoffer av en droge.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Publications (2)

Publication Number Publication Date
DE3727894A1 DE3727894A1 (de) 1989-03-02
DE3727894C2 true DE3727894C2 (enExample) 1990-07-05

Family

ID=6334182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873727894 Granted DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Country Status (5)

Country Link
EP (1) EP0308637A1 (enExample)
DE (1) DE3727894A1 (enExample)
DK (1) DK457288A (enExample)
FI (1) FI883785L (enExample)
NO (1) NO883667L (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) * 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
GB2338896B (en) * 1998-07-02 2003-05-21 Reckitt & Colmann Prod Ltd Chewable Capsules
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
ES2275544T3 (es) * 1999-07-23 2007-06-16 Mannkind Corporation Inhalador de polvo seco.
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
SI1494732T1 (sl) 2002-03-20 2008-08-31 Mannking Corp Inhalacijski aparat
AR040672A1 (es) 2002-07-25 2005-04-13 Glaxo Group Ltd Forma de dosificacion farmaceutica multicomponenete, cuerpo apropiado para ser utilizado en la misma y procedimiento para prepararla
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
EP1682063A1 (en) * 2003-10-21 2006-07-26 Ambo Innovation LLC Digestible and volume adjustable multi medication delivery device
GB0402285D0 (en) * 2004-02-03 2004-03-10 Hasirci Billy S Product for administering medication
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
JP5258297B2 (ja) 2004-11-19 2013-08-07 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 個人別に療法を合わせるために可変用量の薬物併用製品を特注で調剤する方法
EP2656836B1 (en) 2005-09-14 2017-07-26 MannKind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
EP1933815A2 (en) * 2005-10-14 2008-06-25 Microdose Technologies Inc. Pharmaceutical packaging of an oral dosage combination
US8039431B2 (en) 2006-02-22 2011-10-18 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
EP2134328A1 (en) * 2007-03-21 2009-12-23 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
WO2009050192A1 (en) 2007-10-15 2009-04-23 Glaxo Group Limited Paneled capsule shells for release of pharmaceutical compositions
WO2009050193A1 (en) 2007-10-15 2009-04-23 Glaxo Group Limited Method and apparatus for manufacturing filled linkers
EP2209456B1 (en) 2007-10-15 2013-03-06 Capsugel Belgium NV Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms
JP2011503048A (ja) 2007-11-08 2011-01-27 グラクソ グループ リミテッド 医薬製剤
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CA3086027C (en) 2008-06-13 2022-05-17 Mannkind Corporation A dry powder inhaler and system for drug delivery
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
KR20180079458A (ko) 2009-06-12 2018-07-10 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
PH12012501114A1 (en) 2010-01-05 2024-06-03 Microdose Therapeutx Inc Inhalation device and method
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
ES2596222T3 (es) 2011-10-06 2017-01-05 Binutra Incorporated Método y aparato para fabricar una cápsula
JP6018640B2 (ja) 2011-10-24 2016-11-02 マンカインド コーポレイション 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
JP6523247B2 (ja) 2013-03-15 2019-05-29 マンカインド コーポレイション 微結晶性ジケトピペラジン粒子の製造方法および乾燥粉末組成物の製造方法
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
BR122019026637B1 (pt) 2013-07-18 2023-09-26 Mannkind Corporation Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7610038A (en) * 1976-09-09 1978-03-13 Tapanahony N V Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively
WO1986004501A1 (fr) * 1985-01-31 1986-08-14 Fujisawa Pharmaceutical Co., Ltd. Capsule souple a cavites multiples; son procede et appareil de fabrication
DE3543154A1 (de) * 1985-12-06 1987-06-11 Boehringer Ingelheim Kg Teilbare kapsel

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations

Also Published As

Publication number Publication date
EP0308637A1 (de) 1989-03-29
FI883785A0 (fi) 1988-08-16
FI883785A7 (fi) 1989-02-22
NO883667D0 (no) 1988-08-17
FI883785L (fi) 1989-02-22
DE3727894A1 (de) 1989-03-02
DK457288A (da) 1989-02-22
NO883667L (no) 1989-02-22
DK457288D0 (da) 1988-08-16

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee