DE3727894C2 - - Google Patents

Info

Publication number
DE3727894C2
DE3727894C2 DE3727894A DE3727894A DE3727894C2 DE 3727894 C2 DE3727894 C2 DE 3727894C2 DE 3727894 A DE3727894 A DE 3727894A DE 3727894 A DE3727894 A DE 3727894A DE 3727894 C2 DE3727894 C2 DE 3727894C2
Authority
DE
Germany
Prior art keywords
capsule
ingredients
phase
features
constituents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3727894A
Other languages
German (de)
English (en)
Other versions
DE3727894A1 (de
Inventor
Dieter Dr. Stephan
Guenter 7000 Stuttgart De Stephan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19873727894 priority Critical patent/DE3727894A1/de
Priority to EP88112688A priority patent/EP0308637A1/de
Priority to DK457288A priority patent/DK457288A/da
Priority to FI883785A priority patent/FI883785L/fi
Priority to NO88883667A priority patent/NO883667L/no
Publication of DE3727894A1 publication Critical patent/DE3727894A1/de
Application granted granted Critical
Publication of DE3727894C2 publication Critical patent/DE3727894C2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Package Specialized In Special Use (AREA)
DE19873727894 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge Granted DE3727894A1 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge
EP88112688A EP0308637A1 (de) 1987-08-21 1988-08-04 Kapsel für pharmazeutisch wirksame Inhaltsstoffe einer Droge
DK457288A DK457288A (da) 1987-08-21 1988-08-16 Kapsel til farmaceutisk virksomme stoffer
FI883785A FI883785L (fi) 1987-08-21 1988-08-16 Kapsel foer farmaceutiskt verksamt inhaleringsaemne i ett laekemedel.
NO88883667A NO883667L (no) 1987-08-21 1988-08-17 Kapsel for farmasoeytisk virksomme innholdsstoffer av en droge.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873727894 DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Publications (2)

Publication Number Publication Date
DE3727894A1 DE3727894A1 (de) 1989-03-02
DE3727894C2 true DE3727894C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-07-05

Family

ID=6334182

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873727894 Granted DE3727894A1 (de) 1987-08-21 1987-08-21 Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge

Country Status (5)

Country Link
EP (1) EP0308637A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3727894A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK457288A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI883785L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO883667L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325445D0 (en) * 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
GB2338896B (en) * 1998-07-02 2003-05-21 Reckitt & Colmann Prod Ltd Chewable Capsules
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DK1923087T3 (da) * 1999-07-23 2012-12-03 Mannkind Corp Enhedsdosiskapsler til tørpulverinhalator
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
MY142179A (en) 2002-07-25 2010-10-15 Glaxo Group Ltd Multicomponent pharmaceutical dosage form
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
EP1682063A1 (en) * 2003-10-21 2006-07-26 Ambo Innovation LLC Digestible and volume adjustable multi medication delivery device
GB0402285D0 (en) * 2004-02-03 2004-03-10 Hasirci Billy S Product for administering medication
MX2007001903A (es) 2004-08-20 2007-08-02 Mannkind Corp Catalisis de sintesis de dicetopiperazina.
ES2540853T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
PT1836665E (pt) 2004-11-19 2013-04-11 Glaxosmithkline Llc Método para fornecimento personalizado de produtos de combinação de medicamentos em doses variáveis para individualização de terapêuticas
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
JP2009511191A (ja) * 2005-10-14 2009-03-19 マイクロドース・テクノロジーズ・インコーポレーテッド 経口投与剤組合せ型医薬パッケージ法
RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
WO2008113368A1 (en) * 2007-03-21 2008-09-25 Kariem Ezzat Mahmoud A gelatin capsule with extra cap for combined therapies
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
EP2209456B1 (en) 2007-10-15 2013-03-06 Capsugel Belgium NV Linkers for multipart dosage forms for release of one or more pharmaceutical compositions, and the resulting dosage forms
WO2009050193A1 (en) 2007-10-15 2009-04-23 Glaxo Group Limited Method and apparatus for manufacturing filled linkers
EP2209455A1 (en) 2007-10-15 2010-07-28 Glaxo Group Limited Paneled capsule shells for release of pharmaceutical compositions
JP2011503048A (ja) 2007-11-08 2011-01-27 グラクソ グループ リミテッド 医薬製剤
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
MY155524A (en) 2008-06-13 2015-10-30 Mannkind Corp A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
BR122020002400B1 (pt) 2008-06-20 2021-12-07 Mannkind Corporation Sistema de detecção de inalação de pó seco e sistema de monitoramento acoplável para um inalador de pó seco
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
JP6017961B2 (ja) 2010-01-05 2016-11-02 マイクロドース セラピューテクス，インコーポレイテッド 吸入デバイスおよび方法
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
JP6195173B2 (ja) 2011-10-06 2017-09-13 コンボキャップ，インコーポレイティド カプセルを製造する方法および装置
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
US9456987B2 (en) 2013-04-03 2016-10-04 Binutra, Inc. Capsule with internal diaphragm
JP6491658B2 (ja) 2013-07-18 2019-03-27 マンカインド コーポレイション 熱安定性乾燥粉末医薬組成物及び方法
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7610038A (en) * 1976-09-09 1978-03-13 Tapanahony N V Multichambered capsule for therapeutically active substances - has chambers of different solubility with contents differing quantitatively and qualitatively
EP0211079A4 (en) * 1985-01-31 1988-02-15 Fujisawa Pharmaceutical Co BENDABLE CAPSULE WITH SEVERAL CHAMBERS, METHOD AND DEVICE FOR THEIR PRODUCTION.
DE3543154A1 (de) * 1985-12-06 1987-06-11 Boehringer Ingelheim Kg Teilbare kapsel

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8440224B2 (en) 1999-07-30 2013-05-14 Capsugel Belgium Nv Multi-component pharmaceutical dosage form
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
US8361498B2 (en) 2001-01-30 2013-01-29 Capsugel Belgium Nv Pharmaceutical formulation
US8367101B2 (en) 2001-01-30 2013-02-05 Capsugel Belgium Nv Pharmaceutical formulation
US8147871B2 (en) 2004-03-12 2012-04-03 Capsugel Belgium Bvba Pharmaceutical formulations

Also Published As

Publication number Publication date
NO883667L (no) 1989-02-22
DK457288A (da) 1989-02-22
FI883785A7 (fi) 1989-02-22
EP0308637A1 (de) 1989-03-29
FI883785L (fi) 1989-02-22
FI883785A0 (fi) 1988-08-16
DE3727894A1 (de) 1989-03-02
DK457288D0 (da) 1988-08-16
NO883667D0 (no) 1988-08-17

Similar Documents

Publication Publication Date Title
DE3727894C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE69303434T2 (de) Behälter für pharmazeutische Produkte aus zwei gesonderten Komponenten, mit Mitteln zu deren Mischung und dosierter Ausgabe
DE4232062B4 (de) Dentalzement-Mischkapsel
DE68905752T2 (de) Zum Ändern der Zusammensetzung einer Flüssigkeit bestimmte Verpackung.
DE69424310T2 (de) Pulverinhalator
DE69405579T2 (de) Verfahren und vorrichtung zum zuführen von bestandteilen von knochenzement in einen mischbehälter,wo sie gemischt werden
DE69301448T2 (de) Injektionsvorrichtung
DE69317216T2 (de) Vorrichtung zum Dosieren von pharmazeutischem, mehrfachdosiertem Sirup für die Zubereitung an Orte und Stelle
DE2922706A1 (de) Vorrichtung zur vorbereitungsfreien herstellung einer loesung unter sterilen bedingungen
EP1027165A2 (de) Verfahren zum ausbringen von wenigstens zwei verschiedenen medien und spender dafür
EP0699594A1 (de) Zweikammerbehälter
DE69301152T2 (de) Behälter für eine Einzeldosis eines trinkbaren Produktes
EP0634336B1 (de) Zweikammer-Behältnis
DE2746489C2 (de) Verfahren zum Herstellen von Mikrokapseln mit Flüssigkeits- und/oder mit Feststoff-Füllungen durch Sprühtrocknung unter Verwendung einer Dreifachdüse
EP0245575A1 (de) Filterkörper, insbesondere mit Tee oder dergleichen Stoffen gefüllter Filterbeutel
DE3537748A1 (de) Verbesserte kapselform
DE19859499C2 (de) Stabile Ingwerextraktzubereitung
DE2625175C3 (de) Behälter-Verschluß mit Wirkstoff kammer
DE2650649A1 (de) Verfahren und vorrichtung zum fuellen und verschliessen von hartgelatinekapseln
DE1617522A1 (de) Verfahren zur Herstellung einer Arzneimittelzubereitung
DE3818022C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE3833458C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE3606003C2 (de) Doppelkammer-Behälter
DE60001656T2 (de) Behälter zur getrennten aufbewahrung von zwei mischfähigen komponenten
EP0644719B1 (de) Wasserlösliches instanttee-erzeugnis

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee