DE3690457T1 - - Google Patents

Info

Publication number
DE3690457T1
DE3690457T1 DE19863690457 DE3690457T DE3690457T1 DE 3690457 T1 DE3690457 T1 DE 3690457T1 DE 19863690457 DE19863690457 DE 19863690457 DE 3690457 T DE3690457 T DE 3690457T DE 3690457 T1 DE3690457 T1 DE 3690457T1
Authority
DE
Germany
Prior art keywords
hydroxydihydronormorphine
desoxy
cyclopropylmethyl
methylene
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19863690457
Other languages
German (de)
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Branded Pharmaceutical Products R&D Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of DE3690457T1 publication Critical patent/DE3690457T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19863690457 1985-09-06 1986-09-08 Withdrawn DE3690457T1 (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77321385A 1985-09-06 1985-09-06

Publications (1)

Publication Number Publication Date
DE3690457T1 true DE3690457T1 (enExample) 1987-08-06

Family

ID=25097554

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19863690457 Withdrawn DE3690457T1 (enExample) 1985-09-06 1986-09-08
DE8686906052T Expired - Lifetime DE3687575T2 (de) 1985-09-06 1986-09-08 Verwendung von 6-methylen-6-desoxy-n-cyclopropylmethyl-14-hydroxydihydronormorphin.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8686906052T Expired - Lifetime DE3687575T2 (de) 1985-09-06 1986-09-08 Verwendung von 6-methylen-6-desoxy-n-cyclopropylmethyl-14-hydroxydihydronormorphin.

Country Status (5)

Country Link
EP (1) EP0236477B1 (enExample)
JP (1) JPS63500799A (enExample)
AT (1) ATE84717T1 (enExample)
DE (2) DE3690457T1 (enExample)
WO (1) WO1987001282A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2412409T3 (es) 1997-12-22 2013-07-11 Euro-Celtique S.A. Forma farmacéutica para dosificación oral que comprende una combinación de un agonista opiáceo y un antagonista opiáceo
SI1299104T1 (sl) 2000-02-08 2009-10-31 Euro Celtique Sa Oralne formulacije opioidnih agonistov, varne pred zlorabo
US20030065002A1 (en) 2001-05-11 2003-04-03 Endo Pharmaceuticals, Inc. Abuse-resistant controlled-release opioid dosage form
US7914818B2 (en) 2001-08-06 2011-03-29 Purdue Pharma L.P. Opioid agonist formulations with releasable and sequestered antagonist
ES2320748T5 (es) 2002-04-05 2017-02-20 Euro-Celtique S.A. Matriz para la liberación sostenida, invariable e independiente de compuestos activos
EP2422773A3 (en) 2002-09-20 2012-04-18 Alpharma, Inc. Sequestering subunit and related compositions and methods
MY135852A (en) 2003-04-21 2008-07-31 Euro Celtique Sa Pharmaceutical products
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
ES2636657T3 (es) 2006-06-19 2017-10-06 Alpharma Pharmaceuticals Llc Composición farmacéutica
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
UY32487A (es) 2009-03-10 2010-06-30 Euro Celtique Sa Composiciones farmacéuticas de liberación inmediata comprendiendo oxicodona y naloxona
UA116567C2 (uk) 2013-07-23 2018-04-10 Євро-Селтік С.А. Комбінація оксикодону та налоксону для застосування в лікуванні болю у пацієнтів, які страждають від болю та захворювання, що призводить до дисбактеріозу кишечнику та/або підвищує ризик кишкової бактеріальної транслокації

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB769517A (en) * 1953-10-20 1957-03-06 Merck & Co Inc Analgesic compositions
US3493657A (en) * 1961-03-14 1970-02-03 Mozes Juda Lewenstein Therapeutic compositions of n-allyl-14-hydroxy - dihydronormorphinane and morphine
US3814768A (en) * 1971-11-26 1974-06-04 Lewenstein E 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts
US4322426A (en) * 1980-04-28 1982-03-30 E. I. Du Pont De Nemours And Company 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
JPS59500418A (ja) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ 胃腸能動作用障害を回復する方法
US4567185A (en) * 1983-05-13 1986-01-28 Key Pharmaceuticals, Inc. Endorphin blockage
US4535157A (en) * 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
GB8332556D0 (en) * 1983-12-06 1984-01-11 Reckitt & Colmann Prod Ltd Analgesic compositions

Also Published As

Publication number Publication date
EP0236477A1 (en) 1987-09-16
EP0236477B1 (en) 1993-01-20
WO1987001282A3 (en) 1987-08-13
DE3687575T2 (de) 1993-07-01
ATE84717T1 (de) 1993-02-15
JPS63500799A (ja) 1988-03-24
WO1987001282A2 (en) 1987-03-12
DE3687575D1 (de) 1993-03-04

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: IVAX LABORATORIES INC., MIAMI, FLA., US

8128 New person/name/address of the agent

Representative=s name: SCHOENWALD, K., DR.-ING. VON KREISLER, A., DIPL.-C

8127 New person/name/address of the applicant

Owner name: BAKER CUMMINS PHARMACEUTICALS, INC., MIAMI, FLA.,

8139 Disposal/non-payment of the annual fee