ES2003687A6 - Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina. - Google Patents

Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina.

Info

Publication number
ES2003687A6
ES2003687A6 ES8700425A ES8700425A ES2003687A6 ES 2003687 A6 ES2003687 A6 ES 2003687A6 ES 8700425 A ES8700425 A ES 8700425A ES 8700425 A ES8700425 A ES 8700425A ES 2003687 A6 ES2003687 A6 ES 2003687A6
Authority
ES
Spain
Prior art keywords
suspensions
amoxicillin
injectable
injectable amoxicillin
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700425A
Other languages
English (en)
Inventor
Abraham Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES2003687A6 publication Critical patent/ES2003687A6/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UN PREPARADO FARMACEUTICO INYECTABLE DE AMOXICILINA, CONSISTE EN MOLES EL TRIHIDRATO DE AMOXICILINA HASTA OBTENER UN POLVO FINO CON UN TAMAÑO DE PARTICULAS COMPRENDIDO ENTRE 1 Y 25 MICRONES Y A CONTINUACION SUSPENDERLO EN UN DISOLVENTE ADECUADO TAL COMO AGUA. LA CONCENTRACION DEL TRIHIDRATO DE AMOXICILINA EN EL PREPARADO INYECTABLE OSCILA ENTRE 100 MG DE ACTIVIDAD/ML Y 1.000 MG DE ACTIVIDAD/ML. EL PREPARADO INYECTABLE DE LA INVENCION TIENE APLICACION EN LA INDUSTRIA FARMACEUTICA YA QUE LA AMOXICILINA ES UN CONOCIDO ANTIBIOTICO DE AMPLIO ESPECTRO.
ES8700425A 1986-02-20 1987-02-19 Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina. Expired ES2003687A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8602332A FR2594334B1 (fr) 1986-02-20 1986-02-20 Composition pharmaceutique injectable a base d'amoxicilline

Publications (1)

Publication Number Publication Date
ES2003687A6 true ES2003687A6 (es) 1988-11-01

Family

ID=9332343

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700425A Expired ES2003687A6 (es) 1986-02-20 1987-02-19 Un procedimiento para la preparacion de un preparado farmaceutico inyectable de amoxicilina.

Country Status (13)

Country Link
BE (1) BE1000535A4 (es)
CH (1) CH668706A5 (es)
DE (1) DE3705349A1 (es)
EG (1) EG18455A (es)
ES (1) ES2003687A6 (es)
FR (1) FR2594334B1 (es)
GB (1) GB2186797B (es)
GR (1) GR870278B (es)
IT (1) IT1202567B (es)
LU (1) LU86781A1 (es)
MY (1) MY101146A (es)
NL (1) NL8700416A (es)
ZA (1) ZA871225B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1720533B1 (en) * 2004-02-24 2015-03-25 Sandoz Ag Amoxicillin instant granulate
CN102614294B (zh) * 2011-01-27 2015-02-25 瑞普(天津)生物药业有限公司 一种复方阿莫西林混悬注射剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3969524A (en) * 1974-08-13 1976-07-13 Hoffmann-La Roche Inc. Stable amoxicillin dosage form
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
GB1532993A (en) * 1975-03-07 1978-11-22 Beecham Group Ltd Injectable antibiotic compositions
FR2469179A1 (fr) * 1979-11-08 1981-05-22 Beecham Group Ltd Composition pharmaceutique pour injection renfermant une penicilline
DE3266580D1 (en) * 1981-12-02 1985-10-31 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics

Also Published As

Publication number Publication date
EG18455A (en) 1992-12-30
LU86781A1 (fr) 1987-09-15
DE3705349A1 (de) 1987-08-27
FR2594334B1 (fr) 1990-01-12
CH668706A5 (fr) 1989-01-31
GB2186797A (en) 1987-08-26
GB2186797B (en) 1990-01-24
IT8719426A0 (it) 1987-02-19
GR870278B (en) 1987-06-16
FR2594334A1 (fr) 1987-08-21
NL8700416A (nl) 1987-09-16
GB8703883D0 (en) 1987-03-25
ZA871225B (en) 1987-10-28
IT1202567B (it) 1989-02-09
BE1000535A4 (fr) 1989-01-24
MY101146A (en) 1991-07-31

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20110225