FR2469179A1 - Composition pharmaceutique pour injection renfermant une penicilline - Google Patents
Composition pharmaceutique pour injection renfermant une penicillineInfo
- Publication number
- FR2469179A1 FR2469179A1 FR8014623A FR8014623A FR2469179A1 FR 2469179 A1 FR2469179 A1 FR 2469179A1 FR 8014623 A FR8014623 A FR 8014623A FR 8014623 A FR8014623 A FR 8014623A FR 2469179 A1 FR2469179 A1 FR 2469179A1
- Authority
- FR
- France
- Prior art keywords
- penicillin
- benzyl alcohol
- pharmaceutical composition
- aqueous solution
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930182555 Penicillin Natural products 0.000 title abstract 5
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title abstract 5
- 229940049954 penicillin Drugs 0.000 title abstract 5
- 238000002347 injection Methods 0.000 title abstract 2
- 239000007924 injection Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 abstract 6
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 235000019445 benzyl alcohol Nutrition 0.000 abstract 2
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 abstract 1
- 229960003022 amoxicillin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 239000011973 solid acid Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
CETTE COMPOSITION PHARMACEUTIQUE POUR INJECTION RENFERME UNE SOLUTION AQUEUSE STERILE D'UNE PENICILLINE OU D'UN SEL DE CELLE-CI, NOTAMMENT D'AMOXYCILLINE, ET DE 1 A 10 D'ALCOOL BENZYLIQUE, ET PEUT ETRE PRESENTEE SOUS FORME D'UN CONDITIONNEMENT FORME DE DEUX EMBALLAGES OU D'UNE SERINGUE EN DEUX PARTIES DANS LEQUEL UN EMBALLAGE OU UNE PARTIE RENFERME LA PENICILLINE OU SON SEL SOUS LA FORME D'UNE POUDRE SECHE, TANDIS QUE LE SECOND EMBALLAGE OU LA SECONDE PARTIE RENFERME UNE SOLUTION AQUEUSE D'ALCOOL BENZYLIQUE, DE TELLE SORTE QUE LE MELANGE DES CONTENUS DES DEUX EMBALLAGES OU PARTIES FOURNISSE UNE SOLUTION AQUEUSE DE LA PENICILLINE AVEC 1 A 10 D'ALCOOL BENZYLIQUE. LA PENICILLINE PEUT EGALEMENT SE PRESENTER SOUS LA FORME DE L'ACIDE LIBRE SOLIDE. LA SOLUTION AQUEUSE D'ALCOOL BENZYLIQUE RENFERME ALORS SENSIBLEMENT UN EQUIVALENT D'UN SEL ACIDE PHARMACEUTIQUEMENT ACCEPTABLE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7938767 | 1979-11-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2469179A1 true FR2469179A1 (fr) | 1981-05-22 |
FR2469179B1 FR2469179B1 (fr) | 1982-11-12 |
Family
ID=10509070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8014623A Granted FR2469179A1 (fr) | 1979-11-08 | 1980-07-01 | Composition pharmaceutique pour injection renfermant une penicilline |
Country Status (17)
Country | Link |
---|---|
US (1) | US4518606A (fr) |
EP (1) | EP0029668B1 (fr) |
JP (1) | JPS5686117A (fr) |
AT (1) | ATE5942T1 (fr) |
AU (1) | AU535184B2 (fr) |
CA (1) | CA1170571A (fr) |
DE (1) | DE3066309D1 (fr) |
DK (1) | DK475880A (fr) |
ES (1) | ES8202685A1 (fr) |
FR (1) | FR2469179A1 (fr) |
GR (1) | GR71928B (fr) |
IE (1) | IE50512B1 (fr) |
IL (1) | IL61406A (fr) |
MY (1) | MY8500960A (fr) |
NZ (1) | NZ195496A (fr) |
PT (1) | PT72026A (fr) |
ZA (1) | ZA806824B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59104319A (ja) * | 1982-12-06 | 1984-06-16 | Chugai Pharmaceut Co Ltd | 抗菌剤およびそのキツト |
FR2594334B1 (fr) * | 1986-02-20 | 1990-01-12 | Bristol Myers Co | Composition pharmaceutique injectable a base d'amoxicilline |
CN101474176B (zh) * | 2009-02-12 | 2010-08-18 | 海南本创医药科技有限公司 | 一种氟氯西林钠阿莫西林钠药物组合物及其制法 |
WO2016086223A1 (fr) | 2014-11-28 | 2016-06-02 | Markel Jay | Noyaux textiles non-tissés et moules pour fabriquer des parties intérieures et des parties extérieures sculpturales complexes de bouteilles en verre |
WO2016135075A1 (fr) * | 2015-02-23 | 2016-09-01 | Sandoz Ag | Composition retard de pénicilline pour injection intramusculaire |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1336M (fr) * | 1960-08-15 | 1962-05-28 | Warren Teed Products Company | Médicament anti-inflammatoire et hémostatique, son utilisation comme adjuvant au traitement des infections et compositions thérapeutiques constituées en vue d'une telle utilisation. |
FR2350844A1 (fr) * | 1976-05-13 | 1977-12-09 | Beecham Group Ltd | Composition pharmaceutique renfermant de l'amoxycilline |
GB1539510A (en) * | 1976-08-23 | 1979-01-31 | Beecham Group Ltd | Injectable compositions |
EP0008525A2 (fr) * | 1978-08-25 | 1980-03-05 | Beecham Group Plc | Compositions pharmaceutiques et procédé pour leur préparation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2829085A (en) * | 1955-06-21 | 1958-04-01 | Pfizer & Co C | Parenteral vehicle for therapeutic agents |
US2966442A (en) * | 1956-09-20 | 1960-12-27 | American Home Prod | Antibiotic compositions |
US3070507A (en) * | 1960-08-22 | 1962-12-25 | Pfizer & Co C | Novel corticoids from delta16-20-ketoalkenyl adducts |
GB1463563A (en) * | 1974-10-10 | 1977-02-02 | Beecham Group Ltd | Pharmaceutical compositions |
-
1980
- 1980-07-01 FR FR8014623A patent/FR2469179A1/fr active Granted
- 1980-11-03 EP EP80303909A patent/EP0029668B1/fr not_active Expired
- 1980-11-03 DE DE8080303909T patent/DE3066309D1/de not_active Expired
- 1980-11-03 AT AT80303909T patent/ATE5942T1/de not_active IP Right Cessation
- 1980-11-04 IL IL61406A patent/IL61406A/xx unknown
- 1980-11-05 ZA ZA00806824A patent/ZA806824B/xx unknown
- 1980-11-06 PT PT72026A patent/PT72026A/pt unknown
- 1980-11-07 AU AU64169/80A patent/AU535184B2/en not_active Ceased
- 1980-11-07 CA CA000364258A patent/CA1170571A/fr not_active Expired
- 1980-11-07 DK DK475880A patent/DK475880A/da not_active Application Discontinuation
- 1980-11-07 NZ NZ195496A patent/NZ195496A/en unknown
- 1980-11-07 ES ES496664A patent/ES8202685A1/es not_active Expired
- 1980-11-07 IE IE2314/80A patent/IE50512B1/en not_active IP Right Cessation
- 1980-11-07 GR GR63311A patent/GR71928B/el unknown
- 1980-11-08 JP JP15754880A patent/JPS5686117A/ja active Pending
-
1982
- 1982-07-09 US US06/396,711 patent/US4518606A/en not_active Expired - Fee Related
-
1985
- 1985-12-30 MY MY960/85A patent/MY8500960A/xx unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1336M (fr) * | 1960-08-15 | 1962-05-28 | Warren Teed Products Company | Médicament anti-inflammatoire et hémostatique, son utilisation comme adjuvant au traitement des infections et compositions thérapeutiques constituées en vue d'une telle utilisation. |
FR2350844A1 (fr) * | 1976-05-13 | 1977-12-09 | Beecham Group Ltd | Composition pharmaceutique renfermant de l'amoxycilline |
GB1539510A (en) * | 1976-08-23 | 1979-01-31 | Beecham Group Ltd | Injectable compositions |
EP0008525A2 (fr) * | 1978-08-25 | 1980-03-05 | Beecham Group Plc | Compositions pharmaceutiques et procédé pour leur préparation |
Also Published As
Publication number | Publication date |
---|---|
ATE5942T1 (de) | 1984-02-15 |
IE802314L (en) | 1981-05-08 |
ZA806824B (en) | 1981-11-25 |
NZ195496A (en) | 1984-12-14 |
EP0029668B1 (fr) | 1984-01-25 |
IE50512B1 (en) | 1986-04-30 |
ES496664A0 (es) | 1982-02-16 |
DK475880A (da) | 1981-05-09 |
EP0029668A1 (fr) | 1981-06-03 |
AU535184B2 (en) | 1984-03-08 |
FR2469179B1 (fr) | 1982-11-12 |
PT72026A (en) | 1980-12-01 |
US4518606A (en) | 1985-05-21 |
IL61406A0 (en) | 1980-12-31 |
AU6416980A (en) | 1981-05-14 |
CA1170571A (fr) | 1984-07-10 |
GR71928B (fr) | 1983-08-19 |
JPS5686117A (en) | 1981-07-13 |
DE3066309D1 (en) | 1984-03-01 |
ES8202685A1 (es) | 1982-02-16 |
IL61406A (en) | 1983-12-30 |
MY8500960A (en) | 1985-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |