DE3689097D1 - Synthetisches peptid und verfahren fuer dessen benutzung zum nachweis von antikoerpern zu htlv-iii, diagnose von aids und pre-aids-bedingungen und als impfstoffe. - Google Patents

Synthetisches peptid und verfahren fuer dessen benutzung zum nachweis von antikoerpern zu htlv-iii, diagnose von aids und pre-aids-bedingungen und als impfstoffe.

Info

Publication number
DE3689097D1
DE3689097D1 DE86303224T DE3689097T DE3689097D1 DE 3689097 D1 DE3689097 D1 DE 3689097D1 DE 86303224 T DE86303224 T DE 86303224T DE 3689097 T DE3689097 T DE 3689097T DE 3689097 D1 DE3689097 D1 DE 3689097D1
Authority
DE
Germany
Prior art keywords
aids
htlv
vaccine
diagnosis
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE86303224T
Other languages
English (en)
Other versions
DE3689097T2 (de
Inventor
James Jian Guang Wang
Chang Yi Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United Biomedical Inc
Original Assignee
United Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/847,102 external-priority patent/US4735896A/en
Application filed by United Biomedical Inc filed Critical United Biomedical Inc
Application granted granted Critical
Publication of DE3689097D1 publication Critical patent/DE3689097D1/de
Publication of DE3689097T2 publication Critical patent/DE3689097T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE86303224T 1985-09-11 1986-04-29 Synthetisches Peptid und Verfahren für dessen Benutzung zum Nachweis von Antikörpern zu HTLV-III, Diagnose von AIDS und PRE-AIDS-Bedingungen und als Impfstoffe. Expired - Fee Related DE3689097T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77464485A 1985-09-11 1985-09-11
US83756686A 1986-03-04 1986-03-04
US06/847,102 US4735896A (en) 1986-03-04 1986-04-02 Synthetic peptide and process of using same for the detection and diagnosis of AIDS and pre-AIDS conditions

Publications (2)

Publication Number Publication Date
DE3689097D1 true DE3689097D1 (de) 1993-11-04
DE3689097T2 DE3689097T2 (de) 1994-04-21

Family

ID=27419712

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198686303224T Pending DE214709T1 (de) 1985-09-11 1986-04-29 Synthetisches peptid und verfahren fuer dessen benutzung zum nachweis von antikoerpern zu htlv-iii, diagnose von aids und pre-aids-bedingungen und als impfstoffe.
DE86303224T Expired - Fee Related DE3689097T2 (de) 1985-09-11 1986-04-29 Synthetisches Peptid und Verfahren für dessen Benutzung zum Nachweis von Antikörpern zu HTLV-III, Diagnose von AIDS und PRE-AIDS-Bedingungen und als Impfstoffe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198686303224T Pending DE214709T1 (de) 1985-09-11 1986-04-29 Synthetisches peptid und verfahren fuer dessen benutzung zum nachweis von antikoerpern zu htlv-iii, diagnose von aids und pre-aids-bedingungen und als impfstoffe.

Country Status (9)

Country Link
EP (1) EP0214709B1 (de)
JP (1) JP2702911B2 (de)
AU (1) AU579467B2 (de)
DE (2) DE214709T1 (de)
DK (1) DK198086A (de)
ES (1) ES8801839A1 (de)
HK (1) HK95194A (de)
IL (1) IL78696A (de)
NO (1) NO176798C (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
DE3689941D1 (de) * 1985-10-24 1994-08-04 Southwest Found Biomed Res Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.
NZ218050A (en) * 1985-11-13 1989-05-29 Wistar Inst Test for the presence of htlv-1v
ATE98376T1 (de) * 1986-03-24 1993-12-15 Ortho Pharma Corp Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung.
US4879212A (en) * 1986-04-02 1989-11-07 United Biomedical Inc. Peptide composition and method for the detection of antibodies to HTLV-III
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DE3789633T2 (de) * 1986-05-27 1994-08-04 Hoffmann La Roche HTLV-III(LAV)Decke-Peptide.
US4943627A (en) * 1986-06-12 1990-07-24 Biogen, Inc. Peptides involved in the pathogenesis of HIV infection
US5017688A (en) * 1986-06-12 1991-05-21 Biogen, Inc. Peptides involved in the pathogenesis of HIV infection
US5087557A (en) * 1986-06-23 1992-02-11 Genetic Systems Corporation Human monoclonal antibody to lymphadenopathy-associated virus
DK169582B1 (da) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant
EP0276279A4 (de) * 1986-07-21 1990-01-08 Southwest Found Biomed Res Zubereitung, sowie verfahren zur immunisierung gegen virale aids- und arc-pathogene.
FR2610632B1 (fr) * 1987-02-11 1990-12-21 Pasteur Institut Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
ES2058259T5 (es) * 1987-03-25 2000-09-01 Genetic Systems Corp Antigenos sinteticos para la deteccion de enfermedad relacionada con sida causada por lav-2.
SE8701628D0 (sv) * 1987-04-16 1987-04-16 Erling Norrby Medel for analys mm
AU1711888A (en) * 1987-04-24 1988-12-02 Biogen, Inc. Immunotherapeutic methods and compositions
US4921787A (en) * 1987-05-01 1990-05-01 Cambridge Bioscience Corporation Detection of antibodies to human immunodeficiency virus by agglutination of antigen coated latex
US5854400A (en) * 1987-05-29 1998-12-29 Tanox, Inc. Monoclonal antibodies which neutralize HIV-1 infection
ATE122237T1 (de) * 1987-05-29 1995-05-15 Tanox Biosystems Inc Hiv-1 neutralisierende monoklonale antikörper.
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
SE8704185L (sv) * 1987-10-28 1989-04-29 Ferring Ab Nya peptider, artificiella antigener och immunoanalystestsatser
EP0323157A3 (de) * 1987-12-24 1990-07-25 The University Of Melbourne Antivirale Verbindungen und Methoden
SE8705197D0 (sv) * 1987-12-30 1987-12-30 Jonas Blomberg New peptides, two diagnostic methods using the peptides and a medicament based on the peptides
US5149623A (en) * 1988-02-09 1992-09-22 Virotest, Inc. Rapid, easy, and economical screening test for antibodies to human immunodeficiency virus
EP0330359A3 (de) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Zusammensetzung, verwendbar zur Diagnose und Behandlung von HIV-I-Infektion
AU608413B2 (en) * 1988-03-30 1991-03-28 Abbott Laboratories Mouse monoclonal antibody (5-21-3) to human immunodeficiency virus gp41 protein
JPH0292298A (ja) * 1988-09-30 1990-04-03 Olympus Optical Co Ltd Hiv構成蛋白に対するモノクローナル抗体
IL94558A0 (en) * 1989-06-06 1991-03-10 Merck & Co Inc Conjugate immunogen for aids and vaccine and pharmaceutical compositions containing it
IL95738A (en) * 1989-09-23 1996-11-14 Hoechst Ag Antibodies against the well-preserved amino acid sequences of insulin, a process for their preparation and use in immunoassay
US6248574B1 (en) 1989-12-13 2001-06-19 Avigdor Shaffermann Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides
DE69129207T2 (de) * 1990-01-16 1998-10-08 Orgenics Ltd Peptide, von Virus-HIV-Hüllen-Glycoproteinen abstammend, deren Verwendung zum Nachweis einer Infektion dieser Viren und für die Impfung gegen AIDS
FR2657017B1 (fr) * 1990-01-16 1995-08-18 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-1, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
ES2138784T3 (es) * 1990-12-14 2000-01-16 Innogenetics Nv Antigenos sinteticos para la deteccion de anticuerpos contra el virus de la hepatitis c.
US7119182B1 (en) 1991-02-19 2006-10-10 The Regents Of The University Of California Recombinant thrombin receptor and related pharmaceuticals
US5688768A (en) * 1991-02-19 1997-11-18 Cor Therapeutics, Inc. Recombinant thrombin receptor and related pharmaceuticals
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
CN103356636A (zh) 2004-05-23 2013-10-23 杰勒德·M·豪斯 Theramutein调节剂
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
CN102146116B (zh) * 2010-12-30 2013-02-13 桂林医学院 罗汉果甜苷v特异性抗血清的制备及检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI83662C (fi) * 1980-07-17 1991-08-12 Scripps Clinic Res Diagnostik antikropp och foerfarande foer dess framstaellning.
AU600224B2 (en) * 1984-09-19 1990-08-09 Regents Of The University Of California, The Retroviral polypeptides associated with human cellular transformation
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
FR2580177B2 (fr) * 1985-04-15 1989-06-02 Pasteur Institut Antigenes apparentes a la glycoproteine d'enveloppe du virus du sida, notamment precurseurs de cette glycoproteine, procedes d'obtention de ces antigenes et moyens mis en oeuvre dans ces procedes, applications de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic du sida ou des affections qui lui sont apparentees
EP0220273B2 (de) * 1985-04-29 2007-01-17 Bio-Rad Laboratories, Inc. Synthetische antigene zum nachweis von aids

Also Published As

Publication number Publication date
DK198086A (da) 1987-03-12
NO176798C (no) 1995-05-31
EP0214709A2 (de) 1987-03-18
NO861697L (no) 1987-03-12
EP0214709A3 (en) 1988-09-21
DK198086D0 (da) 1986-04-30
HK95194A (en) 1994-09-16
AU579467B2 (en) 1988-11-24
IL78696A0 (en) 1986-08-31
EP0214709B1 (de) 1993-09-29
JPS6261996A (ja) 1987-03-18
DE214709T1 (de) 1987-10-15
IL78696A (en) 1991-04-15
ES8801839A1 (es) 1988-02-16
AU5680386A (en) 1987-04-16
DE3689097T2 (de) 1994-04-21
ES554592A0 (es) 1988-02-16
JP2702911B2 (ja) 1998-01-26
NO176798B (no) 1995-02-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee