DE3688671D1 - Menschliches interferon-beta2a vektoren, die gene enthalten, die fuer das genannte interferon kodieren zellinien, die dieses produzieren und verwendung des genannten interferons als pharmazeutikum. - Google Patents

Menschliches interferon-beta2a vektoren, die gene enthalten, die fuer das genannte interferon kodieren zellinien, die dieses produzieren und verwendung des genannten interferons als pharmazeutikum.

Info

Publication number
DE3688671D1
DE3688671D1 DE8686114049T DE3688671T DE3688671D1 DE 3688671 D1 DE3688671 D1 DE 3688671D1 DE 8686114049 T DE8686114049 T DE 8686114049T DE 3688671 T DE3688671 T DE 3688671T DE 3688671 D1 DE3688671 D1 DE 3688671D1
Authority
DE
Germany
Prior art keywords
interferon
called
beta2a
encode
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686114049T
Other languages
English (en)
Other versions
DE3688671T3 (de
DE3688671T2 (de
Inventor
Michel Revel
Asher Zilberstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26321482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3688671(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL76714A external-priority patent/IL76714A0/xx
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of DE3688671D1 publication Critical patent/DE3688671D1/de
Publication of DE3688671T2 publication Critical patent/DE3688671T2/de
Publication of DE3688671T3 publication Critical patent/DE3688671T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3688671T 1985-10-14 1986-10-10 Menschliches Interferon-beta2A ; Vektoren, die Gene enthalten, die für das genannte Interferon kodieren; Zellinien, die dieses produzieren und Verwendung des genannten Interferons als Pharmazeutikum. Expired - Lifetime DE3688671T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL76714A IL76714A0 (en) 1985-10-14 1985-10-14 Recombined human interferon beta-2 and a method of producing same
US86088386A 1986-05-08 1986-05-08

Publications (3)

Publication Number Publication Date
DE3688671D1 true DE3688671D1 (de) 1993-08-12
DE3688671T2 DE3688671T2 (de) 1993-10-14
DE3688671T3 DE3688671T3 (de) 2001-05-03

Family

ID=26321482

Family Applications (4)

Application Number Title Priority Date Filing Date
DE3650790T Expired - Lifetime DE3650790T2 (de) 1985-10-14 1986-10-10 Menschlisches Interferon-Beta 2A zur Verwendung als Arzneimittel
DE3650715T Expired - Lifetime DE3650715T2 (de) 1985-10-14 1986-10-10 Verwendung von menschlichem Interferon-Beta 2A für die Herstellung von Medikamenten
DE198686114049T Pending DE220574T1 (de) 1985-10-14 1986-10-10 Menschliches interferon-beta2a und interferon-beta2b
DE3688671T Expired - Lifetime DE3688671T3 (de) 1985-10-14 1986-10-10 Menschliches Interferon-beta2A ; Vektoren, die Gene enthalten, die für das genannte Interferon kodieren; Zellinien, die dieses produzieren und Verwendung des genannten Interferons als Pharmazeutikum.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE3650790T Expired - Lifetime DE3650790T2 (de) 1985-10-14 1986-10-10 Menschlisches Interferon-Beta 2A zur Verwendung als Arzneimittel
DE3650715T Expired - Lifetime DE3650715T2 (de) 1985-10-14 1986-10-10 Verwendung von menschlichem Interferon-Beta 2A für die Herstellung von Medikamenten
DE198686114049T Pending DE220574T1 (de) 1985-10-14 1986-10-10 Menschliches interferon-beta2a und interferon-beta2b

Country Status (6)

Country Link
EP (4) EP0536520B1 (de)
AU (1) AU602872B2 (de)
CA (1) CA1341369C (de)
DE (4) DE3650790T2 (de)
ES (2) ES2131513T3 (de)
GR (2) GR3030150T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284237B1 (en) 1986-07-08 2001-09-04 Steven C. Clark Methods of treatment using IL-6
IE67035B1 (en) * 1986-07-08 1996-02-21 Genetics Inst Production and use of non-glycosylated IL-6
EP0585957A1 (de) * 1986-08-06 1994-03-09 Ajinomoto Co., Inc. Rekombinanter B-Zell-Differenzierungsfaktor
US4973478A (en) * 1987-07-20 1990-11-27 Allelix Biopharmaceuticals, Inc. Treating inflammation with hepatocyte stimulating factor interferon β2
NZ226799A (en) * 1987-11-06 1991-08-27 Oncogen Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor
IL85204A0 (en) * 1988-01-26 1988-07-31 Yeda Res & Dev Recombinant human interferon beta2,its preparation and pharmaceutical compositions comprising it
JPH0372429A (ja) * 1988-10-07 1991-03-27 Chugai Pharmaceut Co Ltd 血小板減少症の治療剤
US5641868A (en) * 1991-04-18 1997-06-24 Toray Industries, Inc. Interlekin-6 compositions, and a production process thereof
IT1254359B (it) * 1992-05-11 1995-09-14 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti il-6
US5902576A (en) * 1992-10-22 1999-05-11 Yeda Research And Development Co. Ltd. At Weizmann Institute Of Science Antitumor pharmaceutical composition comprising IL-6 transfected cells
US5338834A (en) * 1993-01-26 1994-08-16 Allelix Biopharmaceuticals Inc. Ultrapure human interleukin-6
IL147414A0 (en) 2001-12-31 2002-08-14 Yeda Res & Dev Ifnar2 mutants, their production and use
EP1542609B8 (de) * 2002-08-29 2013-02-20 CytoCure LLC Zusammensetzungen enthaltend Beta-Interferon zur Verwendung bei der Behandlung des Melanoms
EP1608400B1 (de) * 2003-03-28 2010-06-23 Faron Pharmaceuticals OY Erhöhung des adenosin-spiegels durch cytokin-induzierte expression von cd73
CN108004270B (zh) * 2017-11-24 2021-06-18 上海交通大学 利用双荧光素酶报告基因检测鸭IFN-β启动子活性的方法
CN112442504B (zh) * 2020-12-10 2023-01-24 电子科技大学 一种重组草鱼白介素-12活性蛋白的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
JPS60169424A (ja) * 1984-02-15 1985-09-02 Chuzo Kishimoto 新規ヒトｂ細胞分化因子，その製造法およびその使用法
JPS61246197A (ja) * 1985-04-24 1986-11-01 Ajinomoto Co Inc Ｄｎａ
IE67035B1 (en) * 1986-07-08 1996-02-21 Genetics Inst Production and use of non-glycosylated IL-6
EP0585957A1 (de) * 1986-08-06 1994-03-09 Ajinomoto Co., Inc. Rekombinanter B-Zell-Differenzierungsfaktor

Also Published As

Publication number Publication date
ES2058053T3 (es) 1994-11-01
DE220574T1 (de) 1987-11-26
EP0835661B1 (de) 2007-08-29
ES2058053T5 (es) 2000-11-01
DE3688671T3 (de) 2001-05-03
EP0220574B2 (de) 2000-04-12
AU602872B2 (en) 1990-11-01
AU6386786A (en) 1987-04-16
DE3650715D1 (de) 1999-04-08
EP0536520B1 (de) 1999-03-03
GR3033769T3 (en) 2000-10-31
EP0220574B1 (de) 1993-07-07
EP0835661A3 (de) 1998-05-20
EP0645452A1 (de) 1995-03-29
DE3650790T2 (de) 2008-01-24
DE3688671T2 (de) 1993-10-14
CA1341369C (en) 2002-06-18
GR3030150T3 (en) 1999-08-31
EP0536520A1 (de) 1993-04-14
DE3650790D1 (de) 2007-10-11
EP0220574A1 (de) 1987-05-06
ES2131513T3 (es) 1999-08-01
DE3650715T2 (de) 1999-06-24
EP0835661A2 (de) 1998-04-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings