IT9020072A0 - Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego - Google Patents

Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego

Info

Publication number
IT9020072A0
IT9020072A0 IT9020072A IT2007290A IT9020072A0 IT 9020072 A0 IT9020072 A0 IT 9020072A0 IT 9020072 A IT9020072 A IT 9020072A IT 2007290 A IT2007290 A IT 2007290A IT 9020072 A0 IT9020072 A0 IT 9020072A0
Authority
IT
Italy
Prior art keywords
episomial
preparation
recombinant dna
human cells
high expression
Prior art date
Application number
IT9020072A
Other languages
English (en)
Other versions
IT9020072A1 (it
IT1241123B (it
Inventor
Massimo Negrini
Paola Rimessi
Roberto Manservigi
Brodano Giuseppe Barbanti
Original Assignee
Consiglio Nazionale Ricerche
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale Ricerche, Ist Superiore Sanita filed Critical Consiglio Nazionale Ricerche
Priority to IT20072A priority Critical patent/IT1241123B/it
Publication of IT9020072A0 publication Critical patent/IT9020072A0/it
Priority to EP19910106111 priority patent/EP0452894A3/en
Publication of IT9020072A1 publication Critical patent/IT9020072A1/it
Application granted granted Critical
Publication of IT1241123B publication Critical patent/IT1241123B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT20072A 1990-04-19 1990-04-19 Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego IT1241123B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT20072A IT1241123B (it) 1990-04-19 1990-04-19 Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego
EP19910106111 EP0452894A3 (en) 1990-04-19 1991-04-17 Human cells for the high expression of genes inserted in episomal recombinant dna, their preparation and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20072A IT1241123B (it) 1990-04-19 1990-04-19 Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego

Publications (3)

Publication Number Publication Date
IT9020072A0 true IT9020072A0 (it) 1990-04-19
IT9020072A1 IT9020072A1 (it) 1991-10-19
IT1241123B IT1241123B (it) 1993-12-29

Family

ID=11163580

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20072A IT1241123B (it) 1990-04-19 1990-04-19 Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego

Country Status (2)

Country Link
EP (1) EP0452894A3 (it)
IT (1) IT1241123B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048729A (en) * 1987-05-01 2000-04-11 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
US6692737B1 (en) 1991-11-05 2004-02-17 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
US6054288A (en) * 1991-11-05 2000-04-25 Transkaryotic Therapies, Inc. In vivo protein production and delivery system for gene therapy
US6270989B1 (en) 1991-11-05 2001-08-07 Transkaryotic Therapies, Inc. Protein production and delivery
US5968502A (en) * 1991-11-05 1999-10-19 Transkaryotic Therapies, Inc. Protein production and protein delivery
PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6063630A (en) * 1991-11-05 2000-05-16 Transkaryotic Therapies, Inc. Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
US6531124B1 (en) 1992-07-10 2003-03-11 Transkaryotic Therapies, Inc. In vivo production and delivery of insulinotropin for gene therapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738922A (en) * 1984-05-25 1988-04-19 Dana Farber Cancer Institute Trans-acting transcriptional factors
EP0291893A1 (en) * 1987-05-19 1988-11-23 The Du Pont Merck Pharmaceutical Company Stable human cell lines expressing an indicator gene product under virus-specific genetic controls
US5024939A (en) * 1987-07-09 1991-06-18 Genentech, Inc. Transient expression system for producing recombinant protein

Also Published As

Publication number Publication date
EP0452894A3 (en) 1992-03-18
IT9020072A1 (it) 1991-10-19
IT1241123B (it) 1993-12-29
EP0452894A2 (en) 1991-10-23

Similar Documents

Publication Publication Date Title
IL74909A (en) Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
FR2647808B1 (fr) Poxvirus recombinant et vaccin contre le virus de l'herpes contenant ce poxvirus
NZ289028A (en) Use of antisense nucleic acids in the treatment of skin disease
EP0257444A3 (en) Tercopolymers, their use in hair treatment compositions and hair treatment compositions containing them
IT8520110A0 (it) Elettrodo, apparecchiatura e defibrillazione per l'impianto in corpi umani o animali.
FI951600L (fi) Terapeuttinen HIV:n vastainen oligonukleotidi ja lääkeaine
ITRM940328A0 (it) "uso di prodotti contenenti magnesio nella terapia e nella profilassi di malattie neoplastiche e di malattie di tipo autoimmunitario".-
IT8948564A0 (it) Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote
IT1217121B (it) Eteri di poligliceroli e loro impiego in composizioni cosmetiche e farmaceutiche
IT9020072A0 (it) Cellule umane per l'elevata espressione di geni inseriti in dna ricombinanti episomiali,loro preparazione e loro impiego
IT8468281A1 (it) Proglumide e composizioni farmaceutiche che la contengono per l'impiego nella terapia di affezioni neoplastiche.
FR2632646B1 (fr) Derives de la carboxymethylcellulose contenant de l'azote, leur preparation et leur utilisation dans des preparations cosmetiques
IT8883551A0 (it) Procedimento per l'estrazione e la purificazione di dna
FR2613118B1 (fr) Perovskites oxyazotees conductrices, leur preparation et leur utilisation notamment comme materiau d'electrode
FI924475A7 (fi) Trinitrobentseenien tai karmiinihapon käyttö syövän ja virusperäisten sairauksien hoidossa
FI893683L (fi) Ihmisen papilloomavirus tyyppi 57, sen eristetty DNA ja näiden käyttö
DK0600893T3 (da) Genekspression i Bacilli
GB2203645B (en) Improvements in the treatment of hair
GB2293604B (en) Dermal fibroblast cells containing muscle-specific DNA and the use of dermal fibroblast cells in the treatment of muscular disorders
IT1186740B (it) Diacilossi-1,8 acil-10 antroni,loro procedimento di preparazione e loro impiego in medicina umana od in medicina veterinaria ed in cosmetica
ITRM910474A0 (it) Vettori plasmidici per l'espressione di geni in piante.
IL97801A0 (en) Oligonucleotides,methods for in vitro tissue cell culture using the same and cosmetic compositions containing the same
CS92092A3 (en) Substituted 2',3'-dideoxy-5-trifluoromethyl uridines, process forpreparing thereof and their use in medicaments
IL97110A0 (en) Benzylphosphonic acid derivatives,compositions containing them and their use in treating viral diseases
FR2542744B2 (fr) 3',5'-diarabinosides, leur preparation et leur application en therapeutique

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960429