|
US6090406A
(en)
*
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US5916588A
(en)
*
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
US4761287A
(en)
*
|
1984-05-03 |
1988-08-02 |
Technology Unlimited, Inc. |
Diabetes control by serotonin
|
|
US4767615A
(en)
*
|
1984-05-03 |
1988-08-30 |
Technology Unlimited, Inc. |
Dental therapy by vesicle delivery
|
|
US4863896A
(en)
*
|
1984-05-03 |
1989-09-05 |
Technology Unlimited, Inc. |
Diabetic control by combined insulin forms
|
|
US4740375A
(en)
*
|
1985-02-25 |
1988-04-26 |
Technology Unlimited, Inc. |
Gelcores
|
|
US4828982A
(en)
*
|
1985-05-28 |
1989-05-09 |
Becton, Dickinson & Company |
Vesticles and use thereof in an enzyme assay
|
|
NZ217821A
(en)
*
|
1985-10-10 |
1989-07-27 |
Biotech Australia Pty Ltd |
Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
|
|
US5023086A
(en)
*
|
1987-03-13 |
1991-06-11 |
Micro-Pak, Inc. |
Encapsulated ionophore growth factors
|
|
US5000960A
(en)
*
|
1987-03-13 |
1991-03-19 |
Micro-Pak, Inc. |
Protein coupling to lipid vesicles
|
|
PH26549A
(en)
*
|
1987-04-03 |
1992-08-19 |
Meito Sangyo Kk |
Mannobiose derivatives
|
|
US5807832A
(en)
*
|
1987-06-09 |
1998-09-15 |
Biotech Australia Pty Limited |
Oral delivery of biologically active substances bound to vitamin B12
|
|
WO1989005151A1
(en)
*
|
1987-12-04 |
1989-06-15 |
The Liposome Company, Inc. |
High integrity liposomes and method of preration and use
|
|
DE3886775T2
(de)
|
1988-08-22 |
1994-04-14 |
Technology Unlimited Inc |
Zahnbehandlung durch freisetzung von vesikeln.
|
|
US4942036A
(en)
*
|
1988-08-25 |
1990-07-17 |
Blair Geho W |
Therapy by vesicle delivery to the hydroxyapatite of bone
|
|
US5026558A
(en)
*
|
1989-01-31 |
1991-06-25 |
University Of Southern California |
Targeting drugs to hepatocytes in the liver
|
|
US5104661A
(en)
*
|
1989-08-14 |
1992-04-14 |
Technology Unlimited, Inc. |
Reverse loading of liposomes
|
|
US20020150539A1
(en)
|
1989-12-22 |
2002-10-17 |
Unger Evan C. |
Ultrasound imaging and treatment
|
|
US5733572A
(en)
*
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
US5305757A
(en)
*
|
1989-12-22 |
1994-04-26 |
Unger Evan C |
Gas filled liposomes and their use as ultrasonic contrast agents
|
|
US6001335A
(en)
*
|
1989-12-22 |
1999-12-14 |
Imarx Pharmaceutical Corp. |
Contrasting agents for ultrasonic imaging and methods for preparing the same
|
|
US6088613A
(en)
*
|
1989-12-22 |
2000-07-11 |
Imarx Pharmaceutical Corp. |
Method of magnetic resonance focused surgical and therapeutic ultrasound
|
|
US5230882A
(en)
*
|
1989-12-22 |
1993-07-27 |
Unger Evan C |
Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
|
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
|
US5585112A
(en)
*
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
US5123414A
(en)
*
|
1989-12-22 |
1992-06-23 |
Unger Evan C |
Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
|
|
US5776429A
(en)
*
|
1989-12-22 |
1998-07-07 |
Imarx Pharmaceutical Corp. |
Method of preparing gas-filled microspheres using a lyophilized lipids
|
|
US5656211A
(en)
*
|
1989-12-22 |
1997-08-12 |
Imarx Pharmaceutical Corp. |
Apparatus and method for making gas-filled vesicles of optimal size
|
|
US5334381A
(en)
*
|
1989-12-22 |
1994-08-02 |
Unger Evan C |
Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
|
|
US5773024A
(en)
*
|
1989-12-22 |
1998-06-30 |
Imarx Pharmaceutical Corp. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
|
US5088499A
(en)
*
|
1989-12-22 |
1992-02-18 |
Unger Evan C |
Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
|
|
US5922304A
(en)
|
1989-12-22 |
1999-07-13 |
Imarx Pharmaceutical Corp. |
Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
|
|
US6146657A
(en)
*
|
1989-12-22 |
2000-11-14 |
Imarx Pharmaceutical Corp. |
Gas-filled lipid spheres for use in diagnostic and therapeutic applications
|
|
US5469854A
(en)
*
|
1989-12-22 |
1995-11-28 |
Imarx Pharmaceutical Corp. |
Methods of preparing gas-filled liposomes
|
|
US6551576B1
(en)
|
1989-12-22 |
2003-04-22 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
|
US5705187A
(en)
*
|
1989-12-22 |
1998-01-06 |
Imarx Pharmaceutical Corp. |
Compositions of lipids and stabilizing materials
|
|
US5352435A
(en)
*
|
1989-12-22 |
1994-10-04 |
Unger Evan C |
Ionophore containing liposomes for ultrasound imaging
|
|
US5580575A
(en)
*
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
|
US5213810A
(en)
*
|
1990-03-30 |
1993-05-25 |
American Cyanamid Company |
Stable compositions for parenteral administration and method of making same
|
|
US5190822A
(en)
*
|
1990-04-20 |
1993-03-02 |
Fuji Photo Film Co., Ltd. |
Surface-modifiable liposome and process for producing surface-modified liposome
|
|
ZA922425B
(en)
*
|
1991-04-02 |
1993-02-24 |
Biotech Australia Pty Ltd |
Oral delivery systems for microparticles
|
|
AU707085B2
(en)
*
|
1991-04-02 |
1999-07-01 |
Access Pharmaceuticals Australia Pty Limited |
Oral delivery systems for microparticles
|
|
US5874062A
(en)
*
|
1991-04-05 |
1999-02-23 |
Imarx Pharmaceutical Corp. |
Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
|
|
US5205290A
(en)
|
1991-04-05 |
1993-04-27 |
Unger Evan C |
Low density microspheres and their use as contrast agents for computed tomography
|
|
CA2070061C
(en)
*
|
1991-06-07 |
2004-02-10 |
Shigeyuki Takama |
Physiologically active polypeptide-containing pharmaceutical composition
|
|
US7083572B2
(en)
|
1993-11-30 |
2006-08-01 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Therapeutic delivery systems
|
|
US5534499A
(en)
*
|
1994-05-19 |
1996-07-09 |
The University Of British Columbia |
Lipophilic drug derivatives for use in liposomes
|
|
US5736121A
(en)
*
|
1994-05-23 |
1998-04-07 |
Imarx Pharmaceutical Corp. |
Stabilized homogenous suspensions as computed tomography contrast agents
|
|
GB9420390D0
(en)
*
|
1994-10-10 |
1994-11-23 |
Nycomed Salutar Inc |
Liposomal agents
|
|
US6743779B1
(en)
|
1994-11-29 |
2004-06-01 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
|
US5830430A
(en)
*
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
|
US5997898A
(en)
*
|
1995-06-06 |
1999-12-07 |
Imarx Pharmaceutical Corp. |
Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
|
|
US6139819A
(en)
*
|
1995-06-07 |
2000-10-31 |
Imarx Pharmaceutical Corp. |
Targeted contrast agents for diagnostic and therapeutic use
|
|
US6231834B1
(en)
|
1995-06-07 |
2001-05-15 |
Imarx Pharmaceutical Corp. |
Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
|
|
US6521211B1
(en)
|
1995-06-07 |
2003-02-18 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Methods of imaging and treatment with targeted compositions
|
|
US6033645A
(en)
*
|
1996-06-19 |
2000-03-07 |
Unger; Evan C. |
Methods for diagnostic imaging by regulating the administration rate of a contrast agent
|
|
CA2252617A1
(en)
|
1996-05-01 |
1997-11-06 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
|
GB9612264D0
(en)
*
|
1996-06-12 |
1996-08-14 |
Samsoondar James |
Quality control material for monitoring calibration of instruments designed to measure serum and plasma specimen integrity
|
|
US7157282B2
(en)
*
|
1996-06-12 |
2007-01-02 |
Spectromedical Inc. |
Quality control material for reagentless measurement of analytes
|
|
US6828152B2
(en)
*
|
1996-06-12 |
2004-12-07 |
Spectromedical Inc. |
Quality control material for reagentless measurement of analytes
|
|
US6414139B1
(en)
|
1996-09-03 |
2002-07-02 |
Imarx Therapeutics, Inc. |
Silicon amphiphilic compounds and the use thereof
|
|
US5846517A
(en)
*
|
1996-09-11 |
1998-12-08 |
Imarx Pharmaceutical Corp. |
Methods for diagnostic imaging using a renal contrast agent and a vasodilator
|
|
DE69718519T2
(de)
*
|
1996-09-11 |
2003-11-06 |
Imarx Pharmaceutical Corp., Tucson |
Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
US6143276A
(en)
*
|
1997-03-21 |
2000-11-07 |
Imarx Pharmaceutical Corp. |
Methods for delivering bioactive agents to regions of elevated temperatures
|
|
US6537246B1
(en)
|
1997-06-18 |
2003-03-25 |
Imarx Therapeutics, Inc. |
Oxygen delivery agents and uses for the same
|
|
US6090800A
(en)
*
|
1997-05-06 |
2000-07-18 |
Imarx Pharmaceutical Corp. |
Lipid soluble steroid prodrugs
|
|
US7452551B1
(en)
|
2000-10-30 |
2008-11-18 |
Imarx Therapeutics, Inc. |
Targeted compositions for diagnostic and therapeutic use
|
|
US6416740B1
(en)
|
1997-05-13 |
2002-07-09 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Acoustically active drug delivery systems
|
|
EP1005327A1
(en)
*
|
1997-07-02 |
2000-06-07 |
Sdg, Inc. |
Targeted liposomal constructs for diagnostic and therapeutic uses
|
|
US6548047B1
(en)
|
1997-09-15 |
2003-04-15 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Thermal preactivation of gaseous precursor filled compositions
|
|
GB9721901D0
(en)
|
1997-10-16 |
1997-12-17 |
Univ Manchester |
Particles
|
|
EP1903114A3
(en)
|
1997-12-01 |
2008-07-23 |
Neose Technologies, Inc. |
Enzymatic synthesis of gangliosides
|
|
US6123923A
(en)
*
|
1997-12-18 |
2000-09-26 |
Imarx Pharmaceutical Corp. |
Optoacoustic contrast agents and methods for their use
|
|
US6320017B1
(en)
*
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
US20010003580A1
(en)
|
1998-01-14 |
2001-06-14 |
Poh K. Hui |
Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
|
|
US7169410B1
(en)
*
|
1998-05-19 |
2007-01-30 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
US7871641B2
(en)
*
|
1998-05-19 |
2011-01-18 |
Sdg, Inc. |
Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal
|
|
AU3999699A
(en)
*
|
1998-05-19 |
1999-12-06 |
Sdg, Inc. |
Targeted liposomal drug delivery system
|
|
WO2000059473A1
(en)
|
1999-04-01 |
2000-10-12 |
Inex Pharmaceuticals Corp. |
Compositions and methods for treating lymphoma
|
|
US6723338B1
(en)
*
|
1999-04-01 |
2004-04-20 |
Inex Pharmaceuticals Corporation |
Compositions and methods for treating lymphoma
|
|
US7244450B2
(en)
*
|
1999-04-01 |
2007-07-17 |
Inex Pharmaceuticals Corporation |
Compositions and methods for treating lymphoma
|
|
US7311924B2
(en)
|
1999-04-01 |
2007-12-25 |
Hana Biosciences, Inc. |
Compositions and methods for treating cancer
|
|
AU5269800A
(en)
|
1999-05-14 |
2000-12-05 |
Arbor Vita Corporation |
Molecular interactions in allergy cells
|
|
DE60045931D1
(de)
|
1999-07-07 |
2011-06-16 |
Zymogenetics Inc |
Menschliches Rezeptor für Zytokine
|
|
US7449339B2
(en)
*
|
1999-11-23 |
2008-11-11 |
Nir Diagnostics Inc. |
Spectroscopic method and apparatus for total hemoglobin measurement
|
|
US6949384B2
(en)
*
|
2001-12-21 |
2005-09-27 |
Spectromedical Inc. |
Method for monitoring degradation of Hb-based blood substitutes
|
|
US20050037505A1
(en)
*
|
2000-05-11 |
2005-02-17 |
James Samsoondar |
Spectroscopic method and apparatus for analyte measurement
|
|
DE60143192D1
(de)
|
2000-02-08 |
2010-11-18 |
Sangamo Biosciences Inc |
Zellen zur entdeckung von medikamenten
|
|
EA010594B1
(ru)
|
2001-05-24 |
2008-10-30 |
Займодженетикс, Инк. |
Слитые белки taci-иммуноглобулина
|
|
US8735153B2
(en)
*
|
2001-09-24 |
2014-05-27 |
Sangamo Biosciences, Inc. |
Modulation of stem cells using zinc finger proteins
|
|
EP2042196B1
(en)
|
2001-10-10 |
2016-07-13 |
ratiopharm GmbH |
Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF)
|
|
ES2377188T3
(es)
|
2002-01-18 |
2012-03-23 |
Zymogenetics, Inc. |
Nuevo ligando de citocina ZCYTOR17
|
|
ES2382800T3
(es)
|
2002-01-18 |
2012-06-13 |
Zymogenetics, Inc. |
Multímeros Zcytor17 receptores de citocinas
|
|
JP2005535575A
(ja)
*
|
2002-04-11 |
2005-11-24 |
ザイモジェネティクス インコーポレイティッド |
卵巣癌を治療するためのインターロイキン−24の使用法
|
|
US7273620B1
(en)
|
2002-05-20 |
2007-09-25 |
University Of British Columbia |
Triggered release of liposomal drugs following mixing of cationic and anionic liposomes
|
|
JP2006523211A
(ja)
|
2003-03-14 |
2006-10-12 |
ネオス テクノロジーズ インコーポレイテッド |
分岐水溶性ポリマーとその複合物
|
|
NZ542586A
(en)
|
2003-04-09 |
2009-11-27 |
Biogenerix Ag |
Method of forming a covalent conjugate between a G-CSF peptide and PEG
|
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
|
JP4555292B2
(ja)
|
2003-08-08 |
2010-09-29 |
サンガモ バイオサイエンシズ インコーポレイテッド |
標的化された切断及び組換えの方法及び組成物
|
|
US7407776B2
(en)
|
2003-09-19 |
2008-08-05 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for regulation of gene expression
|
|
US20080119412A1
(en)
|
2003-12-23 |
2008-05-22 |
Nono Inc. |
Polypeptides for Modulating Binding of Trp Channel Proteins and Trp- Associated Proteins
|
|
JP4903689B2
(ja)
*
|
2004-04-08 |
2012-03-28 |
サンガモ バイオサイエンシズ インコーポレイテッド |
神経障害および神経変性症状を治療するための方法と組成物
|
|
EP1732945B1
(en)
*
|
2004-04-08 |
2014-12-24 |
Sangamo BioSciences, Inc. |
Methods and compositions for modulating cardiac contractility
|
|
ATE450251T1
(de)
*
|
2004-05-17 |
2009-12-15 |
Tekmira Pharmaceuticals Corp |
Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung
|
|
EP2292274A1
(en)
|
2004-09-16 |
2011-03-09 |
Sangamo BioSciences, Inc. |
Compositions and methods for protein production
|
|
KR100695742B1
(ko)
|
2004-11-30 |
2007-03-19 |
한국원자력연구소 |
마이크로파 조사를 이용한 disida 및 그 유도체 또는 메브로페닌의 제조 방법
|
|
US9029331B2
(en)
|
2005-01-10 |
2015-05-12 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
|
EP2192132A3
(en)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-IL-20, anti-IL22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation
|
|
EP1869075B1
(en)
*
|
2005-02-28 |
2012-04-11 |
Sangamo BioSciences, Inc. |
Anti-angiogenic methods and compositions
|
|
EP1871795A4
(en)
|
2005-04-08 |
2010-03-31 |
Biogenerix Ag |
COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE
|
|
BRPI0611069A2
(pt)
|
2005-05-06 |
2010-11-09 |
Zymogenetics Inc |
anticorpo monoclonal, anticorpo humanizado, fragmento de anticorpo, uso de um antagonista, e, hibridoma
|
|
JP2008544746A
(ja)
|
2005-05-12 |
2008-12-11 |
ザイモジェネティクス, インコーポレイテッド |
免疫応答を調節するための組成物および方法
|
|
DE102005023442A1
(de)
*
|
2005-05-20 |
2006-11-30 |
BSH Bosch und Siemens Hausgeräte GmbH |
Haushaltgerät zur Pflege von Wäschestücken insbesondere Wäschetrockner
|
|
PL1883394T3
(pl)
*
|
2005-05-23 |
2018-09-28 |
Sdg, Inc. |
Konstrukt lipidowy do dostarczania insuliny ssakowi
|
|
AU2012247063B2
(en)
*
|
2005-05-23 |
2015-07-30 |
Sdg, Inc. |
Lipid construct for delivery of insulin to a mammal
|
|
CN101237855A
(zh)
*
|
2005-05-23 |
2008-08-06 |
Sdg公司 |
将干扰素输送到哺乳动物的脂构建体
|
|
AU2006249479A1
(en)
*
|
2005-05-23 |
2006-11-30 |
Sdg, Inc. |
Lipid construct for delivery of interferon to a mammal
|
|
US20110135725A1
(en)
*
|
2005-05-23 |
2011-06-09 |
Sdg, Inc. |
Lipid Construct for Delivery of Insulin to a Mammal
|
|
US20070218117A1
(en)
*
|
2006-03-20 |
2007-09-20 |
Sdg, Inc. |
Supra molecular construct for delivery of interferon to a mammal
|
|
WO2007014275A2
(en)
|
2005-07-26 |
2007-02-01 |
Sangamo Biosciences, Inc. |
Targeted integration and expression of exogenous nucleic acid sequences
|
|
CN101360422B
(zh)
|
2005-11-23 |
2013-10-23 |
得克萨斯大学体系董事会 |
致癌Ras特异性细胞毒化合物及其使用方法
|
|
EP2805971A1
(en)
|
2005-11-28 |
2014-11-26 |
ZymoGenetics, Inc. |
IL-21 antagonists
|
|
WO2007106769A2
(en)
|
2006-03-10 |
2007-09-20 |
Zymogenetics, Inc. |
Antibodies that bind both il-17a and il-17f and methods of using the same
|
|
BRPI0717505B8
(pt)
|
2006-10-04 |
2021-05-25 |
Novo Nordisk As |
conjugado de peptídeo e formulação farmacêutica
|
|
HUE041957T2
(hu)
|
2006-12-01 |
2019-06-28 |
Novartis Ag |
Anti-P-szelektin antitestek és eljárások azok alkalmazására gyulladásos betegségek kezelésére
|
|
KR100700419B1
(ko)
|
2006-12-22 |
2007-03-28 |
한국원자력연구소 |
마이크로파 조사를 이용한 disida 및 그 유도체 또는메브로페닌의 제조 방법
|
|
ES2465223T3
(es)
|
2007-04-27 |
2014-06-05 |
Zymogenetics, Inc. |
Antagonistas de IL-17A, IL-17F e IL-23P19 y procedimientos de uso
|
|
US8846053B2
(en)
|
2008-09-26 |
2014-09-30 |
Sdg, Inc. |
Orally bioavailable lipid-based constructs
|
|
US20100080773A1
(en)
|
2008-09-26 |
2010-04-01 |
Sdg, Inc. |
Orally Bioavailable Lipid-Based Constructs
|
|
US8962015B2
(en)
|
2007-09-28 |
2015-02-24 |
Sdg, Inc. |
Orally bioavailable lipid-based constructs
|
|
US9145453B2
(en)
*
|
2007-09-28 |
2015-09-29 |
Sdg, Inc. |
Orally bioavailable lipid-based constructs
|
|
JP5749494B2
(ja)
|
2008-01-02 |
2015-07-15 |
テクミラ ファーマシューティカルズ コーポレイション |
核酸の送達のための改善された組成物および方法
|
|
JP5785490B2
(ja)
|
2008-04-02 |
2015-09-30 |
マクロジェニクス,インコーポレーテッド |
Bcr複合体特異的抗体およびその使用方法
|
|
HUE029925T2
(en)
|
2008-04-02 |
2017-04-28 |
Macrogenics Inc |
HER2 / neu-specific antibodies and methods using them
|
|
US20090281054A1
(en)
*
|
2008-05-06 |
2009-11-12 |
Venkata Reddy |
Compositions and methods comprising capuramycin analogues
|
|
CA2726845C
(en)
|
2008-06-04 |
2017-09-26 |
Macrogenics, Inc. |
Antibodies with altered binding to fcrn and methods of using same
|
|
JP5777519B2
(ja)
|
2008-10-09 |
2015-09-09 |
テクミラ ファーマシューティカルズ コーポレイション |
改良されたアミノ脂質および核酸の送達方法
|
|
EP4241767B1
(en)
|
2008-11-10 |
2024-10-23 |
Arbutus Biopharma Corporation |
Novel lipids and compositions for the delivery of therapeutics
|
|
BRPI1007457A2
(pt)
|
2009-01-28 |
2015-08-25 |
Smartcells Inc |
Conjungado, formulação de liberação prolongada, e, sistema de distribuição de bomba.
|
|
JP2012516342A
(ja)
|
2009-01-28 |
2012-07-19 |
スマートセルズ・インコーポレイテツド |
結晶性インスリン複合体
|
|
CA2750223A1
(en)
|
2009-01-28 |
2010-08-05 |
Smartcells, Inc. |
Exogenously triggered controlled release materials and uses thereof
|
|
WO2010088286A1
(en)
|
2009-01-28 |
2010-08-05 |
Smartcells, Inc. |
Synthetic conjugates and uses thereof
|
|
US20120101148A1
(en)
|
2009-01-29 |
2012-04-26 |
Alnylam Pharmaceuticals, Inc. |
lipid formulation
|
|
AU2010223967B2
(en)
|
2009-03-12 |
2015-07-30 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of Eg5 and VEGF genes
|
|
EP2408470A4
(en)
|
2009-03-20 |
2012-08-29 |
Smartcells Inc |
SOLUBLE NONDEPOT INSULIN CONJUGATE AND ITS USE
|
|
CA2754950A1
(en)
|
2009-03-20 |
2010-09-23 |
Smartcells, Inc. |
Terminally-functionalized conjugates and uses thereof
|
|
SG176553A1
(en)
|
2009-05-05 |
2012-01-30 |
Muthiah Manoharan |
Lipid compositions
|
|
CA2760706C
(en)
|
2009-05-05 |
2019-08-06 |
Alnylam Pharmaceuticals, Inc. |
Methods of delivering oligonucleotides to immune cells
|
|
TR201811076T4
(tr)
|
2009-06-10 |
2018-08-27 |
Arbutus Biopharma Corp |
Geliştirilmiş lipit formulasyonu.
|
|
JP2012533587A
(ja)
|
2009-07-22 |
2012-12-27 |
セニックス バイオサイエンス ゲーエムベーハー |
自然に存在する細胞内輸送経路を介して化合物を送達するための送達システム及びコンジュゲート
|
|
EP2464336A4
(en)
|
2009-08-14 |
2013-11-20 |
Alnylam Pharmaceuticals Inc |
COMPOSITIONS FORMULATED IN LIPIDS AND METHODS OF INHIBITING THE EXPRESSION OF EBOLA VIRUS GENE
|
|
JP5888728B2
(ja)
|
2009-11-05 |
2016-03-22 |
国立大学法人大阪大学 |
自己免疫疾患又はアレルギー治療剤とそのスクリーニング方法
|
|
WO2011071860A2
(en)
|
2009-12-07 |
2011-06-16 |
Alnylam Pharmaceuticals, Inc. |
Compositions for nucleic acid delivery
|
|
EP3494963A1
(en)
|
2009-12-18 |
2019-06-12 |
The University of British Columbia |
Methods and compositions for delivery of nucleic acids
|
|
AU2011206761A1
(en)
|
2010-01-13 |
2012-07-12 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Anti - infective pyrido (1,2 -a) pyrimidines
|
|
US9556248B2
(en)
|
2010-03-19 |
2017-01-31 |
The Board Of Trustees Of The Leland Stanford Junior University |
Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists
|
|
US20130156845A1
(en)
|
2010-04-29 |
2013-06-20 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
|
CA2800401C
(en)
|
2010-06-03 |
2020-09-15 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
|
US9068013B2
(en)
|
2010-07-28 |
2015-06-30 |
Smart Cells, Inc. |
Recombinant lectins, binding-site modified lectins and uses thereof
|
|
US9074015B2
(en)
|
2010-07-28 |
2015-07-07 |
Smartcells, Inc. |
Recombinantly expressed insulin polypeptides and uses thereof
|
|
EP2598170A4
(en)
|
2010-07-28 |
2016-07-06 |
Smartcells Inc |
MEDICINAL LIGANDEN CONJUGATES, THEIR SYNTHESIS AND INTERMEDIATE PRODUCTS THEREOF
|
|
WO2012016188A2
(en)
|
2010-07-30 |
2012-02-02 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for delivery of active agents
|
|
US20130323269A1
(en)
|
2010-07-30 |
2013-12-05 |
Muthiah Manoharan |
Methods and compositions for delivery of active agents
|
|
US8916387B2
(en)
|
2010-10-28 |
2014-12-23 |
Jonas Nilsson |
Diagnosis and treatment of Alzheimer's disease
|
|
CN110123830A
(zh)
|
2010-11-09 |
2019-08-16 |
阿尔尼拉姆医药品有限公司 |
用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法
|
|
US9211346B2
(en)
|
2010-12-13 |
2015-12-15 |
Trustees Of Dartmouth College |
Carrier-linked magnetic nanoparticle drug delivery composition and method of use
|
|
JP5902197B2
(ja)
|
2011-01-11 |
2016-04-13 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
Peg化脂質および薬剤送達のためのそれらの使用
|
|
US20140274812A1
(en)
|
2011-07-15 |
2014-09-18 |
The General Hospital Corporation |
Methods of Transcription Activator Like Effector Assembly
|
|
EP2760477B1
(en)
|
2011-09-27 |
2018-08-08 |
Alnylam Pharmaceuticals, Inc. |
Di-aliphatic substituted pegylated lipids
|
|
ES2711554T3
(es)
|
2012-05-22 |
2019-05-06 |
Bristol Myers Squibb Co |
Anticuerpos biespecíficos contra IL-17A/F IL-23 y sus usos
|
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
|
EP2906602B1
(en)
|
2012-10-12 |
2019-01-16 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
|
KR102310697B1
(ko)
|
2012-11-20 |
2021-10-12 |
스펙트럼 파마슈티컬즈 인크 |
치료적 사용을 위한 리포솜 캡슐화 빈크리스틴을 제조하기 위한 개선된 방법
|
|
CA2900338C
(en)
|
2013-02-07 |
2024-11-05 |
The General Hospital Corporation |
TRANSCRIPTIONAL ACTIVATORS TALE
|
|
US10760064B2
(en)
|
2013-03-15 |
2020-09-01 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
US10378027B2
(en)
|
2013-03-15 |
2019-08-13 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
WO2014204578A1
(en)
|
2013-06-21 |
2014-12-24 |
The General Hospital Corporation |
Using rna-guided foki nucleases (rfns) to increase specificity for rna-guided genome editing
|
|
AU2014329567B2
(en)
|
2013-10-04 |
2019-07-25 |
Merck Sharp & Dohme Corp. |
Glucose-responsive insulin conjugates
|
|
US10300073B2
(en)
|
2014-10-14 |
2019-05-28 |
The Regents Of The University Of California |
Use of CDK9 and BRD4 inhibitors to inhibit inflammation
|
|
CN114642735A
(zh)
|
2015-01-21 |
2022-06-21 |
菲泽尔克斯公司 |
用于将治疗剂和诊断剂递送到细胞中的方法、组合物和系统
|
|
WO2016180986A1
(en)
|
2015-05-14 |
2016-11-17 |
Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (Cnic) |
Mirna compositions for the treatment of mature b-cell neoplasms
|
|
TWI678213B
(zh)
|
2015-07-22 |
2019-12-01 |
美商史倍壯製藥公司 |
用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
|
|
US9512446B1
(en)
|
2015-08-28 |
2016-12-06 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
US9926546B2
(en)
|
2015-08-28 |
2018-03-27 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
|
US10519442B2
(en)
|
2016-02-11 |
2019-12-31 |
City Of Hope |
Twist signaling inhibitor compositions and methods of using the same
|
|
WO2017222834A1
(en)
|
2016-06-10 |
2017-12-28 |
City Of Hope |
Compositions and methods for mitochondrial genome editing
|
|
US10646540B2
(en)
|
2016-11-18 |
2020-05-12 |
City Of Hope |
Peptide inhibitors of twist
|
|
US11077173B2
(en)
|
2017-03-13 |
2021-08-03 |
Sdg, Inc. |
Lipid-based nanoparticles and methods using same
|
|
SG11201908052PA
(en)
|
2017-03-13 |
2019-09-27 |
Sdg Inc |
Lipid-based nanoparticles with enhanced stability
|
|
WO2019086626A1
(en)
|
2017-11-03 |
2019-05-09 |
Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (F.S.P.) |
MIRNAs AND COMBINATIONS THEREOF FOR USE IN THE TREATMENT OF HUMAN B CELL NEOPLASIAS
|
|
BR112020013460A2
(pt)
*
|
2018-01-05 |
2020-12-01 |
Sdg, Inc. |
composições compreendendo nanopartículas à base de lipídeo para tratar diabetes mellitus
|