BRPI1007466A2 - conjugado de insulina cristalina, formulação de liberação prolongada, e, sistema de distribuição de bomba - Google Patents
conjugado de insulina cristalina, formulação de liberação prolongada, e, sistema de distribuição de bombaInfo
- Publication number
- BRPI1007466A2 BRPI1007466A2 BRPI1007466A BRPI1007466A BRPI1007466A2 BR PI1007466 A2 BRPI1007466 A2 BR PI1007466A2 BR PI1007466 A BRPI1007466 A BR PI1007466A BR PI1007466 A BRPI1007466 A BR PI1007466A BR PI1007466 A2 BRPI1007466 A2 BR PI1007466A2
- Authority
- BR
- Brazil
- Prior art keywords
- delivery system
- release formulation
- extended release
- pump delivery
- insulin conjugate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/10—Peptides being immobilised on, or in, an organic carrier the carrier being a carbohydrate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14787809P | 2009-01-28 | 2009-01-28 | |
| US15964309P | 2009-03-12 | 2009-03-12 | |
| US16210709P | 2009-03-20 | 2009-03-20 | |
| US16308409P | 2009-03-25 | 2009-03-25 | |
| US21989609P | 2009-06-24 | 2009-06-24 | |
| US21989709P | 2009-06-24 | 2009-06-24 | |
| US22357209P | 2009-07-07 | 2009-07-07 | |
| US25285709P | 2009-10-19 | 2009-10-19 | |
| PCT/US2010/022277 WO2010088300A1 (en) | 2009-01-28 | 2010-01-27 | Crystalline insulin-conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1007466A2 true BRPI1007466A2 (pt) | 2018-06-12 |
Family
ID=42395990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1007466A BRPI1007466A2 (pt) | 2009-01-28 | 2010-01-27 | conjugado de insulina cristalina, formulação de liberação prolongada, e, sistema de distribuição de bomba |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8906850B2 (pt) |
| EP (1) | EP2391646B1 (pt) |
| JP (1) | JP2012516342A (pt) |
| KR (2) | KR20110110253A (pt) |
| CN (1) | CN102341409A (pt) |
| AU (1) | AU2010208319A1 (pt) |
| BR (1) | BRPI1007466A2 (pt) |
| CA (1) | CA2750269A1 (pt) |
| CO (1) | CO6400230A2 (pt) |
| EC (1) | ECSP11011241A (pt) |
| IL (1) | IL214126A0 (pt) |
| MX (1) | MX2011007930A (pt) |
| PE (1) | PE20120582A1 (pt) |
| RU (1) | RU2011135730A (pt) |
| SG (1) | SG173117A1 (pt) |
| WO (1) | WO2010088300A1 (pt) |
| ZA (1) | ZA201105462B (pt) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010088268A1 (en) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Exogenously triggered controlled release materials and uses thereof |
| AU2010208305A1 (en) | 2009-01-28 | 2011-09-08 | Smartcells, Inc. | Synthetic conjugates and uses thereof |
| WO2010088294A1 (en) * | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Conjugate based systems for controlled drug delivery |
| US9095623B2 (en) | 2009-03-20 | 2015-08-04 | Smartcells, Inc. | Terminally-functionalized conjugates and uses thereof |
| US8623345B2 (en) | 2009-03-20 | 2014-01-07 | Smartcells | Terminally-functionalized conjugates and uses thereof |
| WO2012015687A2 (en) * | 2010-07-28 | 2012-02-02 | Smartcells, Inc. | Drug-ligand conjugates, synthesis thereof, and intermediates thereto |
| AU2011282988A1 (en) | 2010-07-28 | 2013-01-31 | Smartcells, Inc. | Recombinantly expressed insulin polypeptides and uses thereof |
| JP2013541500A (ja) | 2010-07-28 | 2013-11-14 | スマートセルズ・インコーポレイテツド | 組換えレクチン、結合部位修飾レクチンおよびそれらの用途 |
| CA2805739A1 (en) * | 2010-07-28 | 2012-02-02 | Smartcells, Inc. | Drug-ligand conjugates, synthesis thereof, and intermediates thereto |
| CN102188367B (zh) * | 2011-01-05 | 2012-11-07 | 山东新时代药业有限公司 | 一种甘精胰岛素注射液及其制备方法 |
| US9457096B2 (en) | 2012-07-06 | 2016-10-04 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Concet) | Protozoan variant-specific surface proteins (VSP) as carriers for oral drug delivery |
| BR112016007176A2 (pt) | 2013-10-04 | 2018-01-23 | Merck Sharp & Dohme | conjugado, composição, usos de um conjugado e de uma composição, e, método para tratar um indivíduo que tem diabete |
| EP3659651A3 (en) | 2014-07-10 | 2020-10-14 | Companion Medical, Inc. | Medicine administering system including injection pen and companion device |
| WO2016164288A1 (en) * | 2015-04-08 | 2016-10-13 | Merck Sharp & Dohme Corp. | Glucose-responsive insulin conjugates |
| CN107530296B (zh) | 2015-04-21 | 2021-06-22 | 北卡罗来纳州立大学 | 使用缺氧敏感性纳米复合材料的葡萄糖响应性胰岛素递送系统 |
| US10946102B2 (en) * | 2016-01-14 | 2021-03-16 | North Carolina State University | Glucose responsive insulin delivery compositions and methods |
| US10864327B2 (en) | 2016-01-29 | 2020-12-15 | Companion Medical, Inc. | Automatic medication delivery tracking |
| EP3463480A1 (en) * | 2016-06-02 | 2019-04-10 | Sanofi | Conjugates of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein |
| CN110167537A (zh) | 2016-11-07 | 2019-08-23 | 北卡罗来纳州立大学 | 用于增强葡萄糖反应性胰岛素的递送的装有双敏感囊泡的贴剂 |
| US11484657B2 (en) | 2017-06-09 | 2022-11-01 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods |
| WO2019075352A1 (en) * | 2017-10-12 | 2019-04-18 | Companion Medical, Inc. | INTELLIGENT DRUG DELIVERY SYSTEMS AND METHODS OF RECOMMENDATION AND DOSE MANAGEMENT |
| CN111433193A (zh) | 2017-12-01 | 2020-07-17 | 赛诺菲 | 药剂和能够结合至葡萄糖传感蛋白的部分的新型缀合物 |
| CN112041936A (zh) | 2017-12-12 | 2020-12-04 | 比格福特生物医学有限公司 | 治疗辅助信息和/或跟踪设备及相关方法和系统 |
| US11083852B2 (en) | 2017-12-12 | 2021-08-10 | Bigfoot Biomedical, Inc. | Insulin injection assistance systems, methods, and devices |
| US11464459B2 (en) | 2017-12-12 | 2022-10-11 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems including flash glucose monitor |
| US10987464B2 (en) | 2017-12-12 | 2021-04-27 | Bigfoot Biomedical, Inc. | Pen cap for insulin injection pens and associated methods and systems |
| US11077243B2 (en) | 2017-12-12 | 2021-08-03 | Bigfoot Biomedical, Inc. | Devices, systems, and methods for estimating active medication from injections |
| US11116899B2 (en) | 2017-12-12 | 2021-09-14 | Bigfoot Biomedical, Inc. | User interface for diabetes management systems and devices |
| US11820805B2 (en) * | 2017-12-18 | 2023-11-21 | Merck Sharp & Dohme Llc | Conjugate based systems for controlled insulin delivery |
| WO2019125879A2 (en) * | 2017-12-18 | 2019-06-27 | Merck Sharp & Dohme Corp. | Conjugate based systems for controlled insulin delivery |
| US10898653B2 (en) | 2018-05-08 | 2021-01-26 | Companion Medical, Inc. | Intelligent medication delivery systems and methods for dose setting and dispensing monitoring |
| US11664107B2 (en) | 2018-05-08 | 2023-05-30 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods using a prescription-regulated software application |
| USD893020S1 (en) | 2018-05-11 | 2020-08-11 | Companion Medical, Inc. | Injection pen |
| USD892819S1 (en) | 2018-06-20 | 2020-08-11 | Companion Medical, Inc. | Display screen with graphical user interface |
| US11587663B2 (en) | 2018-06-20 | 2023-02-21 | Medtronic Minimed, Inc. | Intelligent medication delivery systems and methods for medicine dose calculation and reporting |
| CN110922437B (zh) * | 2018-09-20 | 2023-11-03 | 凯惠科技发展(上海)有限公司 | 一种葡萄糖类化合物、药物组合物及其应用 |
| US11948671B2 (en) | 2019-04-11 | 2024-04-02 | Medtronic Minimed, Inc. | Intelligent accessories for medicine dispensing device |
| EP4003405A4 (en) * | 2019-07-30 | 2023-08-23 | Merck Sharp & Dohme LLC | GLUCOSE-RESPONDING INSULIN CONJUGATES |
| US11701473B2 (en) | 2021-06-23 | 2023-07-18 | Medtronic Minimed, Inc. | Reusable injection pens |
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-
2010
- 2010-01-27 RU RU2011135730/04A patent/RU2011135730A/ru not_active Application Discontinuation
- 2010-01-27 BR BRPI1007466A patent/BRPI1007466A2/pt not_active IP Right Cessation
- 2010-01-27 CA CA2750269A patent/CA2750269A1/en not_active Abandoned
- 2010-01-27 SG SG2011053378A patent/SG173117A1/en unknown
- 2010-01-27 WO PCT/US2010/022277 patent/WO2010088300A1/en active Application Filing
- 2010-01-27 MX MX2011007930A patent/MX2011007930A/es not_active Application Discontinuation
- 2010-01-27 KR KR1020117017642A patent/KR20110110253A/ko active IP Right Grant
- 2010-01-27 JP JP2011548261A patent/JP2012516342A/ja active Pending
- 2010-01-27 AU AU2010208319A patent/AU2010208319A1/en not_active Abandoned
- 2010-01-27 KR KR1020147008437A patent/KR20140054404A/ko not_active Application Discontinuation
- 2010-01-27 PE PE2011001412A patent/PE20120582A1/es not_active Application Discontinuation
- 2010-01-27 CN CN201080009857XA patent/CN102341409A/zh active Pending
- 2010-01-27 EP EP10736359.0A patent/EP2391646B1/en active Active
- 2010-01-27 US US13/145,525 patent/US8906850B2/en active Active
-
2011
- 2011-07-17 IL IL214126A patent/IL214126A0/en unknown
- 2011-07-25 ZA ZA2011/05462A patent/ZA201105462B/en unknown
- 2011-07-28 EC EC2011011241A patent/ECSP11011241A/es unknown
- 2011-07-28 CO CO11095151A patent/CO6400230A2/es active IP Right Grant
-
2014
- 2014-05-19 US US14/280,793 patent/US9463249B2/en active Active
-
2016
- 2016-10-07 US US15/288,362 patent/US20170022262A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20170022262A1 (en) | 2017-01-26 |
| JP2012516342A (ja) | 2012-07-19 |
| EP2391646A1 (en) | 2011-12-07 |
| ZA201105462B (en) | 2015-01-28 |
| SG173117A1 (en) | 2011-08-29 |
| RU2011135730A (ru) | 2013-03-10 |
| EP2391646B1 (en) | 2016-08-10 |
| IL214126A0 (en) | 2011-08-31 |
| MX2011007930A (es) | 2011-09-06 |
| US20140275476A1 (en) | 2014-09-18 |
| US20110281791A1 (en) | 2011-11-17 |
| CO6400230A2 (es) | 2012-03-15 |
| KR20110110253A (ko) | 2011-10-06 |
| CN102341409A (zh) | 2012-02-01 |
| PE20120582A1 (es) | 2012-05-26 |
| AU2010208319A1 (en) | 2011-08-11 |
| ECSP11011241A (es) | 2011-11-30 |
| US9463249B2 (en) | 2016-10-11 |
| KR20140054404A (ko) | 2014-05-08 |
| CA2750269A1 (en) | 2010-08-05 |
| US8906850B2 (en) | 2014-12-09 |
| EP2391646A4 (en) | 2012-06-27 |
| WO2010088300A1 (en) | 2010-08-05 |
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